Critical damage to cells can result in various forms of cell death, including necrosis, apoptosis, and immune-mediated cell death. Necrosis is the premature death of cells in living tissue due to factors like hypoxia, toxins, or trauma. It is characterized by cellular swelling and membrane breakdown. Apoptosis is a programmed form of cell suicide initiated by damage signals. The cell shrinks and fragments into apoptotic bodies that are phagocytosed. Immune-mediated cell death involves immune cells or complement killing damaged cells through phagocytosis or membrane attack. Necrosis of organs occurs when critical damage stops blood flow, leading to coagulative or liquefactive necrosis of all organ components. Outcomes include organization, inc