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Complications of
Sinusitis
Dr. Krishna
Koirala
2017-08-30
Definition
• Progress of infection beyond the muco-
periosteal lining of paranasal sinuses to
involve the bone and neighboring
structures (orbit, intra-cranial cavity,
dentition)
• Compromise in function of any part of
Etiology
• Weak immune response of host
– Young children and immuno
-compromised adults
• Inadequate / inefficient treatment
• Infection by highly virulent organisms
• Abnormalities of muco- cilliary clearance
Routes of infection
• Via thin bones eg. lamina papyracea
• Through natural suture lines
• Through natural canal: infra-orbital canal
• Retrograde thrombophlebitis: diploic vein
of Breschet
• Closely related roots of upper 2nd
premolar & 1st
molar teeth
Classification
• Acute
– Local
•Orbital
•Intracranial
•Bony
•Dental
– Distant
•Toxic shock
syndrome
• Chronic
– Mucocele
– Pyocele
• Associated
diseases (?)
– Otitis media
– Adeno -tonsillitis
– Bronchiectasis
Orbital Complications ( Chandler
et al 1970)
1. Pre-septal cellulitis
2. Orbital cellulitis without abscess
3. Orbital cellulitis with extra/ sub-
periosteal abscess
4. Orbital cellulitis with intra-periosteal
abscess
Intracranial Complications
1. Meningitis
2. Encephalitis
3. Extra-dural abscess
4. Sub-dural abscess
5. Intra-cerebral abscess
6. Cavernous sinus thrombosis
7. Sagittal sinus thrombosis
• Bony
– Osteitis
– Osteomyelitis (Pott’s puffy tumour)
• Dental
− Dental abscess
− Oro-antral fistula
• Commonest complication of sinusitis 
• Young people at high risk: 85% < 20 yrs
age 
• Ethmoid sinus most commonly implicated
→ Frontal → Sphenoid → Maxillary 
• Left orbit more commonly involved (?)
Orbital complications
Pre-septal cellulitis
• Inflammation external to orbital septum
• Edema of eyelids:
– Upper lid : frontal sinusitis
– Lower lid : maxillary sinusitis
– Both lids : ethmoid sinusitis
• No tenderness , visual loss , limitation of
extra-ocular movement
Orbital Cellulitis without
abscess
• Inflammation of adipose tissue deep to
peri-orbital septum without suppuration
• Diffuse peri -orbital edema with
erythema
• Mild proptosis
• No restriction of extra-ocular movement
• No change in vision
Extra-periosteal abscess
• Most common form of orbital cellulitis
• Localized extra-periosteal pus collection
• Mild proptosis, restriction of extra-ocular
movement , vision loss
• Color vision affected first
– Red = brown
– Blue = black
Extra-periosteal
abscess
Orbital cellulitis with Intra-
periosteal abscess
• Mild chemosis (edema of conjunctiva)
• Proptosis: severe, asymmetric,
quadrantic
– Frontal sinusitis : down + forward +
lateral
– Ethmoid sinusitis : forward + lateral
– Maxillary sinusitis : up + forward
• Concurrent and complete
Intra-periosteal abscess
Cavernous Sinus Thrombosis
• Rapid onset, hectic fever
• Bilateral orbital pain + severe chemosis
• Bilateral absent pupillary reflex
• Bilateral symmetrical axial proptosis
• Sequential ophthalmoplegia (VI → III →
IV)
• Papilledema + loss of vision
• Painful paresthesia of V1, V2
Cavernous Sinus Thrombosis
B/L chemosis + proptosis
Cavernous sinus
Thrombosis
Orbital
abscess
Bilateral Unilateral
Rapidly progressive Slowly
progressive
Hectic fever Low grade fever
Severe chemosis Mild chemosis
Paraesthesia of V1, V2 No paraesthesia
Sequential
ophthalmoplegia
Concurrent
pan-
ophthalmoplegia
Symmetric axial
proptosis
Asymmetric
quadrantic
Evaluation of orbital
complication
• Ophthalmology consultation
– Look for edema of eyelids,
displacement of eyeball (proptosis),
restriction of ocular movement
– Visual acuity and color vision
examination
• Broad spectrum, high dose IV
antibiotics
– Ceftriaxone + Metronidazole
• NSAIDs
• Topical / oral nasal decongestants
• Mucolytics: Bromhexine, Ambroxol,
Guaphanesin
Medical Treatment
Surgical Treatment
• For sinusitis
– Frontal sinus trephination
– External fronto-ethmoidectomy
(Lynch Howarth)
– Functional Endoscopic Sinus Surgery
( FESS)
• For orbital complications
– Sub-periosteal abscess drainage
Intra-cranial
complications
• 2nd
most common complication of sinusitis
• Most common in adolescents & young
adults (diploic venous system at peak
vascularity)
• Frontal sinus most commonly implicated
→ Ethmoid → Sphenoid → Maxillary
• Commonest route of spread
– Retrograde thrombophlebitis via
Introduction
Intra-cranial
complications
Clinical Features
• Fever
• Deep-seated headache
• Nausea & projectile vomiting
• Neck stiffness
• Seizures
• Altered sensorium & mood changes
• Late: bradycardia / hypotension /
stupor
Frontal lobe abscess
Investigations and Medical
Treatment
• Neurosurgery consultation
• CT scan PNS + brain with contrast
• MRI with contrast: investigation of
choice
• High dose broad spectrum I.V.
antibiotics: Ceftriaxone & Metronidazole
for 4-6 week
Surgical treatment for
abscess• For sinuses:
– Frontal trephination
– External fronto-ethmoidectomy (Lynch
Howarth)
– Functional Endoscopic Sinus Surgery
• For intra-cranial complication: by
Neurosurgeon
Mucocoele of
P.N.S.
Introduction
• Definition: epithelium lined, mucus filled
sac filling the paranasal sinus that is
capable of expansion
• Incidence:
– Frontal : 65 %
– Ethmoid : 25 %
– Maxillary : 10 %
– Sphenoid : rare
• Chronic obstruction of sinus ostium
with retention of normal sinus
mucus within sinus cavity
• Mucous retention cyst : Develops
from obstruction of ducts of sero
mucinous glands within sinus
Etiology
• Cystic, non-tender swelling above inner
canthus with egg-shell crackling
sensation on palpation
• Proptosis:
– Frontal : downward + forward +
lateral
– Ethmoid : forward + lateral
– Maxillary : up + forward
Clinical Features
Fronto-ethmoid mucocele
Investigations
– X-ray PNS OM view: expanded frontal
sinus, loss of scalloped margins,
translucency, depression or erosion of
supra-orbital ridge
– CT scan: homogenous smooth walled
mass expanding the sinus with thinning
of bone
Fronto-ethmoid
mucocele
Fronto-ethmoid mucocoele with
proptosis
Sphenoid mucocoele
1. Antibiotics and nasal
decongestants
2. External fronto-ethmoidectomy by
Lynch – Howarth’s approach
3. Endoscopic fronto-ethmoidectomy
4. Endoscopic decompression
(marsupialization)
Treatment
Lt. Ethmoid mucocoele
Drainage +
Marsupialization
Post-op CT scan
(coronal)
Frontal pyocele + fistula
Osteoplastic flap procedure for
frontal sinus mucocele
Pott’s puffy tumour
• Frontal sinus osteomyelitis (Percival
Pott, 1760)
• Fluctuant swelling over forehead
anteriorly
• May spread posteriorly leading to
subdural abscess
• Treatment
– Six week course of broad spectrum
Pott’s puffy tumour
Oro-antral fistula
• Fistulous tract
communicating
between oral cavity and
maxillary antrum
• Treatment : closure by
– Buccal mucosal
advancement flap
– Palatal flap
– Buccal fat pad flap
Toxic shock syndrome
• Rare, potentially fatal complication of
sinusitis
• Septicemia due to Staphylococcus
aureus or Streptococcus infection
• C/F:
– Fever, hypotension, skin rashes with
desquamation, multi-system failure
• Treatment
– IV Ceftriaxone 1g TDS

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Complications of sinusitis

  • 2. Definition • Progress of infection beyond the muco- periosteal lining of paranasal sinuses to involve the bone and neighboring structures (orbit, intra-cranial cavity, dentition) • Compromise in function of any part of
  • 3. Etiology • Weak immune response of host – Young children and immuno -compromised adults • Inadequate / inefficient treatment • Infection by highly virulent organisms • Abnormalities of muco- cilliary clearance
  • 4. Routes of infection • Via thin bones eg. lamina papyracea • Through natural suture lines • Through natural canal: infra-orbital canal • Retrograde thrombophlebitis: diploic vein of Breschet • Closely related roots of upper 2nd premolar & 1st molar teeth
  • 5. Classification • Acute – Local •Orbital •Intracranial •Bony •Dental – Distant •Toxic shock syndrome • Chronic – Mucocele – Pyocele • Associated diseases (?) – Otitis media – Adeno -tonsillitis – Bronchiectasis
  • 6. Orbital Complications ( Chandler et al 1970) 1. Pre-septal cellulitis 2. Orbital cellulitis without abscess 3. Orbital cellulitis with extra/ sub- periosteal abscess 4. Orbital cellulitis with intra-periosteal abscess
  • 7. Intracranial Complications 1. Meningitis 2. Encephalitis 3. Extra-dural abscess 4. Sub-dural abscess 5. Intra-cerebral abscess 6. Cavernous sinus thrombosis 7. Sagittal sinus thrombosis
  • 8. • Bony – Osteitis – Osteomyelitis (Pott’s puffy tumour) • Dental − Dental abscess − Oro-antral fistula
  • 9. • Commonest complication of sinusitis  • Young people at high risk: 85% < 20 yrs age  • Ethmoid sinus most commonly implicated → Frontal → Sphenoid → Maxillary  • Left orbit more commonly involved (?) Orbital complications
  • 10.
  • 11. Pre-septal cellulitis • Inflammation external to orbital septum • Edema of eyelids: – Upper lid : frontal sinusitis – Lower lid : maxillary sinusitis – Both lids : ethmoid sinusitis • No tenderness , visual loss , limitation of extra-ocular movement
  • 12.
  • 13. Orbital Cellulitis without abscess • Inflammation of adipose tissue deep to peri-orbital septum without suppuration • Diffuse peri -orbital edema with erythema • Mild proptosis • No restriction of extra-ocular movement • No change in vision
  • 14.
  • 15. Extra-periosteal abscess • Most common form of orbital cellulitis • Localized extra-periosteal pus collection • Mild proptosis, restriction of extra-ocular movement , vision loss • Color vision affected first – Red = brown – Blue = black
  • 17. Orbital cellulitis with Intra- periosteal abscess • Mild chemosis (edema of conjunctiva) • Proptosis: severe, asymmetric, quadrantic – Frontal sinusitis : down + forward + lateral – Ethmoid sinusitis : forward + lateral – Maxillary sinusitis : up + forward • Concurrent and complete
  • 19. Cavernous Sinus Thrombosis • Rapid onset, hectic fever • Bilateral orbital pain + severe chemosis • Bilateral absent pupillary reflex • Bilateral symmetrical axial proptosis • Sequential ophthalmoplegia (VI → III → IV) • Papilledema + loss of vision • Painful paresthesia of V1, V2
  • 21. B/L chemosis + proptosis
  • 22. Cavernous sinus Thrombosis Orbital abscess Bilateral Unilateral Rapidly progressive Slowly progressive Hectic fever Low grade fever Severe chemosis Mild chemosis Paraesthesia of V1, V2 No paraesthesia Sequential ophthalmoplegia Concurrent pan- ophthalmoplegia Symmetric axial proptosis Asymmetric quadrantic
  • 23. Evaluation of orbital complication • Ophthalmology consultation – Look for edema of eyelids, displacement of eyeball (proptosis), restriction of ocular movement – Visual acuity and color vision examination
  • 24. • Broad spectrum, high dose IV antibiotics – Ceftriaxone + Metronidazole • NSAIDs • Topical / oral nasal decongestants • Mucolytics: Bromhexine, Ambroxol, Guaphanesin Medical Treatment
  • 25. Surgical Treatment • For sinusitis – Frontal sinus trephination – External fronto-ethmoidectomy (Lynch Howarth) – Functional Endoscopic Sinus Surgery ( FESS) • For orbital complications – Sub-periosteal abscess drainage
  • 27. • 2nd most common complication of sinusitis • Most common in adolescents & young adults (diploic venous system at peak vascularity) • Frontal sinus most commonly implicated → Ethmoid → Sphenoid → Maxillary • Commonest route of spread – Retrograde thrombophlebitis via Introduction
  • 29. Clinical Features • Fever • Deep-seated headache • Nausea & projectile vomiting • Neck stiffness • Seizures • Altered sensorium & mood changes • Late: bradycardia / hypotension / stupor
  • 31. Investigations and Medical Treatment • Neurosurgery consultation • CT scan PNS + brain with contrast • MRI with contrast: investigation of choice • High dose broad spectrum I.V. antibiotics: Ceftriaxone & Metronidazole for 4-6 week
  • 32. Surgical treatment for abscess• For sinuses: – Frontal trephination – External fronto-ethmoidectomy (Lynch Howarth) – Functional Endoscopic Sinus Surgery • For intra-cranial complication: by Neurosurgeon
  • 34. Introduction • Definition: epithelium lined, mucus filled sac filling the paranasal sinus that is capable of expansion • Incidence: – Frontal : 65 % – Ethmoid : 25 % – Maxillary : 10 % – Sphenoid : rare
  • 35. • Chronic obstruction of sinus ostium with retention of normal sinus mucus within sinus cavity • Mucous retention cyst : Develops from obstruction of ducts of sero mucinous glands within sinus Etiology
  • 36. • Cystic, non-tender swelling above inner canthus with egg-shell crackling sensation on palpation • Proptosis: – Frontal : downward + forward + lateral – Ethmoid : forward + lateral – Maxillary : up + forward Clinical Features
  • 38. Investigations – X-ray PNS OM view: expanded frontal sinus, loss of scalloped margins, translucency, depression or erosion of supra-orbital ridge – CT scan: homogenous smooth walled mass expanding the sinus with thinning of bone
  • 42. 1. Antibiotics and nasal decongestants 2. External fronto-ethmoidectomy by Lynch – Howarth’s approach 3. Endoscopic fronto-ethmoidectomy 4. Endoscopic decompression (marsupialization) Treatment
  • 45. Frontal pyocele + fistula
  • 46. Osteoplastic flap procedure for frontal sinus mucocele
  • 47. Pott’s puffy tumour • Frontal sinus osteomyelitis (Percival Pott, 1760) • Fluctuant swelling over forehead anteriorly • May spread posteriorly leading to subdural abscess • Treatment – Six week course of broad spectrum
  • 49. Oro-antral fistula • Fistulous tract communicating between oral cavity and maxillary antrum • Treatment : closure by – Buccal mucosal advancement flap – Palatal flap – Buccal fat pad flap
  • 50.
  • 51. Toxic shock syndrome • Rare, potentially fatal complication of sinusitis • Septicemia due to Staphylococcus aureus or Streptococcus infection • C/F: – Fever, hypotension, skin rashes with desquamation, multi-system failure • Treatment – IV Ceftriaxone 1g TDS