During the 4th week of human development, the neural tube is formed and pharyngeal arches begin to develop, giving rise to structures like the maxilla and mandible. Organs like the upper limb buds, forebrain, otic pits, and lens placodes also begin to form. In the 5th week, the head grows significantly while structures like the mesonephric ridge and cervical sinus develop. By the 6th week, the heart begins beating regularly and neural tubes close as arm buds and a tail become visible. Intestines also begin to develop during this period.

1. 4th to 8th week of human
development
BY. JAY KATHIRIYA

2. 4th week
• In the 4th week, Neural tube is formed
• Rostral and caudal neuropores
• Pharyngeal arches are formed
o maxilla
o mandible
• Organs which develops in this week are :
o Upper limb buds
o Forebrain
o Otic pits
o Lens placods
o Caudal eminance

3. 4th week

4. 5th week
• Minor changes in body forms
• Head grows the most
• 2nd pharyngeal arch forms
ocervical sinus on both sides
• Mesonephric ridge forms
omesonephric kidneys - excretory organs

5. 5th week

6. 6th week
• Heart starts beating in regular rhythm
• Neural tubes are closed
• Arm buds and tail are visible
• Hepatic plates appear
• Anterior and posterior horns differentiate in the spinal cord
• Intestines deveops

7. 6th week

8. 7th week
• Fingers develop
• Omphaloenteric duct
• communication between primordial gut and umbilical vesicle
• Ossification of bones start in upper limbs

9. 7th week

10. 8th week
• At this week embryo has taken on recognizable human shape
• From this point, it is referred to as foetus
• Foetus continuous to grow
• No new organs are formed from this stage

11. 8th week

12. References
• http://www.sharinginhealth.ca/biology/development_weeks_04-08.html
• http://www.duhs.edu.pk/curriculum/downloads/lec2-sem1-FMWK7-
20140207.pdf
• http://my.clevelandclinic.org/health/articles/fetal-development-stages-of-
growth