This document discusses the emergence of cognitive informatics and its potential applications. It begins by summarizing the early development of software cognitive metrics to measure software complexity based on cognitive weights assigned to basic control structures. It then discusses issues and concerns with this approach, noting that cognitive informatics is needed to fully address questions about how the human mind works and varies across populations. The document outlines key areas of cognitive informatics research, including developing theoretical frameworks to model the brain, exploring common concepts between artificial and natural intelligence, and creating supporting mathematics. Ultimately, it argues that cognitive informatics has expanded from initially measuring software comprehension to become a transdisciplinary field with the potential to develop cognitive computers that mimic human-level intelligence.