During the Enlightenment period in Europe, influential thinkers used reason and their writings to challenge the status quo and advocate for political and social change. Some of the major Enlightenment thinkers discussed include Voltaire, Montesquieu, Rousseau, Beccaria, Wollstonecraft, Hobbes, and Locke. They addressed issues like separation of powers, individual rights, criminal justice reform, women's rights, forms of government, and the social contract between governments and citizens.