THIS PPT IS FOR II YEAR DIPLOMA OTT & DT STUDENTS PHARMACOLOGY ; DRUG DOSAGE FORMS & POSOLOGY

1. MEGHANA CHANNAPPA
DOTT, BOTT, M.Sc Medical
Biochemisry
DOSAGE FORMS OF DRUGS
&
POSOLOGY

2. INTRODUCTION
Dosage form (Medicines) = API + Excipients
The means (or the form) by which drug molecules are
delivered to sites of action within the body.
Drug (Active pharmaceutical ingredients )
Chemical compound intended for used in diagnosis,
treatment prevention, of disease. (OR) The Active
Pharmaceutical Ingredient (API) is the part of any drug that
produces its effects.
Excipients
 Do not increase or affect the therapeutic action of the active
ingredient,.
 Inactive ingredients may also be referred to as inert
ingredients or excipients, and generally have no
pharmacological effect.

3. THE NEED FOR DOSAGE
FORMS
Accurate dose.
Protection e.g. coated tablets, sealed ampules.
Protection from gastric juice.
Masking taste and odour.
Placement of drugs within body tissues.
Sustained release medication.
Controlled release medication.
Optimal drug action.
Insertion of drugs into body cavities (rectal,
vaginal)

15. POSOLOGY
POSOLOGY
It is the science of dosage. It deals with the
amount of drug necessary to produce a desired
physiological, therapeutic, or prophylactic effect.
MINIMUM DOSE
The minimum dose is considered the smallest
dose of drug that that produce the therapeutic
effect.
MAXIMUM DOSE
The maximum dose is considered the large dose
of drug that can be safely administered.

16. POSOLOGY
TOXIC DOSE
The toxic dose of a drug is considered the
amount of drug that will produce noxious or
harmful effect.
LETHAL DOSE “LD50”
The lethal dose of a drug is the amount of
substance that will cause death
SINGLE DOSE
It is the amount of that substance to be taken at
one time.

17. POSOLOGY
DAILY DOSE
The daily dose of a drug is the amount of that
substance to be taken in a 24 hour period.
MAINTAINCE DOSE
The maintenance dose of a drug is the amount of
that substance taken to maintain or continue a
desired therapeutic effect.

18. Meghs C