CSIRO has conducted extensive research into automating heavy equipment used in mining operations. This includes developing technologies like dragline swing assist to automate parts of a dragline's operation, digital terrain mapping to aid operators, and autonomous systems for rope shovels, load haul dump vehicles, excavators, and explosive loading. CSIRO is currently working on projects involving automated draglines, wireless sensor networks, and automation of other mining equipment. The research aims to improve safety and productivity through autonomous technologies.
Francesco Benvenuto (Space1): Shaping the Field Technician of the Future with MRAugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Francesco Benvenuto (Space1): Shaping the Field Technician of the Future with MR
By 2020, more than 75% of large Field Service organizations will deploy mobile solutions that go beyond optimization processes, and add capabilities that help technicians improve their performance. Amongst the technologies that will take part of this digital transformation, X Reality is the one that will open new frontiers for Maintenance Processes.
http://AugmentedWorldExpo.com
Harald Wuest (Visometry): Why Model Tracking is the Future of Industrial AR!AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Harald Wuest (Visometry): Why Model Tracking is the Future of Industrial AR!
Relying on CAD-data for object tracking is not a pain, but a huge gain for the tracking robustness and also for an easy setup process. We demonstrate some typical service and maintenance applications and show how model-based tracking techniques can be applied.
http://AugmentedWorldExpo.com
Sascha Goldner (Airbus Defence and Space): A Case-Study for a UAV Operator En...AugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Sascha Goldner (Airbus Defence and Space): A Case-Study for a UAV Operator Environment Based on Mixed Reality
How can a consumer technology like VR/AR “rolled out” in a traditional and in some aspects even conservative company like Airbus Defence and Space? Beside of answering this question, a case-study shall be presented in which Mixed Reality is used in order to provide an enhanced and very isolated environment for a UAV operator.
http://AugmentedWorldExpo.com
Francesco Benvenuto (Space1): Shaping the Field Technician of the Future with MRAugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Francesco Benvenuto (Space1): Shaping the Field Technician of the Future with MR
By 2020, more than 75% of large Field Service organizations will deploy mobile solutions that go beyond optimization processes, and add capabilities that help technicians improve their performance. Amongst the technologies that will take part of this digital transformation, X Reality is the one that will open new frontiers for Maintenance Processes.
http://AugmentedWorldExpo.com
Harald Wuest (Visometry): Why Model Tracking is the Future of Industrial AR!AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Harald Wuest (Visometry): Why Model Tracking is the Future of Industrial AR!
Relying on CAD-data for object tracking is not a pain, but a huge gain for the tracking robustness and also for an easy setup process. We demonstrate some typical service and maintenance applications and show how model-based tracking techniques can be applied.
http://AugmentedWorldExpo.com
Sascha Goldner (Airbus Defence and Space): A Case-Study for a UAV Operator En...AugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Sascha Goldner (Airbus Defence and Space): A Case-Study for a UAV Operator Environment Based on Mixed Reality
How can a consumer technology like VR/AR “rolled out” in a traditional and in some aspects even conservative company like Airbus Defence and Space? Beside of answering this question, a case-study shall be presented in which Mixed Reality is used in order to provide an enhanced and very isolated environment for a UAV operator.
http://AugmentedWorldExpo.com
Dr. Jian Liang (HiScene): AR for Industry in China: From Concepts to Real App...AugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Dr. Jian Liang (HiScene): AR for Industry in China: From Concepts to Real Applications
AI/AR industry has attracted attention never seen before of academia and industry, into which numerous talents and resources have been invested. This talk will share with you some difficulties, misconceptions and experience in commercializing AR based on HiScene’s practice.
http://AugmentedWorldExpo.com
Hiren Bhinde (Qualcomm Technologies): Unlocking the Mysteries of SLAM (simult...AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Hiren Bhinde (Qualcomm Technologies): Unlocking the Mysteries of SLAM (simultaneous localization & mapping)
Qualcomm will be presenting a tutorial on XR technologies.
http://AugmentedWorldExpo.com
Quantified Social und das Internet der DingeWerner Keil
Quantified Self, das Verfahren der Messung, Protokollierung und in der Regel mit anderen geteilte Metriken um Gesundheit und Fitness über einen gewissen Zeitraum, durch Verwendung mindestens eines Sensors. Zur Förderung eines gesünderen Lebensstils um fit zu bleiben oder Gewicht zu verlieren.
Andere Anwendungsfälle sind Messung von Blutzuckerspiegel, Puls oder Herzfrequenz die Grenzen zwischen Freizeit/Fitness und Gesundheitswesen sind hier oft fließend.
Sobald die Daten gesammelt, übertragen und verarbeitet wurden, stehen sie in einer Sensor-Datenplattform ("Sensor Web") zur Nutzung durch Anwendungen in Echtzeit bereit, entweder direkt in einer Web-Anwendung oder über ein API. Dies bildet eine neue Kategorie von Web-Services die Datenströme aus verschiedenen IoT Sensoren und Messgeräten mit Web-Streams oder Social-Networking-Aktivitäten verbindet.
Das daraus resultierende Paradigma, mit dem Namen Social Internet of Things (SIoT), hat ein großes Potenzial, um neue Anwendungen für Mensch und Maschine zu Maschine (M2M) Konnektivität hervorzubringen.
Diese Session gibt einen Überblick über populäre Datenplattformen, APIs, Fitness und IoT Gemeinschaften sowie eine Live-Demo ausgewählter Geräte.
Wearable Photogrammetry - What to Wear for Work #COMIT2017Comit Projects Ltd
Presentation by Stuart Young at the 2017 COMIT Annual Conference 'Mobilising Digital Assets', to be held at The Building Centre in London on Wednesday 24th and Thursday 25th of May 2017. More information: http://www.comit.org.uk/live-blog-comit2017
Social Media Week 2015 - Quantified Self and the Social Internet of ThingsWerner Keil
The Quantified Self, the process of measuring, logging and usually sharing metrics related to your health and fitness over a period of time, in most cases, by using one or more sensing devices. Aiming for behavioural change like staying fit or losing weight.
Other use cases include tracking blood sugar levels, pulse or heart rate blurring the boundaries between recreational fitness and healthcare.
Once data has been collected, transmitted, and processed, it can be brought into a Sensor data platform (also called "Sensor Web") for making applications from real-time data sources, either directly or via API. This forms a new category of web service to integrate data flows from different IOT quantified sensor devices, web services, and social networking activity.
The resulting paradigm, named Social Internet of Things (SIoT), has great potential to support novel applications for Human and Machine to Machine (M2M) Connectivity.
This session provides an overview of popular data platforms, APIs, fitness and IoT Communities plus a live demo of selected devices by the audience.
Junli Gu at AI Frontiers: Autonomous Driving RevolutionAI Frontiers
Autonomous driving has gain enormous attention and momentum in the past year, due to its potential huge impact on car industry. Junli Gu's talk summarizes the current trends and on-going efforts of driver-less cars. Her talk highlights the technical challenges and share some insights in how machine learning might lead us to the path.
Khaled Sarayeddine (Optinvent): Optical Technologies & Challenges for Next Ge...AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Khaled Sarayeddine (Optinvent): Optical Technologies & Challenges for Next Generation AR
The talk will describe the current status on key optical technologies and ongoing development to meet Small footprint & Large FOV High resolution Display, as well to accommodate Light field feature.
http://AugmentedWorldExpo.com
Mining Matters Core Concepts are standalone classroom ready activities that reflect key foundational ideas in Earth science. Sourced from our archives of curriculum-linked teacher resources, each activity reflects an integral part of many important concepts and theories in the various disciplines that comprise the Geosciences.
In an effort to be of service to all of our teacher-partners, these activities have been assembled as a way to support individual teachers without the need to attend a pre-requisite teacher training workshop. All the contents of the Core Concepts resource support current teaching practices that values hands-on experience where students take an active role in learning. Any rocks and minerals samples as well as print resources required for successful classroom delivery can be sourced through Mining Matters.
Overview of key industry challenges and ABB’s vision & best-practice approaches for:
- Evaluating reserves and mine schedules
- Tracking and optimizing mined product
- Optimizing work of equipment and people
MINE LIFE CYCLE; LIFE CYCLE OF DEPOSITS; LIFE-CYCLE OF A MINE PROJECT; STAGES IN THE LIFE CYCLE OF A MINE PROJECT; Prospecting; Exploration ; 3D modeling software's for mining sectors; Mineral Resource; Mineral Reserve; Development; Exploitation ; MINE PLANNING CYCLE ; Reclamation; ENVIRONMENTAL IMPACTS OF NONRENEWABLE MINERAL RESOURCES; SOURCES OF METAL POLLUTION; Harmful Environmental Effects of Mining; Persistent, Bio-accumulative and Toxi (PBT ); Lead; Mercury; Cadmium; Arsenic
Dr. Jian Liang (HiScene): AR for Industry in China: From Concepts to Real App...AugmentedWorldExpo
A talk from the Work Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Dr. Jian Liang (HiScene): AR for Industry in China: From Concepts to Real Applications
AI/AR industry has attracted attention never seen before of academia and industry, into which numerous talents and resources have been invested. This talk will share with you some difficulties, misconceptions and experience in commercializing AR based on HiScene’s practice.
http://AugmentedWorldExpo.com
Hiren Bhinde (Qualcomm Technologies): Unlocking the Mysteries of SLAM (simult...AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Hiren Bhinde (Qualcomm Technologies): Unlocking the Mysteries of SLAM (simultaneous localization & mapping)
Qualcomm will be presenting a tutorial on XR technologies.
http://AugmentedWorldExpo.com
Quantified Social und das Internet der DingeWerner Keil
Quantified Self, das Verfahren der Messung, Protokollierung und in der Regel mit anderen geteilte Metriken um Gesundheit und Fitness über einen gewissen Zeitraum, durch Verwendung mindestens eines Sensors. Zur Förderung eines gesünderen Lebensstils um fit zu bleiben oder Gewicht zu verlieren.
Andere Anwendungsfälle sind Messung von Blutzuckerspiegel, Puls oder Herzfrequenz die Grenzen zwischen Freizeit/Fitness und Gesundheitswesen sind hier oft fließend.
Sobald die Daten gesammelt, übertragen und verarbeitet wurden, stehen sie in einer Sensor-Datenplattform ("Sensor Web") zur Nutzung durch Anwendungen in Echtzeit bereit, entweder direkt in einer Web-Anwendung oder über ein API. Dies bildet eine neue Kategorie von Web-Services die Datenströme aus verschiedenen IoT Sensoren und Messgeräten mit Web-Streams oder Social-Networking-Aktivitäten verbindet.
Das daraus resultierende Paradigma, mit dem Namen Social Internet of Things (SIoT), hat ein großes Potenzial, um neue Anwendungen für Mensch und Maschine zu Maschine (M2M) Konnektivität hervorzubringen.
Diese Session gibt einen Überblick über populäre Datenplattformen, APIs, Fitness und IoT Gemeinschaften sowie eine Live-Demo ausgewählter Geräte.
Wearable Photogrammetry - What to Wear for Work #COMIT2017Comit Projects Ltd
Presentation by Stuart Young at the 2017 COMIT Annual Conference 'Mobilising Digital Assets', to be held at The Building Centre in London on Wednesday 24th and Thursday 25th of May 2017. More information: http://www.comit.org.uk/live-blog-comit2017
Social Media Week 2015 - Quantified Self and the Social Internet of ThingsWerner Keil
The Quantified Self, the process of measuring, logging and usually sharing metrics related to your health and fitness over a period of time, in most cases, by using one or more sensing devices. Aiming for behavioural change like staying fit or losing weight.
Other use cases include tracking blood sugar levels, pulse or heart rate blurring the boundaries between recreational fitness and healthcare.
Once data has been collected, transmitted, and processed, it can be brought into a Sensor data platform (also called "Sensor Web") for making applications from real-time data sources, either directly or via API. This forms a new category of web service to integrate data flows from different IOT quantified sensor devices, web services, and social networking activity.
The resulting paradigm, named Social Internet of Things (SIoT), has great potential to support novel applications for Human and Machine to Machine (M2M) Connectivity.
This session provides an overview of popular data platforms, APIs, fitness and IoT Communities plus a live demo of selected devices by the audience.
Junli Gu at AI Frontiers: Autonomous Driving RevolutionAI Frontiers
Autonomous driving has gain enormous attention and momentum in the past year, due to its potential huge impact on car industry. Junli Gu's talk summarizes the current trends and on-going efforts of driver-less cars. Her talk highlights the technical challenges and share some insights in how machine learning might lead us to the path.
Khaled Sarayeddine (Optinvent): Optical Technologies & Challenges for Next Ge...AugmentedWorldExpo
A talk from the Develop Track at AWE USA 2018 - the World's #1 XR Conference & Expo in Santa Clara, California May 30- June 1, 2018.
Khaled Sarayeddine (Optinvent): Optical Technologies & Challenges for Next Generation AR
The talk will describe the current status on key optical technologies and ongoing development to meet Small footprint & Large FOV High resolution Display, as well to accommodate Light field feature.
http://AugmentedWorldExpo.com
Mining Matters Core Concepts are standalone classroom ready activities that reflect key foundational ideas in Earth science. Sourced from our archives of curriculum-linked teacher resources, each activity reflects an integral part of many important concepts and theories in the various disciplines that comprise the Geosciences.
In an effort to be of service to all of our teacher-partners, these activities have been assembled as a way to support individual teachers without the need to attend a pre-requisite teacher training workshop. All the contents of the Core Concepts resource support current teaching practices that values hands-on experience where students take an active role in learning. Any rocks and minerals samples as well as print resources required for successful classroom delivery can be sourced through Mining Matters.
Overview of key industry challenges and ABB’s vision & best-practice approaches for:
- Evaluating reserves and mine schedules
- Tracking and optimizing mined product
- Optimizing work of equipment and people
MINE LIFE CYCLE; LIFE CYCLE OF DEPOSITS; LIFE-CYCLE OF A MINE PROJECT; STAGES IN THE LIFE CYCLE OF A MINE PROJECT; Prospecting; Exploration ; 3D modeling software's for mining sectors; Mineral Resource; Mineral Reserve; Development; Exploitation ; MINE PLANNING CYCLE ; Reclamation; ENVIRONMENTAL IMPACTS OF NONRENEWABLE MINERAL RESOURCES; SOURCES OF METAL POLLUTION; Harmful Environmental Effects of Mining; Persistent, Bio-accumulative and Toxi (PBT ); Lead; Mercury; Cadmium; Arsenic
The aim of “BLUESLEMON” project is to develop a low-cost automatic system for monitoring landslide surface displacement using drones and BT beacons. The proposed drone architecture is developed to go beyond the current state-of-the-art techniques and is characterized by autonomous navigation capabilities. The UAV platform is equipped with obstacle-detection sensors and collision-avoidance algorithms, allowing the smart UAS to be easily employed for autonomous navigation, even in case of diverse environments or applications (search-and-rescue operations in alpine environments or automatic surveillance in urban areas).
This project aims a swarm behaviour of multiple robots operating indoor in a closed formation. An on-board computation is used for localization and to get linear control of the robots. The entire task is performed indoor, performing distinct trajectories assigned to individual or group of robots. In our project we showed several estimation techniques which increase the robust tracking of trajectories. External localization is obtained to get the position of robots with the help of webcam. MILP algorithm or convex optimization is used to generate a complex trajectory that is performed by the distinct robots. We performed various trajectories, as an example to show the agility of micro robots tracking complex paths and avoiding stationary obstacles.
A presentation by Michael Xinogalos, Surveying Engineer NTUA 1988, Technical Director of ASTROLABE ENGINEERING at 3rd Annual Optech Users Meeting - Rome 2007 (www.astrolabe.gr - www.laseraction.eu)
Autonomous car based on artificial intelligence which is used by google for replacing drivers in car. Which will leads to the driving into the next phase
Ilris vs lynx highway surveying and data post processing - munich2008Michael Xinogalos
A presentation by Michael Xinogalos, Surveying Engineer NTUA 1988, Technical Director of ASTROLABE ENGINEERING at 4th International Terrestrial Laser Scanning Users Meeting - Munich 2008 (www.astrolabe.gr - www.laseraction.eu)
Real time path planning based on hybrid vanet enhanced transportation systemIISTech2015
Real time path planning based on hybrid vanet enhanced transportation system || 2015-2016 IEEE NS2 Projects Training
Contact: IIS TECHNOLOGIES
ph:9952077540,landline:044 42637391
mail:info@iistechnologies.in
AI and Space: finally, no more arguing with the GPSSpeck&Tech
ABSTRACT: This talk will be about how AIKO is revolutionizing how space missions are operated, thanks to the use of Artificial Intelligence both on-board the spacecraft and on-ground, in the mission control centers. AI is posed to be one of the game-changers of the space industry, helping to achieve more scalable, profitable missions that deliver more relevant and usable data. AIKO is leading this race for the adoption of AI in space, and during this talk, we’ll cover some of the crazy things we are doing in the company.
BIO: Mattia Varile, Chief Innovation Officer (CIO). Mattia's primary role involves investigating and testing innovative technologies applied to automation for the space sector. He earned his degree in Aerospace Engineering from Politecnico di Torino and gained valuable experience working as a systems engineer with the CubeSat Team Polito. Since 2018, Mattia has been an active member of AIKO, where he has honed his expertise in Artificial Intelligence, specifically in Deep Learning and Reinforcement Learning. Prior to his current role, Mattia participated in several research projects and startup initiatives.
3D Scanners and their Economic FeasibilityJeffrey Funk
These slides use concepts from my (Jeff Funk) course entitled analyzing hi-tech opportunities to analyze how the economic feasibility of 3D scanners is becoming better through improvements in lasers, camera ICs, and processor ICs. 3D scanning is both a complement to 3D printing and a technology with its own unique applications. 3D printing of complex objects can be done from a CAD database or from a 3D scan where a 3D scan can be done with laser or other sources of white light such as LEDs.
3D scanning can also be done for other purposes. For example, scientists and engineers are using 3D scanners to survey archeological, construction, crime scene, and engineering sites, to document maintenance and repair of engineered systems, and to customize medical and dental products for humans. Improvements in lasers, LEDs, camera chips, ICs, and other components continue to improve the economic feasibility of 3D scanning. Longer wavelength lasers increase the scanning range, better camera chips improve the scanning resolution, and better lasers, camera chips, and processor ICs reduce the scanning time. For example, third generation scanners from Argon, one leading supplier, have 100 times higher resolution and one tenth the scan times of Argon’s first generation system.
For costs, lasers make up the largest percentage followed by camera and processor ICs. For example, lasers make up 80% of the hardware cost for one high-end system with a current cost of $1346 and a price of about $3000. As laser costs fall and as volumes enable smaller margins, the price of such systems will fall.
For the same reasons, low-end systems continue to emerge. These include Microsoft’s Kinect and an app for the iPhone. Microsoft’s Kinect was $150 while the app was only $4.99, both in early 2013. As such low-end systems proliferate, and high-end systems continue to get cheaper, 3D scanning will find new applications.
Smart City/Operation Management -Gazi Sanaul Hasan Gazi Sanaul Hasan
A smart city is an urban area that uses different types of electronic data collection sensors to supply information which is used to manage assets and resources efficiently.This includes data collected from citizens, devices, and assets that is processed and analyzed to monitor and manage traffic and transportation systems, power plants, water supply networks, waste management, law enforcement, information systems, schools, libraries, hospitals, and other community services.
Presentation for ED Toolbox “Future of Work, Innovation Pathways and Climate Change Initiatives” project at the Precinct, Level 2, 315, Brunswick St, Fortitude Valley, 4006 on Tuesday, February 25th at 2.30-4.30pm.
Here are the videos: https://www.youtube.com/watch?v=fivY-ZlO1vI&feature=emb_logo
and https://vimeo.com/368704905
Opportunities & Challenges: Policy, Workforce, Ethics, Design, Safety Standards & Public Acceptance. Outcome of this session – non technical factors - identify what policy, ethics etc need to be addressed to reach the vision, education
What is the reason why there is no collaboration
What are the legislation/financial/ incentives – share value arrangement (platform technologies – ROI, VP, IP)
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
2. www.ict.csiro.au
Projects, Past Present and Future
Sensor Networks
for Coal Prep plants
ACARP C11009 (03-04)
Open Cut Automation
ACARP C11054
Traffic Management
Truck path planning
ACARP C13041 (2004-05)
Excavator Guidance
Laser based measurement
ACARP C14043 (2005-06)
Dragline Swing Assist
Algorithm Refinement
ACARP C13040 (04-05)
Digital Terrain Mapping
Calibration and Integration
ACARP C13034 (2004-05)
Rope Shovel Automation
Auto digging on scale model
ACARP C12030 (2003-04)
Trayscan
Truck Load Volume
Transcale ((2000-2004)
Automated LHD's
Commercial Prototype
AMIRA/Caterpillar (99-03)
Automated Explosive Loading
Proof-of-Concept
ORICA (2000-01)
Shovel Dipper Volume
Laser Scanning Feasibility
BHP (1998)
Automated Haulage
GPS and INS guidance
Komatsu & Caterpillar
Dragline Swing Assist
Feasibility demonstration
ACARP C5003 (1996-98)
Digital Terrain Mapping
Proof-of Concept
ACARP C10039 (2001-02)
Dragline Swing Assist
ACIRL Scale Model
ACARP ME3 (1994-95)
Dragline Swing Assist
Production field trials
ACARP C9028 (2001-02)
Automated Explosive Loading
Commercial Prototype
ORICA (2005-)
Rope Shovel Automation
On production shovel
ACARP proposal
Shovel Force Feedback
Based upon DTM and performance
ACARP proposal
Boom Monitoring
Wireless sensor network
ACARP
Automated Dragline
Integration of DSA with DTM
ACARP proposal
Wireless Sensor Network
for Mine Environment
ACARP proposal
ELAP
Prototype
ORICA (2002)
Automated Explosive Loading
Feasibility Study - Vision and Laser
Scanning ORICA (1998-99)
Rope Shovel Automation
Auto loading / face mapping
ACARP C14058 (2005-06)
Surface Mining
Completed
Commercialized
Current
Proposed
HMC Automation
Auto Tramming
Alcoa (2005-06)
Software development
RTX & DDX
Hardware development
IMU & IMU
3. www.ict.csiro.au
Dragline Swing Assist (DSA)
• Since 1994 we have been automating a large part (80%) of a
dragline’s cycle (swing, dump and return).
• We have installed two systems on production machines
• In 2003 we ran a two-week production trial on the BE1350
• This work has been supported by five ACARP projects
Optimized swing path
4. www.ict.csiro.au
Dragline Digital Terrain Maps (DTM)Dragline Digital Terrain Maps (DTM)
We have installed a protype system on a BE1350
dragline at Boundary Hill (Callide)
It assists the operator in excavating to specific bench
heights with increased precision and confidence.
It displays a high resolution image of spoil pile and
the surrounding terrain.
DTM can also guides the operator in correct
movement and positioning of the dragline tub.
This work has been supported by two ACARP
projects
5. www.ict.csiro.au
DTM MasterplanDTM Masterplan
OverviewOverview
Images include
cross-section,
plan view or 3D.
Operator
prompts include
a tub positioning
reference and
critical dig lines
The elevation image is shown.
Plan package will also utilise
colours and effects to highlight
variations between the dig and
actual plan
6. www.ict.csiro.au
DTM – Direct Operator Benefits…DTM – Direct Operator Benefits…
It visually prompts the operator where to dig and dump
overburden as per the dig plan.
Masterplan clearly and immediately highlights
variations between the actual dig and the planned
excavation.
Greatly aids in reducing excessive rehandle.
It assists the operator in excavating to specific bench
heights with increased precision and confidence.
It displays a high resolution image of spoil pile and the
surrounding terrain.
DTM can also guides the operator in correct
movement and positioning of the dragline tub.
7. www.ict.csiro.au
Rope Shovel Automation (RSA)
Automation of these machines could lead to significant productivity
improvements
In 2003/04 we demonstrated autonomous digging on a scale model
(1/7 th) machine (this work was supported by ACARP)
We are now running a second ACARP project to further progress the
system and autonomously dump into trucks (scale model)
8. www.ict.csiro.au
Shovel Traffic Control
A combination of sensors will:
• Generate a DTM of the
local environment
• Enable the swing loader to
locate each haul truck as it
approaches
• Provide communication
from the swing loader to
each haul truck
Develop a system which schedules and directs haul truck drivers
to an optimum loading position for a swing loader.
Develop a system which schedules and directs haul truck drivers
to an optimum loading position for a swing loader.
Handover
Zone
Work Zone
Incoming
Trucks
Outgoing
Trucks
Bench
Obstacle
10. www.ict.csiro.au
Truck Volume Measurement (Trayscan)Truck Volume Measurement (Trayscan)
Trayscan is an automated system that measures the volume of
material in the tray of haul-trucks using laser-scanning technology.
This technology provides the ability to measure the volume in-situ,
whilst the truck is moving. Commercialised through Transcale.
A 3D profile is
generated, as the
haul truck drives
under scanning
laser.
The in-situ volume
is estimated from a
comparison of
empty and full
trucks.
11. www.ict.csiro.au
Load Haul Dump (LHD) Automation
Demonstrated full speed operation at NorthParkes Mine
System based upon reactive navigation requiring no guidance
infrastructure
Navigation technology licensed to DAS (CEPL) with commercial
system launched April 2003
Pre-production prototypes developed for a three type of LHD including
electric machines
Automated CSIRO loader tested at
Northparkes mine
Automated Tamrock electric LHD
from Northparkes at QCAT
12. www.ict.csiro.au
Automation of Explosive Charging (AOC)
We have developed a robotic charging unit to automatically charge
blast holes in underground metal mines (ORICA)
A scanning laser is used to create a 3D map in order to locate a ring of
blast holes
A vision system is used to guide a hose into the collar of each hole
13. www.ict.csiro.au
Autonomous Hot Metal Carrier
• 30 tonne vehicle for
navigation sensor
• moving molten
aluminium
• Demonstrate full
automation within the
next 6 months
• The vehicle is based on
a large fork-lift truck
• Will use laser scanners
as the primary
14. www.ict.csiro.au
Who are we ?
Team Complement
• 7.5 Research staff
• 4 Engineering support
– 2 engineers
– 2 technicans
• 1 BDM (theme resource)
• 1 Executive officer (theme
resource)
• 2 Postdocs
• 4 Co-supervised PhD
students
• Visitors (current)
– 1 IAESTE intern
– 5 undergraduate students
Disciplines/Skills
• Electrical engineering
• Mechanical engineering
• Computer Science
• Aerospace engineering
• Physics & Applied maths
15. www.ict.csiro.au
What we do?
The intelligent connection of perception to actionThe intelligent connection of perception to action
Robot navigation
Relative & reactive navigation
Visual homing
Visual servoing
Multiple cameras with sensor
fusion
Ranging and measurement
Laser imaging
3D imaging
Omni directional vision
Stereo vision
Agent based systems
Low-cost distributed sensor systems
Ad-hoc wireless networks
Real time computing
Distributed systems
Real time libraries
Embedded systems
High-performance control systems
Hydraulic
Electro mechanical
16. www.ict.csiro.au
Team Project Activities
External focus
Mining Robots
• Unique issues facing mining sector:
• Dirty, dusty, wet and hot
• Constantly changing environment (the aim of mining!)
Strategic Focus
Competent vision-based navigation and control,
• tested on our platforms: ground, air, underwater
Wireless sensor and actuator networks
• Robot interaction & Environmental monitoring
Deliver prototypes of complex engineered systems for non-
traditional robotics applications (field/outdoor robotics)
Deliver prototypes of complex engineered systems for non-
traditional robotics applications (field/outdoor robotics)
18. www.ict.csiro.au
Autonomous Land Vehicle
• Experimental platform for
land based navigation
• Based on a ride-on
lawnmower
• Equipped with vision, laser
scanner and magnetic
compass
• All computing on-board
19. www.ict.csiro.au
Autonomous Aerial Vehicles
Mark II – Mantis (2003)
Mark I (1999-2002)
• Experimental platform for testing CSIRO
autonomous flight control system
• Equipped with stereo vision, low-cost
inertial sensors, magnetic compass and
standard GPS
• All computing on-board
• We have developed a vision-based velocity
and height estimation system
• Currently investigating asset management
and search support opportunities.
20. www.ict.csiro.au
Cable-Array Robot
• A set of spatially distributed
motors which actuate cables
connected to an end effecter
– Similar to a Stewart platform
• By changing the length of the
cables, the end effecter can
be moved
• Examples include:
– SkyCam – used in football
stadiums for giving an
overhead view
– NIST robot crane
– Quay cranes
Schematic view of a cable-array robot
end effecter
actuator
cables
21. www.ict.csiro.au
Robotics & Sensor Networks
Old thinking New thinking
Robot
carries/controls small
number of expensive
sensors
Sensors are
everywhere, robot
asks for information
Scientists go into
field to gather data
Robot goes into field
to “harvest” data
from sensors
Robot goes into field
to gather data itself
27. www.ict.csiro.au
DDX: Distributed Data eXchange
Local store
C
P
C
C
CP
P
Local store
internet
Log file
• Real-time publish and subscribe model
• Shared memory within machine
• Time stamping
• Event handling & synchronization
• Multicast between machines
CPU2CPU1
Editor's Notes
Likely benefits might include:
1. Increased productivity. Open Cut Automation Scoping Study C11054 [1] reports that “truck spotting at 120 degree loader swing versus a 90 degree swing comes at a cost of 5% in BCM moved". There appears to be some anecdotal evidence that improvements to cycle time and filling efficiency can be made if the truck is optimally placed relative to the loader.
2. Reduced maintenance costs. Optimal placement of the truck relative to the loader will lead to reduced duty on both the loader and the truck. Shorter reach required from the loader will lead to lower internal stresses plus the ability to distribute the bucket contents more evenly across the tray of the truck
3. Improved safety. The potential for truck and truck swing loader collisions will be greatly reduced by the proposed system. The swing loader is now aware of the relative position of all vehicles in its vicinity and manages their movement to ensure safe, collision free operation.
others –camera’s, Chile, photogrametry – issues, calibration, lighting, feature reach,
dynamic.
Does not require calibration
Minor site preparation
Truck is scanned in motion
Acquisition of data is automated
Ruggerdized hardware
Operates in mining environment*
Eyesight – rebranded regal laser. Expensive and inaaprporiate use of tech. Requires stationary vehicle.