PROF. SANDEEP PARIYANI
DEPARTMENT OF E&C,
DHAVAL B. MAJITHIA
PARTH M. JAKHRIYA
SAGAR V. TAMALIYA
A sensor that integrates a biological element with a
physiochemical transducer to produce an electronic signal
proportional to a single analytic which is then conveyed to a
A Biosensor is a self-contained Integrated Device that is capable
of providing specific quantitative or semi- quantitative analytical
information using a bio logical element which is contact with a
This is a device that uses specific biochemical reaction to detect
chemical compound in biological compound.
FATHER OF BIO SENSOR
Leland C. Clark Jr. (1918–2005) was
an American biochemist born in
He is most well known as the
inventor of the Clark Electrode, a
device used for measuring oxygen in
blood, water and other liquids.
Professor Leland C Clark Jnr
LINEARITY: Linearity of the sensor should be high for the detection
of high substrate concentration.
SENSITIVITY: The Value of the electrode response per substrate
SELECTIVITY: Chemicals Interference must be minimized for
obtaining the correct result.
RESPONSE TIME: Time necessary for having 95% of the response.
COMPONENTS OF BIOSENSOR
The Three main components of biosensors are:
•Biological element: For sensing the presence and concentration of a
•Transducer: The product of interaction of biological component and
sample may be a suitable chemical, charge etc., which can be
converted by transducer into an electrical signal.
•Associated Electronic Devices: The electrical signal may be further
amplified and can be read on digital panels
Glucose Monitoring Device
Glucose Monitoring Device is used to
monitors the glucose level in the blood.
It is mostly useful for diabetes patient to
know his/her diabetes level so the doctor
treat them well as soon as possible.
It is a pulse proximetry, i.e. it monitors the
oxygen saturation. It is based on the concept of
Blood pressure pulse causes vessel wall
displacement. Detection pulsatile blood volume
changes by photoelectric method by photo
resistor Connected as a part of voltage divider
circuit and produces a voltage that varies with the
amount of blood in the finger.
WORKING OF RING SENSOR
In order to detect blood volume changes due to heart contraction and
expansion by photoelectric method, normally photo resistors are used.
Light is emitted by LED and transmitted through the artery and the
resistance of photo resistor is determined by the amount of light reaching it.
Oxygenated blood absorb more light than deoxygenated blood
A noise cancellation filter is used to cancel the noise due to motion of the
Easy to use.
Reducing hospitalization fee
Initial cost is high.
Limited number of physiological
parameters can be monitored.
It is also known as GTWM i.e. Georgia
Tech Wearable Motherboard.
This GTWM (smart shirt) provides an
extremely versatile framework for the
incorporation of sensing, monitoring
and information processing devices.
.It is used to integrate sensors for monitoring the vital signs like
temperature, heart rate and respiration rate.
It uses optical fibers to detect bullet wounds and special sensors and
interconnects to monitor the body vital signs during combat conditions
WORKING OF SMART SHIRT
A combat soldier sensor to his body, pulls the smart shirt on, and attaches
the sensors to the smart shirt.
A “signal” is sent from one end of the plastic optical fiber to a receiver at the
other end. The emitter and the receiver are connected to a Personal Status
Monitor (psm) worn at the hip level by the soldier.
If the light from the emitter does not reach the receiver inside the PSM, it
signifies that the smart shirt has been penetrated (i.e.; the soldier has been
The signal bounces back to the PSM forum the point of penetration, helping
the medical personnel pinpoint the exact location the solider wounds.
Right Treatment at the right time
Easy to wear and takeoff.
Initial cost is high
Battery life is less
Study of biomolecules and their interaction
Environmental field monitoring
Industrial Process Control
Detection systems for biological warfare agents
Manufacturing of pharmaceuticals and replacement organs
Detection of toxic metabolites such as fungi
Remote sensing of airborne bacteria e.g. in counter-bioterrorist activities
It is applied to restricted area of potential market.
The limitations is Sensitivity And battery life.
This is advanced technologies such as the smart shirt have at partial to
dramatically alter its landscape of healthcare delivery and at practice of
medicine as we know them today.
It is leading to the realization of “Affordable Healthcare, Any place,