A 55-year-old woman experienced her first syncope incident while on holiday abroad. Tests including CT scans of her chest, abdomen, and mammography did not reveal any abnormalities. An MRI of her head showed a lesion with edema in her left frontal lobe, which was later confirmed to be a brain tumor after she returned to Poland. She underwent a craniotomy to resect the tumor, and a biopsy revealed glioblastoma multiforme (GBM). After the operation, she received chemotherapy with Temodal and radiotherapy. Follow-up MRIs did not show any new metastases. GBM remains a significant cause of morbidity and mortality from brain tumors, but interdisciplinary therapy can prolong survival time after surgery.

1. Maria Krówka, Sylwia Wyleciał, Justyna Kocór, Justyna
Lewandowska, Karolina Sypel
Students’ Scientific Society, Department of Radiology and Nuclear Medicine, School of
Medicine in Katowice, Medical University of Silesia in Katowice
Department of Radiology and Nuclear Medicine, School of Medicine in Katowice, Medical
University of Silesia in Katowice

2. Glioblastoma multiforme
(GBM)
 is the most common and most malignant primary
brain tumor in adults worldwide (25%) despite
the progress in diagnosis an treatment in
oncology. GBM develops slowly, symptoms vary
depending on its location in the central nervous
system.

3. Aim of the study
 Presentation of the diagnostic path for
glioblastoma patient without collateral
diseases.

4. Case report
 A 55- year- old woman had a first
syncope incident during her holidays
abroad.
 She was generally in good health, never
smoked and without other serious
diseases in the past.

5.  Computer Tomography (CT) of the
chest, abdomen and mammography has
not revealed any suspect lesion.

6.  Magnetic resonance imaging (MRI) of the
head showed a high signal lesion(T1, DWI)
with intensive edema in the left frontal lobe

8.  Further diagnosis was continued in Poland
where it confirmed the presence of the
tumor in the left frontal lobe of the brain.

9. Before the operation- the control examination
was performed again.

10.  The tumor was resected via temporal
craniotomy a month after diagnosis. A
biopsy revealed diagnosis of glioblastoma
multiforme (IV).

11. After the operation

13.  In November 2016 after the biopsy, the
patient received chemotherapy with
Temodal (120 mg/day) and radiotherapy
(60 Gy, 30 times). Control MRI has not
shown new metastases.

14. MR scans- comparison.
August 2016
March 2017

16. Conlusions
 Glioblastoma multiforme remains an important
cause of morbidity and mortality from intracranial
tumors. The overall prognosis depends on the
time of imaging and surgery. However
interdisciplinary therapy can significantly prolong
postoperative survival.

17. Thank you for
your attention 