2. AN EPIDEMIC MODEL FOR INFLUENZA
Population divided into three groups:
S(t) : those Susceptible to catching the disease
I(t) : Those infected with the disease and capable of spreading it
R(t) : Those who have recovered and are immune from the disease
Assumption :
The populations of susceptibles and contagious infectives are large
so that random differences between individuals can be neglected.
Birth and death in this model are ignore
The disease spread by contact.
The latent period are neglected, settingg it equal to zero
People who recover from the disease are then immune.
At any time, the population is homogeneously mixed, i.e we assume
that contagious infectives and susceptibles are always randomly
distributed over the area in which the population lives.
3. COMPARTMENT DIAGRAM
infectives recoveredsusceptibles
recoveredinfected
𝑟𝑎𝑡𝑒 𝑜𝑓
𝑐ℎ𝑎𝑛𝑔𝑒 𝑖𝑛 𝑛𝑜.
𝑠𝑢𝑠𝑐𝑒𝑝𝑡𝑖𝑏𝑙𝑒𝑠
= −
𝑟𝑎𝑡𝑒
𝑠𝑢𝑠𝑐𝑒𝑝𝑡𝑖𝑏𝑙𝑒𝑠
𝑖𝑛𝑓𝑒𝑐𝑡𝑒𝑑
𝑟𝑎𝑡𝑒 𝑜𝑓
𝑐ℎ𝑎𝑛𝑔𝑒 𝑖𝑛 𝑛𝑜.
𝑖𝑛𝑓𝑒𝑐𝑡𝑖𝑣𝑒𝑠
=
𝑟𝑎𝑡𝑒
𝑠𝑢𝑠𝑐𝑒𝑝𝑡𝑖𝑏𝑙𝑒𝑠
𝑖𝑛𝑓𝑒𝑐𝑡𝑒𝑑
−
𝑟𝑎𝑡𝑒
𝑖𝑛𝑓𝑒𝑐𝑡𝑖𝑣𝑒𝑠
ℎ𝑎𝑣𝑒 𝑟𝑒𝑐𝑜𝑣𝑒𝑟𝑒𝑑
𝑟𝑎𝑡𝑒 𝑜𝑓
𝑐ℎ𝑎𝑛𝑔𝑒 𝑖𝑛 𝑛𝑜.
𝑟𝑒𝑐𝑜𝑣𝑒𝑟𝑒𝑑
=
𝑟𝑎𝑡𝑒
𝑖𝑛𝑓𝑒𝑐𝑡𝑖𝑣𝑒𝑠
ℎ𝑎𝑣𝑒 𝑟𝑒𝑐𝑜𝑣𝑒𝑟𝑒𝑑
𝑑𝑆
𝑑𝑡
= −𝛽𝑆 𝑡 𝐼(𝑡)
𝑑𝐼
𝑑𝑡
= 𝛽𝑆 𝑡 𝐼 𝑡 − 𝛾𝐼(𝑡)
𝑑𝑅
𝑑𝑡
= 𝛾𝐼(𝑡)
• 𝛽 is called the transmission coefficient or infection rate
• 𝛾 is recovery rate or removal rate. (𝛾−1
is average time that an
individual infectious)
𝑆 0 = 𝑠0, 𝐼 0 = 𝑖0, 𝑅 0 = 0
4. THE BASIC REPRODUCTION NUMBER
The basic reproduction number 𝑅0 is defined as the number of new
secondary infections resulting from a single infectious individual placed in a
completely susceptible population, over the time that individual is infectious.
If 𝑅0 < 1 we would expect the disease outbreak to die out (I(t) to decrease)
If 𝑅0 > 1 then it would increase initially
5. SIMULATION
𝑅0 =
𝛽𝑆(0)
𝛾
If we vaccinate a proportion 𝑝 of the population of susceptible then this
means that the basic reproduction number changes to
𝑅 𝑣 =
1 − 𝑝 𝛽𝑆(0)
𝛾
= (1 − 𝑝)𝑅0
To eradicate the disease, 𝑅 𝑣 < 1, then 𝑝 > 1 −
1
𝑅0
.
6. ENDEMIC DISEASE
𝑎 denote the natural per capita death rate of population
𝑏 denote the natural per capita birth rate of population
𝑁 𝑡 = 𝑆 𝑡 + 𝐼 𝑡 + 𝑅 𝑡
𝑑𝑁
𝑑𝑡
= 𝑏 − 𝑎 𝑁
If 𝑏 = 𝑎 the the population remains constant.
I(t) R(t)S(t)
recoveredinfectedbirths
deaths deaths deaths
𝑑𝑆
𝑑𝑡
= 𝑏𝑁 − 𝛽𝑆𝐼 − 𝑎𝑆
𝑑𝐼
𝑑𝑡
= 𝛽𝑆𝐼 − 𝛾𝐼 − 𝑎𝐼
𝑑𝑅
𝑑𝑡
= 𝛾𝐼 − 𝑎𝑅
7. PREDATORS AND PREY
Assumption :
The population are large, sufficiently large to neglect random
differences between individuals.
The effect of pestiside initially are ignored
There are only two populations, the predator and the prey, which
affect the ecosystem.
The prey population grows exponentially in the absence of predator.
PREY
PREDATORS
Natural births
births
Natural deaths
Deaths from predators
Natural deaths
8. SYSTEM OF EQUATION
Let 𝛽1 = 𝑏1 − 𝑎1, −𝛼2 = 𝑏2 − 𝑎2, dan 𝑐2 = 𝑓𝑐1𝑑𝑋
𝑑𝑡
= 𝑏1 𝑋 − 𝑎1 𝑋 − 𝑐1 𝑋𝑌
𝑑𝑌
𝑑𝑡
= 𝑏2 𝑌 + 𝑓𝑐1 𝑋𝑌 − 𝑎2 𝑌
𝑑𝑋
𝑑𝑡
= 𝛽1 𝑋 − 𝑐1 𝑋𝑌
𝑑𝑌
𝑑𝑡
= 𝑐2 𝑋𝑌 − 𝛼2 𝑌
𝑐1 dan 𝑐2 are known as interaction parameters
The systems of equations is called the Lotka-Voltera predator-prey systems
10. COMPETING SPECIES
Assumption :
The population to be sufficiently large so that random fluctuations
can be ignored without consequences
The two species model reflects the ecosystem sufficiently accurately.
Each population grows exponentially in the absence of the other
competitor
Species X
Species Y
births
births deaths
deaths
𝑑𝑋
𝑑𝑡
= 𝛽1 𝑋 − 𝑐1 𝑋𝑌
𝑑𝑌
𝑑𝑡
= 𝛽2 𝑌 − 𝑐2 𝑋𝑌
𝛽1 and 𝛽2 where per capita growth rates which
incorporating deaths (independent of the other species)
𝑐1 and 𝑐2 are the interaction parameters
Gause’s Equations
12. MODEL OF BATTLE
Assumption :
The number of soldiers to be sufficiently large so that we can neglect
random differences between them
There are no reinforcements and no operational losses (i.e due to
desertion or disease)
Red soldiers
Blue soldiers
deaths
deaths
For aimed fire the rate of soldiers wounded is proportional to the number of
enemy soldiers only
For random fire the rate at which soldiers are wounded is proportional to
both numbers of soldiers
𝑑𝑅
𝑑𝑡
= −𝑎1 𝐵
𝑑𝐵
𝑑𝑡
= −𝑎2 𝑅
𝑎1 and 𝑎2 are measure the effectiveness of the
blue army and red army respectively (called
attrition coefficients)