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Antepartum Fetal Assessment
Presentor: Dr.Tanya Das
Moderator:Dr.Dipty Shrestha
contents
 Introduction
 Clinical Evaluation
 Fetal movements
 Fetal Breathing
 Contraction Stress Testing
 Non Stress Test
 Acoustic stimulation Test
 Biophysical Profile
 Amniotic Fluid Volume
 Doppler Velocimetry
Introduction
 Aims of antenatal Fetal Monitoring
1. To ensure satisfactory growth and well being of fetus
throughout pregnancy
2. To screen out the high risk factors that affect the growth
of the fetus
 Rationality of Antenatal Fetal Tests:
1. Tests must provide information superior to that of
clinical evaluation
2. Should be helpful in management to improve perinatal
outcome
3. Benefits of tests must outweigh the potential risks and
the costs
Significance of Fetal Testing
 Between 1970-1985, 15 year duration, fetal surveillance
increased from less than 1 percent in 1970 to 15 percent in
1980
 Women undergoing NST had a nonsignificant decreased
risk for stillbirth compared with those not tested– 3.6
versus 9.2 percent respectively
 A study conducted in 2003 concludedin their study of 36
preterm infants, that by the time fetal compromise is
diagnosed, fetal damage has already occurred
 Testing for biophysical profile decreased the rate of
cerebral palsy to 1.3 percent as compared to 4.7 percent in
untested women.
Antepartum Surveillance
 First Trimester
1. Clinical evaluation
2. Ultrasound evaluation
3. Chorionic Villus Sampling
4. Genetic screening using fetal cell free DNA
 Second Trimester
1. Amniocentesis
2. Fetal Echocardiography
3. Fetal Blood Sampling
 Third Trimester
1. Clinical Evaluation
2. Fetal biophysical Profile
3. Ultrasound Evaluation
4. Non Stress test
5. Contraction Stress Test
6. Vibroacoustic Stimulation Test
7. Fetal Doppler Ultrasound
Clinical evaluation of fetal well being
 First Visit
• Size of uterus determined: helps in estimating the correct
duration of gestation
 Subsequent visits
1. Maternal weight gain
2. Blood pressure
3. Size of uterus and fundal height
Antepartum Fetal Surveillance
 Objectives( ACOG)
1. Prevention of fetal death
2. Avoidance of unncessary interventions
Fetal Movements
 Passive unstimulated fetal activity commences
at 7 weeks
 Becomes organised between 20-30 weeks of
gestation
 Fetal movements maturation- until 36 weeks,
behavioural states established
 4 fetal behavioural states:
1. State 1F: quiescent state- quite sleep
2. State 2F: Frequent Gross body movements, continuous
eye movements, wider oscillation of FHR
3. State 3F: continous eye movements in absence of body
movements and no FHR acceleration
4. State 4F: Vigorous body movements, eye movements,
FHR accelerations; corresponds to awake state
 Mean length of quiet or inactive state-23 minutes
 Clinical Application
1. Cardiff ‘count 10’ formula- report if
: <10 movements occur in 12 hours on 2 successive days
:no movement perceived even after 12 hours in a single day
2. Daily Fetal Movement Count
Three counts each of 1 hour duration (morning, noon,
evening); if <10 in 12 hours(or less than 3 in each hour)
Fetal Breathing
 Chest wall movements are discontinuous in fetus :
paradoxical chest wall movements
 >1 episode lasting >30 seconds
 2 types of chest wall movements:
1. Sighs or gasps(1-4/minute)
2. Irregular bursts of breathing (240 cycles/minute)
Biophysical Profile
Modified Biophysical Profile
 First line screening tests
 Combined non stress test with Amniotic fluid volume
 Less time to perform
 Less expertise
 Excellent fetal surveillance tool
 False negative rate of 0.8 per 1000 and false positive rate
of 1.5percent
Amniotic Fluid Volume
 Decreased uteroplacental perfusion may lead to
diminished fetal renal blood flow– decreased urine
production– oligohydramnios
 ACOG(2012a)- amnitoic fluid index <5cm or a
maximum deepest vertical pocket <2cm are
acceptable criteria for diagnosis of oligohydramnios
Contraction Stress Test
 Measure fetal response to transient reduction in fetal
oxygen delivery during uterine contraction
 Test of uteroplacental insufficiency
 Intravenous Oxytocin used to induce contractions and
FHR response is recorded
 Nipple stimulation can be used alternatively to induce
contractions
Non Stress Test
 Test of fetal condition
 FHR accelerations in response to fetal movement is
recorded
 National Institute of child health and human development
fetal monitoring workshop-
• > 32 weeks- accelerations of 15 beats per minute for >15
seconds above baseline
• <32 weeks- accelerations of 10 beats per minute for > 10
seconds above baseline
 Normal NST (ACOG and AAP 2012)
‘ 2 or more accelerations that peak at 15 beats per minute
or more above baseline each lasting for 15 seconds or
more in a 20 minute reading’
( >40 minute Tracing required to conclude insufficient fetal
activity accounting to fetal sleep pattern)
90% or higher false positive rate
 Abnormal Non Stress Tests
• NST non-reactive for 90 minutes: 93% associated with
perinatal pathology
• Baseline oscillation <5 beats per minute
• Absent accelerations
• Late deccelerations with uterine contractions
• Variable Deccelerations, if non-repetetive and brief—less
than 30 seconds—do not indcate fetal compromise
• Repetetive variable deccelerations: at least 3 in 20 minutes
or lasting more than 1 minute– suspect compromise
 Interval Between Testing
ACOG(2012a): twice weekly for women with post
term pregnancy, multifetal gestation, type 1 diabetes
mellitus, fetal growth restriction, gestational
hypertension
Acoustic Stimulation Tests
 Loud external sounds have been used– provoke heart rate
accelerations
 Commercially available stimulator – stimulus of 1 to 2
seconds , can be repeated upto 3 times for up to 3 seconds
 Positive response is defined as the rapid appearance of
qualifying acceleration following stimulation
Doppler Velocimetry
 3 fetal vascular circuits– umbilical artery, middle cerebral
artery, and ductus venosus are assessed
 Aid in decision to interfere in growth restricted fetus
 Umbilical Artery Velocimetry
• Systolic-diastolic ratio(S/D) ratio is considered abnormal
if it is above 95th centile for gestational age or if diastolic
flow is decreased or reversed
• Absent or reversed diastolic flow– signifies increased
impedance to umbilical artery blood flow
• Results from poorly vascularized placental villi- seen in
fetal growth restriction
• Seen in IUGR, PIH, GDM, Post term pregnancy, Anti-
phospholipid antibody syndrome
 Middle cerebral Artery
• Hypoxic fetus attempts brain sparing by reducing
cerebrovascular impedance and thus increasing
blood flow
• Incresed diastolic velocity, decreased S/D ratio
• Seen in Rh Isoimmunisation, Fetal Anemia, D
alloimmunisation and IUGR
 Ductus Venosus
• Most recent
• Best predictor of perinatal Outcome
• Information about forward cardiac function
• Negative or reversed flow in ductus venosus is a late
finding in fetal acidemia
 Antenatal Testing Recommendations
• Majority of high risk pregnancies, recommended
testing begin by 32 to 34 weeks
• Pregnancies with severe complications might require
testing as early as 26-28 weeks
• Frequency of testing: 7 days
 Thank you

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Antepartum fetal assessment

  • 1. Antepartum Fetal Assessment Presentor: Dr.Tanya Das Moderator:Dr.Dipty Shrestha
  • 2. contents  Introduction  Clinical Evaluation  Fetal movements  Fetal Breathing  Contraction Stress Testing  Non Stress Test  Acoustic stimulation Test  Biophysical Profile  Amniotic Fluid Volume  Doppler Velocimetry
  • 3. Introduction  Aims of antenatal Fetal Monitoring 1. To ensure satisfactory growth and well being of fetus throughout pregnancy 2. To screen out the high risk factors that affect the growth of the fetus  Rationality of Antenatal Fetal Tests: 1. Tests must provide information superior to that of clinical evaluation 2. Should be helpful in management to improve perinatal outcome 3. Benefits of tests must outweigh the potential risks and the costs
  • 4. Significance of Fetal Testing  Between 1970-1985, 15 year duration, fetal surveillance increased from less than 1 percent in 1970 to 15 percent in 1980  Women undergoing NST had a nonsignificant decreased risk for stillbirth compared with those not tested– 3.6 versus 9.2 percent respectively  A study conducted in 2003 concludedin their study of 36 preterm infants, that by the time fetal compromise is diagnosed, fetal damage has already occurred  Testing for biophysical profile decreased the rate of cerebral palsy to 1.3 percent as compared to 4.7 percent in untested women.
  • 5. Antepartum Surveillance  First Trimester 1. Clinical evaluation 2. Ultrasound evaluation 3. Chorionic Villus Sampling 4. Genetic screening using fetal cell free DNA  Second Trimester 1. Amniocentesis 2. Fetal Echocardiography 3. Fetal Blood Sampling
  • 6.  Third Trimester 1. Clinical Evaluation 2. Fetal biophysical Profile 3. Ultrasound Evaluation 4. Non Stress test 5. Contraction Stress Test 6. Vibroacoustic Stimulation Test 7. Fetal Doppler Ultrasound
  • 7. Clinical evaluation of fetal well being  First Visit • Size of uterus determined: helps in estimating the correct duration of gestation  Subsequent visits 1. Maternal weight gain 2. Blood pressure 3. Size of uterus and fundal height
  • 8. Antepartum Fetal Surveillance  Objectives( ACOG) 1. Prevention of fetal death 2. Avoidance of unncessary interventions
  • 9. Fetal Movements  Passive unstimulated fetal activity commences at 7 weeks  Becomes organised between 20-30 weeks of gestation  Fetal movements maturation- until 36 weeks, behavioural states established
  • 10.  4 fetal behavioural states: 1. State 1F: quiescent state- quite sleep 2. State 2F: Frequent Gross body movements, continuous eye movements, wider oscillation of FHR 3. State 3F: continous eye movements in absence of body movements and no FHR acceleration 4. State 4F: Vigorous body movements, eye movements, FHR accelerations; corresponds to awake state  Mean length of quiet or inactive state-23 minutes
  • 11.
  • 12.  Clinical Application 1. Cardiff ‘count 10’ formula- report if : <10 movements occur in 12 hours on 2 successive days :no movement perceived even after 12 hours in a single day 2. Daily Fetal Movement Count Three counts each of 1 hour duration (morning, noon, evening); if <10 in 12 hours(or less than 3 in each hour)
  • 13. Fetal Breathing  Chest wall movements are discontinuous in fetus : paradoxical chest wall movements  >1 episode lasting >30 seconds  2 types of chest wall movements: 1. Sighs or gasps(1-4/minute) 2. Irregular bursts of breathing (240 cycles/minute)
  • 14.
  • 15.
  • 17.
  • 18. Modified Biophysical Profile  First line screening tests  Combined non stress test with Amniotic fluid volume  Less time to perform  Less expertise  Excellent fetal surveillance tool  False negative rate of 0.8 per 1000 and false positive rate of 1.5percent
  • 19. Amniotic Fluid Volume  Decreased uteroplacental perfusion may lead to diminished fetal renal blood flow– decreased urine production– oligohydramnios  ACOG(2012a)- amnitoic fluid index <5cm or a maximum deepest vertical pocket <2cm are acceptable criteria for diagnosis of oligohydramnios
  • 20. Contraction Stress Test  Measure fetal response to transient reduction in fetal oxygen delivery during uterine contraction  Test of uteroplacental insufficiency  Intravenous Oxytocin used to induce contractions and FHR response is recorded  Nipple stimulation can be used alternatively to induce contractions
  • 21.
  • 22. Non Stress Test  Test of fetal condition  FHR accelerations in response to fetal movement is recorded  National Institute of child health and human development fetal monitoring workshop- • > 32 weeks- accelerations of 15 beats per minute for >15 seconds above baseline • <32 weeks- accelerations of 10 beats per minute for > 10 seconds above baseline
  • 23.  Normal NST (ACOG and AAP 2012) ‘ 2 or more accelerations that peak at 15 beats per minute or more above baseline each lasting for 15 seconds or more in a 20 minute reading’ ( >40 minute Tracing required to conclude insufficient fetal activity accounting to fetal sleep pattern) 90% or higher false positive rate
  • 24.
  • 25.  Abnormal Non Stress Tests • NST non-reactive for 90 minutes: 93% associated with perinatal pathology • Baseline oscillation <5 beats per minute • Absent accelerations • Late deccelerations with uterine contractions • Variable Deccelerations, if non-repetetive and brief—less than 30 seconds—do not indcate fetal compromise • Repetetive variable deccelerations: at least 3 in 20 minutes or lasting more than 1 minute– suspect compromise
  • 26.
  • 27.
  • 28.
  • 29.  Interval Between Testing ACOG(2012a): twice weekly for women with post term pregnancy, multifetal gestation, type 1 diabetes mellitus, fetal growth restriction, gestational hypertension
  • 30. Acoustic Stimulation Tests  Loud external sounds have been used– provoke heart rate accelerations  Commercially available stimulator – stimulus of 1 to 2 seconds , can be repeated upto 3 times for up to 3 seconds  Positive response is defined as the rapid appearance of qualifying acceleration following stimulation
  • 31. Doppler Velocimetry  3 fetal vascular circuits– umbilical artery, middle cerebral artery, and ductus venosus are assessed  Aid in decision to interfere in growth restricted fetus
  • 32.  Umbilical Artery Velocimetry • Systolic-diastolic ratio(S/D) ratio is considered abnormal if it is above 95th centile for gestational age or if diastolic flow is decreased or reversed • Absent or reversed diastolic flow– signifies increased impedance to umbilical artery blood flow • Results from poorly vascularized placental villi- seen in fetal growth restriction • Seen in IUGR, PIH, GDM, Post term pregnancy, Anti- phospholipid antibody syndrome
  • 33.
  • 34.  Middle cerebral Artery • Hypoxic fetus attempts brain sparing by reducing cerebrovascular impedance and thus increasing blood flow • Incresed diastolic velocity, decreased S/D ratio • Seen in Rh Isoimmunisation, Fetal Anemia, D alloimmunisation and IUGR
  • 35.
  • 36.  Ductus Venosus • Most recent • Best predictor of perinatal Outcome • Information about forward cardiac function • Negative or reversed flow in ductus venosus is a late finding in fetal acidemia
  • 37.
  • 38.  Antenatal Testing Recommendations • Majority of high risk pregnancies, recommended testing begin by 32 to 34 weeks • Pregnancies with severe complications might require testing as early as 26-28 weeks • Frequency of testing: 7 days