This document discusses the formulation of nanoparticles for use in cosmetics. It begins with an introduction to cosmeceuticals and nanocosmeceuticals. It then discusses the importance of nanocosmeceuticals and challenges in the field. The document classifies different types of nanoparticles used in cosmetics and provides examples of research done in areas like sunscreen, anti-aging cream, moisturizer, and face wash. Methods for formulating nanoparticles for sunscreen, anti-aging cream, moisturizer, and face wash are also summarized. The document concludes that nanotechnology has benefits for cosmetic products and the cosmetics market is growing.

1. DELHI PHARMACEUTICAL SCIENCES AND
RESEARCH UNIVERSITY
SEMINAR ASSIGNMENT
FORMULATION OF NANOPARTICLES
SUBMITTED TO :- SUBMITTED BY :-
Dr. MADHU GUPTA KUMARI SUPRIYA
OSD TO VC M.PHARMA COSMECEUTICS
ASSOCIATE PROFESSOR 2nd SEMESTER
72/MPH/DPSRU/19

2.  INTRODUCTION
 IMPORTANCE OF NANOCOSMECEUTICALS
 NANOCOSMECEUTICALS:CHALLENGES,
OPPORTUNITY, APPLICATION
 CLASSIFICATION
 NANOPARTICLES USED FOR COSMETICS
 RESEARCH DONE IN THIS AREA
 PATENTED TECHNOLOGY
 FORMULATION OF NANOPARTICLES
1.Sunscreen
2.Anti-aging cream
3.Moisturizer
4.Face wash
 CONCLUSION
 REFERENCES

3. INTRODUCTION
COSMETICS - ‘substance that are intended or
rubbed, sprinkled and sprayed or applied on
skin for beautifying, cleansing, promoting
attractiveness or altering appearance’.
COSMECEUTICALS - A cosmetic product claimed
to have medicinal or drug-like benefits.
(COSME)TIC + PHARMA(CEUTICALS)

4. NANOCOSMECEUTICALS – ‘those beauty
products generally contain either engineered
‘nanomaterials’ or ‘nanoparticles’.
NANOTECHNOLOGY
NANOCOSMECEUTICALS
COSMETIC PHARMACEUTICALS

5. IMPORTANCE
OF
NANOCOSME
CEUTICALS
LOAD HIGH
AMOUNT OF
ACTIVE
INGREDIENTS
BETTER
EFFICACY
SITE SPECIFIC
TARGETING
INCREASE
RESIDENCE OF
ACTIVE
INGREDIENTS
PROTECT
CHEMICAL &
ENZYMATIC
DEGRADATION
AVOID SKIN
IRRITATION
PENETRATE IN
DEEPER
LAYERS
CONTROLLED
RELEASE

6. NANOCOSMECEUTICALS: CHALLENGES,
OPPORTUNITY, APPLICATION
 CHALLENGES – 1. Incompatibility.
2. Nanotoxicity – Shape, size, cellular toxicity, inhalation, ingestion
environmental risk.
3. No regulation for clinical safety.
4. No clinical trails.
OPPORTUNITY - 1. Protect skin from sunburn.
2. Phyto-based nanocosmeceuticals play a greater role in future
for enhanced protective benefits and health benefits.
3. Higher efficacy in skin based nanotehrapy.

7. NANOCOSMECEUTICALS: CHALLENGES,
OPPORTUNITY, APPLICATION contd.
 APPLICATION – 1. Beauty and skin therapy.
2. Biomedical
3. Bio-sensing

8. NANOCOSMECEUTICALS CLASSIFICATION
HAIR CARE SKIN CARE NAIL CARE LIP CARE
HAIR SERUM
SHAMPOO
CONDITIONER
GROWTH
STIMULATOR
HAIR GEL
HAIR COLOR
SUNSCREEN
MOISTURIZER
ANTI AGING
FACE WASH
ANTI ACNE
EYE CREAM
NAIL
LACQUER
LIPSTICK
LIP BALM
LIP GLOSS
LIP
VOLUMIZER

9. NANOPARTICLES USED FOR COSMETICS
Nanoparticles as
UV filters
Liposomes Nanocapsule Solid Lipid Nanoparticles
Dendrimers
Nanogold &
Nanosilver
Cubosomes Niosomes

10. RESEARCH DONE IN THIS AREA
 NANOEMULSION (Lotion, Shampoo, Nail enamel, Conditioners, Hair Serum)
 LIPOSOME (Anti-aging Cream)
 NIOSOME (Foundation)
 NANOCAPSULE (Primer)
 SOLID LIPID NANOPARTICLES (Body cream, Perfume, Anti-aging Cream)
 NANOCRYSTAL (Anti-wrinkle Cream)
 DENDRIMERS (Nail Lacquer)
 NANOGOLD & NANOSILVER (Deodorant, Face Pack, Anti-aging Cream)
 CUBOSOMES (Antiperpirants)
 FULLERENS (Anti-acne products)
 CHITIN NANOFIBRILS (Anti-aging Cream)

11. PATENTED TECHNOLOGY
NANOSOLVE – This patented technology is used for patenting
nanoformulations.
Some common patents in cosmeceuticals –
Cosmetic composition containing retinol stabilized by porous polymer beads and
nanoemulsion.
Multiactive microtargeted antiaging skincream polymer technology.
Semipermanent mascara and method of applying.
Metal oxide noncomposites for UV protection.
Deodorant composition.
O/W type emulsion sunscreen cosmetic composition.

12. FORMULATION OF NANOPARTICLES
• SUNSCREEN – In formulating sunscreen nanoparticles of Titanium Dioxide and
Zinc Oxide are used as UV filters.
• Mainly sunscreen containing nanoparticles are used because these ultra-fine
nanoparticles make the sunscreen less opaque.
Preparation Methods – Laser ablation, Hydrothermal methods,
Electrochemical depositions, Sol-gel method, Chemical-vapour
deposition, Thermal decomposition, Combustion method, Ultrasound
Nanoparticle is ultrafine particle usually defined as a particle of matter
whose size in between 1 to 100nm in diameter.

13. FORMULATION OF NANOPARTICLES contd.
• ANTI-AGING CREAM - Antiaging products are the main cosmeceuticals in the
market currently being made using nanotechnology.
• L'Oreal has employed nanotechnology in products such as Revitalift antiwrinkle
cream which contains nanosomes of Pro-Retinol A, and claims that it instantly
rejuvenates the skin and reduces the appearance of wrinkles.
• Lancôme introduces Hydra Zen Cream to renew the skin's healthy look which contains
nanoencapsulated Triceramide.
Some Nano based products –
 Nanogold firming treatment (Chantecaille)
 Nanosphere plus (DermaSwiss)
 Zelens Fullerene C-60 Night Cream (Zelens)

14. FORMULATION OF NANOPARTICLES contd.
• MOISTURIZER - . Moisturizers contain ingredients that are either occlusive
(blocking) or humectant. Nanoparticle based moisturizer are mainly used for its better
efficacy property- it show better action than conventional ones.
• Liposomes, nanoemulsions, SLNs are widely used moisturizing formulations because of
their prolonged effects.
Some Nano-based products –
 Hydra Flash Bronzer Daily Face moisturizer (Lancome)
 Hydra Zen Cream (Lancome)
 Nano-In Hand and Nail Moisturizing Serum and
Foot Moisturizing Serum (Nano infinity Nanotech)

15. FORMULATION OF NANOPARTICLES contd.
• FACE WASH - The skin is covered with a hydrolipid film that, depending on the area
of the body, comprises secretions from sebaceous glands and from apocrine and eccrine
sweat glands. Periodic cleansing to remove debris, dirt, and odor is essential to maintain
skin health.
• Silver nanoparticles are used as skin disinfectant and decontamination. Nano Cyclic
Inc. produces Nano Cyclic cleanser pink which is a scientifically balanced blend of
nanosilver and natural ingredients and claims that it kills harmful bacteria and fungi,
fights acne, and diminishes age spots and sun damaged skin.
Some Nano-based products –
 Nano Cyclic Cleanser Silver (Nano Cyclic)
 LifePak Nano (Pharmanex)

16. • Cosmetics are luxury articles, the usage of which has increased multi-fold in the
past few years.
• The Indian cosmetics market is currently worth $6.5 billion and is growing
exponentially.
• The research, production, quality control and sale of these products have been
augmenting steadily.
• Nanotechnology has proved, beyond doubt, its beneficial effects especially in
sunscreen products, skin care creams, lipsticks, toothpastes, hair cosmetics,
shaving preparations, shampoos, anti aging formulations in the past decade.

17. REFERENCES
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759978/.
• https://www.verywellhealth.com/what-are-nanoparticles-in-
sunscreen-4138307.
• https://sci-
hub.tw/https://www.sciencedirect.com/science/article/abs/pii/S0753
332218328713.
• https://www.slideshare.net/VishnuAmbareesh/nanodermatolgy-and-
nanocosmetics.