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MRI of fistula in ano
C HOEFFEL
JM TUBIANA
Objectives

•  Describe the impact of MRI in the
management of fistulas

•  Propose protocols and report forms
used for fistula in ano evaluation
Fistula in ano
•  Track communicating

with the rectum or the
anal canal via an
internal opening and
generally with an
external opening

•  Infection of an

intersphincteric glandfollowed by drainage of
the abscess in every
directions
WHY MRI ?
•  MRI versus clinical examination versus
endoanal ultrasound

–  104 patients evaluated with the three

modalities and follow-up (MRI or surgery) as
the gold standard.

•  MRI versus Clinical examination

–  Correct classification 90 vs 61 %
–  Best for detection of abscesses, of
horseshoe fistulas

Buchanan Radiology 2004
WHY MRI ?
•  MRI versus endoanal
ultrasonography

–  Internal opening 97 vs 91 %
–  Best detection of complex tracts and
abscesses with MRI

Buchanan Radiology 2004
WHY and WHEN MRI ?

•  First suspicion of fistula

–  30 patients with pre-operative MRI,

surgery and rectal exam under GA +
follow-up with surgery and 12 months
MRI. Disagreement n=15

• Minor disagreement , n=12
• Change in management, n=3
• MRI ‘s impact on treatment decisions = 10 %

Buchanan Br J Surg 2003
WHY and WHEN MRI ?

•  Recurrent Fistula 71 patients

–  Agreement surgery/MRI, n=40
• 5 with recurrent fistulas
–  Discrepancies surgery/ MRI, n=31
• 16 with recurrent fistula (52 %),

p=0.0005, at the location predicted by
MRI
• MRI guided surgery decreases recurrence
rate down to 75 %.

Buchanan Lancet 2002
WHY and WHEN MRI ?

•  Endoscopic Ultrasonography

–  Particularly for intersphincteric fistulas
–  Less accurate in case of sepsis or complex
fistulas

•  MRI

–  First-step examination in case of recurrent
fistula
–  If presence of a complex fistula at US or
clinical examination
–  Before anti-TNF treatment

Williams Dis Colon Rectum 2007
MRI : HOW ?

•  Technique
•  Anatomy
•  Classification
MRI Technique

•  Sequence Selection
•  Planes
•  Slices orientation
MRI Technique

•  1.5 Tesla ou 3 T
•  Phased-array coil, without any

preparation nor endorectal probe.
Sequences
–  Anatomical views Sag T2 - Ax T2 Pelvis
–  Fistula imaging
• STIR
• Fat Suppressed T2
• Gado Fat suppressed T1

3 DT2 w-TSE with post processing reformation ?
How to choose sequences ?

•  T2 FS / STIR

–  Simple
–  No injection
–  High signal intensity of the

inflammatory tract
–  Fibrous areas low signal
intensity
–  Less sensitive for very thin
tracts
–  Difficult to differentiate
inflammation from fluid
HALLIGAN Radiology 2006

Before tt STIR

After tt STIR
Sequences: How to choose?

•  T1 Gado FS

–  Injection
–  Inflammatory tract white
–  Fibrosis/Fluid black
–  May overinterpret a healing
fistula

T1 Gado FS
STIR vs T1 Gado FS
•  STIR versus T1 Gado FS

Gado FS

–  Overinterpretation of enhancement

with gado, while no fluid on STIR,
when a fistula is on its way to heal

B0

STIR
STIR vs T1 Gado FS
Differentiate granulation tissue from fluid
Before anti TNF treatment

Gado FS

STIR

Abscess?

Granulation tissue?

No abscess
STIR vs T1 Gado FS

STIR

Gado FS

Abscess
Sequences: How to choose?

•  Combined T1 Gado FS + STIR
•  Role of DW MRI?

T1 gado FS

Axial STIR

Axial diff b500
T2

Ax T1 Gado FS

Fusion diff-T2

Fusion diff-T2
MRI Technique
•  Slice thickness
–  3-4 mm
•  Section Planes
–  Axial - relationship to sphincters
–  Coronal - level of internal opening and
relationship to levator ani muscles.
–  Sagittal may be useful (anovaginal
fistula)
MRI Technique- Slice positioning
Important to assess the level of internal opening with regard to
puborectal muscle and better evaluation of relationship/ levator ani
MRI Technique

•  FOV – not just anal canal

–  In some cases must cover perineum,

presacral space, supralevatorian space
Anatomy
External Sphincter-T2
•  Prolongs puborectal muscle
•  Striated muscle
•  Circular
•  Hyposignal

2 cm
Anatomy
Internal
Sphincter- T2/
STIR
•  Prolongs rectal muscular
layer
•  Smooth muscle
•  Circular
•  Intermediate to high signal
GADO FS
Classification
• 

Why is it important?
ü Aims of surgery
o  Continence
preservation
o  Infectious foci and
secondary tracts
elimination
ü Surgical Options
o  Seton tight or not
o  FistulotomyFistulectomy
o  Intersphincteric
amputation, Flap
o  Fistulotomy-Fistulectomy

Pr Halligan
Intersphincteric
amputation
Superficial Fistula
Horsthuis AJR 2004
T2
Intersphincteric Fistula
Involvement of internal sphincter
No risk for continence

Horsthuis AJR 2004
Transphincteric Fistula
Involvement of both internal and external sphincters
External sphicter section threatens continence

Ax gado FS
Transphincteric Fistula
• 

Sometimes internal opening less obvious but predictable,
located at the penetrating point of the external sphincter
or at the epicenter of the intersphincteric sepsis.
Suprasphincteric Fistula 20 %
Rare, upwards and crosses the levator ani muscle.
Its section may threaten continence. Often inaccurately classified
Extrasphincteric Fistula= primitive rectal
disease (CD, cancer, diverticulitis)
Ax Gado FS
Complications

•  Abscess
Complications

Dr Damian Tolan, Leeds
Report
1.Fistula type - simple, complex,
anovaginal, horseshoe
Ax T2

fusion

Coro gado FS

Ax gado FS
Report
1.Fistula Type
2. Internal opening
Level and position (clockwise)
Report
1.Fistula type
2. Internal opening
Level and position (clockwise)

3. Primary fistula pathway to the
external opening
Location and hour
Report
1.Fistula type
2. Internal opening
Level and position (clockwise)

3. Primary fistula pathway to the
external opening
Location and hour
Report
1.Fistula type
2. Internal opening
Level and position (clockwise)

3. Primary fistula pathway to the
external opening
Location and hour

4. Number and position of
supralevatorian extensions?
Report
1.Fistula type
2. Internal opening
Level and position (clockwise)

3. Primary fistula pathway to the
external opening
Location and hour

4. Number and position of supralevatorian
extensions?
5. Number and positions of collections
Report

•  Activity Criteria
– Hypersignal T2
– Enhancement
Ax gado FS

T2 Stir
B0

B1000
Report

•  Sphincter
•  Rectum

T1 FS Gado
•  Main anatomic criteria
–  Fistula type
• 
• 
• 
• 

Simple
Complex
Horseshoe
Ano-vaginal

–  Relationship with levator
ani muscle

•  Inflammation criteria
–  Fistula
•  Hypersignal T2
•  Enhancemnet

–  Abscess
–  Rectal wall

–  Parks’classification
• 
• 
• 
• 

Intersphincteric
Transsphincteric
Suprasphincteric
Extrasphincteric

–  Openings

•  Others
–  Presence of a seton
–  Distant extension
–  Sphincteric ring
abnormalities (rupture…)
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana
Abdominal imaging ano fistula jm tubiana

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Abdominal imaging ano fistula jm tubiana

  • 1. MRI of fistula in ano C HOEFFEL JM TUBIANA
  • 2. Objectives •  Describe the impact of MRI in the management of fistulas •  Propose protocols and report forms used for fistula in ano evaluation
  • 3. Fistula in ano •  Track communicating with the rectum or the anal canal via an internal opening and generally with an external opening •  Infection of an intersphincteric glandfollowed by drainage of the abscess in every directions
  • 4. WHY MRI ? •  MRI versus clinical examination versus endoanal ultrasound –  104 patients evaluated with the three modalities and follow-up (MRI or surgery) as the gold standard. •  MRI versus Clinical examination –  Correct classification 90 vs 61 % –  Best for detection of abscesses, of horseshoe fistulas Buchanan Radiology 2004
  • 5. WHY MRI ? •  MRI versus endoanal ultrasonography –  Internal opening 97 vs 91 % –  Best detection of complex tracts and abscesses with MRI Buchanan Radiology 2004
  • 6. WHY and WHEN MRI ? •  First suspicion of fistula –  30 patients with pre-operative MRI, surgery and rectal exam under GA + follow-up with surgery and 12 months MRI. Disagreement n=15 • Minor disagreement , n=12 • Change in management, n=3 • MRI ‘s impact on treatment decisions = 10 % Buchanan Br J Surg 2003
  • 7. WHY and WHEN MRI ? •  Recurrent Fistula 71 patients –  Agreement surgery/MRI, n=40 • 5 with recurrent fistulas –  Discrepancies surgery/ MRI, n=31 • 16 with recurrent fistula (52 %), p=0.0005, at the location predicted by MRI • MRI guided surgery decreases recurrence rate down to 75 %. Buchanan Lancet 2002
  • 8. WHY and WHEN MRI ? •  Endoscopic Ultrasonography –  Particularly for intersphincteric fistulas –  Less accurate in case of sepsis or complex fistulas •  MRI –  First-step examination in case of recurrent fistula –  If presence of a complex fistula at US or clinical examination –  Before anti-TNF treatment Williams Dis Colon Rectum 2007
  • 9. MRI : HOW ? •  Technique •  Anatomy •  Classification
  • 10. MRI Technique •  Sequence Selection •  Planes •  Slices orientation
  • 11. MRI Technique •  1.5 Tesla ou 3 T •  Phased-array coil, without any preparation nor endorectal probe.
  • 12. Sequences –  Anatomical views Sag T2 - Ax T2 Pelvis –  Fistula imaging • STIR • Fat Suppressed T2 • Gado Fat suppressed T1 3 DT2 w-TSE with post processing reformation ?
  • 13. How to choose sequences ? •  T2 FS / STIR –  Simple –  No injection –  High signal intensity of the inflammatory tract –  Fibrous areas low signal intensity –  Less sensitive for very thin tracts –  Difficult to differentiate inflammation from fluid HALLIGAN Radiology 2006 Before tt STIR After tt STIR
  • 14. Sequences: How to choose? •  T1 Gado FS –  Injection –  Inflammatory tract white –  Fibrosis/Fluid black –  May overinterpret a healing fistula T1 Gado FS
  • 15. STIR vs T1 Gado FS •  STIR versus T1 Gado FS Gado FS –  Overinterpretation of enhancement with gado, while no fluid on STIR, when a fistula is on its way to heal B0 STIR
  • 16. STIR vs T1 Gado FS Differentiate granulation tissue from fluid Before anti TNF treatment Gado FS STIR Abscess? Granulation tissue? No abscess
  • 17. STIR vs T1 Gado FS STIR Gado FS Abscess
  • 18. Sequences: How to choose? •  Combined T1 Gado FS + STIR •  Role of DW MRI? T1 gado FS Axial STIR Axial diff b500
  • 19. T2 Ax T1 Gado FS Fusion diff-T2 Fusion diff-T2
  • 20. MRI Technique •  Slice thickness –  3-4 mm •  Section Planes –  Axial - relationship to sphincters –  Coronal - level of internal opening and relationship to levator ani muscles. –  Sagittal may be useful (anovaginal fistula)
  • 21. MRI Technique- Slice positioning Important to assess the level of internal opening with regard to puborectal muscle and better evaluation of relationship/ levator ani
  • 22. MRI Technique •  FOV – not just anal canal –  In some cases must cover perineum, presacral space, supralevatorian space
  • 23. Anatomy External Sphincter-T2 •  Prolongs puborectal muscle •  Striated muscle •  Circular •  Hyposignal 2 cm
  • 24. Anatomy Internal Sphincter- T2/ STIR •  Prolongs rectal muscular layer •  Smooth muscle •  Circular •  Intermediate to high signal
  • 26. Classification •  Why is it important? ü Aims of surgery o  Continence preservation o  Infectious foci and secondary tracts elimination ü Surgical Options o  Seton tight or not o  FistulotomyFistulectomy o  Intersphincteric amputation, Flap
  • 29.
  • 31. Intersphincteric Fistula Involvement of internal sphincter No risk for continence Horsthuis AJR 2004
  • 32.
  • 33. Transphincteric Fistula Involvement of both internal and external sphincters External sphicter section threatens continence Ax gado FS
  • 34. Transphincteric Fistula •  Sometimes internal opening less obvious but predictable, located at the penetrating point of the external sphincter or at the epicenter of the intersphincteric sepsis.
  • 35. Suprasphincteric Fistula 20 % Rare, upwards and crosses the levator ani muscle. Its section may threaten continence. Often inaccurately classified
  • 36.
  • 37. Extrasphincteric Fistula= primitive rectal disease (CD, cancer, diverticulitis)
  • 41. Report 1.Fistula type - simple, complex, anovaginal, horseshoe
  • 42. Ax T2 fusion Coro gado FS Ax gado FS
  • 43. Report 1.Fistula Type 2. Internal opening Level and position (clockwise)
  • 44. Report 1.Fistula type 2. Internal opening Level and position (clockwise) 3. Primary fistula pathway to the external opening Location and hour
  • 45. Report 1.Fistula type 2. Internal opening Level and position (clockwise) 3. Primary fistula pathway to the external opening Location and hour
  • 46. Report 1.Fistula type 2. Internal opening Level and position (clockwise) 3. Primary fistula pathway to the external opening Location and hour 4. Number and position of supralevatorian extensions?
  • 47. Report 1.Fistula type 2. Internal opening Level and position (clockwise) 3. Primary fistula pathway to the external opening Location and hour 4. Number and position of supralevatorian extensions? 5. Number and positions of collections
  • 49. Ax gado FS T2 Stir B0 B1000
  • 51. •  Main anatomic criteria –  Fistula type •  •  •  •  Simple Complex Horseshoe Ano-vaginal –  Relationship with levator ani muscle •  Inflammation criteria –  Fistula •  Hypersignal T2 •  Enhancemnet –  Abscess –  Rectal wall –  Parks’classification •  •  •  •  Intersphincteric Transsphincteric Suprasphincteric Extrasphincteric –  Openings •  Others –  Presence of a seton –  Distant extension –  Sphincteric ring abnormalities (rupture…)