The document discusses three genera of gram-positive, filamentous bacteria: Actinomyces, Nocardia, and Streptomyces. Actinomyces can cause actinomycosis, a chronic infection of the cervico-facial, thoracic or abdominal areas. Nocardia commonly causes subcutaneous infections, pulmonary infections, and brain abscesses. Streptomyces is associated with mycetoma and can invade bone. Penicillin is often used to treat Actinomyces, while sulfonamides are frequently used for Nocardia and Streptomyces along with surgical debridement in some cases.