Cosmeceuticals are topically applied products with medicinal benefits for the skin. They fall between cosmetics and drugs. Some key points:
- Cosmeceuticals were coined in 1980 and contain ingredients that protect against skin damage.
- The FDA does not recognize cosmeceuticals as a separate category - a product is either a drug, cosmetic, or combination.
- Common cosmeceutical ingredients include antioxidants, peptides, retinoids, and exfoliants which treat signs of aging.
- Safety testing evaluates irritation potential, phototoxicity and other factors to ensure cosmeceuticals are safe for long-term use. Instrumental methods objectively measure skin
cosmetic and cosmeceutical
Classification of cosmetic and cosmeceutical products
Definition of cosmetics as per Indian and EU regulations, Evolution of cosmeceuticals from cosmetics, cosmetics as quasi and OTC drugs
Cosmetic excipients: Surfactants, rheology modifiers, humectants, emollients, preservatives. Classification and application
Skin: Basic structure and function of skin.
Hair: Basic structure of hair. Hair growth cycle.
Oral Cavity: Common problem associated with teeth and gums
Analytical cosmetics:BIS specification and analytical methods for shampoo, sk...Steffi Thomas
Analytical cosmetics:BIS specification and analytical methods for shampoo, skin-cream and toothpaste, Indian standards, Schedule S and Schedule Q, Drugs and cosmetic act, standards for heavy metals in cosmetics, standards for coloring agents in cosmetics, annexures, list of approved colours and dyes as per schedule Q Part 1, list of colours permitted to be used in soaps, types of toothpaste, general requirements for ECO mark and BIS mark, BIS certification marking
Deodorants and antiperspirants Cosmetic SciencePranjal Saxena
This presentation contains about description of Deodorants and antiperspirants with their Action, Evaluation, Difference between Deodorants and antiperspirants.
cosmetic and cosmeceutical
Classification of cosmetic and cosmeceutical products
Definition of cosmetics as per Indian and EU regulations, Evolution of cosmeceuticals from cosmetics, cosmetics as quasi and OTC drugs
Cosmetic excipients: Surfactants, rheology modifiers, humectants, emollients, preservatives. Classification and application
Skin: Basic structure and function of skin.
Hair: Basic structure of hair. Hair growth cycle.
Oral Cavity: Common problem associated with teeth and gums
Analytical cosmetics:BIS specification and analytical methods for shampoo, sk...Steffi Thomas
Analytical cosmetics:BIS specification and analytical methods for shampoo, skin-cream and toothpaste, Indian standards, Schedule S and Schedule Q, Drugs and cosmetic act, standards for heavy metals in cosmetics, standards for coloring agents in cosmetics, annexures, list of approved colours and dyes as per schedule Q Part 1, list of colours permitted to be used in soaps, types of toothpaste, general requirements for ECO mark and BIS mark, BIS certification marking
Deodorants and antiperspirants Cosmetic SciencePranjal Saxena
This presentation contains about description of Deodorants and antiperspirants with their Action, Evaluation, Difference between Deodorants and antiperspirants.
Sun Protection (Classification of Sunscreen and SPF)Rahul Kushwaha
Introduction
Skin Damage
Sun Radiation Summary
Sunscreen Defination
Classification Of Sunscreen
Sunscreen Agents
Sun Protection Factor
Sun Protection Factor Classification
When to re-apply the sunscreen
Classification of Sunscreens and SPF and Role of herbs in cosmetics:Priya Patil
Sun protection,
Classification of Sunscreens and SPF.
Role of herbs in cosmetics:
Skin Care: Aloe and turmeric
Hair care: Henna and amla.
Oral care: Neem and clove
Antiperspirant & Deodorant:A deodorant is a substance applied to the body to prevent body odor caused by the bacterial breakdown of perspiration in armpits, feet, and other areas of the body. A subgroup of deodorants, antiperspirants, affect odor as well as prevent sweating by affecting sweat glands.
Antiperspirants are typically applied to the underarms, while deodorants may also be used on feet and other areas in the form of body sprays. In the United States, the Food and Drug Administration classifies and regulates most deodorants as cosmetics, but classifies antiperspirants as over-the-counter drugs.
Mechanism perspiration control
Sweating allows the body to regulate its temperature. Sweating is controlled from a center in the periotic and anterior regions of the brain's hypothalamus, where thermo sensitive neurons are located. The heat-regulatory function of the hypothalamus is also affected by inputs from temperature receptors in the skin.
ATUL CHAUDHARY (STUDENT)
DEPARTMENT OF PHARMACEUTICS
ISF COLLEGE OF PHARMACY, GHALKALAN MOGA, PUNJAB
THIS PRESENTATION IS THE BEST PRESENTATION FOR PREPARING THE TOPOC COSMECEUTICALS SPECIALLY FOR MASTER STUDENTS AS WELL AS GRADUATION STUDENTS PURPOSE,
THANKU
Sun Protection (Classification of Sunscreen and SPF)Rahul Kushwaha
Introduction
Skin Damage
Sun Radiation Summary
Sunscreen Defination
Classification Of Sunscreen
Sunscreen Agents
Sun Protection Factor
Sun Protection Factor Classification
When to re-apply the sunscreen
Classification of Sunscreens and SPF and Role of herbs in cosmetics:Priya Patil
Sun protection,
Classification of Sunscreens and SPF.
Role of herbs in cosmetics:
Skin Care: Aloe and turmeric
Hair care: Henna and amla.
Oral care: Neem and clove
Antiperspirant & Deodorant:A deodorant is a substance applied to the body to prevent body odor caused by the bacterial breakdown of perspiration in armpits, feet, and other areas of the body. A subgroup of deodorants, antiperspirants, affect odor as well as prevent sweating by affecting sweat glands.
Antiperspirants are typically applied to the underarms, while deodorants may also be used on feet and other areas in the form of body sprays. In the United States, the Food and Drug Administration classifies and regulates most deodorants as cosmetics, but classifies antiperspirants as over-the-counter drugs.
Mechanism perspiration control
Sweating allows the body to regulate its temperature. Sweating is controlled from a center in the periotic and anterior regions of the brain's hypothalamus, where thermo sensitive neurons are located. The heat-regulatory function of the hypothalamus is also affected by inputs from temperature receptors in the skin.
ATUL CHAUDHARY (STUDENT)
DEPARTMENT OF PHARMACEUTICS
ISF COLLEGE OF PHARMACY, GHALKALAN MOGA, PUNJAB
THIS PRESENTATION IS THE BEST PRESENTATION FOR PREPARING THE TOPOC COSMECEUTICALS SPECIALLY FOR MASTER STUDENTS AS WELL AS GRADUATION STUDENTS PURPOSE,
THANKU
Addressing wrinkles, body odor & dandruff through cosmeceutical preparationsMonika Dovulary
This presentation is a precise yet descriptive information of the topic and will be of extreme use to postgraduate students.
I hope this will be of great help.
Cosmeceuticals have become the fastest-growing segment of the personal care industry. About 25 years ago Dr. Albert Kligman of the University of Pennsylvania originally coined the term ‘cosmeceutical’, describing a hybrid category of products found on the spectrum between drugs and cosmetics that exert a pharmaceutical therapeutic benefit but not necessarily a biological therapeutic benefit.
A presentation about anti-aging creams giving a brief of aging, anti-aging cosmetics, some general and some modern anti-aging agents and their mechanism of action, some detailed info of marketed formulations
Ultraviolet radiation (UVR) has been shown to cause skin disorders, including sunburn and symptoms such as erythema, ageing and formation of wrinkles, pigmentation or dyspigmentation, DNA damage and ultimately photocarcinogenesis on prolonged exposure. It has been reported that sunscreens have beneficial effects in reducing the incidence of skin disorders and protect the skin against exogenous and endogenous harmful agents by absorption, scattering and by blocking phenomena. Ultraviolet (UV) rays are classified into three wavelengths UV-A, UV-B and UV-C. The generation of reactive oxygen species (ROS), which can react with DNA, proteins, and fatty acids in the skin causes oxidative damage and impairment of antioxidant system in the human body is triggered by skin exposure to sunlight and other climatic circumstances. Such injuries disrupt the skin’s regulation pathways, causing photoaging and the development of skin cancer. Active ingredient of sunscreen agents are synthetic substances which are divided into organic and inorganic filters used in the market. Synthetic agents have shown some serious side effects. Therefore, to overcome this deleterious effects natural sunscreens were found by the researchers from nature. Natural products are efficacious as sunscreens and produce healing, softening, rejuvenating, and sunscreen effects. However, the use of sunscreen has faced many challenges, including inducing photoallergic dermatitis, environment pollution, and deficiency of vitamin D production. Therefore, consumers should efficiently apply suitable herbal formulations to improve sun protection as well as to avoid the side effects of synthetic sunscreens.
Rodan + Fields is well positioned to take a significant part of the $2.9 billion dollar market, which is expected to double in the next 3 to 5 years. Remember how the Doctors captured the acne market with Proactiv? Look out for our MOMENTUM as Rodan + Fields and our independent business partners take over the anti-aging market. Contact me to get on my list to be one of the first to try this amazing system. Incentives for hosts of launch parties. I'm also looking for new business partners across the U.S. and Canada to launch their business and penetrate their respective markets. This truly is the opportunity of a lifetime and it only happens once. Be one of the FIRST! Get in touch today! Visit http://www.victoriaskincare.net and follow the links.
Matrix Fine Sciences is a Life science division of a fifty year old group which has intense and diverse manufacturing experience in Nutraceutical industry. We are highly process oriented company and a global supplier today catering to Nutaceutical, Cosmetic, Food, and Pharma industries.
Matrix fine sciences is specialised in extraction of Natural Tocopherol( Vitamin E). Natural Vitamin E is used in various cosmetics applications as an anti aging, anti pimple, sun screen. It maintains healthy skin and adds value to Beauty.
Matrix Fine Sciences is a Life science division of a fifty year old group which has intense and diverse manufacturing experience in Nutraceutical industry. We are highly process oriented company and a global supplier today catering to Nutaceutical, Cosmetic, Food, and Pharma industries.
Matrix fine sciences is specialized in extraction of Natural Tocopherol( Vitamin E) from 100 % Non GMO Soy and Sunflower.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
How to Create Map Views in the Odoo 17 ERPCeline George
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Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
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The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
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Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
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2. A cosmeceutical is an ingredient with medicinal
properties, which manifests beneficial topical
actions and provides protection against
degenerative skin conditions
The term cosmeceutical was
coined in 1980 by the
dermatologist Albert kligman
3. The FD&C Act does not recognize
any such category
as "cosmeceuticals." A product can
be a drug, a cosmetic, or a
combination of both, but the term
"cosmeceutical" has no meaning
under the law.
Cosmetics COSMECUTICALS
4. "articles intended to be rubbed, poured,
sprinkled, or sprayed on, introduced into, or
otherwise applied to the human body...for
cleansing, beautifying, promoting
attractiveness, or altering the appearance"
DRUG
"articles intended for use in the diagnosis, cure,
mitigation, treatment, or prevention of disease"
and "articles (other than food) intended to affect
the structure or any function of the body of man
or other animals
COSMETICS
According to FD&C Act.
6. A deodorant is a cosmetic but an antiperspirant is a drug
A shampoo is a cosmetic but an antidandruff shampoo is a drug
A suntan product is a cosmetic but a sunscreen product is a drug
A skin exfoliant is a cosmetic but a skin peel is a drug
A skin product to hide acne is cosmetic but an antiacne product is a
drug
A skin moisturizer is a cosmetic but a wrinkle remover is a drug
An antibacterial deodorant soap is a cosmetic but an antibacterial anti-
infective soap is
a drug
A lip softener is a cosmetic but a product for chapped lips is a drug
A toothpaste is a cosmetic but an anticaries toothpaste is drug
A mouthwash is cosmetic but an antigingivitis mouth wash is a drug
7. •Uv protection
•Exfoliants
•Alpha hydroxy acids
Lactic acid
Glycolic acid
•Beta hydroxy acids
•Retinoids
•Moisturizers
•Antioxidants
•Peptides
•De-pigmenting agents
List of common ingredient used in cosmeceuticals
8. UVA wavelengths penetrate deeply into the dermis, causing
skin to wrinkle.
UVB radiation is associated with many skin cancers.
The SPF number on sun blockers only applies to UVB
protection and has no connection with UVA protection. A SPF
number of 30 is recommended for daily use.
Higher numbers do not proportionately increase protection.
•Uv protection
•Exfoliants
Exfoliants remove dead cells and the outer
layers of thickened skin, encouraging skin
turnover.
•Alpha hydroxy acids
Softens fine wrinkles, lightens pigmentation
spots, generally tightens and improves skin
texture. Makes skin look healthier and
more radiant
9. •Retinoids
Treats mild to moderate acne and photo-
damaged skin, removes dead surface
cells, Claims to build collagen, regenerate
the skin’s elasticity and
•Antioxidants
•Moisturizers
Moisturizers smooth the surface of the
skin, lubricate its outer layers, and lock in
moisture.
Antioxidants, the ingredients meant to
defend against free radical damage
Vitamin A & C
Resveratrol
Green tea
Co-enzyme Q-10
Algae
10. peptides that may stimulate skin
metabolism and repair, while others
may inhibit hyperpigmentation,
slow the breakdown of collagen
•Peptides
Eg: Argireline
11. Aging results from cumulative damage to tissues
that overwhelm the body's natural ability to repair
them. The tell tale signs of aging on the skin include
discoloration, wrinkles, and texture loss
These effects result from
•Genetically programmed chronological aging
•Photoaging - sun exposure
•Environmental and lifestyle factors –
damage by chemicals, pollutants, smoking,
etc.
Why Does Skin Age??
12. Certain synthetic organic substances or sunscreens have
molecular structures that are capable of "filtering out" the
harmful UV rays by mechanisms including absorption,
reflection or diffusion.
Examples include avobenzone, sulisobenzone, aminobenzoic
acid, titanium oxide, zinc oxide and others. Such ingredients
appear in the FDA monograph on sunscreen agents.
Sunscreens are regulated as over the counter drugs by the
FDA.
The efficacy of sunscreens is measured as SPF (sun
protection factor).
What are Sunscreens?
13. UV damage is manifested as
• sunburn,
• skin discoloration
•texture loss.
UV rays also trigger skin aging through:
Free radical reactions and oxidative stress.
Increased activity of enzymes such as collagenase
and elastase that are catalyzed by metal ions.
Effect of UV Rays
Photoaging - sun exposure
14. The results are:
Abnormal cross linking of Collagen
fibers
Scar tissue build up and visible
wrinkles and skin discoloration
Ravages of chronological aging are
accelerated
15. Drug Name Concentration % Absorbance
Aminobenzoic acid up to 15 UVB
Avobenzone 2-3 UVA I
Cinoxate up to 3 UVB
Dioxybenzone II up to 3 UVB, UVA I & II
Homosalate up to 15 UVB
Menthyl anthranilate up to 5 UVA II
Octyl methoxycinnamate up to 7.5 UVB
Octisalate up to 5 UVB
Oxybenzone up to 5 UVB
Padimate O up to 8 UVB
Phenylbenzimidazole sulfonic acid up to 4 UVB
Sulisobenzone up to 10 UVB, UVA II
Titanium dioxide 2-25 Physical
Trolamine salicylate up to 12 UVB
Zinc oxide 2-20 Physical
The sunscreens listed in the FDA OTC monograph
16. Several natural extracts protect the skin from the
damaging effects of UV rays:
•Tetrahydrocurcuminoids
•SabiWhite
•Green tea Extract
•Sesame antioxidants
•Umbelliferin
•Xylosin
•Rosemary extract
•Rosmarinic acid
•Lupeol
•Arjunolic acid
17. •In vitro testing
•Cumulative Irritation testing
•Repeat Insult Patch Tests (RIPT)
•Sensitization
•Ocular Irritation
•Facial Sting
•Phototoxicity
•Photoallergy
•Comedogenicity
•Acnegenicity
Product Safety Testing
Testing needs are determined by the company
marketing the product .May include:
18. Dermal irritation: is
defined as the production
of “reversible damage of
the skin following the
application of a test
substance for up to 4
hours”. Tests used to
study dermal irritation:
1. EPISKIN™ human skin
model.
2. 2. EpiDerm™ human
skin model.
3. 3. PREDISKIN™
human skin model. 4.
Pig ear test.
19. Examples of Instrumental Measurements
Parameter Instrument
Moisturization Conductance/Impedance
Skin barrier function TEWL(Transepidermal Water Loss)
Skin texture Topography
Skin elasticity Elastometer
Skin thickness Ultrasound
Blood flow Laser Doppler
Sebum (oiliness) Sebumeter
Color Chromameter
21. •Safe for long-terms use
•Promote beauty throught health and wellness of skin
•cosmeceuticals with natural ingredients are preferred
Advantage of cosmeceuticals
22. 1) Textbook of Industrial Pharmacy: Delivery Systems, &
Cosmetics & Herbal Technology. by Shobha Rani Hiremath,
Universities Press. Page no. 291- 301
2) Food & Drug Administration (FDA)
http://www.fda.gov/
3) Cosmetic, Toiletry, and Fragrance Association (CTFA)
http://www.ctfa.org
4) Thornfeldt C. Cosmeceuticals containing herbs: fact, fiction, and
future. Dermatol Surg. Jul 2005;31(7 Pt 2):873‐80;
REFERENCE
