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Gallium-67 citrate scintigraphy is preferred over In-111 leukocyte scintigraphy for the detection of disk space infection. While both agents are sensitive for osteomyelitis, gallium-67 has been shown to be more sensitive for disc space infection compared to In-111 leukocyte imaging. This is due to potentially confusing normal bowel activity seen on gallium-67 scans that could obscure abdominal pathology. In-111 leukocyte imaging is generally preferred for evaluating other infectious/inflammatory conditions like abdominal abscesses and infected joint prostheses due to less potential for false positives from normal biodistribution.
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