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CELL DEATH – APOPTOSIS
Presented by
Anil B. –18/MBT/003
Azad Kumar -18/MBT/005
Shivangi Asthana – 18/MBT/022
Sachin Kumar-18/MBT/025
CELL DEATH-
 Cell death is an important process in the body as it promotes the removal of unwanted cells.
 But why a cell should die ?
because
a. To allow body structures to grow and develop correctly.
b. To remove body structures that are no longer required.
c. To regulate the sizes of cell populations in adult bodies cell proliferation must be balanced with cell
death.
d. To kill cells that have been infected by pathogens.
e. To prevent the survival of cells with damaged DNA (these have the potential to become cancerous).
f. To prevent cells from surviving in environments where they should not be present.
etc.
The two forms of cell death
 Apoptosis: programmed cell death(cell death by suicide )
 Necrosis: uncontrolled cell death (cell death by injury)
TYPES OF APOPTOSIS
Broadly of two types
 Caspase independent (less common)
 Caspase dependent(more common)
 Then the more common 2 caspase dependent pathways are mainly divided into
two types –
1. Intrinsic Pathway
2. Extrinsic Pathway
PROTEINS AND SOME OTHER FACTORS INVOLVED IN APOPTOSIS
INTRINSIC PATHWAY OF APOPTOSIS
EXTRINSIC PATHWAY OF APOPTOSIS
REGULATION OF APOPTOSIS
CONCLUSION
THANK YOU

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Apoptosis.

  • 1. CELL DEATH – APOPTOSIS Presented by Anil B. –18/MBT/003 Azad Kumar -18/MBT/005 Shivangi Asthana – 18/MBT/022 Sachin Kumar-18/MBT/025
  • 2. CELL DEATH-  Cell death is an important process in the body as it promotes the removal of unwanted cells.  But why a cell should die ? because a. To allow body structures to grow and develop correctly. b. To remove body structures that are no longer required. c. To regulate the sizes of cell populations in adult bodies cell proliferation must be balanced with cell death. d. To kill cells that have been infected by pathogens. e. To prevent the survival of cells with damaged DNA (these have the potential to become cancerous). f. To prevent cells from surviving in environments where they should not be present. etc.
  • 3.
  • 4. The two forms of cell death  Apoptosis: programmed cell death(cell death by suicide )  Necrosis: uncontrolled cell death (cell death by injury)
  • 5. TYPES OF APOPTOSIS Broadly of two types  Caspase independent (less common)  Caspase dependent(more common)  Then the more common 2 caspase dependent pathways are mainly divided into two types – 1. Intrinsic Pathway 2. Extrinsic Pathway
  • 6. PROTEINS AND SOME OTHER FACTORS INVOLVED IN APOPTOSIS