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ASTHMA
Department of Medical
Surgical Nursing
1
LEARNING OBJECTIVES
At the end of this lecture the students should be able to:-
Define asthma.
Enumerate the causes of asthma.
Explain about the pathophysiology of asthma.
List out the clinical manifestations of asthma.
Enumerate the diagnostic evaluation of asthma.
Explain the management of asthma. 2
Introduction
• Asthma is a condition in which airways narrow
and swell and may produce extra mucus. This
can make breathing difficult and trigger
coughing, a whistling sound (wheezing) when
breathe out and shortness of breath.
3
DEFINITION
Asthma:---It is a chronic inflammatory disease of
airway in which inflammation causes varying
degree of obstruction in the airway.
4
5
INCIDENCE
• Asthma affect an estimated 20 million
Americans.
• Among adults, women have 30 % greater
prevalence of asthma than men.
• 39% higher in African Americans than in whites.
• 4000 deaths per year.
6
CLASSIFICATION OF ASTHMA
ASTHMA
Step 1
Mild intermittent
Step 2
Mild persistent
Step 3
Moderate persistent.
Step 4
Severe persistent.
7
8
1. Exact cause unknown.
2. Triggers:-
Allergens- IgE receptors mast cells.
Exercise induced asthma.
Respiratory infections.
CAUSES OF ASTHMA
9
Nose & sinus problems.
 Allergic Rhinitis.
 Nasal polyps.
 Sinusitis.
 Smoking
Ct--CAUSES OF ASTHAMA
10
• Drugs & food additives.
• Gastro esophageal reflux disease
(GERD).
• Emotional stress.
• Genetic factors.
• Bugs in house , pollen
Ct--CAUSES OF ASTHMA
11
Release of mediators from the mast cells like eosinophils,
basophils, macrophages, lymphocytes.
Early phase response
(with in 30 – 60 min)
Late phase response
(with in 5 – 6 hours).
IgE mast cells mediated response
Triggers
PATHOPHYSIOLOGY
12
•Bronchial smooth muscle
constriction.
•Excessive mucus secretion.
•Vascular leakage.
•Mucosal edema.
•Infiltration by eosinophils, basophils,
neutrophils.
•Inflammation.
•Bronchial hyperactivity.
•Infiltration with monocytes,
lymphocytes.
•Obstruction of large & small airways.
• Air trapping
•Respiratory acidosis
•hypoxemia 13
1. Wheezing, fever.
2. Dyspneoa, chest pain.
3. Cough with sputum.
4. Prolonged expiration.
5. Signs & symptoms of hypoxemia.
CLINICAL MANIFESTATIONS
14
7. Restlessness & increased anxiety.
8. Increased pulse & B.P.
9. Pulsus paradoxus.
10.Tachypnea.
11.Absence of normal breath sounds.
Ct---CLINICAL MANIFESTATIONS
15
1. History taking.
2. Physical examination.
3. Pulmonary function test.
4. Chest x- ray.
5. Peak flow monitoring.
6. Blood studies.
7. Sputum culture sensitive
examination.
DIAGNOSTIC EVALUATION
16
Medical management:
1. Anti inflammatory drugs:--
i. Corticosteroids
ii. Chronolyn sodium, nedochronil (for
children).
iii. Lucoterine modifiers, e.g. zafirlucast,
zeileuton, montelucast.
2. Bronchodilators:--
e.g. β- adrenergic agents, methylxanthine
preparations, anticholinergic agents.
TREATMENT
17
Ct---TREATMENT
3. Mast cell stabilizers.
4. Anti IgE antibody.
5. Β2 sympathomimetics.
18
• Pneumothorax.
• Rib fracture.
• Atelectasis.
• Pneumonia.
• Pneumomediastinum.
• Status asthmaticus.
COMPLICATIONS
19
NURSING MANAGEMENT
Nursing diagnosis.
i. Ineffective breathing pattern related to disease
condition.
ii. Impaired gas exchange related to excessive
production of sputum.
iii. Imbalanced nutrition less than body
requirement related to anorexia. 20
Ct--Nursing diagnosis:--
iv. Activity intolerance related to difficult
breathing.
v. Anxiety related to disease condition.
vi. Deficient knowledge related to lack of
information and education
Ct-----NURSING MANAGEMENT
21
Definition of asthma.
Causes of asthma.
Pathophysiology of asthma.
Clinical manifestations of asthma.
Diagnostic evaluation of asthma.
Management of asthma.
 Medical
 Nursing
SUMMARY
22
BIBLIOGRAPHY
• Smeltzer, S.C., Bare, B.G., Hinkle, J.L., & Cheever,
K.H. (2010). Brunner & Suddarth’s Textbook of
Medical-Surgical Nursing (12th ed.). Philadelphia:
Lippincott Williams & Wilkins.
• Black, J.M. & Hawks, J.H. (2009). Medical-Surgical
Nursing: Clinical Management for Positive
Outcomes (8th ed.). Philadelphia:
Elsevier/Saunders.
• Lewis, S.M., Dirkse, S.R., Heitkemper, M.M., &
Bucher, L. (2010). Medical-Surgical Nursing:
Assessment and Management of Clinical
Problems (7th ed.). St. Louis: Mosby.
23
24

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Asthma

  • 2. LEARNING OBJECTIVES At the end of this lecture the students should be able to:- Define asthma. Enumerate the causes of asthma. Explain about the pathophysiology of asthma. List out the clinical manifestations of asthma. Enumerate the diagnostic evaluation of asthma. Explain the management of asthma. 2
  • 3. Introduction • Asthma is a condition in which airways narrow and swell and may produce extra mucus. This can make breathing difficult and trigger coughing, a whistling sound (wheezing) when breathe out and shortness of breath. 3
  • 4. DEFINITION Asthma:---It is a chronic inflammatory disease of airway in which inflammation causes varying degree of obstruction in the airway. 4
  • 5. 5
  • 6. INCIDENCE • Asthma affect an estimated 20 million Americans. • Among adults, women have 30 % greater prevalence of asthma than men. • 39% higher in African Americans than in whites. • 4000 deaths per year. 6
  • 7. CLASSIFICATION OF ASTHMA ASTHMA Step 1 Mild intermittent Step 2 Mild persistent Step 3 Moderate persistent. Step 4 Severe persistent. 7
  • 8. 8
  • 9. 1. Exact cause unknown. 2. Triggers:- Allergens- IgE receptors mast cells. Exercise induced asthma. Respiratory infections. CAUSES OF ASTHMA 9
  • 10. Nose & sinus problems.  Allergic Rhinitis.  Nasal polyps.  Sinusitis.  Smoking Ct--CAUSES OF ASTHAMA 10
  • 11. • Drugs & food additives. • Gastro esophageal reflux disease (GERD). • Emotional stress. • Genetic factors. • Bugs in house , pollen Ct--CAUSES OF ASTHMA 11
  • 12. Release of mediators from the mast cells like eosinophils, basophils, macrophages, lymphocytes. Early phase response (with in 30 – 60 min) Late phase response (with in 5 – 6 hours). IgE mast cells mediated response Triggers PATHOPHYSIOLOGY 12
  • 13. •Bronchial smooth muscle constriction. •Excessive mucus secretion. •Vascular leakage. •Mucosal edema. •Infiltration by eosinophils, basophils, neutrophils. •Inflammation. •Bronchial hyperactivity. •Infiltration with monocytes, lymphocytes. •Obstruction of large & small airways. • Air trapping •Respiratory acidosis •hypoxemia 13
  • 14. 1. Wheezing, fever. 2. Dyspneoa, chest pain. 3. Cough with sputum. 4. Prolonged expiration. 5. Signs & symptoms of hypoxemia. CLINICAL MANIFESTATIONS 14
  • 15. 7. Restlessness & increased anxiety. 8. Increased pulse & B.P. 9. Pulsus paradoxus. 10.Tachypnea. 11.Absence of normal breath sounds. Ct---CLINICAL MANIFESTATIONS 15
  • 16. 1. History taking. 2. Physical examination. 3. Pulmonary function test. 4. Chest x- ray. 5. Peak flow monitoring. 6. Blood studies. 7. Sputum culture sensitive examination. DIAGNOSTIC EVALUATION 16
  • 17. Medical management: 1. Anti inflammatory drugs:-- i. Corticosteroids ii. Chronolyn sodium, nedochronil (for children). iii. Lucoterine modifiers, e.g. zafirlucast, zeileuton, montelucast. 2. Bronchodilators:-- e.g. β- adrenergic agents, methylxanthine preparations, anticholinergic agents. TREATMENT 17
  • 18. Ct---TREATMENT 3. Mast cell stabilizers. 4. Anti IgE antibody. 5. Β2 sympathomimetics. 18
  • 19. • Pneumothorax. • Rib fracture. • Atelectasis. • Pneumonia. • Pneumomediastinum. • Status asthmaticus. COMPLICATIONS 19
  • 20. NURSING MANAGEMENT Nursing diagnosis. i. Ineffective breathing pattern related to disease condition. ii. Impaired gas exchange related to excessive production of sputum. iii. Imbalanced nutrition less than body requirement related to anorexia. 20
  • 21. Ct--Nursing diagnosis:-- iv. Activity intolerance related to difficult breathing. v. Anxiety related to disease condition. vi. Deficient knowledge related to lack of information and education Ct-----NURSING MANAGEMENT 21
  • 22. Definition of asthma. Causes of asthma. Pathophysiology of asthma. Clinical manifestations of asthma. Diagnostic evaluation of asthma. Management of asthma.  Medical  Nursing SUMMARY 22
  • 23. BIBLIOGRAPHY • Smeltzer, S.C., Bare, B.G., Hinkle, J.L., & Cheever, K.H. (2010). Brunner & Suddarth’s Textbook of Medical-Surgical Nursing (12th ed.). Philadelphia: Lippincott Williams & Wilkins. • Black, J.M. & Hawks, J.H. (2009). Medical-Surgical Nursing: Clinical Management for Positive Outcomes (8th ed.). Philadelphia: Elsevier/Saunders. • Lewis, S.M., Dirkse, S.R., Heitkemper, M.M., & Bucher, L. (2010). Medical-Surgical Nursing: Assessment and Management of Clinical Problems (7th ed.). St. Louis: Mosby. 23
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