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Cell Division 
Presented by IB Screwed 
www.ibscrewed.org
Mitosis 
Mitosis is division of the nucleus into two genetically identical daughter nuclei. 
The process is important for development, tissue repair and growth 
Mitosis is a continuous process with no breaks in it, although we divide it into four stages.
Behaviour of the chromosomes 
Chromosomes condense by supercoiling during mitosis. 
Normally, during interphase, DNA is loosely arranged 
The chromosomes must condense so that they can be distinguished and separated 
They shorten and thicken through the process of supercoiling.
Cytokinesis 
Cytokinesis occurs after mitosis and is different in plant and animal cells. 
It is the division of the cytoplasm to form two daughter cells.
Interphase 
Interphase is a very active phase of the cell cycle with many processes occurring in the nucleus and cytoplasm. 
The cell will be performing its ‘normal’ functions such as respiration, photosynthesis, protein synthesis and growth. 
There are three parts of interphase: 
G1 -During this time, a high amount of protein synthesis occurs and the cell grows, more organelles are produced, and the mitochondriaandchloroplastsdivide. 
S -the cell replicates its DNA 
G2 -the cell resumes its growth in preparation for division.
Cyclins 
Cyclinsare involved in the control of the cell cycle. 
When cyclinsare synthesized, they act as an activating protein and bind to Cdksforming a cyclin-Cdkcomplex. 
This complex then acts as a signal to the cell to pass to the next cell cycle phase. Eventually, the cyclindegrades, deactivating the Cdk, thus signalling exit from a particular phase.
Cancer 
Mutagens, oncogenes and metastasis are involved in the development of primary and secondary tumours. 
Tumours, or cancers, are cell mass formed as a result of uncontrolled cell division. They can occur in any tissue. 
Cancer is caused by damage to DNA chromosomes 
The tumour will eventually take over and destroy healthy cells 
Common mutagens include: ionising radiation, chemicals and viruses
Tobacco and Cancer 
The tar in tobacco cigarette smoke is a chemical mutagen. 
Consequently, there is a correlation between smoking and incidence of cancers. 
Suppression of the results of research by tobacco companies into the health effects of smoking tobacco was unethical. 
Smoking causes considerable social harm, but, with the exception of laws on production and supply in Bhutan, has never been made illegal.

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Cell division

  • 1. Cell Division Presented by IB Screwed www.ibscrewed.org
  • 2. Mitosis Mitosis is division of the nucleus into two genetically identical daughter nuclei. The process is important for development, tissue repair and growth Mitosis is a continuous process with no breaks in it, although we divide it into four stages.
  • 3. Behaviour of the chromosomes Chromosomes condense by supercoiling during mitosis. Normally, during interphase, DNA is loosely arranged The chromosomes must condense so that they can be distinguished and separated They shorten and thicken through the process of supercoiling.
  • 4. Cytokinesis Cytokinesis occurs after mitosis and is different in plant and animal cells. It is the division of the cytoplasm to form two daughter cells.
  • 5. Interphase Interphase is a very active phase of the cell cycle with many processes occurring in the nucleus and cytoplasm. The cell will be performing its ‘normal’ functions such as respiration, photosynthesis, protein synthesis and growth. There are three parts of interphase: G1 -During this time, a high amount of protein synthesis occurs and the cell grows, more organelles are produced, and the mitochondriaandchloroplastsdivide. S -the cell replicates its DNA G2 -the cell resumes its growth in preparation for division.
  • 6. Cyclins Cyclinsare involved in the control of the cell cycle. When cyclinsare synthesized, they act as an activating protein and bind to Cdksforming a cyclin-Cdkcomplex. This complex then acts as a signal to the cell to pass to the next cell cycle phase. Eventually, the cyclindegrades, deactivating the Cdk, thus signalling exit from a particular phase.
  • 7. Cancer Mutagens, oncogenes and metastasis are involved in the development of primary and secondary tumours. Tumours, or cancers, are cell mass formed as a result of uncontrolled cell division. They can occur in any tissue. Cancer is caused by damage to DNA chromosomes The tumour will eventually take over and destroy healthy cells Common mutagens include: ionising radiation, chemicals and viruses
  • 8. Tobacco and Cancer The tar in tobacco cigarette smoke is a chemical mutagen. Consequently, there is a correlation between smoking and incidence of cancers. Suppression of the results of research by tobacco companies into the health effects of smoking tobacco was unethical. Smoking causes considerable social harm, but, with the exception of laws on production and supply in Bhutan, has never been made illegal.