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HEPATOBILIARY SYSTEM
INTRODUCTION
 Consists of liver, biliary tree, gall bladder
 Liver is the largest gland in the body
 Multiple functions
 Disease of the liver and biliary tree influences drug
actions
 Every anesthetic drugs are metabolized by the liver
 So liver is very much important for anesthetists
LIVER
LIVER
 Weight about 1500 gm
 Blood supply about 1500ml/min
 Occupies right hypochondrium and epigastrium
 It has two surfaces- diaphragmatic and visceral
 Diaphragmatic divided into anterior, superior and
posterior
LIVER
PORTA HEPATIS
 Hilum of the liver
 Vessels and ducts enter
and leave the porta
hepatis
 Right and left branches
of hepatic artery
 Right and left hepatic
duct
 Portal vein, lymphatic
and nerves
LIVER
 Gall bladder lies on the
visceral surface
 Bare area is devoid of
peritonium and contact
with diaphragm and
supra renal gland
 Visceral surface
related to
stomach,duodenum,
hepatic flexure and
right kidney
 Liver is suspended
by hepatic vein and
inferior vena cava
SURFACE ANATOMY
 Upper margin
xipesternal joint
 Left fifth inter
costal space 7-8
cm from mid line
 Right side to the
fifth rib, 7-11 ribs
mid axillary line
 Lower border
lies at the level
of the right
costal margin
LOBES
 Larger right lobe
 Smaller left lobe
 Line of attachment
–falciform ligament
anteriorly,
ligamentum teres,
ligamentum
venosum on the
visceral surface
 Caudate lobe
 Quadrate lobe
 Lobes are not
arranged according
to vascular and
biliary channels
FUNCTIONAL DIVISION
 Functional division of
liver are right and left
halves
 Oblique line from
gallbladder bed and
groove for IVC
 Middle hepatic vein
lies in this plane
 Useful landmark for
radiological and
ultrasonographic
investigations
SEGMENTS
 On the basis of blood
supply and biliary
drainage there are four
main hepatic segment
 Left lateral and medial,
right lateral and medial.
 Caudate lobe is
autonomous segment
 Blood receives from
hepatic artery and
portal vein
drains into the IVC
 Draining bile into
heptatic duct
BLOOD SUPPLY OF LIVER
 From two sources –
arterial from hepatic
artery , venous from
portal vein
 Hepatic artery arises from
coeliac truk
 Hepatic artery may
arise from supp.
mesentric artery or on
aorta
 Right hepatic artery from
supp.mesentric artery and
left hepatic artery from left
gastric artery
LYMPHATIC DRAINAGE
 3-4 nodes lie in the porta hepatis
 Receives lymp of gall bladder
 Drain downwards to pyloric node and coeliac node
 Bare area lymphatics communicate with extra
peritoneal lymphatic drain to the nodes of posterior
mediastinum.
NERVE SUPPLY
 Both sympathetic and parasympathetic.
 Sympathetic through coeliac ganglia
 Vagal branch from hepatic branch of ant. Vagal
trunk
 Reach through porta hepatis.
STRUCTURE OF LIVER
STRUCTURE
 The hepatic lobule pinhead sized and hexagonal
shape.
 Central vein and plates of cords of hepatocytes
separated by vascular space or sinosoids.
 Corner of the lobule are the portal triad.
 Small branch of hepatic artery portal vein and bile
ductule.
PORTAL SYSTEM
PORTAL VENOUS SYSTEM
 Portal Vein is the upward continuation of superior
mesentric vein
 Join with the splenic vein
 Portal vein receives right and left gastric vein,
superior pancreatoduodenal vein and cystic vein 10
cm long no valves
FIVE SIDES OF PORTAL ANASTOMOSIS
 Lower end esophagus
 Upper end of anal canal
 Bare area of liver
 Periumblical region
 Retroperitoneal area
In portal hypertension 80% of portal blood may be
Shunted, 20% reaches to the liver.
THANK YOU

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hepatobiliary system 2024.pptx hepatobiliary system

  • 2. INTRODUCTION  Consists of liver, biliary tree, gall bladder  Liver is the largest gland in the body  Multiple functions  Disease of the liver and biliary tree influences drug actions  Every anesthetic drugs are metabolized by the liver  So liver is very much important for anesthetists
  • 4. LIVER  Weight about 1500 gm  Blood supply about 1500ml/min  Occupies right hypochondrium and epigastrium  It has two surfaces- diaphragmatic and visceral  Diaphragmatic divided into anterior, superior and posterior
  • 6. PORTA HEPATIS  Hilum of the liver  Vessels and ducts enter and leave the porta hepatis  Right and left branches of hepatic artery  Right and left hepatic duct  Portal vein, lymphatic and nerves
  • 7. LIVER  Gall bladder lies on the visceral surface  Bare area is devoid of peritonium and contact with diaphragm and supra renal gland  Visceral surface related to stomach,duodenum, hepatic flexure and right kidney  Liver is suspended by hepatic vein and inferior vena cava
  • 8. SURFACE ANATOMY  Upper margin xipesternal joint  Left fifth inter costal space 7-8 cm from mid line  Right side to the fifth rib, 7-11 ribs mid axillary line  Lower border lies at the level of the right costal margin
  • 9. LOBES  Larger right lobe  Smaller left lobe  Line of attachment –falciform ligament anteriorly, ligamentum teres, ligamentum venosum on the visceral surface  Caudate lobe  Quadrate lobe  Lobes are not arranged according to vascular and biliary channels
  • 10. FUNCTIONAL DIVISION  Functional division of liver are right and left halves  Oblique line from gallbladder bed and groove for IVC  Middle hepatic vein lies in this plane  Useful landmark for radiological and ultrasonographic investigations
  • 11. SEGMENTS  On the basis of blood supply and biliary drainage there are four main hepatic segment  Left lateral and medial, right lateral and medial.  Caudate lobe is autonomous segment  Blood receives from hepatic artery and portal vein drains into the IVC  Draining bile into heptatic duct
  • 12. BLOOD SUPPLY OF LIVER  From two sources – arterial from hepatic artery , venous from portal vein  Hepatic artery arises from coeliac truk  Hepatic artery may arise from supp. mesentric artery or on aorta  Right hepatic artery from supp.mesentric artery and left hepatic artery from left gastric artery
  • 13. LYMPHATIC DRAINAGE  3-4 nodes lie in the porta hepatis  Receives lymp of gall bladder  Drain downwards to pyloric node and coeliac node  Bare area lymphatics communicate with extra peritoneal lymphatic drain to the nodes of posterior mediastinum.
  • 14. NERVE SUPPLY  Both sympathetic and parasympathetic.  Sympathetic through coeliac ganglia  Vagal branch from hepatic branch of ant. Vagal trunk  Reach through porta hepatis.
  • 16. STRUCTURE  The hepatic lobule pinhead sized and hexagonal shape.  Central vein and plates of cords of hepatocytes separated by vascular space or sinosoids.  Corner of the lobule are the portal triad.  Small branch of hepatic artery portal vein and bile ductule.
  • 18. PORTAL VENOUS SYSTEM  Portal Vein is the upward continuation of superior mesentric vein  Join with the splenic vein  Portal vein receives right and left gastric vein, superior pancreatoduodenal vein and cystic vein 10 cm long no valves
  • 19. FIVE SIDES OF PORTAL ANASTOMOSIS  Lower end esophagus  Upper end of anal canal  Bare area of liver  Periumblical region  Retroperitoneal area In portal hypertension 80% of portal blood may be Shunted, 20% reaches to the liver.