Flagyl is used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract. This medication will not treat a vaginal yeast infection.
Flagyl is used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract. This medication will not treat a vaginal yeast infection.
Pharmacology of commonly used antisep, disinfect, insecticideMr. Dipti sorte
Slides are prepared as per INC Syllabus Unit III Antiseptics & Disinfectants and it is most benefited for B sc Nursing students and faculty of the subject
short and simple study on the topic of laxative and purgatives which is very usefull for the student , teachers, as well as health cares peoples. this study is done by the student with the help of teachers
Sulphonamides Pharmacology For Pharmacy studentsMalay Pandya
This is the PowerPoint presentation of the Antimicrobial drug - SULPHOANMIDE.
Sulphonamide is the first antimicrobial agent
It Can be employed for suppressive therapy of chronic urinary tract infection, streptococcal pharyngitis and gum infection.
Combined with trimethoprim (cotrimoxazole) sulfamethoxazole is used for many bacterial infections.
This will be useful to all Pharmacy Student ...
A nitroimidazole antibiotic used particularly for;
Anaerobic bacteria &
Protozoa
Its an antimicrobial drug which is highly active against;
Anaerobic bacteria
Some protozoa
Amoeba
Thus metronidazole is an;
Antibiotic drug
Ameobicide
Antiprotozoal
Its common trade name is Fragyl in USA & Uganda
Tinidazole is similar to metronidazole but with a long duration of action
Pharmacology of commonly used antisep, disinfect, insecticideMr. Dipti sorte
Slides are prepared as per INC Syllabus Unit III Antiseptics & Disinfectants and it is most benefited for B sc Nursing students and faculty of the subject
short and simple study on the topic of laxative and purgatives which is very usefull for the student , teachers, as well as health cares peoples. this study is done by the student with the help of teachers
Sulphonamides Pharmacology For Pharmacy studentsMalay Pandya
This is the PowerPoint presentation of the Antimicrobial drug - SULPHOANMIDE.
Sulphonamide is the first antimicrobial agent
It Can be employed for suppressive therapy of chronic urinary tract infection, streptococcal pharyngitis and gum infection.
Combined with trimethoprim (cotrimoxazole) sulfamethoxazole is used for many bacterial infections.
This will be useful to all Pharmacy Student ...
A nitroimidazole antibiotic used particularly for;
Anaerobic bacteria &
Protozoa
Its an antimicrobial drug which is highly active against;
Anaerobic bacteria
Some protozoa
Amoeba
Thus metronidazole is an;
Antibiotic drug
Ameobicide
Antiprotozoal
Its common trade name is Fragyl in USA & Uganda
Tinidazole is similar to metronidazole but with a long duration of action
DESCRIBE AND DISCUSS ANTISEPTICS AND DISINFECTANTS.pptxPushpaPushpa59
DESCRIBE AND DISCUSS ANTISEPTICS AND DISINFECTANTS.pptx
DESCRIBE AND DISCUSS ANTISEPTICS AND DISINFECTANTS.pptx
DESCRIBE AND DISCUSS ANTISEPTICS AND DISINFECTANTS.pptx
DISINFECTANTS are chemical agents that inhibit or kill microorganisms (surgical apparatus, periphery of the patient, and the objects used by the patient).
Disinfection It is the application of chemicals to destroy most pathogenic organisms on inanimate surfaces
Can be accomplished by application of chemical agents, use of physical agents (ionizing radiation) dry or moist heat, superheated steam(autoclave, 120̊ C)
idela surfactant
effective at room temperature,
noncorrosive and nontoxic,
inexpensive,
capable of killing the vegetative form of all pathogenic organisms,
require limited time of exposure
Above ppt includes different types of disinfectants used in microbiology ,classification of disinfectants, and also it includes some important techniques like Plasma sterilization ,ETO sterilization and bleaching of water.
Hello friends. In this PPT I am talking about antiseptics, disinfectants. If you like it, please do let me know in the comments section. A single word of appreciation from you will encourage me to make more of such videos. Thanks. Enjoy and welcome to the beautiful world of pharmacology where pharmacology comes to life. This video is intended for MBBS, BDS, paramedical and any person who wishes to have a basic understanding of the subject in the simplest way.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
2. Are anti-infective substances
Which are use on the skin & mucous membrane or on
inanimate object.
To reduce or kill microorganisms.
They are non-selective & some of them are toxic
3. These are the substances or medium by removing or
killing all micro-organisms including vegetative form of
bacteria, viruses, fungii, spores, parasite
Which are present every where responsible for
contamination and infection.
4. Destruction or inhibition of growth of all pathogenic
organisms (bacteria, viruses, fungii) on non living surfaces
But not the spores on the surface or any medium
If spores are also killed process is Sterlization
5. These are substances which inhibit the growth or kill
micro-organisms on living surfaces such as skin & mucous
membrane. It prevent tissue infection
6. Good antiseptic/disinfectant
1. Rapid acting
2. Chemically stable
3. Cheap & Cidal
4. Non staining & good odour
5. Active against all pathogens
6. Active in presence of pus, blood & exudates
7. Non irritating to tissues / non corrosive
8. Non absorbable
9. Non sensitizing (no allergy)
7. Oxidation of bacterial protoplasm
– Potassium permagnate, H202, Halogens
Co-agulation (denaturation) of bacterial proteins &
disrupt cell membrane
– Phenols, chlorhexidine, alcohols, aldehydes
Detergent like action ↑ permeability of bacterial cell
membrane
– Cetrimide, soaps
10. Methyl Derivative of phenol, less damaging to tissues
than phenol.
3-10 times more active
Used for disinfection of utensils, excreta & washing
hands.
11. Phenol derivative
Does not co-agulate proteins,
Non corrosive, Non irritating to skin
Poorly water soluble
Commercial used 4.8 % solution for surgical antisepsis
Skin cream & soap: 0.8%
Mouth wash 1%
12. Chlorinated phenol act by inhibiting enzymes
Causing bacterial lysis.
Commonly use in soap
Effectively only against Gm+ve
Slow but persistant action
>2% preparations banned
13. Potassium permagnate: – Purple crystals, highly water soluble,
Liberates oxygen which oxidizes bacterial protoplasm.
Used for gargling, irrigating wounds, urethra (condy's lotion
diluted solution of 1:4000 to 1:10,000 )
High conc cause burns & blistering
It is also used to disinfect water in ponds.
Stomach wash in alkaloidal poisoning
14. Hydrogen Peroxide: – liberates nascent oxygen which
oxidizes necrotic matter & bacteria.
Helps in loosening & removing slough, ear wax etc.
Benzoyl Peroxide: – Widely used drug for acne.
liberates O2 in presence of water which kills bacteria,
specially anaerobes
16. Rapidly acting broad spectrum (bacteria, fungi, virus)
Acts by iodinating and oxidizing microbial protoplasm.
1:20000 solution kill most vegetative forms even bacterial
spores are kill with higher concentration/longer action
Used on cuts, degerming skin before surgery, treat ring
worm.
Adverse effect: cause burns & blisters
17. Known as povidine iodine.
Non toxic, nonirritating, non staining prolonged
germicidal action.
Used on boils, furunculosis, burns, ulcers, tinea,
disinfecting endoscopes & surgical instruments, surgical
scrubbing, non specific vaginitis.
18. Rapid action and Potent germicide 0.1 to 0.25 ppm kill
most pathogens.
Kills pathogens in 30 sec.
Used to disinfect urban water supplies.
More active in acidic or neutral medium
19. (1) Chlorinated lime (bleaching powder)
– obtained by action of chlorine on lime.
– used to disinfect drinking water & swimming pools
(2) Sodium hypochlorite
– Powerful disinfectant used in dairies for milk cans.
– Too Irritant to be used as antiseptic.
– Root canal therapy in dentistry
20. Chlorhexidine: (Savlon) Acts by disrupting bacterial cell
membrane & denaturation of bacterial proteins
Non irritant, more active against gram+ve bacteria.
Used in for surgical scrub, neonatal bath, mouth wash &
general skin antiseptic.
Most widely used antiseptic in dentistry 0.12-0.2% oral
rinse or 0.5 -1 % tooth paste
21. Antiseptics cetrimide
Detergents:- Cidal to bacteria, fungi & viruses.
Act by altering permeability of cell membrane
Efficiently remove dirt and grease
Widely used as antiseptics & disinfectants for surgical
instruments, gloves etc
Combined with chlorhexidine (savlon)
22. Anionic detergents
Weak antiseptics with cleansing action
Washing with soap & warm water one of the most effective
methods of preventing disease transmission
Affect only Gm+ bacteria
23. Ethanol – Antiseptic, cleansing agent at 40-90% conc.
Act by precipating bacterial proteins
Recommended for decontamination of hands in the health
care & personal hygiene
Irritant, should not be applied on mucous membrane, ulcers
Open wounds produce burning sensation .
24. Used for fumigation.
37 % aqueous solution called as formalin.
Protoplasmic poison , denaturants proteins.
Used for preserving dead tissues.
Use as antiseptic restricted due to bad odour & irritation
Glutaraldehyde :- is a better sterlizing agent
Broad spectrum activity against bacteria, fungi & viruses
25. Boric acid :- weak antiseptic , bacteriostatic.
Used for mouth wash, irrigation eyes,
Boroglycerine pant use stomatitis and glossitis.
Adverse effect: systemic absorption cause vomiting,
abdominal pain diarrhoea, visual disturbance & kidney
damage.
26. SILVER COMPOUNDS
Silver sulphadiazine :- is active against pseudomonas seen in
burns patient.
Silver nitrate :- rapidly kill & highly active against gonococci -
1% solution used
ZINC COMPOUNDS
Zinc Salts:- used as eye wash, ear drops, acne.
Calamine and zinc sulfate:- Mild antiseptic, insoluble
27. Gentian violet:- Active against (gram + ve), bacteria, fungi
Used on chronic ulcers, furunculosis, bed sores, ring
worms infected, eczema.
Acriflavine and proflavine:-
Active against gram +ve bacteria & gonocci
Suitable for chronic ulcers & wounds
Do not retard healing, non irritant
28. These are drugs used to kill parasites that live on body
surfaces
Lice → cause pediculosis (hair infection)
Mites → cause scabies(skin infection)
30. Broad spectrum causes neurological paralysis in insects.
100 % cure rate nearly
Single application needed in most cases.
Few patients experience itching ,burning.
first drug of choice for scabies & pediculosis.
Scabies: apply all over the body except face & head .
Wash after 8- 12 hrs.
Head lice:- massage about 30 g in to scalp & wash after 10
min.
31. Broad spectrum insecticide which kills lice & mites by
penetrating their chitinous cover & affecting nerves system
Properties similar to permethrin.
Cure rate low & resistance seen.
Disadvantage:-
Lipid soluble CNS toxicity like vertigo, convulsions seen.
Application similar to permithrin.
If Combination with benzyl benzoate is more effective.
32. Oily liquid with aromatic smell.
Cure rate 76–100% second application required after 24 hrs.
Toxicity is low, Application similar to permethrin.
Use has declined due to skin irritation.
Contraindication in children because of neurological
symptoms & skin irritation.
Combination with lindane highly effective.
33. Effective scabicide, pediculocide & antipruritic
Low cure rates
Better results if applied for twice at 24 hr interval & washed
off days after that
Less irritation & toxicity
May be preferred in children as second choice
34. Scabicide, weak pediculocide, antiseptic, fungicide & keratolytic.
These is dissolve cuticle of itch mite and kill it.
Scrubbing bath (open burrows) ointment is massaged over body
(below the neck) for 3 consecutive days
Disadvantages:
(a) Treatment is messy.
(b) Produces bad odour—socially unacceptable
(c) Repeated applications are required.
35. Popular insecticide for mosquitoes, flies and other pests.
Used in dust or watery suspension form
Pediculosis & scabies 1–2% lotion or ointment is applied &
washed off after 12–24 hours.
Poorly absorbed through skin cause rashes, muscle
weakness, tremor.
Very high doses produce convulsions & neurotoxin
It gets stored in body fat & induces microsomal enzymes.
Combination with benzyl benzoate is more effective.
36. Anti helminthic drug which has been recently found
effective against scabies & pediculosis.
A single 0.2 mg/kg ( 12mg in adults)
Has 91- 100 % cure rate.
Contra indicated in children 5yrs, pregnant & lactating
women.
