This document outlines Jimmy W. Smith's presentation on ILRI's future role in the emerging global context. It discusses key global challenges like feeding the world, climate change, and globalization that ILRI should address. Specifically over the next 5-10 years, ILRI should focus on improving smallholder livelihoods and market access, developing climate-smart livestock systems, and applying a One Health approach to advance animal, human and environmental health. ILRI also needs to strengthen its research programs within the CGIAR, leverage partnerships, and secure stable long-term funding to deliver solutions at scale.