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BREAST
DR. SUDHIR KUMAR JAIN
M.B.B.S, M.S, M.B.A, FRCS, FACS, FICS
DIRECTOR PROFESSOR
DEPARTMENT OF SURGERY
MAULANA AZAD MEDICAL COLLEGE
ANATOMY
• Breast is a modified sebaceous gland lying between the subcutaneous areolar tissue
and the pectoral fascia
• Composed of branching system of ducts, ductules that end up in acini, that are the
chief milk producing glands.
• Acini join together to form lobules and lobes, that form the functional unit, termed
as lobular unit.
• Each lobe is drained by an individual collecting duct.
• Vertical: From 2nd – 6th ribs
• Horizontal: From side of
sternum to mid axillary line
• 2/3rd of tissue lies over the
pectoralis minor
• 1/3rd lies over the serratus
anterior
• Breast lies over the
subcutaneous tissue and
separated from the muscle
by deep fascia.
EXTENT
ANATOMY
AXILLARY TAIL OF SPENCE:
• Extension from the outer part of gland
• Reaches up to the 3rd rib in the axilla
• Lies under deep fascia
• Comes in direct contact with the axillary lymph nodes
ARCHITECTURE OF THE BREAST
• Acini Lobules Lobes
• Lobes are arranged in a radiating fashion like spokes of a wheel
• Converge onto the nipple
• Each lobe is drained by a collecting duct
• 10-15 collecting ducts
• Each duct drains a segmental system of smaller ducts and lobules
ARCHITECTURE
Lobule
Ductules
Subsegmental Duct
Segmental duct
Lactiferous sinus
Collecting Duct
• Large ducts are the sites of:
• Duct Papilloma
• Duct ectasia
• Distal ducts are the site of:
• Fibroadenoma
• Cyst formation
• Sclerosing adenosis
ARTERIAL SUPPLY
• 3 major vessels
• Lateral Thoracic artery (br. of 2nd part of axillary artery)
• Perforating branches of internal mammary artery via 2nd, 3rd, 4th spaces
• Lateral branches of 2md, 3rd, 4th intercostal arteries
ARTERIAL SUPPLY
VENOUS DRAINAGE
• 3 major veins
• Axillary vein
• Internal Mammary Vein
• Intercostal Veins
VENOUS DRAINAGE
LYMPHATIC DRAINAGE
1
2 set of lymphatics
2
1. Lymphatics of the skin
over the breast except
nipple and areola
3
2. Lymphatics of the
parenchyma of the breast
with nipple and areola
LYMPHATIC DRAINAGE
• Lymphatics of the skin (Except nipple and areola)
• Pass in radial direction
• End in surrounding nodes
• From outer side- Axillary nodes
• From upper part- Supraclavicular nodes
• From Inner part- Internal mammary nodes
• Lymphatics of nipple and areola Subareolar plexus of Sappy Communicates
with the lymphatics of breast tissue
LYMPHATIC DRAINAGE
• Lymphatics of breast parenchyma
• 75%- Axillary lymph nodes
• 25%-medial and lateral part of breast Internal mammary nodes
• Axillary lymph nodes are arranged in 5 sets:
• Anterior- along lateral thoracic veins
• Posterior- along subscapular vessels
• Lateral- along axillary vein
• Central- along Intercostobrachial
• Apical- known as infraclavicular lymph nodes
INVESTIGATIONS
MAMMOGRAPHY
• Soft tissue x-ray of breast
• Low voltage, high amperage x-rays
• Dose-0.1 rad
• 2 views- a) Cranio-caudal (CC) b) Medio-lateral oblique (MLO)
MAMMOGRAPHY
MAMMOGRAPHY
• Uses:
• Breast screening to detect carcinoma breast at an early stage.
• To detect tumors which are not clinically palpable (<0.5cm)
• For evaluation of opposite breast in proven cases of carcinoma of one breast
• Follow up cases of carcinoma breast after treatment.
ULTRASONOGRAPHY
• Useful in young women
• To distinguish solid from cystic lesions
• To detect impalpable breast lumps
ULTRASONOGRAPHY
Cystic lesion appearing
as oval, well
circumscribed
hyperechoic lesion
Solid lesion
appearing as
irregular,
hyperechoic
lesion
MRI
• Uses:
• To distinguish scar from recurrence in patients who have previous breast
conservation surgery for breast cancer.
• For imaging breasts of patients with implants.
• Screening tool in high risk breast cancer patients.
• Management of axilla in both primary breast cancer as well as recurrent
diseases.
• Paget’s disease of the nipple without radiographic evidence of primary tumour.
MRI
MRI
• Routine screening of patients with MRI is recommended for the following:
• Known BRCA1 or BRCA 2 gene mutation.
• First degree relative with known BRCA1 or BRCA 2 gene mutation
• Radiation therapy to the chest between the ages 10 and 30
• Li fraumeni or Cowden syndormes or a first degree elative with one of these
syndromes.
BIOPSY OF BREAST LESIONS
BIOPSY
• FNAC
• Trucut Biopsy
• Excisional/Incisional Biopsy
FNAC
• Using a 22 gauge needle and 10ml syringe
• Multiple passes are made through the lesion
• Fluid and cellular material is air dried and fixed on a slide
• Investigation of choice for tissue diagnosis in cases of breast lumps
• Use is limited in suspected cases of malignancy, as it cannot differentiate invasive
from non-invasive carcinoma
FNAC
TRUCUT BIOPSY
• Method of choice for obtaining tissue diagnosis in breast lesions
• May be performed under USG, MRI, mammographic guidance or clinically
• Helps in differentiating benign invasive from non-invasive cancers
• Helps in determining histological subtype, grade, receptor status of the tumour
TRUCUT BIOPSY
EXCISIONAL BIOPSY
• Use is limited since the advent of trucut biopsy
• Reserved for cases where the histological results obtained via trucut biopsy are
discordant with the radiological results
TRIPLE
ASSESEMENT
• For any breast lump
diagnosis is achieved via
a combination of clinica,
radiological and tissue
diagnosis
NIPPLE DISCHARGE
Physiological- following
pregnancy, lactation
01
Pathological
02
Nipple discharge
Milky
(Lactation, Galactocoele)
Blood
(Duct carcinoma, Duct
papilloma, Duct ectasia,
Pagets disease,
Fibroadenosis
Non milky
Serous
E.g Early
pregnancy
Thick Creamy
E.g Duct Ectasia
Purulent (Yellow)
E.g Breast Abscess
Various shades (brown,
green, black)
Fiboadenosis, duct
ectasia
MANAGEMENT OF NIPPLE DISCHARGE
BREAST ABSCESS
• According to severity of onset:
• Acute
• Subacute
• Chronic
BREAST ABSCESS
• According to their position:
• Pre-mammary- Subareolar
• Intra-mammary
• Retro-mammary
• Acute Intra-mammary is the most common type. Accounts for 85% of breast abscess
cases
ETIOLOGY
• >90% occur in lactating women
• Most common during 1st month lactation
• Most common organism is Staphylococcus aureus
• Source is Infants throat
CLINICAL FEATURES
• I- STAGE OF CELLULITIS
 Swollen, congested and painful, fever+
• II-STAGE OF LOCALISATION AND ASBCESS FORMATION
 Tissue necrosis and abscess spreads to adjacent tissues. Fluctuation+.
Overlying skin oedematous and indurated
BREAST ABSCESS
Breast
Abscess- USG
image
Breast Abscess-
Gross overlying
skin
erythematous,
oedematous,
tender
TREATMENT
• Stage of Cellulitis:
• Conservative- Analgesics, local heat
• Antibiotics-Cloxacillin or Erythromycin
• Infected breast should be emptied of milk using breast pump
• Stage of Abscess formation:
• Incision and Draiange of thee abscess
• Supportive Antibiotics
THANK YOU

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Breast anatomy, investigations and benign conditions

  • 1. BREAST DR. SUDHIR KUMAR JAIN M.B.B.S, M.S, M.B.A, FRCS, FACS, FICS DIRECTOR PROFESSOR DEPARTMENT OF SURGERY MAULANA AZAD MEDICAL COLLEGE
  • 2. ANATOMY • Breast is a modified sebaceous gland lying between the subcutaneous areolar tissue and the pectoral fascia • Composed of branching system of ducts, ductules that end up in acini, that are the chief milk producing glands. • Acini join together to form lobules and lobes, that form the functional unit, termed as lobular unit. • Each lobe is drained by an individual collecting duct.
  • 3. • Vertical: From 2nd – 6th ribs • Horizontal: From side of sternum to mid axillary line • 2/3rd of tissue lies over the pectoralis minor • 1/3rd lies over the serratus anterior • Breast lies over the subcutaneous tissue and separated from the muscle by deep fascia. EXTENT
  • 4. ANATOMY AXILLARY TAIL OF SPENCE: • Extension from the outer part of gland • Reaches up to the 3rd rib in the axilla • Lies under deep fascia • Comes in direct contact with the axillary lymph nodes
  • 5. ARCHITECTURE OF THE BREAST • Acini Lobules Lobes • Lobes are arranged in a radiating fashion like spokes of a wheel • Converge onto the nipple • Each lobe is drained by a collecting duct • 10-15 collecting ducts • Each duct drains a segmental system of smaller ducts and lobules
  • 6.
  • 8.
  • 9. • Large ducts are the sites of: • Duct Papilloma • Duct ectasia • Distal ducts are the site of: • Fibroadenoma • Cyst formation • Sclerosing adenosis
  • 10.
  • 11. ARTERIAL SUPPLY • 3 major vessels • Lateral Thoracic artery (br. of 2nd part of axillary artery) • Perforating branches of internal mammary artery via 2nd, 3rd, 4th spaces • Lateral branches of 2md, 3rd, 4th intercostal arteries
  • 13. VENOUS DRAINAGE • 3 major veins • Axillary vein • Internal Mammary Vein • Intercostal Veins
  • 15. LYMPHATIC DRAINAGE 1 2 set of lymphatics 2 1. Lymphatics of the skin over the breast except nipple and areola 3 2. Lymphatics of the parenchyma of the breast with nipple and areola
  • 16. LYMPHATIC DRAINAGE • Lymphatics of the skin (Except nipple and areola) • Pass in radial direction • End in surrounding nodes • From outer side- Axillary nodes • From upper part- Supraclavicular nodes • From Inner part- Internal mammary nodes • Lymphatics of nipple and areola Subareolar plexus of Sappy Communicates with the lymphatics of breast tissue
  • 17. LYMPHATIC DRAINAGE • Lymphatics of breast parenchyma • 75%- Axillary lymph nodes • 25%-medial and lateral part of breast Internal mammary nodes
  • 18. • Axillary lymph nodes are arranged in 5 sets: • Anterior- along lateral thoracic veins • Posterior- along subscapular vessels • Lateral- along axillary vein • Central- along Intercostobrachial • Apical- known as infraclavicular lymph nodes
  • 19.
  • 21. MAMMOGRAPHY • Soft tissue x-ray of breast • Low voltage, high amperage x-rays • Dose-0.1 rad • 2 views- a) Cranio-caudal (CC) b) Medio-lateral oblique (MLO)
  • 23. MAMMOGRAPHY • Uses: • Breast screening to detect carcinoma breast at an early stage. • To detect tumors which are not clinically palpable (<0.5cm) • For evaluation of opposite breast in proven cases of carcinoma of one breast • Follow up cases of carcinoma breast after treatment.
  • 24. ULTRASONOGRAPHY • Useful in young women • To distinguish solid from cystic lesions • To detect impalpable breast lumps
  • 25. ULTRASONOGRAPHY Cystic lesion appearing as oval, well circumscribed hyperechoic lesion Solid lesion appearing as irregular, hyperechoic lesion
  • 26. MRI • Uses: • To distinguish scar from recurrence in patients who have previous breast conservation surgery for breast cancer. • For imaging breasts of patients with implants. • Screening tool in high risk breast cancer patients. • Management of axilla in both primary breast cancer as well as recurrent diseases. • Paget’s disease of the nipple without radiographic evidence of primary tumour.
  • 27. MRI
  • 28. MRI • Routine screening of patients with MRI is recommended for the following: • Known BRCA1 or BRCA 2 gene mutation. • First degree relative with known BRCA1 or BRCA 2 gene mutation • Radiation therapy to the chest between the ages 10 and 30 • Li fraumeni or Cowden syndormes or a first degree elative with one of these syndromes.
  • 29. BIOPSY OF BREAST LESIONS
  • 30. BIOPSY • FNAC • Trucut Biopsy • Excisional/Incisional Biopsy
  • 31. FNAC • Using a 22 gauge needle and 10ml syringe • Multiple passes are made through the lesion • Fluid and cellular material is air dried and fixed on a slide • Investigation of choice for tissue diagnosis in cases of breast lumps • Use is limited in suspected cases of malignancy, as it cannot differentiate invasive from non-invasive carcinoma
  • 32. FNAC
  • 33. TRUCUT BIOPSY • Method of choice for obtaining tissue diagnosis in breast lesions • May be performed under USG, MRI, mammographic guidance or clinically • Helps in differentiating benign invasive from non-invasive cancers • Helps in determining histological subtype, grade, receptor status of the tumour
  • 35. EXCISIONAL BIOPSY • Use is limited since the advent of trucut biopsy • Reserved for cases where the histological results obtained via trucut biopsy are discordant with the radiological results
  • 36. TRIPLE ASSESEMENT • For any breast lump diagnosis is achieved via a combination of clinica, radiological and tissue diagnosis
  • 38. Nipple discharge Milky (Lactation, Galactocoele) Blood (Duct carcinoma, Duct papilloma, Duct ectasia, Pagets disease, Fibroadenosis Non milky Serous E.g Early pregnancy Thick Creamy E.g Duct Ectasia Purulent (Yellow) E.g Breast Abscess Various shades (brown, green, black) Fiboadenosis, duct ectasia
  • 39. MANAGEMENT OF NIPPLE DISCHARGE
  • 40.
  • 41. BREAST ABSCESS • According to severity of onset: • Acute • Subacute • Chronic
  • 42. BREAST ABSCESS • According to their position: • Pre-mammary- Subareolar • Intra-mammary • Retro-mammary • Acute Intra-mammary is the most common type. Accounts for 85% of breast abscess cases
  • 43. ETIOLOGY • >90% occur in lactating women • Most common during 1st month lactation • Most common organism is Staphylococcus aureus • Source is Infants throat
  • 44. CLINICAL FEATURES • I- STAGE OF CELLULITIS  Swollen, congested and painful, fever+ • II-STAGE OF LOCALISATION AND ASBCESS FORMATION  Tissue necrosis and abscess spreads to adjacent tissues. Fluctuation+. Overlying skin oedematous and indurated
  • 45. BREAST ABSCESS Breast Abscess- USG image Breast Abscess- Gross overlying skin erythematous, oedematous, tender
  • 46. TREATMENT • Stage of Cellulitis: • Conservative- Analgesics, local heat • Antibiotics-Cloxacillin or Erythromycin • Infected breast should be emptied of milk using breast pump • Stage of Abscess formation: • Incision and Draiange of thee abscess • Supportive Antibiotics
  • 47.