This document provides information on breast oncoplastic surgery techniques:
- Oncoplastic surgery (OPS) integrates plastic surgery with breast-conserving cancer surgery to allow for wider excisions without compromising breast shape. It ranges from simple reshaping to advanced mammoplasty techniques.
- Key factors in determining the appropriate OPS approach are excision volume, tumor location, breast density, and glandular composition. Excisions over 20% of breast volume or from certain locations risk deformity. OPS allows excision of up to 1000g compared to 80g for standard surgery.
- OPS techniques are classified into Level I involving reshaping and Level II involving skin excision and reshaping using
Oncoplastic Breast surgery is simultaneous application of lumpectomy and reconstructive techniques. The word ‘oncoplastic’ is derived from the Greek words ‘onco’ (tumour) and ‘plastic’ (to mould).
Approximately 10% to 30% of patients submitted to BCS alone are not satisfied with the aesthetic outcomes like “swan beak/ parrot beak deformities. The main reasons are related this is the tumour resection which can produce asymmetry, retraction, and volume changes in the breast.
Recently, increasing attention has been focused on oncoplastic procedures since the immediate application of plastic breast surgery techniques provide a wider local excision while still achieving the goals of a better breast shape and symmetry to obtain oncologically sound and aesthetically pleasing results. Thus, by means of customized techniques the surgeon ensures that oncologic principles are not jeopardized while meeting the needs of the patient from an aesthetic point of view.
Oncoplastic Breast surgery is simultaneous application of lumpectomy and reconstructive techniques. The word ‘oncoplastic’ is derived from the Greek words ‘onco’ (tumour) and ‘plastic’ (to mould).
Approximately 10% to 30% of patients submitted to BCS alone are not satisfied with the aesthetic outcomes like “swan beak/ parrot beak deformities. The main reasons are related this is the tumour resection which can produce asymmetry, retraction, and volume changes in the breast.
Recently, increasing attention has been focused on oncoplastic procedures since the immediate application of plastic breast surgery techniques provide a wider local excision while still achieving the goals of a better breast shape and symmetry to obtain oncologically sound and aesthetically pleasing results. Thus, by means of customized techniques the surgeon ensures that oncologic principles are not jeopardized while meeting the needs of the patient from an aesthetic point of view.
Component seperation technique for the repair of very large ventral hernias nikhilameerchetty
Includes all the ventral hernia repairs with the loss of domain and the various methods of component separation technique with their success rate for their repair ,few videos showing the methods of repair in addition to the latest techniques of repair .
In this presentation, I have shown how to do open anterior resection both high and low varieties in a step-by-step manner with clear pictures as if reading an atlas of operative surgery.
Breast Conservation Surgery is defined as the complete removal of the tumour with a concentric margin of surrounding healthy tissue with maintenance of acceptable cosmesis, and should be followed by radiation therapy to achieve an acceptably low rate of local recurrence. Breast conservation treatment is BCS with radiotherapy.
Minimal invasive Surgery in Management of colorectal cancerpiyushpatwa
Laparoscopic Anterior resection. After insertion of ports with patient in steep trendelenburg position Inferior mesenteric artery was identified and high ligation done with division of left colic artery and then medial to lateral dissection was done. Subsequently inferior mesenteric vein was dissected and clipped and divided. Distal dissection proceeded just behind the superior rectal artery and after identification and preservation of the hypogastric nerves, upper rectum was mobilised. Division of bowel was done at upper rectum after giving adequate distal margin and end to end anastomosis was done using circular stapler.
Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface MalignanciesMary Ondinee Manalo Igot
The prognosis of most peritoneal surface malignancies were previously dismal. However, with the incorporation of HIPEC to standard of care, we have been seeing doubling of survival for select malignancies. Appropriate patient selection is crucial.
In Depth review of the Surgical management of esophageal carcinoma including management overview, endoscopic management, Type of surgeries, Open, and minimally invasive, Extent of lymphadenectomy. Literature review of evidence for type of surgery and complications
This is a paper which describes an innovative approach for skin sparing mastectomy. This incision tends to distract the eye and be less noticeable. Additionally it allows excellent access to the axilla for lymph node sampling and reduces the excessive retraction on the skin flaps.
Component seperation technique for the repair of very large ventral hernias nikhilameerchetty
Includes all the ventral hernia repairs with the loss of domain and the various methods of component separation technique with their success rate for their repair ,few videos showing the methods of repair in addition to the latest techniques of repair .
In this presentation, I have shown how to do open anterior resection both high and low varieties in a step-by-step manner with clear pictures as if reading an atlas of operative surgery.
Breast Conservation Surgery is defined as the complete removal of the tumour with a concentric margin of surrounding healthy tissue with maintenance of acceptable cosmesis, and should be followed by radiation therapy to achieve an acceptably low rate of local recurrence. Breast conservation treatment is BCS with radiotherapy.
Minimal invasive Surgery in Management of colorectal cancerpiyushpatwa
Laparoscopic Anterior resection. After insertion of ports with patient in steep trendelenburg position Inferior mesenteric artery was identified and high ligation done with division of left colic artery and then medial to lateral dissection was done. Subsequently inferior mesenteric vein was dissected and clipped and divided. Distal dissection proceeded just behind the superior rectal artery and after identification and preservation of the hypogastric nerves, upper rectum was mobilised. Division of bowel was done at upper rectum after giving adequate distal margin and end to end anastomosis was done using circular stapler.
Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface MalignanciesMary Ondinee Manalo Igot
The prognosis of most peritoneal surface malignancies were previously dismal. However, with the incorporation of HIPEC to standard of care, we have been seeing doubling of survival for select malignancies. Appropriate patient selection is crucial.
In Depth review of the Surgical management of esophageal carcinoma including management overview, endoscopic management, Type of surgeries, Open, and minimally invasive, Extent of lymphadenectomy. Literature review of evidence for type of surgery and complications
This is a paper which describes an innovative approach for skin sparing mastectomy. This incision tends to distract the eye and be less noticeable. Additionally it allows excellent access to the axilla for lymph node sampling and reduces the excessive retraction on the skin flaps.
this slide contain detail about chest wall tumor, its classification, presentation and management. This also contain chest wall reconstruction and way of reconstruction.
Introduction to mammography and its equipment.
Different views on mammography & supplementary views.
Birads mammographic lexicon
Birads ultrasound lexicon
Imaging of suspicious mammary lymph nodes
Categories in BIRADS 2013.
SurgiSculpt Offers the Most Excellent Gynecomastia Treatment.docxSurgiSculpt
You desire one of SurgiSculpt's top-notch gynecomastias in the country. Gynecomastia surgery, which involves various body modification treatments, is something we provide. Please visit our official site for further information if you require it.
Accelerated partial breast irradiation is an alternative to whole breast irradiation in carcinoma breast patients Post breast conserving surgery with equivalent outcome, less duration & less burden on the patient.
Comprehensive review of Isolated Axillary lymph nodal metastasis of unknown origin- Clinically unknown primary axilla which includes detailed approach and management of inguinal lymph nodal metastasis also
Neoadjuvant Chemoradiation in Borderline resectable pancreatic adenocarcinomaDr.Bhavin Vadodariya
Comprehensive review of evidence in Neoadjuvant Chemoradiation in Borderline resectable pancreatic adenocarcinoma which includes classification of pancreatic cancer.
Detailed Information regarding MSKCC,IMDC score with evidence .
SSIGN Score, Fuhrman's grading described .
Prognostic significance of risk score explained
The Trial Assigning IndividuaLized Options for Treatment (Rx) -TAILORx,TAILORx clinical trial showed that most women with hormone receptor (HR)–positive, HER2-negative, axillary node–negative early-stage breast cancer and a mid-range score on a 21-tumor gene expression assay (Oncotype DX® Breast Recurrence Score) do not need chemotherapy after surgery
Brief Review of Surgical management of Early laryngeal cancer e.g glottic and supraglottic cancer.
This presentation describes latest literature evidence of conservative laryngeal surgery as well as radiotherapy in early glottic cancer
Ca ovary staging(AJCC 8th Edition& FIGO 2014) and classificationDr.Bhavin Vadodariya
Pathological classification of ovary in details.
Principles of Staging in Ca Ovary.
Staging according to AJCC 8th edition & Figo 2014.
Summary of changes in 8th Edition AJCC
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
2. Definition
Oncoplastic surgery (OPS) has emerged as a new
approach to allow wide excision for BCS without
compromising the natural shape of the breast.
It is based upon integration of plastic surgery techniques for
immediate breast reshaping after wide excision for breast
cancer.
3. Oncoplastic techniques for breast conservation range from
simple reshaping and mobilization of breast tissue to more
advanced mammoplasty techniques that allow resection of
up to 50% of the breast volume.
5. Excision Volume
Single most predictive factor of surgical outcome and potential for
breast deformity.
Studies have suggested that, once 20% of the breast volume is
excised, there is a clear risk of deformity.
Excision volume compared to the total breast volume is estimated
preoperatively.
Through systematic determination of specimen weights, accurate
preoperative estimation of excision volume can be achieved.
Bulstrode NW, Shortri S. Prediction of cosmetic outcome following conservative breast surgery using breast volume
measurements. Breast. 2001;10:124–6.
6. Excision Volume(contd.)
The average specimen from BCS weighs 20–40 g; as a
general rule 80 g of breast tissue is the maximum weight
that can be removed from a medium-sized breast without
resulting in deformity.
7. Excision Volume(contd.)
OPS techniques allow for significantly greater excision
volumes while preserving natural breast shape.
All OPS studies have demonstrated that an average of 200
g up to 1000 g or more can be removed from a medium to
large sized breast during BCS with no cosmetic
compromise
Kaur N, Petit JY, Rietjens M, et al. Comparative study of surgical margins in oncoplastic surgery and
quadrantectomy in breast cancer. Ann Surg Oncol. 2005;12(7):539–45.
8. Volume displacement
Reshaping of the breast is based upon the rearrangement
of breast parenchyma to create a homogenous
redistribution of volume loss.
This redistribution can be achieved easily though either
advancement or rotation of breast tissue into the
lumpectomy cavity
9. Volume Replacement technique
The harvesting of a latissimus dorsi ‘‘miniflap’’ to fill in the
defect.
This volume replacement technique has been recently
described by Rainsbury.
In general, this approach is reserved for small-sized
breasts.
Rainsbury R. Surgery insight: oncoplastic breast-conserving reconstruction-indications,
benefits, choices and outcomes. Nat Clin Pract Oncol. 2007;4(11):657–64.
10. Tumour Location
The key too used in planning the appropriate surgical
approach is evaluating the tumor location and the
associated risk of deformity.
11. Favourable
The upper outer quadrant of the breast is a favorable
location for large-volume excisions.
In this location, defects can readily be corrected by
mobilization of adjacent tissue.
12. Unfavourable
Excision from less favorable locations, such as the lower
pole or upper inner quadrants of the breast, often creates a
major risk for deformity.
For example, a ‘‘bird’s beak’’ deformity is classically seen
on excision of tumors from the lower pole of the breast
13. Glandular density
It is evaluated both clinically and radiographically.
Although the clinical exam is reliable, mammographic
evaluation is a more reproducible approach for breast
density determination.
Breast density predicts the fatty composition of the breast
and determines the ability to perform extensive breast
undermining and reshaping without complications.
14. Breast density can be classified into four categories based
on the Breast Imaging Reporting and Data System
(BIRADS):
• a-Fatty
• b- Scattered fibroglandular
• c-Heterogeneously dense
• d-Extremely dense breast tissue
15. Undermining the breast from both the skin and pectoralis
muscle (dual-plane undermining) is a major requirement to
perform level I OPS.
A dense glandular breast (BIRADS 3/4) can easily be
mobilized by dual-plane undermining without risk of
necrosis.
16. Low-density breast tissue with a major fatty composition
(BIRADS 1/2) has a higher risk of fat necrosis after
extensive undermining.
Low breast density should provoke the decision to either
limit the amount of undermining during level I OPS or
proceed to a level II OPS that requires only posterior
undermining, leaving the skin attached
18. Type 1 Oncoplasty
Based on dual plane undermining including Nipple areola
complex (NAC) and NAC recentralization if nipple deviation
is anticipated.
No skin excision is requires
19. Type 2 Oncoplasty
It allows major volume resection.
They encompass more complex procedures derived from
breast reduction techniques.
These ‘‘therapeutic mammoplasties’’ involve extensive skin
excision and breast reshaping.
They result in a significantly smaller, rounder breast.
22. OPS may result in longer and multiple scars.
The patient should be aware of the possible asymmetry
caused by level II OPS.
Because of the extensive resection, an asymmetry in
volume is expected compared with the contralateral breast.
This asymmetry may require immediate symmetrization of
the contralateral side if desired by the patient, or can be
performed as a second-stage procedure.
23. All oncoplastic procedures begin with the preoperative
marking of the patient sitting in the upright position prior to
induction of anesthesia.
Once marked, both breasts are draped into the operative
field for comparison.
The patient is centered on the operating room table to
accommodate both the supine and upright position, as she
will be transitioned between these positions to allow optimal
reshaping and symmetry.
24. The patient is then secured into place with either arms
extended, for access to the axilla, or both arms at the sides
if no axillary surgery is needed.
27. 1. Extensive Skin undermining
2. Dual plane undermining and excision
of tumor
3. Glandular Repositioning
28.
29. Incision
Oncoplastic surgery is based upon allowing wide excisions
with free margins, not on minimizing incision length.
Short incisions limit mobilization of the gland and do not
permit creation of adequate glandular flaps to fill in excision
defects.
This effective mobilization of the gland is a key component
of breast reshaping after wide excisions.
30. Incision
The location of the incision is at the discretion of the
operating surgeon.
All incisions should allow for both en bloc excision of the
cancer, without causing fragmentation of the specimen, and
extensive undermining to facilitate reshaping.
31. Incision
For level I procedures, if a direct incision over he tumor is
chosen, the general principle is to follow Kraissl’s lines of
tension to limit visible scaring.
However, in many cases an indirect incision along the
areola border is possible and can be extended by a radial
extension towards the tumor.
32. Skin undermining
Easier before excising the lesion.
Follows the mastectomy plane and extends anywhere from
one-fourth to two-thirds of the surface area of the breast
envelope.
Facilitates both tumor resection and glandular redistribution
after removal of the tumor.
Less undermining- smoking, fatty breast
33. NAC Undermining
Extensive resections lead to NAC deviation towards the
excision area.
NAC repositioning is easily performed with simple
undermining.
This is a key component of both level I and II OPS.
The first step is to completely transect the terminal ducts
and separate the NAC from the underlying breast tissue.
34. NAC undermining
A width of 0.5–1 cm of attached glandular tissue is
maintained to ensure the integrity of the vascular supply.
This appropriate amount of sub areolar tissue prevents
NAC necrosis and avoids venous congestion.
Ultimately, the level of NAC sensitivity may be reduced after
extensive mobilization and undermining
35. Glandular Resection
Clough’s standard approach is to perform full-thickness
excisions from the subcutaneous fat underlying the skin
down to the pectoralis fascia.
A full-thickness excision ensures free anterior and posterior
margins, leaving only the lateral margins in question.
36. Glandular Resection
The breast parenchyma itself is excised in a fusiform pattern
oriented towards the NAC.
This shape facilitates reapproximation of the remaining gland.
Before closing the defect, metal clips are placed on the pectoralis
muscle and lateral edges of the resection bed to guide future
radiotherapy.
37. Defect Closure
Extensive resections require closing the cavity and
redistribution of the volume loss.
Tissue can be mobilized from lateral positions of the
remaining gland or recruited from the central portion of the
breast.
This allows creation of glandular flaps that are sutured
together to close the defect.
38. NAC Repositioning
Avoiding NAC displacement is a key element for both levels I and
II OPS.
An unnatural position of the NAC deviated towards the excision
site can be one of the major sources of patient dissatisfaction
after BCS.
This result should be expected after all extensive volume
resections.
39. NAC Repositioning
NAC repositioning is difficult to attempt after radiotherapy;
therefore, immediate recentralization is preferred and
shouldbe anticipated during initial resection.
An area of periareolar skin opposite the excision defect is
deepithelialized in the shape of a crescent. For level I
procedures, the width of deepithelialization can measure up
to 6 cm.
40. NAC Repositioning
Deepithelization should be achieved sharply, using a
scalpel blade or fine scissors. This technique is simple and
safe, and is used systematically in aesthetic surgery of the
breast.
The vascular supply of the NAC after its separation from
the gland and deepithelialization is based on the dermal
vasculature
43. Principles
Reserved for situations that require major volume excisions
of 20–50%.
The superior pedicle reduction mammoplasty will serve as
a model for the technical description of all mammoplasty
techniques.
Rotating the NAC pedicle opposite the site of tumor
excision allows the application of this technique for a variety
of tumor locations.
44. Principles
Because of the volume excised, level II OPS will generally
result in a breast that is smaller, rounder, and higher
contralateral symmetrization should be discussed in the
preoperative setting.
Either immediate or delayed symmetrization can be
performed depending on the amount of tissue resection