This document presents information on the design of cosmeceutical products, specifically focusing on sunscreen products. It discusses the introduction and classification of sunscreens, ideal properties of sunscreen agents, how to select a sunscreen based on skin type, and SPF values. The document provides details on physical and chemical sunscreen classifications, and recommendations for SPF levels based on different skin types and their proclivity to burn or tan. It aims to educate on proper sunscreen selection and design of cosmeceutical products for sun protection.

1. DEPARTMENTOFPHARMACEUTICS
TOPIC: Design of cosmeceutical products
PRESENTED BY: RUSHIKESH SHINDE
(M.Pharm,First Year)
GUIDED BY: DR.NALANDA BORKAR
(Head Of Department Of Pharmaceutics)
Survey No. 50,Marunje,Near Rajiv Gandhi,
IT Park, Hinjawadi,Pune,Maharashtra,411028
ALARD COLLEGE OF PHARMACY

2.  CONTENT:
Introduction
Sunscreen
Sunscreen Classification
Ideal sunscreen agent
Skin type & choice of sunscreen
SPF value

3.  INTRODUCTION TO COSMECEUTICAL:
 Cosmeceutical is an ingredient with medicinal
manifests beneficial topical action and provide
degenerative skin conditions.
properties, which
protection against
 Are cosmetic product with biologically active ingredient purpoting to
have medical or drug like benefits.
 The FD & C act does not recognize any such category as
cosmeceutical “A product can be drug ,a cosmetic or a combination
of both,but the term “cosmeceutial “has no meaning under thelaw.
 Are product that have both cosmetic and therapeutics effect
and are intended to have beneficial effect on skin health and
beauty.
 Cosmetical are available “over the counter “ & are generally used
as a part of a regular skin care regime to help improve skin tone
and texture,pigmentation and fine lines

4.  Sun Protection:
Introduction:
 Radiation of wavelength 2000-2500A° : penetrate the blood
veseels reaching the papillary layer.
 3200 -3900 A° : reach dermal
 2800-3200 A° : are both erythemogenic ( capble ofproducing
redness ) & pigmentogenic.
 More than 3900 A° : heating action.
 Intensity of erythema depend on absorption of ultra violet
radiation.
 Three type of skin tannings : 1. immediate tanning
 delayed tanning
 true tanning

8.  sun burns are the result of damage or destruction of cell in the
prickle cell
 layer of epidermis
 Histamine like substance released by the damaged or destructed
cell causes dilation of blood vessel & erythma . These substance
also cause swelling of the skin and stimulate basal cell to
proliferate.
 Sun burn classified into four degree:
 Degree 1: minimum
erythema degree 2 :
vivid erythema degree
3 : painful burn
degree 4 : blistering
burn

9.  Purpose of suntan preparation is to assist the skin in tanning without
painful effect & the purpose of anti-burn preparation is to minimize the
harmful effect of the sunburn.
 A number of organic compound have been screened for
sunscreening properties:
 Azole
 P-aminobenzoic acid & its derivatives.
 Cinnamic acid derivatives
 Coumarin derivatives
 Quinine salt
 Dibenzalactone & benzal actophenone
 Hydrocarbon
 Hydroquinone
 Uric acid & violuric acid
 anthraniltes
 Sunscreen:

10. Sunscreen classification :
A) Physical:
Opaque formulation containing :
 titanium dioxide
 talc , kaolin
 zinc oxide
 Ferric chloride
 red petrolatum
- Mechanism : scatters of reflects UV radiation due to
large particles size .

11. B) Chemical:
- formulation containing one or more :
 PABA ,PABAester
 benzophenones
 cinnamates
 salicylates
 digalloyl trioleate
 anthranilates
Mechanism : absorbs UV radiation

12.  Ideal sunscreen agent:
 It should absorb erythonogenic radiation in the range of 290-
320nm without its break down.
 Its should allow full transmission of radiation in the range of 300-
400nm for tanning effect.
 Should be resistant to water & perspiration & should also be non-
volatile.
 Should have suitable solubility characteristics.
 Odourless or should have only mild characteristics.
 Non-toxic, non -irritant and non-sensitizing.
 Should be capable of retaining its sunscreening property for
several hours.
 Should be stable under condition of use.
 Should not stain.

13.  Skin type & choice of sunscreen:
• Always burns easily & never tan
(i.e.sensitive) always burns & tan
minimally
• burns moderately & tan gradually to a shade of light
brown (i.e.normal)
• burn minimally & always tans well (i.e.normal)
• barely burn & tans profusely skin become dark brown
(i.e.Insensitive) never burn & skin become deeply
pigmented.
 US FDA classification system for sunscreen product comprises of five
product category designation (PCD) to meet requirement of
consumers with different type of skin.
 Depending upon skin type & tanning history they are classified into six
group :

14.  SPF value:
 The SPF has been defined as ratio between the UV exposure required
to produce a minimally perceptible erythema on protected skin & the
exposure that will produce the erythema on unprotected skin
 The formal defination of SPF by the OTC Panel of the US FDAwas
SPF value : MED (PS) / MED (US)
PS : minimum erythemal dose for protected skin after the application of
2mg/cm² of the final formulation of the sunscreen product.
US : minimum erythemal dose for unprotected skin i.e.skin to which no
sunscreen product has been applied .
the larger the SPF , the greater the sun protection
 For skin type mentioned above , sunscreening product with the
following SPF are recommended.

22.  REFERENCES:
 Handbook of cosmetic science and Technology A.O.Barel, M.Paye
and H.I. Maibach. 3 rd edition. Accessed Date:11 June 2021.
 Cosmetics –Formulation, Manufacture and quality control,
PP.Sharma,4th edition. Accessed Date:11 June 2021.
 https://www.slideshare.net/prashantlpingale/sunscreen-
preparations. Accessed Date:11 June 2021.
 www.googleimages/sunscreenimges,Accessed Date:11 June 2021.