This document discusses common age-related changes that occur in the cells and various body systems as people age. It describes changes at the cellular level like reduced cell numbers and lean body mass. It also reviews changes in physical appearance like hair loss, wrinkles and reduced tissue elasticity. Finally, it examines changes that can occur in major body systems including the respiratory, cardiovascular, gastrointestinal and urinary systems which can impact health and increase risk of issues like infection, falls and more. Nursing interventions are discussed for many of the changes.