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IRJET- Automated Detection of Diabetic Retinopathy using Compressed Sensing
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1.
International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4752 AUTOMATED DETECTION OF DIABETIC RETINOPATHY USING COMPRESSED SENSING Sreelakshmi B1, Mr.S.Mohan2, Dr.V.Jayaraj3 1PG Scholar,Dept. of Electronics &Communication Engineering,Nehru Institute of Engineering & Technology 2Assistant Professor,ECE Department Nehru Institute of Engineering and Technology, 3Professor & Head,ECE Department Nehru Institute of Engineering and Technology ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - Eye diseases are rapidly increasing day by day. Retinal diseases are the major reason to damage the visual parts of the eye .The main aim of the proposed work is to find out the disease such as increase in blood pressure, diabetic retinopathy, glaucoma, retinal tear and retinal detachment and cardio-vascular diseases. These diseases can be found by the extracted blood vessels. Hypertension in the body leads to the damage in the retinal blood vessels. Tear in the visual parts may leads to the loss of visual perception in the human beings. Diabetic retinopathy diseases can be identified at the early stages by using image processing techniques. Thus the early stage of rectification may leads to smaller damage than the risky ones. Thus the proposed work leads to the identification of retinal diseases with the certain level of accuracy and sensitivity. Key Words: Diabetic Retinopathy,Segmentation, Compressed Sensing,Classification 1.INTRODUCTION More commonly, training a convolutional neural community requires big numbers of labeled training data, which is someway very tricky to realize in the medical domain where the proficient annotation is steeply-priced and the ailments are infrequent. For a project such like the retinal bloodvesselsegmentation, the whole number of the retinal color graphics fromall the four databases is 133, which is a long way far from the learning requirement of the fully convolutional community. Nevertheless, with transfer learning, the convolutional neural community models pre-trained from nor[1] mal picture dataset,suchasImageNet,can be used for the new clinical venture at hand. There are threeprogressivefeatureswhichhaveeventuallymade this proposed work triumphant. First, the proposed procedure has shifted, or in one more phrase, simplified the normal retinal vessel segmentation quandary from full-dimension photograph segmentation to regional vessel detail awareness.This is to assert, vessel pixels are to be recognized from neighbourhood to vicinity and merged collectively ultimately. 2d, due to the fact that of this main issue moving, the training information, for that reason, can be augmented from a hundred to a hundred thousand, which ensures the effectiveness of deep network coaching. 0.33, the correct system offine tuning the pretrained semanticsegmentationmodelhasmadethe regional segmentation assignment so much simpler. This pre-expert semantic segmentation mannequin is the completely convolutional variantofAlexNet,which good performs the pixel-to-pixel and end-to-finish segmentation. In the following sections, this paperwill additional present and talk about the implementation of the proposed process.The retinal vasculature has been mentioned 2.LITERATURE SURVEY: In an attempt to provide a tremendously correct and robust automatic retinal blood vessel segmentation method, this paper, for this reason, proposes an innovativesupervisedmethodtoextractretinalvessels utilising deep studying tactics. More principally, the proposed method has applied the absolutely convolutional community, which is most of the time used to perform semantic segmentation undertaking, with transfer studying. Deep studying is an development of man-made neural networks, such as extra layers that let higher stages of characteristic abstraction and elevated predictions from information(2).Exceptionally,theconvolutionalneural network has proventobeapowerfulsoftwareforquite a lot of of pc imaginative and prescient tasks comparable to photo classification and segmentation. Recently, scientific picture evaluation organizations across the world are rapidly coming into thisfield and
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International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4753 makinguseofconvolutionalneuralnetworksandother deep studying methodologies to a vast style of functions, and distinctive results are rising continuously (3).The totallyconvolutionalcommunity, proposed by using the pc imaginative and prescient staff of the tuition of California, Berkeley(4),isderived from the convolutional neural network, which, in concept, is on the whole constructed from a number of convolutional layers (5) and thenfollowedbymeansof a number of entirely linked layers as in a general multilayer neural network. The principal function that makes a entirely convolutional network special from the convolutional neural community is the transformation of all wholly connected layers into convolution layers .It was way of which, a absolutely convolutional communityis equipped to operateonan input of any measurement, and produces an output of corresponding spatial dimensions. In this case, some classification networks, such as the AlexNet (6), canbe used for the end-to-finish, pixels-to-pixelsforsemantic segmentation, as a substitute of outputting the classification prediction scores. Within the work of Shelhamer et al. (7), the fully convolutional variant of AlexNet excels the entire other brand new works with out further machinery, which is consequently applied in the proposed work along with the transfer finding out methodology.Switchstudyingistheperfectanswer when there have inadequate paper is as follows. Section2will introduce theretinalimagedatabasesand the associated works. Part three will exhibit the proposedimplementationofknowledgeaugmentation, the training of the utterly convolutional community, and publish-processing. 3.PROPOSED WORK Image processing consists of various stages of processing. The main stage of image processing consists of image acquisition, pre-processing, segmentation, feature extraction and classification. Figure 1.Basic block of image processing The block diagram of the proposed work is as follows. Figure.2 Proposed block diagram A) IMAGE ACQUISITION: Retinal fundus images are the interiorsurfaceof the eye. It specifies opposite portion of lens include retina, optic disc, macula, fovea and posterior pole. These images should examine and verified by ophthalmoscopy. Figure.3 Input image
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International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4754 B) PRE-PROCESSING: Pre processing stage consists of color conversion and filtering process.The input retinal images can be in the form of RGB images.These RGB images are converted into gray scale images.RGB images are converted into gray scale images due to the elimination of hue and saturation of the input images. Figure.3 Gray-scale conversion C) MEDIAN FILTER The median filter works by moving through the image pixel by pixel, replacing each value with the median value ofneighbouringpixels.Thepatternofneighbours is called the "window", which slides, pixelbypixelover the entire image. The median is calculated by first sorting all the pixel values from the window into numerical order, and then replacing the pixel being considered with the middle (median) pixel value.Itisa nonlinear digital filter used to remove some noise in the image. Figure.4 Filtered image D) CHANNEL EXTRACTION This stage is used to separate the green channel of the fundus image. Figure.4 Green channel extraction This histogram equalization is used to equalize the intensity level of the converted gray-scale image. Figure.5 Histogram equalization E) MORPHOLOGICAL OPERATIONS There are several morphological operationspresentin image processing techniques.The main morphological operations used in the proposed work is opening,closing,top hat and binarization. OPENING: Opening of the binary image is used to carried out the extraction of minute blood vessels within the fundus images. Figure.6 Opening
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International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4755 F) Compressed Sensing Compressive Sensing (CS) has attracted considerable attention in areas of applied mathematics, computer science, and electrical engineeringbysuggestingthatit may be possible to surpass the traditional limits of sampling theory. CS is the theory of reconstructing large dimensional signals from a small number of measurements by taking advantage of the signal sparsity. CS builds upon the fundamental fact that can represent many signals using only a few non-zero coefficients in a suitable basis or dictionary. CS has been widely used and implemented in many applicationsincludingcomputedtomography,wireless communication, image processing . G) OSTU SEGMENTATION OD Is the largest bright circle in the Image. OD Detection allows eliminating the background and its destructive effects on the proposed method. Morphological operations are appliedto get better quality image After the image enhancement the reconstructed image consist only the brighter pallets or regions with higher intensities. i.e. OD and exudates lesions. The morphological reconstruction operation enhancesthecompactnessofbrightlyilluminated regions that include bright lesions, OD and contrast variations around the blood vessels. H) EXTRACTION OF TEXTURE FEATURES GLCM can be an m x n x p array of valid gray-level co occurrence matrices. Each gray-level cooccurrencematrixisnormalizedsothatitssum is one. Propertiescanbeacommaseparatedlistof strings, a cell array containing strings, the string 'all', or a space separated string. They can be abbreviated, and case does not matter. A Gray Level Co-Occurrence Matrix (GLCM) has information regarding the position of pixels possessing similar gray level values. I) BINARIZATION: Gray scale images are converted into binary-scale as their pixels value ranges from 0’s and 1’s.These pixel value is used to separate the meaningfulpartsfromthe unnecessary parts in the fundus image. Figure.9 Binary image J) CLASSIFICATION: From the extracted blood vessels we can able to classify the artery veins of the fundus retinal images.These extracted blod vessels is used to classify the person having the cardiac disease or normal.This classification is carried out using SVM classifier. Figure 9 Segmentation
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International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4756 K) CLASSIFIERS The classification process is carried out using PNN classifiers.training and testing of retinal images is carried out using Neural Network (PNN).The PNN classifiers consists of 10,000 neurons and 3 hidden layers. Figure.10 classification 4 PERFORMANCE MEASURE: Performance measure is the calculation of accuracy,sensitivity,specificity.Accuracy,sensitivity,spe cificity can be calculated from the true positive and true negative valuesoftheclassifiedandnon-classified images. Figure.11 Performance measure Figure.12 Accuracy plot Figure.13 Sensitivity plot Figure.14 Specificity plot 5 CONCLUSION Thus the eye disease of the human are recognized using the image processing techniques which executes the accuracy range of 90% and the error rate will be lesser. 6 FUTURE WORK: Many retinal disease will be found using these image processing technique.In the future work,many disease are found at the lesser time.This will be used for the real time analysis.This will be used for analysis and diagnosis of retinal images. REFERENCES: Abdurrazaq, I., Hati, S., Eswaran, C., 2008. Morphology approach for features extractionin retinal images for diabetic retionopathy diagnosis. In: Proceedings of th International Conference on Computer and Communication Engineering 2008.ICCCE08: Global Links for Human Development. pp. 1373–
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International Research Journal
of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 06 Issue: 05 | May 2019 www.irjet.net p-ISSN: 2395-0072 © 2019, IRJET | Impact Factor value: 7.211 | ISO 9001:2008 Certified Journal | Page 4757 1377.http://dx.doi.org/10.1109/ICCCE.2008.458083 0. Al-Diri, B., Hunter, A., Steel, D., Habib, M., Hudaib, T., Berry, S., 2008. Review–a reference data set for retinal vessel profiles. In: 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE. pp. 2262– 2265.http://dx.doi.org/10.1109/IEMBS.2008.46496 47. Azzopardi, G., Strisciuglio, N., Vento, M., Petkov, N., 2015. Trainable cosfirefilters for vessel delineation with application to retinal images. Med. Image Anal. 19 (1), 4657.http://dx.doi.org/10.1016/j.media.2014.08.00 2. Z. Jiang et al. Computerized Medical Imaging and Graphics 68 (2018) 1–15 Ordonez, R., Massin, P., Erginay, A., Charton, B., Klein, J.-C., 2014. Feedback on a publicly distributed database: the messidor database. Image Anal. Stereol. 33 (3),231– 234.http://dx.doi.org/10.5566/ias.1155. Deep learning–MIT technology review.https://www.technologyreview.com/s/5136 96/deep-learning/. Fraz, M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A., Owen, C., Barman, S.,2012a. Blood vessel segmentation methodologies in retinal images–a survey. Comput. Methods Programs Biomed. 108 (1), 407– 433.http://dx.doi.org/10.1016/j. cmpb.2012.03.009. Fraz, M.M., Remagnino, P., Hoppe, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G., Barman, S.A., 2012b. An ensemble classification-based approach applied to retinal blood vessel segmentation. IEEE Trans. Biomed. Eng. 59 (9), 2538– 2548.http://dx.doi.org/10.1109/TBME.2012.220568 7. Fraz, M.M., Barman, S.A., Remagnino, P., Hoppe, A., Basit, A., Uyyanonvara, B., Rudnicka, A.R., Owen, C.G., 2012c. An approach to localize the retinal blood vessels using bit planes and centerline detection. Comput. Methods Programs Biomed. 108 (2), 600– 16.http://dx.doi.org/10.1016/j.cmpb.2011.08.009.F u, H., Xu, Y., Wong, D.W.K., Liu, J., 2016. Retinal vessel segmentation via deep learning network and fully- connected conditional randomfields. 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI) 698– 701.http://dx.doi.org/10.1109/ISBI.2016.7493362. Greenspan, H., van Ginneken, B., Summers, R.M., 2016. Guest editorial deep learning in medical imaging: overview and future promise of an exciting new technique. IEEE Trans. Med. Imaging 35 (5), 1153– 1159.http://dx.doi.org/10.1109/TMI.2016.2553401. arXiv:1603.05959. Jiang, Z., Yepez, J., An, S., Ko, S., 2017. Fast, accurate and robust retinal vessel segmentation system. Biocybern. Biomed. Eng. 37 (3), 412– 421.http://dx.doi.org/10. 1016/j.bbe.2017.04.001. Kohler, T., Budai, A., Kraus, M.F., Odstrcilik, J., Michelson, G., Hornegger, J., 2013.Automatic no- reference quality
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