This document discusses bio-insecticides, which are organic formulations used to control insects that damage crops. Bio-insecticides use microorganisms or their toxins, including bacteria, viruses, fungi, protozoa, and nematodes. These organisms act as natural insecticides by producing toxins or by infecting and killing insects. The document categorizes different types of bio-insecticides and provides examples and modes of action for each type. It also outlines advantages like specificity and safety compared to chemical pesticides, as well as disadvantages like slower action and susceptibility to environmental factors.