The document discusses recent advances in treatments for autistic spectrum disorders. It outlines typical developmental milestones from 7 months to 2 years and associated "red flags". It then discusses the emergence of a new model for autism that sees it as environmentally triggered and influenced by genetics, involving both brain and body abnormalities. Topics covered include autism being a medical rather than mental disorder, and treatments including educational and developmental therapies, behaviorally-based treatments, medical/biological treatments, and mind-body medicine. Common complementary and alternative treatments are also outlined, including their hypothesized mechanisms and safety. The role of heavy metals, yeast overgrowth, leaky gut, methylation, methylcobalamin supplementation, and chelation therapy in
Presentation that looks at the current clinical research on possible causes of Autism Spectrum Disorders. Includes brief mention of the use of Homeobotanicals in secondary symptom treatment management.
Presentation that looks at the current clinical research on possible causes of Autism Spectrum Disorders. Includes brief mention of the use of Homeobotanicals in secondary symptom treatment management.
A power point presentation on Autism Spectrum disorders I created in collaboration with a team of three other graduate students at the University of Dayton.
Complex developmental disability in infancy and early childhood, sign and symptom, its treatment via therapist approaches across the child's daily life
Introduction to Depressive Disorders in Children and AdolescentsStephen Grcevich, MD
This is the slide set to the lectures I provided to the medical staff of Child and Adolescent Behavioral Health in Canton, OH during the Fall-Winter of 2018
The Integrative Treatment of Depression, Schizophrenia & Autism - IMMH 2015Louis Cady, MD
This is the first of three lectures given by Dr. Cady at the 6th annual Integrative Medicine and Mental Health Conference in San Diego, on September 18, 2015. In it, Dr. Cady deconstructs the contributing factors to either exacerbating or causing a diagnosable mental disorder. The use of understanding the pathophysiology of the entire body, and not just firing antidepressants and other psychotropic drugs blindly into the patient without thinking, is clearly reviewed.
A power point presentation on Autism Spectrum disorders I created in collaboration with a team of three other graduate students at the University of Dayton.
Complex developmental disability in infancy and early childhood, sign and symptom, its treatment via therapist approaches across the child's daily life
Introduction to Depressive Disorders in Children and AdolescentsStephen Grcevich, MD
This is the slide set to the lectures I provided to the medical staff of Child and Adolescent Behavioral Health in Canton, OH during the Fall-Winter of 2018
The Integrative Treatment of Depression, Schizophrenia & Autism - IMMH 2015Louis Cady, MD
This is the first of three lectures given by Dr. Cady at the 6th annual Integrative Medicine and Mental Health Conference in San Diego, on September 18, 2015. In it, Dr. Cady deconstructs the contributing factors to either exacerbating or causing a diagnosable mental disorder. The use of understanding the pathophysiology of the entire body, and not just firing antidepressants and other psychotropic drugs blindly into the patient without thinking, is clearly reviewed.
The video for this presentation is available on our Youtube channel:
https://youtube.com/allceuseducation A continuing education course for this presentation can be found at https://www.allceus.com/member/cart/index/index?c=
Psychopharmacology: Antidepressants, Antipsychotics and Mood Stabilizers
Dr. Dawn-Elise Snipes PhD, LPC-MHSP, LMHC, NCC, CCDC
Executive Director, AllCEUs.com
Objectives
For each of the following, antidepressants, antipsychotics and mood stabilizers
Examine their method of action
Explore the types of disorders they are used to treat
Review the most common medications in those classes
Identify where to get more information for patients
Discuss the benefits and drawbacks to off-label prescribing
Supporting Systems in the body that impact AutismBrandi Kanya
Because the autism spectrum is so broad and complex, no universal approach to care is going to fit the needs of each child affected by this challenge.
Many different elements enter into the bigger picture, so recognizing and diagnosing what makes each particular case unique is critical to remediating the associated conditions.
Anderson, Unorthodox Health Care Cost Reductionsjwanderso
Novel Big Hitter interventions that will have dramatic cost savings due to improved health. Chronic diseases of aging and how to prevent them with unorthodox, effective interventions.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. By the end of 7 months
Smile back at another person
Respond to sound with sounds
Enjoy social play
Red Flags
• No big smiles or other warm, joyful
expressions by six months or thereafter
• No back-and-forth sharing of sounds,
smiles, or other facial expressions by nine
months or thereafter
3. By the end of 12 months
Use simple gestures
Imitate actions in their play
Respond when told “no”
Red Flags
• No back-and-forth gestures, such as
pointing, showing, reaching, or waving bye
• Not answering to one’s name when called
• No babbling – mama, dada, baba
4. By the end of 18 months
Do simple pretend play
Point to interesting objects
Use several single words unprompted
Red Flags
• No single words by 18 months
• No simple pretend play
5. By the end of 2 years
(24 months)
Use 2- to 4-word phrases
Follow simple instructions
Become more interested in other children
Point to object or picture when named
Red Flags
• No two-word meaningful phrases (without
imitating or repeating)
• Lack of interest in other children
6. Red Flag: Any loss of speech or
babbling or social skills
Regression at any age is cause for
immediate referral
7. The emergence of a
new autism model
Older model
• Genetically determined
• Brain based
• Hard-wired
• Treatable but not curable
Is autism a BRAIN
DISORDER?
Newer model
• Environmentally triggered
• Genetically influenced
• Both brain and body
• Metabolic abnormalities play big
role
• Treatable and recovery possible
OR is it
A DISORDER THAT
AFFECTS THE BRAIN?
8. Topics
AUTISM is A Medical condition .
It is not a mental Disorder
As such it is preventable
Treatable .
8
9. Treatment
Goals
Minimize core features and associated deficits
Maximize functional independence and QOL
Alleviate family stress
Educational intervention
Developmental Therapies
Communication
Sensory, fine motor, gross motor
Behaviorally Based treatments
Core and associated symptoms
Social skills
Medical or biologic treatments
Support family in home and community
10. ABA (Applied Behavioral Analysis)
General behavioral teaching approach involves reinforcement
and consequences to shape behavior
All of our parents used it!
Involves the A, B, C’s
Not airway, breathing circulation
Antecedent
Behavior
Consequence
11. Speech/Language Therapy
Behaviorally based/ intensive structured teaching
E.g., Verbal Behavior
Augmentative strategies
Sign language
PECS
Aided augmentative/ alternative system(s)
Decrease non-communicative language
Developmental-pragmatic approaches
appropriate use of language in social situations
e.g., SCERTS
Social skills training
12. Adjunct to educational,
developmental & behavioral
treatments
So far no evidence of impact
on core symptoms
Evidence supporting is
variable
Toolkit – handouts for MD &
families
Treat target symptoms
Stereotypies
Withdrawal
Obsessions
Irritability
Hyperactivity
attention span
self-injurious behavior
Aggression
sleep
13. Mind-body Medicine
Yoga
Music Therapy
Manipulative and Bodybased
Chiropractic
Massage/Therapeutic Touch
Auditory Integration
Energy Medicine
Transcranial & magnetic
stimulation
Biologically Based
Most commonly used
~ 50% - biologically based
30% - mind body
25% - manipulation/ body
based
** Most use > 1 modality
15. One of most commonly used CAM treatments
Hypothesis :
Exogenous opiate-like peptides = false neurotransmitters
Evidence – most non-blinded; few RCT emerging, no differences
Requires
elimination of ALL dairy products (not “GFCF except for ice
cream…”) & elimination of barley, rye, oats & wheat products
Potential deficiencies
Inherently deficient in calcium, vitamin D
B vits, Iodine, others may be lower in substitute products
Weight typically adequate, monitor Fe status
16. Another approach to therapy
Dealing with the yeast overgrowth.
Dealing with the leaky gut.
Heavy metals and their effects.
Chelation.
Methylcobalamin.
16
17. with before dealing with
the heavy metal issue
There are 3 main issues common to all autistic Children
1. Yeast Overgrowth
2. Leaky gut
3. Heavy Metal Accumulation
17
18. Yeast Overgrowth
Yeast overgrowth leads to poor absorption of
necessary vitamins, minerals & esssential nutrients.
It is normal to have a small amount of yeast in the GI
tract. Autistic children however have abnormal
amounts, usually leading to poor absorption of
essential nutrients and the leakage of toxic substances
into the bloodstream which should not be absorbed.
18
19. How do we treat the Yeast
overgrowth & Leaky gut
syndrome
Nutrition/Antioxidants in food and metabolised in
the body
Vitamins A, B Complex, C, E, B12 , B6, Folic Acid, Niacin
Essential Fatty Acids These are extremely important.
They are a most powerful anti-inflammatory agent.
Co-Enzyme Q10,DMG
Trace elements – Magnesium, Selenium, Chromium, Zinc
Probiotics
Reduced L glutathione,N Acetyl cysteine, Alpha-Lipoic
Acid
Anti-fungals medications.
Herbal Products,
19
20. and where do they come
from
Lead – petrol, paint, batteries, certain water mains
Mercury – fillings in teeth, fish, paint, numerous
appliances such as mercury thermometers, nasal
sprays and eye drops, certain vaccines.
Cadmium – Cigarettes, tyres, metal platings
Arsenic – Pesticides, chicken feeds, rice, treated
wood
20
21. and where do they come
from
Aluminum – Cooking wares, aluminum
foil, antacids, certain vaccines, canned
drinks/foods
Antimony – Carpets, flame retardant
clothes
Iron
Copper
21
22. Heavy Metals – how are we protected
against these free radicals
Diet /nutrition– “let food be your medicine
and let medicine be your food”- Hippocrates
Supplementation
Skin release
Good kidney eliminations
Good bowel eliminations
Exercise
Healthy lifestyle
22
23. What are the effects of these toxic metals
overload
They are oxidised to form free radicals resulting in
the destruction of cells,
They affect organs ,interfere with enzyme systems,
inhibit prostaglandin formation. Weaken the immune
system, inhibit the proper functioning of cells,
contribute to gastrointestinal problems, and are
carcinogenic.
23
24. What Chelation agents are there
1.
EDTA-Ethylene diamine tetra acetic acid
2.
DMSA(dimercocaptosuccinic acid)
3.
DMPS(dimercaptopropanesulfonic acid)
4.
TTFD Transdermal Allithiamine
24
25. How are they used
EDTA is effective only intravenously.It is used in
adults in the form of MG EDTA for Heart
Disease,Circulatory disorders,neurological disorders,
and the chronic degenerative diseases.
DMSA (dimercocaptosuccinic acid)
DMPS(Dimercaptopropanesulfonic acid)
TTFD/allathiamine (active form of B1)
25
26. EDTA and its safety
Given according to ACAM protocol millions of
chelations in past 30 years no recorded death.
Doctors licensed in western Canada since 1997 No
serious ADRS
NIH conducting $30 million clinical trial on 2,300
patients no serious adrs
NIH 800,000 I.V EDTA chelations in U.S. alone no
serious ADRS
Not suitable for ASD children 3 hour i.v. inneffective
in chelating mercury
Powerful chelator of all other toxic heavy metals
26
27. Metal Dertoxification in Auistic children
DMSA is the most widely used , convenient, safe , and
given orally. It is a good chelator of Mercury, Lead
and Cadmium.
Dmps May be given intravenously. A good chelator of
mercury,often used as a provovative agent, usually
given in oral form
27
28. Chelating With the oral chelators
DMSA is given orally according to the Dan protocol 10mg/kg body
weight/3times daily for three days on and 11 days off.
Repeat Full Blood Count and Blood chemistry tests at 3 to 4 month
intervals.
Mobilization and excretion of the heavy metals produces a shift in the
equilibrium between the various compartments of the body. This
exerts an almost magnetic effect on metals in depots which are not
directly accessible to the chelating agent. The body attempts to
restore an equilibrium between the depots again. The heavy metals
will then migrate partially into compartmenst where it is accessible to
the chelating agent.
28
29. Advantages of DMSA over DMPS
DMSA more widley used therefore greater experience with its use and
well established safety profile.
Well established in the DAN protocol.
No well established oral DMPS protocol.
DMPS used more in acute poisoning with Lead, Mercury, Arsenic etc.
DMSA is more effective in removing Mercury from the brain,
particularly when combined with Alpha Lipoic Acid.
29
30. Disadvantages of DMSA oral
therpay
DMSA may feed into the yeast/leaky gut/Gastrointestinal problems.
DMPS is not as severe on the gastrointestinal problems
DMPS used by some physiciansina once weekly dosage of 100 mg per
week
Is over 50 % absorbed
30
31. Methylcobalamin and
pharmacology
Metylathion is the process by which a single Carbon
atom is transferred from a Methyl donor to another
molecule.This process is essential to life itself.
Dr. Richard Deth of Boston believes that Thiomersail
interferes with the Metylathion process in converting
Vitamin B12 to Metylcobalamin.
In many cases Autsim can be treated effectively by
the Administration of Metyl B12 to augment the
Metylathion capacity.
31
32. Biosynthesis of Active Methylcobalamin
The low levels of Glutathione in autistic children will
adversely affect their ability to detoxify and protect
against heavy metals such as Thiomersal.
32
33. Impaired Methylation
As impaired Methylation is important in Autism, the
administration of Methylcobalamin should bring
about an improvement.
Dr. James Neubrander has found significant
improvement with injections of Methylcobalamin by
giving the Methylcobalamin every 3 days.
Improvements were noted in Attention, language
ability and social skills.
33
34. How is Methylcobalamin given?
Dosage recommendation is 65 micrograms per
Kilogram Bodyweight every 3 days.
This means that as much as 1250 micrograms is
present in 0.05ml
The needle 30 gauge 3/10 Ultrafine BD insulin. It may
be given by the parent while the child is sleeping.
It is inserted into the buttock at a 30 – 45 degree
angle just under the skin.
34
36. Concentrated Metylcobalamin by Injection
Metylcobalamin is the active Co-enzyme element of
B12
B12 is present in the brain and central nervous system
as Metylcobalamin & is Non toxic.
It is known that Metylcobalamin metabolism is
impaired in the Autistic child.
Much information on this is available for Dr.
Neubrander.
36
37. Typical Naturopathic
Treatment Plan
Heavy Metal Toxicity
Gastrointestinal Health
Wheat (gluten) and milk (casein) free diet
Candida diet (sugar, arabinose, tartaric acid)
Hypoallergic diet to prevent autoimmunity
Anti-inflammatory diet to control inflammation
Supplements including EFA, probiotics, glutamine,
MCT
Asses presence of heavy metals
Investigate heavy metal exposure
Undergo chelation therapy for removal of heavy
metals
Brain Chemisty
Evaluate levels of Glutamate/GABA,
serotonin and dopamine
38. Nutrition
Why does food matter?
Opium, gluten and milk in Autism
Breakdown of gluten and casein by secretions of the pancreas and the
intestines create peptides (small proteins) that are similar in structure
to endorphins (the body’s natural pain killer). These peptides have
opiate-like qualities.
Normally, these peptides are degraded and excreted with little effect.
In autistic patients, these peptides can lead to reduced brain electrical
activity and thus altered behavioural changes.
This activity is improved by naltrexone administration (an opioid
antagonist) therefore proving opioid action.
Much anecdotal evidence exists of significant improvement in autistic
symptoms when milk and wheat are eliminated from the diet.
A study using 15 autistic children correlated significantly increased urine
exorphin level with autistic spectrum patients. Elimination of milk
and gluten from the diet resulted in improvement of social, cognitive
and communications sills, commensurate with reduction of urinary
exorphin level. Knivsberg et al, 1990
39. Treatment
Atypical antipsychotic, Abilify
(Aripiprazole) oral formulation
was approved November 24,
2009 by the FDA for the
treatment of irritability
associated with ASD in children
aged 6-17 years.
Data based on two 8 week,
randomized, placebo-controlled
multicenter studies evaluating
its efficacy for improving mean
scores on the Caregiver-rated
Irritability subscale of the
Aberrant Behavior Checklist
(ABC-I).
40. Multi dimensional approach
It should be remembered that improving Methylation
capacity is only one component of the multi
dimensional approach in the treatment of Autism.
Gluten Casein free diet
Nutritional supplementation
Chelating
Behavioural therapies
Pharmacotherapy
41
Editor's Notes
Numerous heavy metals which are toxic the most toxic are lead,mercury,cadmium,arsenic,aluminium,antimony,tin,nickel,thallium as well as ones that are essential but dangerous in excess namely Iron and copper which we will discuss later
When they enter the bodythey go thro a chemical biological processcalled oxidation and form free radicals.It is now indisputed that free radical damagecontributes significantly to the degeneratuve process of ageing.Act akin to sparks in a fire damagingcells and resulting in the diseases so often reffered as the ageing diseases.when cells are damaged they no longer function properly resulting in damage to the tissues andfinally to the organs of the body.Symptoms may not appearfor yearsas the body stores these toxins in various tissues.Bones and fatty deposits.Symptoms of chronic metal toxicity are therefore insidiousand non specifucand include fatigue,malaise and increased susceptility to infections.Excessive free radical activity cannot be avoided in todays environment.When this dagenerative process happens to the cells in your body you can easily see why you do not have the energy you should.You don’t repair as well as u used to,u get older more quickly and u wear out much faster than you want.When this process affects your blood vessels u develop circulatory problems leading to poor skin texture etc etc
Antioxidants in diet and producedin the body during the course of normal metabolism protect us by preventing these heavy metals from becoming oxidated and behaving as free radicals. Exaplles of antioxidants are etc etc.So a diet rich in these is advised.
For Example
Diet supplementation skinn release etc are all useful methods for dealing with heavy metals.Over time these natural processesare unable to defend us resulting in the diseases already mentioned