The document summarizes angiogenesis, which is the growth of new blood vessels from pre-existing vessels. It describes the multi-step process of angiogenesis including initiation, endothelial cell migration and proliferation, and maturation. Key growth factors that stimulate angiogenesis like VEGF and FGF are discussed as well as inhibitors like endostatin and angiostatin that regulate the process. Pathological angiogenesis and potential clinical applications of modulating angiogenesis to treat conditions like chronic wounds and ischemia are also mentioned.

2. Presented by : Mr. Nirav S. Vachhani M.Pharm Pharmacology (Sem-1) Guided by : Dr. Rina H. Gokani S. J. Thakkar pharmacy college, Rajkot.

8. “ Activated” endothelial cells  Proteases Degradation of BM EC migration EC proliferation Lumen formation Recruitment Of pericytes --new BM Fusion – New vessels Initiation of Blood Flow