2. INTRODUCTION
Consists of liver, biliary tree, gall bladder
Liver is the largest gland in the body
Multiple functions
Disease of the liver and biliary tree influences drug
actions
Every anesthetic drugs are metabolized by the liver
So liver is very much important for anesthetists
4. LIVER
Weight about 1500 gm
Blood supply about 1500ml/min
Occupies right hypochondrium and epigastrium
It has two surfaces- diaphragmatic and visceral
Diaphragmatic divided into anterior, superior and
posterior
6. PORTA HEPATIS
Hilum of the liver
Vessels and ducts enter
and leave the porta
hepatis
Right and left branches
of hepatic artery
Right and left hepatic
duct
Portal vein, lymphatic
and nerves
7. LIVER
Gall bladder lies on the
visceral surface
Bare area is devoid of
peritonium and contact
with diaphragm and
supra renal gland
Visceral surface
related to
stomach,duodenum,
hepatic flexure and
right kidney
Liver is suspended
by hepatic vein and
inferior vena cava
8. SURFACE ANATOMY
Upper margin
xipesternal joint
Left fifth inter
costal space 7-8
cm from mid line
Right side to the
fifth rib, 7-11 ribs
mid axillary line
Lower border
lies at the level
of the right
costal margin
9. LOBES
Larger right lobe
Smaller left lobe
Line of attachment
–falciform ligament
anteriorly,
ligamentum teres,
ligamentum
venosum on the
visceral surface
Caudate lobe
Quadrate lobe
Lobes are not
arranged according
to vascular and
biliary channels
10. FUNCTIONAL DIVISION
Functional division of
liver are right and left
halves
Oblique line from
gallbladder bed and
groove for IVC
Middle hepatic vein
lies in this plane
Useful landmark for
radiological and
ultrasonographic
investigations
11. SEGMENTS
On the basis of blood
supply and biliary
drainage there are four
main hepatic segment
Left lateral and medial,
right lateral and medial.
Caudate lobe is
autonomous segment
Blood receives from
hepatic artery and
portal vein
drains into the IVC
Draining bile into
heptatic duct
12. BLOOD SUPPLY OF LIVER
From two sources –
arterial from hepatic
artery , venous from
portal vein
Hepatic artery arises from
coeliac truk
Hepatic artery may
arise from supp.
mesentric artery or on
aorta
Right hepatic artery from
supp.mesentric artery and
left hepatic artery from left
gastric artery
13. LYMPHATIC DRAINAGE
3-4 nodes lie in the porta hepatis
Receives lymp of gall bladder
Drain downwards to pyloric node and coeliac node
Bare area lymphatics communicate with extra
peritoneal lymphatic drain to the nodes of posterior
mediastinum.
14. NERVE SUPPLY
Both sympathetic and parasympathetic.
Sympathetic through coeliac ganglia
Vagal branch from hepatic branch of ant. Vagal
trunk
Reach through porta hepatis.
16. STRUCTURE
The hepatic lobule pinhead sized and hexagonal
shape.
Central vein and plates of cords of hepatocytes
separated by vascular space or sinosoids.
Corner of the lobule are the portal triad.
Small branch of hepatic artery portal vein and bile
ductule.
18. PORTAL VENOUS SYSTEM
Portal Vein is the upward continuation of superior
mesentric vein
Join with the splenic vein
Portal vein receives right and left gastric vein,
superior pancreatoduodenal vein and cystic vein 10
cm long no valves
19. FIVE SIDES OF PORTAL ANASTOMOSIS
Lower end esophagus
Upper end of anal canal
Bare area of liver
Periumblical region
Retroperitoneal area
In portal hypertension 80% of portal blood may be
Shunted, 20% reaches to the liver.