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Permethrin is a medication and insecticide used to treat scabies and lice. As a medication, it is applied topically as a cream or lotion to kill the parasites. As an insecticide, it can be sprayed on clothing and nets. It works by acting on the nervous system of insects and parasites, causing muscle spasms and paralysis. It is used to treat conditions like scabies, pubic lice, head lice, and crusted scabies. When applied topically, it is poorly absorbed and any amount absorbed is rapidly metabolized and excreted in urine. Common side effects include skin rash and redness. It is generally safe in pregnancy.
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Scabies is caused by tiny burrowing mites that infest the skin and lay eggs, causing intense itching. It spreads through direct, prolonged skin-to-skin contact. The mites burrow beneath the skin and lay eggs, triggering an allergic reaction and itching. Symptoms include itching and thin burrow tracks on the skin. Doctors diagnose scabies by examining the skin for mites or eggs under a microscope. Treatment involves applying prescription creams or lotions to kill the mites. Close contacts may also need treatment to prevent reinfestation.
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Scabies (also known as the seven-year itch) is a contagious skin infestation by the mite Sarcoptes scabiei. The most common symptoms are severe itchiness and a pimple-like rash. Occasionally, tiny burrows may appear on the skin. In a first-ever infection, the infected person usually develops
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The document describes several anatomical spaces and structures. It begins by describing the axilla region, including its borders and contents such as nerves, vessels and lymph nodes. It then discusses the cubital fossa and its clinical relevance for measuring blood pressure and performing venepuncture. Finally, it examines the carpal tunnel and its importance in carpal tunnel syndrome, as well as the anatomical snuffbox and its relationship to scaphoid fractures.
CVS lssn 2.pptx
Cardiac failure, also known as heart failure, results from any structural or functional disorder that impairs the heart's ability to fill with or eject blood. The causes include pump failure, pressure overload, volume overload, and multifactorial causes. The main types are left ventricular failure, right ventricular failure, and chronic heart failure. Signs and symptoms include dyspnea, orthopnea, edema, and fatigue. Diagnosis involves physical exam, chest x-ray, electrocardiogram, and echocardiogram.
antihistamine presentation-khall.ppt
Antihistamines are drugs that reduce or eliminate the effects of histamine, which is released during allergic reactions. There are several classes of antihistamines including first generation, second generation, and third generation. First generation antihistamines are effective but cause more side effects like sedation due to their ability to cross the blood brain barrier. Newer generations have been developed with greater selectivity for peripheral histamine receptors, resulting in fewer side effects. Research continues on developing more selective antihistamines and exploring the anti-inflammatory properties and potential for new treatments.
Lecture 4(0).pdf
This document provides an overview of the peripheral nervous system, with a focus on receptors, sensation, pain, vision, and hearing. It discusses:
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3) Characteristics of pain, including nociceptors and pain neurotransmitters.
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Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
Levelling: Instrument used Object of levelling, Methods of levelling in brief, and Contour maps.
Chapter 4
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Chapter 6
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Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
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- 1. Mishi Soza Mlongo 🖤🍁 Group 4
- 4. Trade name; • Nix • Rid • Elimite • Acticin
- 5. Introduction; • Is a medication and an insecticide. -As a medication it is used to treat scabies & lives by applying it on skin as a cream or lotion. -While as insecticide it can be sprayed onto clothing or mosquito nets to kill the insects that touch them. • It was discovered in 1973 being one of the WHO list of essential medicines.
- 6. Pharmacodynamics; M.O.A • Permethrin, a pyrethroid,is active against a broad range of pests.. lice, Fleas,Mites,Ticks and Other arthropods (M.O.A) -Act on the nervous system of insects. -By acting on the nerves cell membrane interfering with sodium channel disrupt the function of neurons and cause muscle spasms leading to paralysis and death of pests. @@@kill the pests and eggs.
- 7. Indication; • Pediculosis pubis# pubis lice #crabs#Pthirus pubis. • Sarcoptes scabiei# itching mites{scabies} • Norwegian scabiei#crusted scabiei • Head lice#Pediculus humanus capitis.
- 8. Cont’;
- 9. Infestation; @In adults and older children Occur in ; • On chest • Around nipples • On soles of feet • On inner elbow • Along the inside the wrist • Around waist • In armpit • Between fingers and toes
- 10. Contraindications; • Child younger than 2months age . • Hypersensitivity. NB# • Permethrin has a greater evidence of safety in pregnancy.
- 11. Kinetic; • Administered topically. • Can also be (inhale, ingested) .. • Absorption:- poorly absorbed through skin(as it is locally administered ) • Metabolism:- rapid metabolized by ester hydrolysis to inactive metabolites which are excreted primarily in urine.
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