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GLIDANTS
ANTICAKING AGENTS
Presentation by D.A.Dasuni Prasadika
Bpharm
Content
■ Introduction of glidants
■ Functions and examples of glidants
■ Definition of anticaking agents
■ Examples of anticaking agents
Introduction of glidants
Glidant is a substance that is added to a powder to improve its
flowability.
■ A glidant’s effect is due to a counteraction of factors resulting in poor flowability of
powders.
■ For instance, correcting surface irregularity reducing interparticular friction.
■ The result is a decrease in the angle of repose which is an indication of an enhanced
powder’s flowability .
Functions of glidants.
■ To improve powder flowability
■ To reduce interparticular friction
■ To reduce the cohesion
Examples -:
■ Magnesium sterate
■ Aerosol , colloidal silicon dioxide
■ Starch and talc.
Definition of Anticaking agents
Anticaking agent is an additive placed in powdered or granulated materials to
prevent the formation of lumps, easing packaging,transport and consumption .
■ Function of anticaking agents
By competing with host powder for moisture anticaking agents have strong water adsorptive
ability.
So that they can compete with host powdered medicine product particles for available water
thus, reducing hygroscopicity consequently its tendency to cake.
So the function is adsorbing excess moisture or by coating particles and making them water
repellent .
Examples for anticaking agents
■ Calcium carbonate
■ Magnesium carbonate
■ Sodium aminosilicate
■ Sodium ferrocyanide
■ Potassium ferrocyanide
THANKYOU

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Anticaking agents and Glidants

  • 1. GLIDANTS ANTICAKING AGENTS Presentation by D.A.Dasuni Prasadika Bpharm
  • 2. Content ■ Introduction of glidants ■ Functions and examples of glidants ■ Definition of anticaking agents ■ Examples of anticaking agents
  • 3. Introduction of glidants Glidant is a substance that is added to a powder to improve its flowability. ■ A glidant’s effect is due to a counteraction of factors resulting in poor flowability of powders. ■ For instance, correcting surface irregularity reducing interparticular friction. ■ The result is a decrease in the angle of repose which is an indication of an enhanced powder’s flowability .
  • 4. Functions of glidants. ■ To improve powder flowability ■ To reduce interparticular friction ■ To reduce the cohesion Examples -: ■ Magnesium sterate ■ Aerosol , colloidal silicon dioxide ■ Starch and talc.
  • 5. Definition of Anticaking agents Anticaking agent is an additive placed in powdered or granulated materials to prevent the formation of lumps, easing packaging,transport and consumption . ■ Function of anticaking agents By competing with host powder for moisture anticaking agents have strong water adsorptive ability. So that they can compete with host powdered medicine product particles for available water thus, reducing hygroscopicity consequently its tendency to cake. So the function is adsorbing excess moisture or by coating particles and making them water repellent .
  • 6. Examples for anticaking agents ■ Calcium carbonate ■ Magnesium carbonate ■ Sodium aminosilicate ■ Sodium ferrocyanide ■ Potassium ferrocyanide