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- Echogenic intracardiac focus is most commonly seen as a normal variant on prenatal ultrasound but should prompt careful examination for other abnormalities. - While it represents a normal variant, echogenic intracardiac focus has been associated with trisomy 13 and 21 but not trisomy 18. - The majority (90%) of echogenic intracardiac foci are located in the left ventricle, not the right ventricle as stated in one response option.
