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EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
Human Circulatory System
The human body is a complex machine, requiring many processes to function efficiently. To keep these
crucial processes running without any hitches, vital elements and components need to be delivered to the
various parts of the body. This role of transportation is undertaken by the human circulatory system, moving
essential nutrients and minerals throughout the body and metabolic waste products away from the body.
Human Circulatory System
The human circulatory system consists of a network of arteries, veins, and capillaries, with the heart
pumping blood through it. Its primary role is to provide essential nutrients, minerals, and hormones to various
parts of the body.
Alternatively, the circulatory system is also responsible for collecting metabolic waste and toxins from
the cells and tissues to be purified or expelled from the body.
Organs of Circulatory System
The human circulatory system comprises 2 main systems;
(1) Blood circulatory system
(2) Lymphatic system
Blood circulatory System is made up of three main organs that have specific roles and functions. The vital
circulatory system organs include:
I. Heart II. Blood III. Blood Vessels
Heart Size - 5 × 3.5 inches Colour – Pink Shape – Conical Weight - 300 gm.
Position-It is situated in the thoracic cavity, between the lungs.
• Its triangular, superior-broad portion is tilted slightly towards the right side, its lower narrow portion is
tilted towards the left side.
• Heart is enclosed from all the sides by an envelope of two membranes called pericardial membranes.
• The narrow space in between these two membranes is called the pericardial cavity. Fluid is present in
this cavity, called pericardial fluid.
 Pericardial fluid prevents the heart from external jerks.
 It reduces the friction during contraction.
 The human heart is divisible into four chambers.
 The upper two chambers are atriums (atria) while the lower two chambers are called ventricles.
The External Structure of Heart
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
• Parts of Lower chamber of the heart is smaller and its walls are thin.
• Parts of Lower chamber is broad and muscular.
• Ventricles have a thicker wall than atriums. Internal Structure of Human Heart
• Partition between right and left chambers of heart is known as septum.
a. Right Atrium
• The right atrium has the openings of the superior vena cava, inferior vena cava.
• Deoxygenated blood from the veins of the head, neck and upper limbs enters the right atrium by superior
vena cava and from the rest of the body and lower limbs by the inferior vena cava.
• The coronary sinus, which drains deoxygenated blood from the heart muscle.
• From the right atrium blood passes into the right ventricle through a tricuspid valve.
b. Right Ventricle
• Blood leaves the right ventricle through the pulmonary artery. It is guarded by a semilunar valve.
• This artery further divides into right and left pulmonary arteries entering into the two lungs where they
further branch into pulmonary capillaries in alveoli.
c. Left Atrium (Atrium)
• This chamber receives pulmonary veins from each lung from where they bring oxygenated blood.
• The left atrium empties its blood into the left ventricle through a mitral or bicuspid valve.
d. Left Ventricle:
• Blood leaves the left ventricle by the large, main artery of the body called the aorta.
• The opening from the left ventricle into the aorta is guarded by the aortic semilunar valve.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
The Internal Structure of the Heart
Working of the heart
• The heart of the human works like a pump.
• Pure oxygenated blood enters the left atrium from lungs through pulmonary veins.
• The deoxygenated blood from various parts of the body enters the right atrium through veins and
capillaries.
• The two atriums contract simultaneously so the oxygenated blood from the left atrium to the left ventricle
and deoxygenated blood from the right atrium is pumped into the right ventricle.
• Now both the ventricles contract simultaneously so the pressure is created on the blood and the valves
between atrium and ventricle close and the blood do not go back into the atrium.
• Due to this pressure, the aorta valve opens and the blood comes into the aorta, from here, blood is sent to
different parts of the body with the help of various arteries.
• By the contraction of the right ventricle, blood reaches the lungs through pulmonary arteries where it gets
reoxygenated.
Heartbeat
• Rhythmic contraction and expansion of the heart is called heartbeat. Contraction and expansion occur
separately in the atria and ventricles.
• In some heart patients, the heart does not beat normally. The muscle cells stop functioning. In such
patients, a machine called a pacemaker is inserted in the patient's heart, so that heart beats normally.
 Heartbeat in humans is 72 times in one minute.
• Each heartbeat has two components, systole, and diastole. Systole represents contraction while diastole
represents expansion or distension of heart chambers.
• Systolic pressure: -When ventricles contract and pushes the blood in artery under high pressure is called
systolic pressure. Normal systolic pressure is 120 mm Hg at 1 atmospheric pressure.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
Diastolic pressure: - When ventricles expansion and pushes the blood in artery under low pressure is
called diastolic pressure. Normal systolic pressure is 80 mm Hg at 1 atmospheric pressure.
 Blood pressure is measured by Sphygmomanometer.
Cardiac Cycle: The sequence of events that takes place during the completion of one heartbeat.
Pulse: A wave of distension passes along the arteries following each ventricular systole. This wave of
distension is called an arterial pulse.
• It is generally felt by placing fingers over the radial artery at the wrist.
• The pulse rate is the same as the heartbeat rate.
Electrocardiogram (ECG) The functioning of the heart can be graphically recorded by an instrument called an
electrocardiograph.
Functions of Circulatory System
The most important function of the blood circulatory system is transporting oxygen throughout the body.
The other vital functions of the human circulatory system are as follows:
(1) It helps in sustaining all the organ systems.
(2) It transports blood, nutrients, oxygen, carbon dioxide, and hormones throughout the body.
(3) It protects cells from pathogens.
(4) It acts as an interface for cell-to-cell interaction.
(5) The substances present in the blood help repair the damaged tissue.
Types of Circulatory systems
There are two types of circulatory system found in animals: -
(i) Open Circulatory System: In this type of circulatory system, the main blood vessels arise from
the heart and pour the blood into tissue spaces (sinuses). e.g. Arthropoda (Cockroach),
Echinodermata.
(ii) Closed Circulatory System: In this type of circulatory system, the blood remains only in the
blood vessels and is carried to the various organ through vessels and capillaries. e.g. Human
beings, Annelida (Earthworm), some molluscs.
• In human beings, the circulatory (transport) system is divided into two systems:
(i) Blood Circulatory System
i. Blood
ii. Blood vessels
iii. Heart
(ii) Lymphatic System
i. Lymph
ii. Lymph vessels
iii. Lymph vessels
Blood
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
 Blood is an important fluid conducting tissue, which transports the materials to different body parts.
Composition of Blood Liquid part - (Matrix) - Blood plasma
Solid part - Blood corpuscles - (RBC, WBC and Platelets)
Plasma It composes 55% of blood.
• The plasma has 90-92% water and the remaining 8% -10% are other materials.
• The plasma is a faint yellow viscous fluid.  Plasma contains some soluble proteins (serum albumin,
serum globulins, prothrombin, and fibrinogen), inorganic salts, food materials, waste products, dissolved
gases, anticoagulants, and antibodies.
Functions of Plasma
• Transportation of nutrients, respiratory gases, excretion of wastes and hormones of endoc rine glands.
• Prothrombin and fibrinogen plasma proteins help in blood clotting at injuries.
• Globulins of blood plasma act as antibodies and provide immunity (disease resistance) to the body.
• Plasma also helps in the transportation of minerals like iron, copper etc.
Blood Corpuscles
• They form 45% part of blood.
• Erythrocytes or Red Blood Corpuscles (RBC)
• Leucocytes or White Blood Corpuscles (WBC)
• Platelets or Thrombocytes.
Functions of Blood
(1) Transportation of oxygen from lungs to tissues.
(2) Transportation of carbon dioxide from the tissues to the lungs.
(3) Transportation of excretory material from the tissues to the kidneys.
(4) Transportation of digested food from the small intestine to the tissue.
(5) Distribution of hormones and enzymes.
(6) Formation of clots to prevent blood loss.
(7) Distribution of heat and temperature control:
(8) Prevention of infection and wound healing: WBCs in the blood help in wound healing. Bacteria are
destroyed by the WBCs before they can enter the general circulation. Also, the WBCs provide a defense
to the body against disease germs and foreign substances.
Blood vessels In humans, three types of blood vessels are present.
1) Arteries: The vessels which carry blood from the heart to various organs of the body.
2) Veins: They collect the blood from different parts of the body and pour it into the heart.
3) Capillaries: These are the smallest blood vessels and one-cell thick.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
The major differences between various blood vessels have been given in Table.
Comparative Study of Blood Vessels
Features Artery Vein Capillaries
1 Direction
of blood
flow
Take the blood away
from heart to different
parts of body.
Bring the blood towards
the heart from various
body parts
Blood flows from arterioles
(capillaries) to venules.
2 Kind of
blood
Oxygenated blood except
in pulmonary artery.
Deoxygenated blood
except in pulmonary vein.
Blood changes from oxygenated
to deoxygenated.
3 Blood
pressure
Pressure is high Pressure is low Pressure is extremely low
4 Blood flow Blood flows rapidly with
jerks
Blood flows smoothly
without jerks
.. Blood flows smoothly without
jerks
5 Lumen Narrow Wide Very small
6 valves Absent Present Absent
7 Location Mostly deep seated . Mostly superficial Form a network all over the
body and in the organs.
Lymphatic System
• The human circulatory system consists of another body fluid called lymph. It is also known as tissue
fluid.
• It is produced by the lymphatic system which comprises a network of interconnected organs, nodes, and
ducts.
• Lymph is a colorless fluid consisting of salts, proteins, water, which transport and circulates digested
food and absorbed fat to intercellular spaces in the tissues.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
• Unlike the circulatory system, lymph is not pumped; instead, it passively flows through a network of
vessels.
Excretion in Human Beings & Plants
EXCRETION :
The biological process of removal of harmful nitrogenous wastes from the body is called excretion. The waste
products in animals include:
(i) Nitrogenous compounds like ammonia, urea and uric acid.
(ii) Carbon dioxide and water.
(iii) Excess salts and vitamins.
(iv) Unwanted medicines.
Ammonotelic organisms are those which excrete ammonia. e.g. most aquatic animals.
Ureotelic organisms are those which excrete urea. e.g. sharks, frogs, mammals.
Uricotelic organisms are those which excrete uric acid. e.g. birds, insects, land snails, many reptiles.
Excretory Organs/Structures in Animals: -
Animals Amoeba Hydra Flatworm Earthworm Insects e.g. cockroach All chord ates
Excretory
Structures
Cellular
surface
Body
surface
Protonephridia
(flame cells)
Nephridia Malpighi an tubules Kidneys
Waste
products
CO2 and
ammonia
CO2 and
ammonia
Mainly
ammonia
ammonia and
urea Uric acid
Uric Acid Urea
HUMAN EXCRETORY SYSTEM: Human excretory system consists of: -
– A pair of kidneys – A pair of ureters. – Urinary bladder. – Urethra
KIDNEY :
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
• The main excretory organ of our body are kidneys.
 HUMAN EXCRETORY SYSTEM
> The excretory system collects the liquid wastes of the body and removes them.
> The excretory system of human consists:
o Two kidneys
o Two ureters
o Bladders
o Urethra
o Bean shaped organs towards back of our body just above the waist.
o Every person has two kidneys.
Colour – Dark red
Shape – Bean shaped
Weight – 125–170 gms. Size – 10 cm length, 5 cm breadth, 3 cm thickness.
Position – Located lateraly either sides of vertebral column.
External Structure: -
• Each kidney is surrounded and covered by a tough, fibrous, capsule of connective tissues. This capsule
is called renal capsule.
• Lateral surfaces of kidney are convex while medial surfaces are concave.
• Each kidney is made up of a large number (10 lakhs) of excretory units called Nephrons.
• The human kidney is not located at similar positions due to presence of liver above right kidney,
so the right kidney get slightly lower position.
Internal Structure:
• The internal structure of kidneys can be divided into two parts.
• Its outer part is called cortex and inner part is called medulla.
• Nephron is the structural and functional unit of excretion.
• A nephron consists of a long coiled tubule differentiated into proximal nephron, loop of Henle and
distal nephron. The latter opens into the collecting tubule.
• At the proximal end of the nephron, a double walled cup-shaped structure is present called Bowman's
capsule.
• It consists of network of capillaries called glomerulus.
• One end of the glomerulus is attached to renal artery and the other end to the renal vein.
• In the glomerulus, blood comes in through afferent arteriole and blood is drained out through efferent
arteriole.
• Glomerulus and Bowman capsule are collectively called Malpighian body or renal corpuscle.
• Structure of Nephron: -
• Nephron is the structural and functional unit of kidney, which is about 3 cm long and 20-60 μm in
diameter.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
• Each kidney has about one million nephrons in humans. A nephron can be divided into three regions:
• The function of glomerulus is to filter the blood passing through it. This process is called ultrafiltration.
(I) Proximal nephron (Bowman's capsule + Proximal convoluted tubule)
(II) Loop of Henle (Ascending + Descending limb)
(III) Distal nephron (Distal convoluted tubule which opens into collecting duct)
(I) Proximal nephron: Nephron tubule is closed at its proximal (starting) end but its distal end is open
and continues into the loop of Henle. At the proximal or closed end the nephron is expanded and
curved inwardly to form a double-walled cup shaped Bowman's capsule. Within the Bowman's
capsule a network or tuft of capillaries is present, it is called glomerulus. Diameter of afferent
arteriole is greater than efferent arteriole.
(II) Loop of Henle: It starts after the proximal convoluted tubule, It ends before the distal convoluted
tubule. This hairpin like loop has a descending limb, followed by an ascending limb.
(III) Distal nephron: The ascending limb of Henle's loop merges into distal convoluted tubule. The
distal convoluted tubules of a number of adjacent nephrons open into a common collecting duct or
tubule.
Ureter:
• The collecting ducts open into the ureter.
• Each ureter originates from interior part of kidney.
• The anterior part of the ureter is broad, like a funnel and called pelvis and its posterior part is in the form
of long tubule.
Urinary Bladder:
• Each ureter opens into the urinary bladder.
• The structure of urinary bladder is muscular sac like and pear shaped.
• Its wall is flexible, it collects urine when necessary by the contraction of muscles, the urine is excreted
through urethra.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
Urethra: It is a muscular and tubular structure, which extends from the urinary bladder to the outside. It
carries the urine to the outside.
Micturition: Micturition is the term used for urination. (Passing out of urine)
Functions of Kidney:
> Regulation of water and electrolyte balance. (Osmoregulation)
> Regulation of acid base balance.
> Regulation of blood pressure.
> Excretion of metabolic waste and foreign chemicals.
Physiology of Excretion: -
> The impure blood enters to each kidney through renal artery.
> The afferent arterioles which is branch of renal artery provides blood to the glomerulus.
> Glomerulus is a group of blood capillaries formed by division of afferent arterioles located in Bowman
capsule.
> The arterioles which carry blood away from glomerulus are called efferent arterioles.
> The radius of afferent arterioles is greater than that of efferent arterioles so the pressure in glomerulus
increases which is necessary for ultrafiltration.
> Due to the blood pressure, water, glucose, urea, uric acid and some salt from the blood of afferent
arteriole filter in Bowman capsule through ultra-filtration.
> It also contains glucose, amino acid and some useful salts along with filtrate.
> This liquid from the Bowman capsule moves through the glandular part of the nephron.
> From glucose, useful salt and some part of water is reabsorbed. The amount of water reabsorbed
depends on how much excess water there is in the body and on how much of dissolved waste there is to
be excreted.
> The remaining liquid now contain only waste material is called urine.
> The urine from the nephron is collected in urinary bladder through ureter.
> Urine is stored in the urinary bladder until the pressure of the expanded bladder leads to the urge to pass
it out through the urethra.
> By the contraction of muscles of urinary bladder, the urine passes out of the body when necessary.
> All the systems of our body keep the internal environment stable even on the changing conditions of
external environment.
> Usually the homeostatic activities are performed by excretory organ.
> They not only excrete out salts and nitrogenous waste products but also perform important role of water
balance.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
Osmoregulation: - The process of maintaining the right amount of water and proper ionic balance in the body
is called osmoregulation.
Urine Formation: - It involves three processes: glomerular filtration (ultrafiltration), tubular reabsorption and
tubular secretion.
(1) Ultrafiltration: -
> Walls of glomerulus and Bowman's capsule are thin and semipermeable membrane. In the glomerulus
there are many minute pores present.
> Afferent arteriole is wider and releases the blood into glomerulus, whereas efferent arteriole is narrow.
Thus, there is development of high blood pressure.
> Due to this pressure, separation of small, selective molecules ions from the large molecules in the blood
occurs and called ultrafiltration.
> Fluid which is filtered out from the blood is called as glomerulus filterate / capsular filtrate / ultrafiltration.
(2) Tubular Reabsorption: -
> The ultrafiltration contains salts, glucose, amino acids, urea, uric acid and large amount of water.
> Glucose, salts, amino acids and water are reabsorbed by various parts of nephron and finally they enter
into the surroundings blood capillaries.
(3) Tubular secretion: -
It is removal of wastes from the surrounding blood capillaries into the glomerular filtrate.
Glomerular filtrate entering collecting duct is called urine. Urine composition is different from filtrate by the
loss as well as gain of many substances during the course of nephrons.
Chemical composition of urine:
> Urine is slightly acidic liquid, light yellow in colour.
> The healthy human being has 95% water, 5% urea, uric acid and salts of phosphoric acid.
> A young and healthy person excretes 1.5-1.8 liters’ urine per day.
> This quantity may increase due to intake of tea, coffee, wine etc.
 Role of lungs in excretion: Human lungs eliminate around 18L of CO2 per hour and about 400ml of
water per day in normal resting condition. Water loss via the lungs is small in hot humid climate and
large in cold dry climates.
 Role of skin in excretion: - Human possess two types of glands on skin;
(1) Sweat glands: - These excrete sweat, contain 99.5% Water, NaCl, Lactic acid, Urea, Amino acid and
glucose.
(2) Sebaceous glands: - These secrete sebum which contain waxes, sterols, hydrocarbons and fatty acids.
 Role of liver in excretion: -
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
> Liver is the main site for elimination of cholesterol, bile pigments, inactivated products of steroid
hormones, some vitamins and many drugs. Bile carries these materials to the intestine from where they
are excreted with the faeces.
 ARTIFICIAL KIDNEY OR HAEMODIALYSIS
> Kidney dialysis also known as hemodialysis or renal dialysis, is a medical treatment used to remove
nitrogenous waste materials from the blood of patients lacking kidney function or kidney failure, due
to infections, injury or restricted blood flow to kidneys.
> In this procedure, the blood is circulated through a machine known as artificial kidney or dialyser that
removes wastes and excess fluid from the bloodstream.
> The blood from an artery is pumped through a dialyser or artificial kidney, where it flows through a
semipermeable membrane which removes unwanted elements in the blood by diffusion.
> The blood is then returned to the body through a vein.
> Main difference of kidney & dialysis is that there is no reabsorption in dialysis.
> In kidney, initial filtrate is about 180L daily but actual excretion is only a liter or two a day.
Excretion
• All the living organisms perform various biochemical reactions and produce toxic .
• If these toxic substances accumulate in body harms an organism, so for normal working an organism,
removal of these toxic substances from the body is necessary.
• The process of removal of toxic wastes from the body of an organism is called excretion.
> Excretion in Plants.
• Plants produce a number of waste products during their life processes.
• The plants remove their waste products by different methods.
> Gaseous excretion: -
• The main products produced by plants are carbon dioxide, water and oxygen.
• Carbon dioxide and water vapour are produced during respiration by plants whereas oxygen is produced
as a waste during photosynthesis.
• The gaseous wastes of respiration and photosynthesis in plants carbon dioxide, oxygen and water vapour
are removed through stomata in leaves and lenticels in stems and released in air.
• The plants excrete carbon dioxide produced as a waste during respiration only at night time.
• As during the day time carbon dioxide released during respiration is being used during the process of
photosynthesis.
• The excrete oxygen and water vapour as waste during day time.
• The removal of Water vapour during day through stomata is called transpiration.
EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE
> Other wastes: -
• The plants also store some of the waste from their body parts like leaves, fruits and bark of trees.
• The remove these wastes by shedding of leaves, felling of fruits and peeling of bark.
• When the dead leaves bark and ripe fruits fall off from trees, then the waste products contained in them
are also removed.
• The plants also secrete their wastes in the form of gum and resins from their stems and branches
• The plants also excrete some waste substances into the soil and around them.
Summary
• The plants get rid of gaseous waste products through stomata in leaves and lenticels in stem.
• The get rid of stored solid and liquid wastes by the shedding of leaves, peeling of bark and felling of
fruits.
• The get rid of wastes by secreting them in the form of gum and resins.
• Plants also excrete some waste substances into soil around them.
Excretion in Animals.
• Different animals have different arrangements (organs) for excretion of waste.
• In Amoeba and other single cellular organisms
o In Amoeba and other single cellular organisms remove carbon dioxide by diffusion through the cell
membrane.
o Nitrogenous wastes and excess water are removed by the contractile movement of vacuole.
• In earthworm,
> The tubular structures called nephridia are the excretory organs.
> The moist skin also acts as an excretory organ.
• In human and other mammals
> The microscopic thin tubules form nephron, which works as excretory unit and remove nitrogenous
substances.
> Carbon dioxide produced during respiration is removed.
> Skin also removes salt and water by sweating.
 Removal of waste products in Human.
> The major wastes produced by human body are carbon dioxide and Urea.
> Carbon dioxide is produced as a waste by the oxidation of food during respiration.
> Human lungs excrete carbon dioxide.
> Kidneys excrete urea.

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CIRCULATORY SYSTEM

  • 1. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE Human Circulatory System The human body is a complex machine, requiring many processes to function efficiently. To keep these crucial processes running without any hitches, vital elements and components need to be delivered to the various parts of the body. This role of transportation is undertaken by the human circulatory system, moving essential nutrients and minerals throughout the body and metabolic waste products away from the body. Human Circulatory System The human circulatory system consists of a network of arteries, veins, and capillaries, with the heart pumping blood through it. Its primary role is to provide essential nutrients, minerals, and hormones to various parts of the body. Alternatively, the circulatory system is also responsible for collecting metabolic waste and toxins from the cells and tissues to be purified or expelled from the body. Organs of Circulatory System The human circulatory system comprises 2 main systems; (1) Blood circulatory system (2) Lymphatic system Blood circulatory System is made up of three main organs that have specific roles and functions. The vital circulatory system organs include: I. Heart II. Blood III. Blood Vessels Heart Size - 5 × 3.5 inches Colour – Pink Shape – Conical Weight - 300 gm. Position-It is situated in the thoracic cavity, between the lungs. • Its triangular, superior-broad portion is tilted slightly towards the right side, its lower narrow portion is tilted towards the left side. • Heart is enclosed from all the sides by an envelope of two membranes called pericardial membranes. • The narrow space in between these two membranes is called the pericardial cavity. Fluid is present in this cavity, called pericardial fluid.  Pericardial fluid prevents the heart from external jerks.  It reduces the friction during contraction.  The human heart is divisible into four chambers.  The upper two chambers are atriums (atria) while the lower two chambers are called ventricles. The External Structure of Heart
  • 2. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE • Parts of Lower chamber of the heart is smaller and its walls are thin. • Parts of Lower chamber is broad and muscular. • Ventricles have a thicker wall than atriums. Internal Structure of Human Heart • Partition between right and left chambers of heart is known as septum. a. Right Atrium • The right atrium has the openings of the superior vena cava, inferior vena cava. • Deoxygenated blood from the veins of the head, neck and upper limbs enters the right atrium by superior vena cava and from the rest of the body and lower limbs by the inferior vena cava. • The coronary sinus, which drains deoxygenated blood from the heart muscle. • From the right atrium blood passes into the right ventricle through a tricuspid valve. b. Right Ventricle • Blood leaves the right ventricle through the pulmonary artery. It is guarded by a semilunar valve. • This artery further divides into right and left pulmonary arteries entering into the two lungs where they further branch into pulmonary capillaries in alveoli. c. Left Atrium (Atrium) • This chamber receives pulmonary veins from each lung from where they bring oxygenated blood. • The left atrium empties its blood into the left ventricle through a mitral or bicuspid valve. d. Left Ventricle: • Blood leaves the left ventricle by the large, main artery of the body called the aorta. • The opening from the left ventricle into the aorta is guarded by the aortic semilunar valve.
  • 3. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE The Internal Structure of the Heart Working of the heart • The heart of the human works like a pump. • Pure oxygenated blood enters the left atrium from lungs through pulmonary veins. • The deoxygenated blood from various parts of the body enters the right atrium through veins and capillaries. • The two atriums contract simultaneously so the oxygenated blood from the left atrium to the left ventricle and deoxygenated blood from the right atrium is pumped into the right ventricle. • Now both the ventricles contract simultaneously so the pressure is created on the blood and the valves between atrium and ventricle close and the blood do not go back into the atrium. • Due to this pressure, the aorta valve opens and the blood comes into the aorta, from here, blood is sent to different parts of the body with the help of various arteries. • By the contraction of the right ventricle, blood reaches the lungs through pulmonary arteries where it gets reoxygenated. Heartbeat • Rhythmic contraction and expansion of the heart is called heartbeat. Contraction and expansion occur separately in the atria and ventricles. • In some heart patients, the heart does not beat normally. The muscle cells stop functioning. In such patients, a machine called a pacemaker is inserted in the patient's heart, so that heart beats normally.  Heartbeat in humans is 72 times in one minute. • Each heartbeat has two components, systole, and diastole. Systole represents contraction while diastole represents expansion or distension of heart chambers. • Systolic pressure: -When ventricles contract and pushes the blood in artery under high pressure is called systolic pressure. Normal systolic pressure is 120 mm Hg at 1 atmospheric pressure.
  • 4. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE Diastolic pressure: - When ventricles expansion and pushes the blood in artery under low pressure is called diastolic pressure. Normal systolic pressure is 80 mm Hg at 1 atmospheric pressure.  Blood pressure is measured by Sphygmomanometer. Cardiac Cycle: The sequence of events that takes place during the completion of one heartbeat. Pulse: A wave of distension passes along the arteries following each ventricular systole. This wave of distension is called an arterial pulse. • It is generally felt by placing fingers over the radial artery at the wrist. • The pulse rate is the same as the heartbeat rate. Electrocardiogram (ECG) The functioning of the heart can be graphically recorded by an instrument called an electrocardiograph. Functions of Circulatory System The most important function of the blood circulatory system is transporting oxygen throughout the body. The other vital functions of the human circulatory system are as follows: (1) It helps in sustaining all the organ systems. (2) It transports blood, nutrients, oxygen, carbon dioxide, and hormones throughout the body. (3) It protects cells from pathogens. (4) It acts as an interface for cell-to-cell interaction. (5) The substances present in the blood help repair the damaged tissue. Types of Circulatory systems There are two types of circulatory system found in animals: - (i) Open Circulatory System: In this type of circulatory system, the main blood vessels arise from the heart and pour the blood into tissue spaces (sinuses). e.g. Arthropoda (Cockroach), Echinodermata. (ii) Closed Circulatory System: In this type of circulatory system, the blood remains only in the blood vessels and is carried to the various organ through vessels and capillaries. e.g. Human beings, Annelida (Earthworm), some molluscs. • In human beings, the circulatory (transport) system is divided into two systems: (i) Blood Circulatory System i. Blood ii. Blood vessels iii. Heart (ii) Lymphatic System i. Lymph ii. Lymph vessels iii. Lymph vessels Blood
  • 5. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE  Blood is an important fluid conducting tissue, which transports the materials to different body parts. Composition of Blood Liquid part - (Matrix) - Blood plasma Solid part - Blood corpuscles - (RBC, WBC and Platelets) Plasma It composes 55% of blood. • The plasma has 90-92% water and the remaining 8% -10% are other materials. • The plasma is a faint yellow viscous fluid.  Plasma contains some soluble proteins (serum albumin, serum globulins, prothrombin, and fibrinogen), inorganic salts, food materials, waste products, dissolved gases, anticoagulants, and antibodies. Functions of Plasma • Transportation of nutrients, respiratory gases, excretion of wastes and hormones of endoc rine glands. • Prothrombin and fibrinogen plasma proteins help in blood clotting at injuries. • Globulins of blood plasma act as antibodies and provide immunity (disease resistance) to the body. • Plasma also helps in the transportation of minerals like iron, copper etc. Blood Corpuscles • They form 45% part of blood. • Erythrocytes or Red Blood Corpuscles (RBC) • Leucocytes or White Blood Corpuscles (WBC) • Platelets or Thrombocytes. Functions of Blood (1) Transportation of oxygen from lungs to tissues. (2) Transportation of carbon dioxide from the tissues to the lungs. (3) Transportation of excretory material from the tissues to the kidneys. (4) Transportation of digested food from the small intestine to the tissue. (5) Distribution of hormones and enzymes. (6) Formation of clots to prevent blood loss. (7) Distribution of heat and temperature control: (8) Prevention of infection and wound healing: WBCs in the blood help in wound healing. Bacteria are destroyed by the WBCs before they can enter the general circulation. Also, the WBCs provide a defense to the body against disease germs and foreign substances. Blood vessels In humans, three types of blood vessels are present. 1) Arteries: The vessels which carry blood from the heart to various organs of the body. 2) Veins: They collect the blood from different parts of the body and pour it into the heart. 3) Capillaries: These are the smallest blood vessels and one-cell thick.
  • 6. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE The major differences between various blood vessels have been given in Table. Comparative Study of Blood Vessels Features Artery Vein Capillaries 1 Direction of blood flow Take the blood away from heart to different parts of body. Bring the blood towards the heart from various body parts Blood flows from arterioles (capillaries) to venules. 2 Kind of blood Oxygenated blood except in pulmonary artery. Deoxygenated blood except in pulmonary vein. Blood changes from oxygenated to deoxygenated. 3 Blood pressure Pressure is high Pressure is low Pressure is extremely low 4 Blood flow Blood flows rapidly with jerks Blood flows smoothly without jerks .. Blood flows smoothly without jerks 5 Lumen Narrow Wide Very small 6 valves Absent Present Absent 7 Location Mostly deep seated . Mostly superficial Form a network all over the body and in the organs. Lymphatic System • The human circulatory system consists of another body fluid called lymph. It is also known as tissue fluid. • It is produced by the lymphatic system which comprises a network of interconnected organs, nodes, and ducts. • Lymph is a colorless fluid consisting of salts, proteins, water, which transport and circulates digested food and absorbed fat to intercellular spaces in the tissues.
  • 7. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE • Unlike the circulatory system, lymph is not pumped; instead, it passively flows through a network of vessels. Excretion in Human Beings & Plants EXCRETION : The biological process of removal of harmful nitrogenous wastes from the body is called excretion. The waste products in animals include: (i) Nitrogenous compounds like ammonia, urea and uric acid. (ii) Carbon dioxide and water. (iii) Excess salts and vitamins. (iv) Unwanted medicines. Ammonotelic organisms are those which excrete ammonia. e.g. most aquatic animals. Ureotelic organisms are those which excrete urea. e.g. sharks, frogs, mammals. Uricotelic organisms are those which excrete uric acid. e.g. birds, insects, land snails, many reptiles. Excretory Organs/Structures in Animals: - Animals Amoeba Hydra Flatworm Earthworm Insects e.g. cockroach All chord ates Excretory Structures Cellular surface Body surface Protonephridia (flame cells) Nephridia Malpighi an tubules Kidneys Waste products CO2 and ammonia CO2 and ammonia Mainly ammonia ammonia and urea Uric acid Uric Acid Urea HUMAN EXCRETORY SYSTEM: Human excretory system consists of: - – A pair of kidneys – A pair of ureters. – Urinary bladder. – Urethra KIDNEY :
  • 8. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE • The main excretory organ of our body are kidneys.  HUMAN EXCRETORY SYSTEM > The excretory system collects the liquid wastes of the body and removes them. > The excretory system of human consists: o Two kidneys o Two ureters o Bladders o Urethra o Bean shaped organs towards back of our body just above the waist. o Every person has two kidneys. Colour – Dark red Shape – Bean shaped Weight – 125–170 gms. Size – 10 cm length, 5 cm breadth, 3 cm thickness. Position – Located lateraly either sides of vertebral column. External Structure: - • Each kidney is surrounded and covered by a tough, fibrous, capsule of connective tissues. This capsule is called renal capsule. • Lateral surfaces of kidney are convex while medial surfaces are concave. • Each kidney is made up of a large number (10 lakhs) of excretory units called Nephrons. • The human kidney is not located at similar positions due to presence of liver above right kidney, so the right kidney get slightly lower position. Internal Structure: • The internal structure of kidneys can be divided into two parts. • Its outer part is called cortex and inner part is called medulla. • Nephron is the structural and functional unit of excretion. • A nephron consists of a long coiled tubule differentiated into proximal nephron, loop of Henle and distal nephron. The latter opens into the collecting tubule. • At the proximal end of the nephron, a double walled cup-shaped structure is present called Bowman's capsule. • It consists of network of capillaries called glomerulus. • One end of the glomerulus is attached to renal artery and the other end to the renal vein. • In the glomerulus, blood comes in through afferent arteriole and blood is drained out through efferent arteriole. • Glomerulus and Bowman capsule are collectively called Malpighian body or renal corpuscle. • Structure of Nephron: - • Nephron is the structural and functional unit of kidney, which is about 3 cm long and 20-60 μm in diameter.
  • 9. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE • Each kidney has about one million nephrons in humans. A nephron can be divided into three regions: • The function of glomerulus is to filter the blood passing through it. This process is called ultrafiltration. (I) Proximal nephron (Bowman's capsule + Proximal convoluted tubule) (II) Loop of Henle (Ascending + Descending limb) (III) Distal nephron (Distal convoluted tubule which opens into collecting duct) (I) Proximal nephron: Nephron tubule is closed at its proximal (starting) end but its distal end is open and continues into the loop of Henle. At the proximal or closed end the nephron is expanded and curved inwardly to form a double-walled cup shaped Bowman's capsule. Within the Bowman's capsule a network or tuft of capillaries is present, it is called glomerulus. Diameter of afferent arteriole is greater than efferent arteriole. (II) Loop of Henle: It starts after the proximal convoluted tubule, It ends before the distal convoluted tubule. This hairpin like loop has a descending limb, followed by an ascending limb. (III) Distal nephron: The ascending limb of Henle's loop merges into distal convoluted tubule. The distal convoluted tubules of a number of adjacent nephrons open into a common collecting duct or tubule. Ureter: • The collecting ducts open into the ureter. • Each ureter originates from interior part of kidney. • The anterior part of the ureter is broad, like a funnel and called pelvis and its posterior part is in the form of long tubule. Urinary Bladder: • Each ureter opens into the urinary bladder. • The structure of urinary bladder is muscular sac like and pear shaped. • Its wall is flexible, it collects urine when necessary by the contraction of muscles, the urine is excreted through urethra.
  • 10. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE Urethra: It is a muscular and tubular structure, which extends from the urinary bladder to the outside. It carries the urine to the outside. Micturition: Micturition is the term used for urination. (Passing out of urine) Functions of Kidney: > Regulation of water and electrolyte balance. (Osmoregulation) > Regulation of acid base balance. > Regulation of blood pressure. > Excretion of metabolic waste and foreign chemicals. Physiology of Excretion: - > The impure blood enters to each kidney through renal artery. > The afferent arterioles which is branch of renal artery provides blood to the glomerulus. > Glomerulus is a group of blood capillaries formed by division of afferent arterioles located in Bowman capsule. > The arterioles which carry blood away from glomerulus are called efferent arterioles. > The radius of afferent arterioles is greater than that of efferent arterioles so the pressure in glomerulus increases which is necessary for ultrafiltration. > Due to the blood pressure, water, glucose, urea, uric acid and some salt from the blood of afferent arteriole filter in Bowman capsule through ultra-filtration. > It also contains glucose, amino acid and some useful salts along with filtrate. > This liquid from the Bowman capsule moves through the glandular part of the nephron. > From glucose, useful salt and some part of water is reabsorbed. The amount of water reabsorbed depends on how much excess water there is in the body and on how much of dissolved waste there is to be excreted. > The remaining liquid now contain only waste material is called urine. > The urine from the nephron is collected in urinary bladder through ureter. > Urine is stored in the urinary bladder until the pressure of the expanded bladder leads to the urge to pass it out through the urethra. > By the contraction of muscles of urinary bladder, the urine passes out of the body when necessary. > All the systems of our body keep the internal environment stable even on the changing conditions of external environment. > Usually the homeostatic activities are performed by excretory organ. > They not only excrete out salts and nitrogenous waste products but also perform important role of water balance.
  • 11. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE Osmoregulation: - The process of maintaining the right amount of water and proper ionic balance in the body is called osmoregulation. Urine Formation: - It involves three processes: glomerular filtration (ultrafiltration), tubular reabsorption and tubular secretion. (1) Ultrafiltration: - > Walls of glomerulus and Bowman's capsule are thin and semipermeable membrane. In the glomerulus there are many minute pores present. > Afferent arteriole is wider and releases the blood into glomerulus, whereas efferent arteriole is narrow. Thus, there is development of high blood pressure. > Due to this pressure, separation of small, selective molecules ions from the large molecules in the blood occurs and called ultrafiltration. > Fluid which is filtered out from the blood is called as glomerulus filterate / capsular filtrate / ultrafiltration. (2) Tubular Reabsorption: - > The ultrafiltration contains salts, glucose, amino acids, urea, uric acid and large amount of water. > Glucose, salts, amino acids and water are reabsorbed by various parts of nephron and finally they enter into the surroundings blood capillaries. (3) Tubular secretion: - It is removal of wastes from the surrounding blood capillaries into the glomerular filtrate. Glomerular filtrate entering collecting duct is called urine. Urine composition is different from filtrate by the loss as well as gain of many substances during the course of nephrons. Chemical composition of urine: > Urine is slightly acidic liquid, light yellow in colour. > The healthy human being has 95% water, 5% urea, uric acid and salts of phosphoric acid. > A young and healthy person excretes 1.5-1.8 liters’ urine per day. > This quantity may increase due to intake of tea, coffee, wine etc.  Role of lungs in excretion: Human lungs eliminate around 18L of CO2 per hour and about 400ml of water per day in normal resting condition. Water loss via the lungs is small in hot humid climate and large in cold dry climates.  Role of skin in excretion: - Human possess two types of glands on skin; (1) Sweat glands: - These excrete sweat, contain 99.5% Water, NaCl, Lactic acid, Urea, Amino acid and glucose. (2) Sebaceous glands: - These secrete sebum which contain waxes, sterols, hydrocarbons and fatty acids.  Role of liver in excretion: -
  • 12. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE > Liver is the main site for elimination of cholesterol, bile pigments, inactivated products of steroid hormones, some vitamins and many drugs. Bile carries these materials to the intestine from where they are excreted with the faeces.  ARTIFICIAL KIDNEY OR HAEMODIALYSIS > Kidney dialysis also known as hemodialysis or renal dialysis, is a medical treatment used to remove nitrogenous waste materials from the blood of patients lacking kidney function or kidney failure, due to infections, injury or restricted blood flow to kidneys. > In this procedure, the blood is circulated through a machine known as artificial kidney or dialyser that removes wastes and excess fluid from the bloodstream. > The blood from an artery is pumped through a dialyser or artificial kidney, where it flows through a semipermeable membrane which removes unwanted elements in the blood by diffusion. > The blood is then returned to the body through a vein. > Main difference of kidney & dialysis is that there is no reabsorption in dialysis. > In kidney, initial filtrate is about 180L daily but actual excretion is only a liter or two a day. Excretion • All the living organisms perform various biochemical reactions and produce toxic . • If these toxic substances accumulate in body harms an organism, so for normal working an organism, removal of these toxic substances from the body is necessary. • The process of removal of toxic wastes from the body of an organism is called excretion. > Excretion in Plants. • Plants produce a number of waste products during their life processes. • The plants remove their waste products by different methods. > Gaseous excretion: - • The main products produced by plants are carbon dioxide, water and oxygen. • Carbon dioxide and water vapour are produced during respiration by plants whereas oxygen is produced as a waste during photosynthesis. • The gaseous wastes of respiration and photosynthesis in plants carbon dioxide, oxygen and water vapour are removed through stomata in leaves and lenticels in stems and released in air. • The plants excrete carbon dioxide produced as a waste during respiration only at night time. • As during the day time carbon dioxide released during respiration is being used during the process of photosynthesis. • The excrete oxygen and water vapour as waste during day time. • The removal of Water vapour during day through stomata is called transpiration.
  • 13. EXCELLENT CLASSES STD – 10 CHAPTER – 5 SUB :- SCIENCE > Other wastes: - • The plants also store some of the waste from their body parts like leaves, fruits and bark of trees. • The remove these wastes by shedding of leaves, felling of fruits and peeling of bark. • When the dead leaves bark and ripe fruits fall off from trees, then the waste products contained in them are also removed. • The plants also secrete their wastes in the form of gum and resins from their stems and branches • The plants also excrete some waste substances into the soil and around them. Summary • The plants get rid of gaseous waste products through stomata in leaves and lenticels in stem. • The get rid of stored solid and liquid wastes by the shedding of leaves, peeling of bark and felling of fruits. • The get rid of wastes by secreting them in the form of gum and resins. • Plants also excrete some waste substances into soil around them. Excretion in Animals. • Different animals have different arrangements (organs) for excretion of waste. • In Amoeba and other single cellular organisms o In Amoeba and other single cellular organisms remove carbon dioxide by diffusion through the cell membrane. o Nitrogenous wastes and excess water are removed by the contractile movement of vacuole. • In earthworm, > The tubular structures called nephridia are the excretory organs. > The moist skin also acts as an excretory organ. • In human and other mammals > The microscopic thin tubules form nephron, which works as excretory unit and remove nitrogenous substances. > Carbon dioxide produced during respiration is removed. > Skin also removes salt and water by sweating.  Removal of waste products in Human. > The major wastes produced by human body are carbon dioxide and Urea. > Carbon dioxide is produced as a waste by the oxidation of food during respiration. > Human lungs excrete carbon dioxide. > Kidneys excrete urea.