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Approach to ADHD in children
Dr vijay warad
Sai speciality clinic,satara road
Inamdar and sahyadri hospitals,pune
What comes to your Mind ?
INTRODUCTION
ADHD is one of the most common childhood
Neurobehavioural disorders
First described by Dr. Heinrich Hoffman in 1845
“The Story of Fidgety Philip”
In 1902, Sir Geroge Still described the condition
First published report in 1937 of stimulant
medication in ADHD
ADHD often continues into Adolescence and
Adulthood
What Is ADHD?
ADHD, or attention deficit hyperactivity
disorder, is a Behavioral Condition
characterized by inattention, impulsiveness,
and/or hyperactivity.
Approximately 1-20% of Indian children
have ADHD
Source – Indian Academy of Pediatrics
Persistent pattern of inattention and / or
hyperactivity and impulsive behaviour
that is more severe than that expected
in children of that age and level of
development.
Definition
PREVALENCE
Prevalence of ADHD 3 -10% ( Rowland et al
2002)
Affects 5% of school children (1/ class room)
More common in boys 4 – 9:1 (Gender bias)
Recent revised estimate 2 – 4:1 (Safer & Malever
2000)
ASSOCIATED FEATURES
School failure
Poor planning, organization and task
performance
Speech and language problems
Poor motor co-ordination
Enuresis
Instability
High stimulus seeking
Low frustration tolerance
ASSOCIATED CO-MORBID CONDITION
Language and learning disability (10-15% have
ADD)
Tourette’s syndrome (70% have ADHD)
Oppositional Defiant Disorders (33% of ADHD)
Conduct Disorders (25 -50% of ADHD)
Major Depression (20% of ADHD)
Anxiety Disorders (25% of ADHD)
ADHD COMORBIDITY
Secondary Complications
of Rhinitis
Allergic inflammation does not necessarily limit itself to the nasal airway
 Asthma : up to 80% of asthma patients have accompaning AR,38% of AR have
asthma
 Chronic sinusitis
 Otitis media
 Hearing difficulties
 Facial changes
 Failure to thrive
 Behavioural disorders (hyperactivity)
 Increased Social & emotional issues affect learning & ability to integrate with
peers
 Uncontrolled AR & adverse effects of sedating medications affect cognitive
functions
 Pneumonias
 COPD
What Are the Symptoms of ADHD?
Hyperactivity
Impulsivity
Inattention
Child's functioning in social and
academic settings, Interfere…
Paying attention to tasks at home or school
Making careless errors
Being easily distracted
Not following through with tasks or
completing instructions
Bored, losing things, being forgetful, having
difficulty organizing tasks
Being fidgety, seated at one place
Talking excessively
How Do I Know if a Child Has
ADHD?
Many of the symptoms of ADHD are also
symptoms seen during normal childhood
and development
Exhibiting one or more of the symptoms
does not mean that a child has ADHD
NEVER JUMP TO CONCLUSION
 The DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth
edition) Below is the Diagnostic Criteria for diagnosing Attention Deficit
(Hyperactivity) Disorder:
 A. Either (1) or (2)
 1) Six or more of the following symptoms of inattention have persisted
for at least six months to a degree that is maladaptive and inconsistent
with the developmental level:
 Inattention
 often fails to give close attention to details or makes careless mistakes in
schoolwork, work, or other activities
 often has difficulty sustaining attention in tasks or play activities
 often does not seem to listen when spoken to directly
 often does not follow through on instructions and fails to finish
schoolwork, chores, or duties in the workplace (not due to oppositional
behaviour or failure of comprehension)
 often has difficulty organizing tasks and activities
 often avoids, dislikes, or is reluctant to engage in tasks that require
sustained mental effort (such as schoolwork or homework)
 often loses things necessary for tasks or activities at school or at home
(e.g. toys, pencils, books, assignments)
 is often easily distracted by extraneous stimuli
 if often forgetful in daily activities
 2) Six or more of the following symptoms of hyperactivity-impulsivity
have persisted for at least 6 months to a degree that is maladaptive
and inconsistent with the developmental level:
 Hyperactivity
 often fidgets with hands or feet or squirms in seat
 often leaves seat in classroom or in other situations in which remaining
seated is expected
 often runs about or climbs excessively in situations in which it is
inappropriate (in adolescents or adults, may be limited to subjective feelings
of restlessness)
 often has difficulty playing or engaging in leisure activities quietly
 often talks excessively
 is often 'on the go' or often acts as if 'driven by a motor'
 Impulsivity
often has difficulty awaiting turn in games or group situations
 often blurts out answers to questions before they have been completed
 often interrupts or intrudes on others, e.g. butts into other children's games
 B. Some hyperactivity - impulsive or inattentive symptoms that cause
 impairment were present before the age of 7 years.
 C. Some impairment from the symptoms is present in more than two or more
settings (e.g. at school or work or at home).
 D. There must be clear evidence of clinically significant impairment in social,
academic, or occupational functioning.
 E. The symptoms do not occur exclusively during the course of a Pervasive
Developmental Disorder, Schizophrenia, or other Psychotic Disorder, and are
not better accounted for by another mental disorder (e.g. Mood Disorder,
Anxiety Disorder, Dissociative Disorder, or a Personality Disorder).
Symptoms of Hyperactivity
in ADHD
The child often fidgets with hands or feet or
squirms in their seat
The child often leaves the seat in the
classroom or in other situations in which
remaining seated is expected
The child often talks excessively.
Symptoms of Impulsivity in ADHD
The child often blurts out answers before
the questions have been completed
The child often experiences difficulty
awaiting his or her turn
The child often interrupts or intrudes on
others
Symptoms of Inattention in ADHD
The child often fails to give attention to
details, or makes careless mistakes in
schoolwork, work, or other activities.
The child often has difficulty sustaining
attention in tasks or play activities.
LIFE TIME COMORBID DISORDERS
Shekim WO, et al Comprehensive Psychaitry 1990; 31(5):416-425
Biedermen J, et al. Am. J. Psychiatry 1993; 150(12): 1792-1798
PSUD: Psychoactive substance use disorder; MDD: Major
Depressive Disorder ; LD: Learning disability;
ASP: Antisocial personality
PRESENTING FEATURES
Look for features of dyslexia, dysgraphia
Cruelty towards people, animals
Destruction of property, stealing
Delinquent behavior
Argumentative, disobedient, defiant, Back answers, quick
to take offense
PRESENTING FEATURES
Excessive crying or worry
Preoccupation with death or suicides
Neglect of self environment, antisocial
Low self esteem
Substance abuse
DIFFERENTIAL DIAGNOSIS
Mental Retardation with Hyperactivity
Under stimulation for highly intelligent children
Hyperthyroidism
Lead poisoning
Seizures (Petit Mal, Non Convulsion Status)
Medication – AED’s, antihistaminic, decongestants etc.
Chronic illness, sleep disorders
COMPREHENSIVE MANAGEMENT
PROTOCOLS
Screening in pre-school and school children
Assessment to fit DSM IV Criteria
Evaluation for co-morbid conditions
Investigations when indicated
Pharmacological treatment
Psychological treatment
Lifestyle modification
TREATMENT PLAN
Psycho-education of parent, teacher, child
BT initially for mild to moderate ADHD
Psycho-stimulants strongly recommended for
moderate to severe ADHD
Combination of both is most beneficial
Constant follow up since it’s a chronic condition
Medicines
 Automoxetin: Axpeta (25 mg,50 mg)
Above 6 years preffered
 Methylphenidate:- Inspiral,Adwise 10 mg,20 mg
ALTERNATIVE THERAPIES
Omega-3 fatty acids
Hypnosis
EEG biofeedback
Yoga, meditation
Ginkgobiloba
Mega-Vitamin Therapy
OMEGA -3 FATTY ACIDS
3 Major Type ingested in food
ALA – Alpha Linolenic Acid
EPA – Eicosapentaenoic Acid
DHA – Docosahexaenoic Acid
Once ingested Body converts ALA to EPA & DHA
DIETARY SOURCES
ALA – in Flax seeds, Canola Oil, Walnuts
DHA – in Seafood, Tuna, Salmon
EPA – Whole Grains, Garlic, Olive Oil
MECHANISM OF ACTION
Blocks action of cytokines
Enhance Neurotrophic activity in Synapses
Forms an essential part in physicochemical properties of
cell membranes, oligodendrocytes and astrocytes
(Purdue Study, Durham Study, Richardson and Puri Study)
STUDY WITH OMEGA 3 FATTY ACID
Study on pre school children with LD and ADHD
showed significant improvement in cognitive &
behavioural functions after 12 weeks of O3 Fatty Acid
(Richardson + Puri Oxford Univ.)
Study of Pregnant ladies given O3 Fatty Acid
supplement --- Children followed upto 5-6 years age
significant different in learning capabilities and
academic performance (Meherban Singh)
Docosahexaenoic Acid for Reading, Cognition and
Behavior in Children Aged 7–9 Years: A Randomized,
Controlled Trial (The DOLAB Study)
Alexandra J. Richardson*, Jennifer R. Burton, Richard P. Sewell, Thees F.
Spreckelsen, Paul Montgomery
Centre for Evidence-Based Intervention, University of Oxford, Oxford, United
Kingdom
PROGNOSIS
About 60-80% of childhood ADHD continue into Adolescent
& adults.
They may out grow Impulsivity and Hyperactivity.
Inattention and Disorganization persist and may worsen.
Adults with H/o ADHD in childhood have higher rates of
antisocial, criminal behaviour, Injuries, accidents, teen
pregnancies
Employment and Marital difficulties.
May need treatment and follow up lifelong.
ADHD
Low self
esteem
Academic
limitations
Relationships
Smoking and
substance abuse
Injuries
Motor vehicle
accidents
Legal
difficulties
Occupational/
vocational
Symptoms of ADHD through the
life cycle
Treatment Option…
Very IMPORTANT…
COGNIUM SYP CLINICAL
TRIALS
Proven in a Comparative clinical trial with 60 ADHD
Childrens,for 16 weeks
-Conducted by Dr.Vwarad,MD(Paed)in Pune
-Conducted on 2 Group of 300 children each,Gr
A&Gr B
-group A with cognium syrup and Behavioral therapy
-Group B with Behavirol therapy alone
-Assesssed by VANDERBILT ASSESSMENT SCALE
Approach to adhd
Approach to adhd
Approach to adhd
Approach to adhd

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Approach to adhd

  • 1. Approach to ADHD in children Dr vijay warad Sai speciality clinic,satara road Inamdar and sahyadri hospitals,pune
  • 2. What comes to your Mind ?
  • 3. INTRODUCTION ADHD is one of the most common childhood Neurobehavioural disorders First described by Dr. Heinrich Hoffman in 1845 “The Story of Fidgety Philip” In 1902, Sir Geroge Still described the condition First published report in 1937 of stimulant medication in ADHD ADHD often continues into Adolescence and Adulthood
  • 4. What Is ADHD? ADHD, or attention deficit hyperactivity disorder, is a Behavioral Condition characterized by inattention, impulsiveness, and/or hyperactivity. Approximately 1-20% of Indian children have ADHD Source – Indian Academy of Pediatrics
  • 5. Persistent pattern of inattention and / or hyperactivity and impulsive behaviour that is more severe than that expected in children of that age and level of development. Definition
  • 6. PREVALENCE Prevalence of ADHD 3 -10% ( Rowland et al 2002) Affects 5% of school children (1/ class room) More common in boys 4 – 9:1 (Gender bias) Recent revised estimate 2 – 4:1 (Safer & Malever 2000)
  • 7. ASSOCIATED FEATURES School failure Poor planning, organization and task performance Speech and language problems Poor motor co-ordination Enuresis Instability High stimulus seeking Low frustration tolerance
  • 8. ASSOCIATED CO-MORBID CONDITION Language and learning disability (10-15% have ADD) Tourette’s syndrome (70% have ADHD) Oppositional Defiant Disorders (33% of ADHD) Conduct Disorders (25 -50% of ADHD) Major Depression (20% of ADHD) Anxiety Disorders (25% of ADHD)
  • 10. Secondary Complications of Rhinitis Allergic inflammation does not necessarily limit itself to the nasal airway  Asthma : up to 80% of asthma patients have accompaning AR,38% of AR have asthma  Chronic sinusitis  Otitis media  Hearing difficulties  Facial changes  Failure to thrive  Behavioural disorders (hyperactivity)  Increased Social & emotional issues affect learning & ability to integrate with peers  Uncontrolled AR & adverse effects of sedating medications affect cognitive functions  Pneumonias  COPD
  • 11. What Are the Symptoms of ADHD? Hyperactivity Impulsivity Inattention
  • 12. Child's functioning in social and academic settings, Interfere… Paying attention to tasks at home or school Making careless errors Being easily distracted Not following through with tasks or completing instructions Bored, losing things, being forgetful, having difficulty organizing tasks Being fidgety, seated at one place Talking excessively
  • 13. How Do I Know if a Child Has ADHD? Many of the symptoms of ADHD are also symptoms seen during normal childhood and development Exhibiting one or more of the symptoms does not mean that a child has ADHD NEVER JUMP TO CONCLUSION
  • 14.  The DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, fourth edition) Below is the Diagnostic Criteria for diagnosing Attention Deficit (Hyperactivity) Disorder:  A. Either (1) or (2)  1) Six or more of the following symptoms of inattention have persisted for at least six months to a degree that is maladaptive and inconsistent with the developmental level:  Inattention  often fails to give close attention to details or makes careless mistakes in schoolwork, work, or other activities  often has difficulty sustaining attention in tasks or play activities  often does not seem to listen when spoken to directly
  • 15.  often does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace (not due to oppositional behaviour or failure of comprehension)  often has difficulty organizing tasks and activities  often avoids, dislikes, or is reluctant to engage in tasks that require sustained mental effort (such as schoolwork or homework)  often loses things necessary for tasks or activities at school or at home (e.g. toys, pencils, books, assignments)  is often easily distracted by extraneous stimuli  if often forgetful in daily activities
  • 16.  2) Six or more of the following symptoms of hyperactivity-impulsivity have persisted for at least 6 months to a degree that is maladaptive and inconsistent with the developmental level:  Hyperactivity  often fidgets with hands or feet or squirms in seat  often leaves seat in classroom or in other situations in which remaining seated is expected  often runs about or climbs excessively in situations in which it is inappropriate (in adolescents or adults, may be limited to subjective feelings of restlessness)  often has difficulty playing or engaging in leisure activities quietly  often talks excessively  is often 'on the go' or often acts as if 'driven by a motor'
  • 17.  Impulsivity often has difficulty awaiting turn in games or group situations  often blurts out answers to questions before they have been completed  often interrupts or intrudes on others, e.g. butts into other children's games  B. Some hyperactivity - impulsive or inattentive symptoms that cause  impairment were present before the age of 7 years.  C. Some impairment from the symptoms is present in more than two or more settings (e.g. at school or work or at home).  D. There must be clear evidence of clinically significant impairment in social, academic, or occupational functioning.  E. The symptoms do not occur exclusively during the course of a Pervasive Developmental Disorder, Schizophrenia, or other Psychotic Disorder, and are not better accounted for by another mental disorder (e.g. Mood Disorder, Anxiety Disorder, Dissociative Disorder, or a Personality Disorder).
  • 18. Symptoms of Hyperactivity in ADHD The child often fidgets with hands or feet or squirms in their seat The child often leaves the seat in the classroom or in other situations in which remaining seated is expected The child often talks excessively.
  • 19. Symptoms of Impulsivity in ADHD The child often blurts out answers before the questions have been completed The child often experiences difficulty awaiting his or her turn The child often interrupts or intrudes on others
  • 20. Symptoms of Inattention in ADHD The child often fails to give attention to details, or makes careless mistakes in schoolwork, work, or other activities.
  • 21. The child often has difficulty sustaining attention in tasks or play activities.
  • 22. LIFE TIME COMORBID DISORDERS Shekim WO, et al Comprehensive Psychaitry 1990; 31(5):416-425 Biedermen J, et al. Am. J. Psychiatry 1993; 150(12): 1792-1798 PSUD: Psychoactive substance use disorder; MDD: Major Depressive Disorder ; LD: Learning disability; ASP: Antisocial personality
  • 23. PRESENTING FEATURES Look for features of dyslexia, dysgraphia Cruelty towards people, animals Destruction of property, stealing Delinquent behavior Argumentative, disobedient, defiant, Back answers, quick to take offense
  • 24. PRESENTING FEATURES Excessive crying or worry Preoccupation with death or suicides Neglect of self environment, antisocial Low self esteem Substance abuse
  • 25. DIFFERENTIAL DIAGNOSIS Mental Retardation with Hyperactivity Under stimulation for highly intelligent children Hyperthyroidism Lead poisoning Seizures (Petit Mal, Non Convulsion Status) Medication – AED’s, antihistaminic, decongestants etc. Chronic illness, sleep disorders
  • 26. COMPREHENSIVE MANAGEMENT PROTOCOLS Screening in pre-school and school children Assessment to fit DSM IV Criteria Evaluation for co-morbid conditions Investigations when indicated Pharmacological treatment Psychological treatment Lifestyle modification
  • 27. TREATMENT PLAN Psycho-education of parent, teacher, child BT initially for mild to moderate ADHD Psycho-stimulants strongly recommended for moderate to severe ADHD Combination of both is most beneficial Constant follow up since it’s a chronic condition
  • 28. Medicines  Automoxetin: Axpeta (25 mg,50 mg) Above 6 years preffered  Methylphenidate:- Inspiral,Adwise 10 mg,20 mg
  • 29. ALTERNATIVE THERAPIES Omega-3 fatty acids Hypnosis EEG biofeedback Yoga, meditation Ginkgobiloba Mega-Vitamin Therapy
  • 30. OMEGA -3 FATTY ACIDS 3 Major Type ingested in food ALA – Alpha Linolenic Acid EPA – Eicosapentaenoic Acid DHA – Docosahexaenoic Acid Once ingested Body converts ALA to EPA & DHA
  • 31. DIETARY SOURCES ALA – in Flax seeds, Canola Oil, Walnuts DHA – in Seafood, Tuna, Salmon EPA – Whole Grains, Garlic, Olive Oil
  • 32. MECHANISM OF ACTION Blocks action of cytokines Enhance Neurotrophic activity in Synapses Forms an essential part in physicochemical properties of cell membranes, oligodendrocytes and astrocytes (Purdue Study, Durham Study, Richardson and Puri Study)
  • 33. STUDY WITH OMEGA 3 FATTY ACID Study on pre school children with LD and ADHD showed significant improvement in cognitive & behavioural functions after 12 weeks of O3 Fatty Acid (Richardson + Puri Oxford Univ.) Study of Pregnant ladies given O3 Fatty Acid supplement --- Children followed upto 5-6 years age significant different in learning capabilities and academic performance (Meherban Singh) Docosahexaenoic Acid for Reading, Cognition and Behavior in Children Aged 7–9 Years: A Randomized, Controlled Trial (The DOLAB Study) Alexandra J. Richardson*, Jennifer R. Burton, Richard P. Sewell, Thees F. Spreckelsen, Paul Montgomery Centre for Evidence-Based Intervention, University of Oxford, Oxford, United Kingdom
  • 34. PROGNOSIS About 60-80% of childhood ADHD continue into Adolescent & adults. They may out grow Impulsivity and Hyperactivity. Inattention and Disorganization persist and may worsen. Adults with H/o ADHD in childhood have higher rates of antisocial, criminal behaviour, Injuries, accidents, teen pregnancies Employment and Marital difficulties. May need treatment and follow up lifelong.
  • 35. ADHD Low self esteem Academic limitations Relationships Smoking and substance abuse Injuries Motor vehicle accidents Legal difficulties Occupational/ vocational Symptoms of ADHD through the life cycle
  • 37. COGNIUM SYP CLINICAL TRIALS Proven in a Comparative clinical trial with 60 ADHD Childrens,for 16 weeks -Conducted by Dr.Vwarad,MD(Paed)in Pune -Conducted on 2 Group of 300 children each,Gr A&Gr B -group A with cognium syrup and Behavioral therapy -Group B with Behavirol therapy alone -Assesssed by VANDERBILT ASSESSMENT SCALE