4. 4
Thoracic Aorta
Definitions
Normal Dimensions
– Mid-descending 26-28 mm
Dilation (Ballooning, Bulging, Ectasia)
Aneurysm
– Types
• Saccular
• Fusiform
– Definition
• When the diameter exceeds 4 cm or diameter exceeds 1.5 times normal
Dissection
– Tear in vessel wall results in false lumen
– Types
• Type A – involves ascending aorta
• Type B – involves descending aorta
21. 21
Thoracic Aorta
Aortic Aneurysm
(A) Tomodensitometric and (B) echocardiographic views of an aortic root
aneurysm.
Nataf P , Lansac E Heart 2006;92:1345-1352
22. 22
Thoracic Aorta
Aortic Aneurysm
http://www.medscape.com/viewarticle/406630_15
Figure 23. Atherosclerotic vascular dis-ease in an
aortic aneurysm. Axial postcontrast image
(window = 440, level = 40) reveals a large
contrast collection projecting from the
undersurface of the aortic arch, consistent with
aneurysm (arrow). the low attention material
within the aneurysm represents thrombus
25. 25
Thoracic Aorta
Aortic Dissection
http://www.medscape.com/viewarticle/406630_15
Figure 12. Stanford type B (Debakey Type III)
aortic dissection: descending thoracic aorta.
(A) Axial postcontrast image (window = 440,
level = 40) reveals intimal flap (arrow), t = true
lumen, f = false lumen. (B) Oblique sagittal
reconstruction reveals complex nature of the
intimal flap (arrows).
26. 26
Thoracic Aorta
Epidemiology
Thoracic aneurysms
– Prevalence greater than 3-4% of those over 65
– 6 cases per 100,000 person-years
– Incidence increasing
– In the top 15 causes of death
– Thoracic aortic aneurysm – rupture 3.5/100,000 persons
Thoracic aortic dissection
– 2000 new cases/year
– Acute - 3.5/100,000 persons
– Male:Female ratio 2:1
27. 27
Thoracic Aorta
Etiologies
Underlying Etiologies
– Atherosclerosis
– Marfan’s
– Type IV Ehlers-Danlos
– Infection (syphillis)
– Arteritis (giant cell, Takayasu, Behcet’s)
– Trauma
Risk Factors
– Smoking
– COPD
– HTN
– Male gender
– Older age
– High BMI
– Abnormal aortic valve (e.g., bicuspid valve)
– Family history
32. 32
Thoracic Aorta
Natural History
Yearly Rupture or Dissection Rates for Thoracic Aortic Aneurysms: Simple
Prediction Based on Size
– 304 patients; 58.9% male; median age 65.8
– Aneurysm size – 43.7% were 4.0-4.9 cm
– Location – 72% ascending
– Follow up – average 43.1 months
– End points
Davies RR, et al. Ann Thorac Surg 2002;73:17
44
Death alone
15
Dissection alone
5
Rupture alone
4
Rupture and death (no dissection)
5
Dissection, death (no rupture)
2
Dissection, rupture (no death)
2
Dissection, rupture and death
No. Patients
Events
33. 33
Thoracic Aorta
Natural History
Davies RR, et al. Ann Thorac Surg 2002;73:17
Cumulative incidence of acute dissection or rupture as a function of initial aneurysm size.
35. 35
Thoracic Aorta
Natural History
Davies RR, et al. Ann Thorac Surg 2002;73:17
Average yearly rates of negative outcomes during the first 5 years after presentation
46. 46
Thoracic Aorta
Prognosis
Aneurysm
– Early post-op mortality 4-10%; lower for descending aneurysm repair; much
higher for aortic arch repair
– Stroke occurs 2-5%
– Renal failure requiring dialysis – 7%
– Spinal cord injury – 3%
Dissection
– Treated 10-yr survival rate 60%
– Type A
• 30% mortality surgical
• 60% mortality medical
– Type B
• 10% mortality medical
• 30% mortality surgical
47. 47
Thoracic Aorta
Underwriting Approach and Considerations
Obtain cardiology and/or vascular medical records
Review serial echos/scans as available
Review blood pressure control
Higher Risk
– Aneurysm >5 cm
– Poorly controlled blood pressure
– Increase in size >0.5 cm/yr
– Ongoing tobacco usage
– Associated cardiovascular disease (CAD, PVD, carotid disease)
– Non-atherosclerotic vascular disorders (Marfan’s, Ehlers-Danlos, etc)
Lower Risk
– Aneurysm <5 cm/stable/ well followed
– Aneurysm repaired/stable
48. 48
Thoracic Aorta
Summary
Thoracic aortic dilation/aneurysm fairly common with age
Risk factors are traditional cardiovascular risk factors
Most are asymptomatic
Thoracic aortic rupture rare
Thoracic dissection rare
Ascending aorta most common site of aneurysm formation
Low risk for aneurysms less than 4 cm
In the end, it’s not what you call it………it’s size that matters!
REMEMBER
49. superior vena cava (SVC, also known as the
cava or cva)
The superior vena cava (SVC, also known as the cava or cva) is a short,
but large diameter vein located in the anterior right
superior mediastinum. Its latin name is related to its large pipe
appearance in cadavers, 'cava' meaning 'hollow'.
49
Thoracic Aorta
50. The superior vena cava is very important for the function of
the cardiovascular system, since it largely contributes to the input of
blood to the right atrium. Any hypertensive process in the right half of the
heart or in the pulmonary circulation retrogradely affects both superior
and inferior venae cavae. This is important since the veins are not
adjusted to high pressures, which can result with forming an aneurysm
or even rupture of the wall of the SVC.
This article will discuss the anatomy and function of the superior vena
cava.
50
Thoracic Aorta
Key facts about the superior vena cavaTable quiz
Source Brachiocephalic vein, azygos vein
Draining area Upper half of the body (above the diaphragm)
Drains to Right atrium of heart
51. Contents
Anatomy
Function
Clinical notes
– Superior vena cava obstruction (SVCO)
– Superior vena cava syndrome (SVCS)
– Superior vena cava thrombosis
– Superior vena cava aneurysm
– Persistent left superior vena cava (PLSVC)
Sources
51
Thoracic Aorta
52. Anatomy
Left brachiocephalic vein
Vena brachiocephalica sinistra
1/3
Synonyms: Left innominate vein, Vena anonyma sinistra
Embryologically, the SVC is formed by the left and right brachiocephalic
veins (also known as the innominate veins) that also receive blood from
the upper limbs, certain parts of the head, one being the eyes, and neck.
There is no valve that divides the SVC from the right atrium, which
conducts blood from right atrial and right ventricular contractions
upwards into the internal jugular vein (seen as the jugular venous
pressure) and sternocleidomastoid muscle.
52
Thoracic Aorta
53. Positionally, the SVC begins behind the lower border of the 1st right
costal cartilage and descends vertically behind the 2nd and 3rd
intercostal spaces to drain into the right atrium at the level of the 3rd
costal cartilage. Its lower half is covered by a fibrous pericardium, which
is pierced by the SVC at the level of the 2nd costal cartilage.
53
Thoracic Aorta
Function
Superior vena cava coursing towards the right atrium of the
heart, returning deoxygenated blood from the body.
The SVC is one of the 2 large veins by which blood is returned from the body to the right side
of the heart. After circulating through the body systemically, deoxygenated blood returns to
the right atrium of the heart through either the SVC, which drains the upper body, or
the inferior vena cava (IVC) that drains everything below the diaphragm.
54. Clinical notes
Superior vena cava obstruction (SVCO)
This usually refers to a partial or complete obstruction of the SVC,
often in the context of cancer (lung cancer, metastatic cancer, or
lymphoma). Clinically this obstruction can lead to enlarged veins in
the head and neck, and cause shortness of breath, cough, chest
pain, and difficulty swallowing).
A clinical test known as Pemberton’s sign can be performed to
identify this condition. A positive Pemberton's sign is marked by
facial congestion and cyanosis (and/or respiratory distress) after 1
minute of having the patient elevate both arms until they touch the
sides of the face. This sign is indicative of superior vena
cava syndrome, commonly the result of a mass in the mediastinum.
54
Thoracic Aorta
55. Superior vena cava syndrome (SVCS)
This syndrome refers to a group of symptoms caused by the
obstruction of the SVC. More than 90% of the cases of SVC
obstruction are caused by cancer, most commonly bronchogenic
carcinoma, which includes small cell and non-small cell lung
carcinoma, Burkitt’s lymphoma, lymphoblastic lymphomas, pre-T-
cell lineage acute lymphoblastic leukemia, and other acute
leukemias.
Characteristic symptoms are edema of the arms and face,
development of swollen collateral veins on the front of the chest
wall, shortness of breath, difficulty swallowing, stridor, cough, and
neurological symptoms (reduced alertness, etc. from edema in
the brain or airway compromise). Again, Pemberton’s sign can be
used to identify an SVCO.
55
Thoracic Aorta
56. Superior vena cava thrombosis
The thrombosis often occurs from a thrombus around a long-
term central venous catheter (CVC), especially in cancer patients with
permanent indwelling CVCs. CVC-related thrombosis is as high as
30% in adults. However, patients can be treated with thrombolytics
or anticoagulants, or by removal of the catheter.
Superior vena cava aneurysm
Venous aneurysms arising from the mediastinal systemic veins are
extremely rare, with the majority being fusiform (“spindle-shaped”)
aneurysms that arise from the SVC.
Persistent left superior vena cava (PLSVC)
A PLSVC is an embryologic remnant that is the most common
variation of the thoracic venous system, resulting from a failure to
involute during embryologic development.
56
Thoracic Aorta
57. The inferior vena cava (IVC) is the largest vein
of the human body. It is located at
the posterior abdominal wall on the right side of
the aorta. The IVC’s function is to carry
the venous blood from the lower
limbs and abdominopelvic region to the heart.
The inferior vena cava anatomy is essential
due to the vein’s great drainage area, which
also makes it a hot topic for anatomy exams.
For that reason, this page will cover the IVC
anatomy in a way that’s easy to read and
understand.
57
Thoracic Aorta
60. Key facts
Table quiz
Definition and functionThe vein that collects
deoxygenated blood from the abdomen,
pelvis and lower limbs and carries it to the
right atrium of the heartSourceCommon iliac
veins (L5)TributariesInferior Phrenic,
right Suprarenal, Renal, right Testicular
(gonadal), Lumbar, common Iliac
and Hepatic veins
Mnemonic: Portal System Returns To Liver
In Humans
Clinical relationsInferior vena cava
thrombosis 60
Thoracic Aorta
61. Anatomy
Inferior vena cava
Vena cava inferior
1/4
Synonyms: IVC
The inferior vena cava arises from the confluence
of the common iliac veins at the level of L5
vertebra, just inferior to the bifurcation of the
abdominal aorta. It then ascends the posterior
abdominal wall, to the right side of the aorta and
the bodies of the L3-L5 vertebrae. After passing
through its fossa on the posterior liver surface, the
IVC enters the thorax by traversing the inferior
vena caval foramen of the diaphragm.
61
Thoracic Aorta
63. The tributaries of the IVC correspond to the branches of the abdominal
aorta. Note that some professors will want you to know at which
vertebral level the IVC gets its direct tributaries, so they are as follows:
The direct tributaries are the inferior phrenic veins (T8), right suprarenal
(L1), renal (L1), right testicular (gonadal) (L2), lumbar (L1-L5),
common iliac (L5) and hepatic (T8). If you want an easy way to
remember them just memorise the mnemonic
' Portal System Returns To Liver In Humans'.
Left gonadal and left suprarenal renal veins drain first into the left renal
vein
The veins of the stomach, spleen, pancreas, small and large
intestines first empty into the hepatic portal vein. The hepatic portal vein
carries this blood to the liver to be processed and detoxified. Then, the
blood reaches the IVC through the hepatic veins.
The inferior vena cava communicates with the superior vena
cava through the collateral vessels, which include the azygos
vein, lumbar veins, and vertebral venous plexuses.
63
Thoracic Aorta
65. Function
The IVC’s function is to convey the blood from the abdomen, pelvis,
and lower limbs to the right atrium of the heart. Additional IVC functions
are noticeable during some health disturbances, such as hepatic portal
vein obstruction or the obstruction of the IVC itself.
Specialized vessels called
the portocaval (portosystemic) anastomoses open if the hepatic portal
vein is obstructed. The intestinal blood then bypasses the liver and
empties into the IVC directly. In cases where the IVC is occluded,
the collateral vessels to the superior vena cava open.
Learn more about portocaval anastomoses with our article, then take this
specially designed quiz to consolidate everything you’ve learned about
the IVC and its tributaries.
65
Thoracic Aorta
66. Inferior vena cava thrombosis
Thrombosis of the inferior vena cava (IVCT) is a condition in which a
blood clot (thrombus) impedes the blood flow through the IVC. The
thrombus can be formed within the IVC itself, which is rare, or, more
commonly, travel from the deep veins of the legs in a condition called
deep venous thrombosis (DVT).
IVC thrombosis may be caused by all the conditions that lead to venous
stasis. These include congenital abnormalities of the IVC,
immobilization, obesity, pregnancy, sedentary lifestyle, and tumors of
surrounding organs. IVCT presents with symptoms of venous
obstruction, such as pain and swelling of lower limbs and scrotum. IVCT
is diagnosed by ultrasound, CT,and MRI.
Depending on the severity of the condition, the IVCT can be treated by
surgical removal of the thrombus, thrombolytic therapy, and
anticoagulant therapy. The treatment is necessary to prevent
disseminating of the thrombus into the pulmonary circulation (pulmonary
thromboembolism), which is an urgent medical condition.
Sources
66
Thoracic Aorta
69. Veins of the thoracic wall
The thoracic wall is drained anteriorly by the internal thoracic vein
and posteriorly by the azygos system of veins
69
70. The azygos system of veins serves as an important anastomotic
pathway capable of returning venous blood from the lower part of
the body to the heart if the inferior vena cava is blocked.
70
71. The major veins in the system are:
Azygos vein, on the right
Hemiazygos vein and the accessory hemiazygos vein, on the
left.
71
72. Azygos vein
The azygos vein arises opposite vertebra LI or LII
It is formed by the union of the right ascending lumbar vein , the
right subcostal vein and lumber azygos veins .
72
76. The azygos vein enters the thorax through the aortic hiatus of the
diaphragm, or it enters through or posterior to the right crus of the
diaphragm.
76
77. It ascends through the posterior mediastinum, usually to the right
of the thoracic duct.
77
78. At approximately vertebral level TIV, it arches anteriorly, over the
root of the right lung, to join the superior vena cava.
78
80. Tributaries of the azygos vein
Right superior intercostal vein
5th – 11th right posterior ICV
Hemiazygos vein;
Accessory hemiazygos vein
Esophageal veins
Mediastinal veins
Pericardial veins
Right bronchial veins
80
81. Hemiazygos vein
The hemiazygos vein (inferior hemiazygos vein) usually arises at
the junction between the left ascending lumbar vein and the left
subcostal vein .
81
83. The hemiazygos vein usually enters the thorax through the left crus
of the diaphragm, but may enter through the aortic hiatus.
83
84. It ascends through the posterior mediastinum, on the left side, to
approximately vertebral level TIX.
At this point, it crosses the vertebral column, posterior to the
thoracic aorta, esophagus, and thoracic duct, to enters the azygos
vein.
The hemiazygos vein receives the inferior three intercostal veins, the
inferior oesophageal veins, and several small mediastinal branches.
84
86. Accessory hemiazygos vein
The accessory hemiazygos vein descends on the left side of upper thoracic vertebrae up to the
vertebral level TVIII . At this point, it crosses the vertebral column to join the azygos vein, or
ends in the hemiazygos vein, or has a connection to both veins. Usually, it also has a connection
superiorly to the left superior intercostal vein. Vessels that drain into the accessory hemiazygos
vein include: the fourth to eighth left posterior intercostal veins
86
90. Sympathetic trunks
The sympathetic trunks (sympathetic chain, gangliated cord) are a
paired bundle of nerve fibers that run from the base of the skull to
the coccyx.
93. The sympathetic trunks are two parallel nerve cords extending on
either side of the vertebral column from the base of the skull to the
coccyx
94. The ganglia and trunks are connected to adjacent spinal nerves by
gray rami communicantes throughout the length of the sympathetic
trunk and by white rami communicantes in the thoracic and upper
lumbar parts of the trunk (T1 to L2).
95. The whiter rami are afferent fibers to the ganglion and found only
from T1 to L2 segments. These contain the preganglionic and
afferent sensory fibers.
The gray rami communicans are present in all segments. They are
efferent fibers of the sympathetic ganglia. These contain the
postganglionic fibers.
96. Parts of sympathetic chain
Cervical part
Thoracic part
lumber Part
Sacral part
108. Applied Anatomy
1- Spinal anesthesia at high level
may lead to temporary drop of
blood pressure.
2- In case of essential
hypertension, cutting of
sympathetic chain between T2 &
T5 will lead to drop of blood
pressure.
121. A- From Chest Wall
1- Superficial lymph vessels:
- From front of chest to
pectoral lymph nodes,
parasternal or lower deep
cervical lymph nodes.
- From back of chest to
subscapular nodes.
122. 2- Deep lymph vessels:
A- From anterior chest wall to
parasternal nodes.
B- Posterior part of chest wall to
intercostal lymph nodes (opposite
neck of ribs).
C- Four diaphragmatic nodes
(anterior, posterior and 2 lateral)
which drain diaphragm and liver.
123. B- from Thoracic
Contents
1- Anterior mediastinal
nodes.
2- Posterior mediastinal
nodes.
3- Nodes of lungs, bronchi
and trachea.
124. • Lymph vessels from:
-Anterior mediastinal nodes.
-Tracheal lymph nodes.
-Parasternal lymph nodes.
Will unit together to form broncho-
medistinal lymph vessels which joins
thoracic duct on left side and right
lymphatic duct in right side.