1. The document discusses lipid-lowering drugs and their role in treating atherosclerosis. 2. It describes the different classes of lipoproteins that transport lipids like cholesterol and triglycerides in the blood, and the two pathways through which lipid transport occurs. 3. Hyperlipidemias are conditions characterized by elevated plasma lipids and lipoproteins, which can result in cholesterol deposition in arterial plaques and other tissues, leading to diseases like atherosclerosis, heart attacks, and strokes. Primary hyperlipidemias have a genetic cause, while secondary ones result from other conditions.

1. Therapeutics of Cardiovascular Diseases Lipid-Lowering Drugs and Atherosclerosis 2008 George Hsiao Institute of Pharmacology, TMU

4. Structure of Lipoprotein Particles