This document discusses several common alterations in respiratory function including pulmonary edema, lower respiratory tract infections, traumatic injuries, neurological diseases, adult respiratory distress syndrome, chronic obstructive pulmonary diseases, upper respiratory tract infections, atelectasis, industrial diseases, and obesity. It outlines the clinical manifestations and critical care management of patients with these respiratory conditions.
Bacterial: effects aged and immunosupressed, antibacterial drugs have reduced the mortality significantly and shortened illness Decreased clearance rate of common bacteria (Increased susceptability of the host or decrease work of macrophages) Pneumococcal Pneumonia : 30 – 80% of CAP Viral: mild and self-limiting by adults. May progress to bacterial pneumonia due to susccepability of person Aspiration: unconscious or decreased LOC at high risk
Rib #s – voluntary support, decreased TV
Pleural Effusion R) side – also from neoplasms, infection, PE, Normally pleural fluid is produced absorbed prodeced, etc… to provide a smooth line within the plueral space.
Pneumo: Air enters the pleural space Heamo: Blood in the plueral space
Mediastinal Shift - pressure builds up and pushes the mediastinal cavity to the unaffected side, the lung may collapse creating a life threatening situation Cardiac Tamponade - collection of blood in pericardial/mediastinal space may compress the myocardium compromising cardiac function and cardiac output
One bottle system creates seal. Air out but not in… Any positive pressure greater then 2cm H2O will expel air. Suction is not regulated. If fluid enters the bottle
One bottle system creates seal. Air out but not in… Any positive pressure greater then 2cm H2O will expel air. Suction is not regulated. If fluid enters the bottle
Spinal cord: trauma – qaud / para Motor nerve: Tick-bite paralysis, Guillain-Barre syndrome Infectious: tetanus Muscle wasting: muscular dystrophy Guillain-Baree acute toxic polyneuritis – has varying degrees of muscle weakness and paralysis: respiratory complications are threefold Paralysis of the internal and external intercostal muscles reduces functional breathing ability – breathing becomes diaphramatic paralysis of the vagal nerve – gag reflex is lost
Acute Bronchitis : common condition caused by infection that results in inflammation of the mucosal lining of the tracheobroncial tree
Asthma : Acute airway obstruction. Characterised by recurrent paroxysms of wheezing and dyspnoea (not related to cardiac disease). Bronchospasm in response to various stimuli. Not all wheezing is asthma (eg aspitation, tumour). Extrinsic or intrinsic : extrinsic – specific allergies, childhood asthma is usually self-limiting, decrease severity as person matures. IgE mast cells respond, constriction of smooth muscle, increased secretions, inflammation response (cyclic) narrowing of airways. intrinsic – related to infection, exercise Fatigue is a major problem in asthma.
Bronchiectasis :irreversible dilation of the bronchi and broncioles – usually preceeded by infection and inflammation of the respiratory tract. Unknown if the disease is due to infection or abnormall structure. Common sympotoms include cough, symptoms of infection
Cystic Fibrosis : hereditary disorder in which large quantities of viscous material are secreted – early age onset Chronic Brobnchitits : continual bronchial inflammation and progressive increase in productive cough, not attributed to a specific cause. PATHO- thickening and rigidity of bronchial mucosa to chronic irritation. Closely related to emphysema but is usually defined as an abnormality that involves excessive secretion of mucus and bronchial inflammation.
Pulmonary Emphysema : most common chronic pulmonary disease and frequently classified with chronic bronchitis. Differs: CB v PE History: recurrent chest infections v not recurrent chest infections Chest exam: noisy v quiet General appearance: “blue bloater” v “pink puffer” / barrel chest Draw bell curve / continuum (Chronic bronchitis) ------------------ (majority w both) ------------------------- (pulmonary empysema)
Organo-phosphate poisoning: protect self!! Asbestosis Coal workers – fibrosis due to excess macrophases
Medications: Antibiotics Inotropes Steriods Prone positioning ( PaO2/FiO2 189±34 prone vs. 83±14 supine after 6 hours)