This document discusses various methods of X-ray examination including direct analogue techniques using radiographic film or fluorescent screens, indirect analogue techniques using image intensifiers, and digital techniques. It also describes the components and functioning of X-ray machines, generation of X-rays, computed tomography which uses thin slices and rotation of the tube and detectors, and the use of contrast media to enhance visualization of organs and tissues.
I have include all the contain about mammography like introduction,principle,anatomy,general views ,mammography physics (x-ray tube, housing,filter ,collimator and generator) and different advance technology about mammography.
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Computed tomography (CT scan) is a medical imaging procedure that uses computer-processed X-rays to produce tomographic images or 'slices' of specific areas of the body. These cross-sectional images are used for diagnostic and therapeutic purposes in various medical disciplines.
X-ray imaging is still one of the most important diagnostic methods used in medicine. It provides mainly morphological (anatomical) information - but may also provide some physiological (functional) information.
I have include all the contain about mammography like introduction,principle,anatomy,general views ,mammography physics (x-ray tube, housing,filter ,collimator and generator) and different advance technology about mammography.
Hope it will help your queries.
Thank you....!!
Computed tomography (CT scan) is a medical imaging procedure that uses computer-processed X-rays to produce tomographic images or 'slices' of specific areas of the body. These cross-sectional images are used for diagnostic and therapeutic purposes in various medical disciplines.
X-ray imaging is still one of the most important diagnostic methods used in medicine. It provides mainly morphological (anatomical) information - but may also provide some physiological (functional) information.
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
1. X-Ray methods ofX-Ray methods of
examination.examination.
Bases of X-Ray semioticsBases of X-Ray semiotics
of pathology of differentof pathology of different
organs and systems.organs and systems.
2. 4 modalities (or 4 groups of methods) of modern4 modalities (or 4 groups of methods) of modern
Diagnostic imaging (Radiology):Diagnostic imaging (Radiology):
-- X-ray examinationX-ray examination;;
-- Nuclear medicine imagingNuclear medicine imaging;;
- Di- Diagnosticagnostic ultrasoundultrasound;;
- Magnetic resonance imaging- Magnetic resonance imaging ((MRI)MRI)..
X-ray and radionuclide examinations useX-ray and radionuclide examinations use ionizing radiationionizing radiation
Biological effect isBiological effect is tissue ionization.tissue ionization.
3. X-ray examination methods:X-ray examination methods:
- radiography,- radiography,
- fluoroscopy,- fluoroscopy,
- fluorography,- fluorography,
- tomography,- tomography,
- computed tomography.- computed tomography.
AllAll X-ray examinations are based on the detection ofX-ray examinations are based on the detection of
radiation passed through the patient (transmittedradiation passed through the patient (transmitted
radiation).radiation).
4. Technology of forming of x-ray images
Includes three components:
1 - radiant ( X-ray tube)
2 - object research
3 - perceiving device (detector) on which we get the visual
shadow image of the area that inspects
1
2
3
6. X-RAY MACHINE
1 - X-ray tube on a stand. 2 - High-voltage transformer, rectifiers
to change the AC current to DC, and a filament supply to control
the temperature of the filament (100-150 Kv applied across the
tube). 3 - Table for patient. 4 - control stand (in other room). 5 -
perceiving device :
- X-ray film.
- Quasi-conductor selenium plates
- Fluorescent screen.
-Electronically-optical
representation amplifier.
- Dosimeter detector.
1
5
3
2, 4
AC- alternate current
DC- direct current
7. X-rays are generated byX-rays are generated by X-ray tubeX-ray tube (( generatorgenerator of radiation).of radiation).
8. X-ray tube has a cathode, which emits electrons intoX-ray tube has a cathode, which emits electrons into
the vacuum and an anode to collect the electrons, thusthe vacuum and an anode to collect the electrons, thus
establishing a flow of electrical current, known as theestablishing a flow of electrical current, known as the
beam, through the tube.beam, through the tube.
A high voltage power source, for example 30 to 150A high voltage power source, for example 30 to 150
kilovolts (kV), is connected across cathode and anodekilovolts (kV), is connected across cathode and anode
to accelerate the electrons.to accelerate the electrons.
The X-ray spectrum depends on the anode materialThe X-ray spectrum depends on the anode material
and the accelerating voltage.and the accelerating voltage.
9. Electrons from the cathode collide with the anodeElectrons from the cathode collide with the anode
material, usually tungsten, molybdenum or copper,material, usually tungsten, molybdenum or copper,
and accelerate other electrons, ions and nuclei withinand accelerate other electrons, ions and nuclei within
the anode material.the anode material.
About 1% of the energy generated is emitted/radiated,About 1% of the energy generated is emitted/radiated,
usually perpendicular to the path of the electronusually perpendicular to the path of the electron
beam, as X-rays. The rest of the energy is released asbeam, as X-rays. The rest of the energy is released as
heat.heat.
10. Over time, tungsten will be deposited from the targetOver time, tungsten will be deposited from the target
onto the interior surface of the tube, including theonto the interior surface of the tube, including the
glass surface.glass surface.
This will slowly darken the tube and was thought toThis will slowly darken the tube and was thought to
degrade the quality of the X-ray beam.degrade the quality of the X-ray beam.
As time goes on, the tube becomes unstable even atAs time goes on, the tube becomes unstable even at
lower voltages, and must be replaced.lower voltages, and must be replaced.
12. NB!NB! Different tissues provide different degrees ofDifferent tissues provide different degrees of X-X-
ray attenuation.ray attenuation. Attenuation is aAttenuation is a loss of X-ray energyloss of X-ray energy..
Different tissues allow the transmission of differentDifferent tissues allow the transmission of different
amounts of X-ray. X-ray imaging is theamounts of X-ray. X-ray imaging is the imaging ofimaging of
shadows.shadows. X-rays penetrate tissues and are detected onX-rays penetrate tissues and are detected on
the other side of the patient by different detectors.the other side of the patient by different detectors.
Main groups of X-ray techniques:Main groups of X-ray techniques:
I)I) direct analogue techniques,direct analogue techniques,
2)2) indirect analogue techniques,indirect analogue techniques,
3)3) digital techniques.digital techniques.
13. Direct analogue techniques:
The final X-ray image is created directly on detector.
Detector: radiographic film or fluorescent screen.
The radiographic film responds with
blackening, the fluorescent screen
by fluorescence.
Two main direct of analogue techniques:
direct radiography and direct fluoroscopy.
14. DDirect radiography:irect radiography: the X-rays, after having passed through thethe X-rays, after having passed through the
patient, create an image directly on a radiographicpatient, create an image directly on a radiographic filmfilm. A 3-. A 3-
dimensional object is projected into a 2-dimensional image.dimensional object is projected into a 2-dimensional image.
ShadowsShadows of different organs areof different organs are summatedsummated on film. The imageson film. The images
only become visible after treatment with a developer. The image isonly become visible after treatment with a developer. The image is
negativenegative: the shadows of heart and bones are visualized as white or: the shadows of heart and bones are visualized as white or
light (so-calledlight (so-called opacityopacity), because they efficiently stops), because they efficiently stops
X-rays. Soft tissues are seen in grey tones andX-rays. Soft tissues are seen in grey tones and
gas is seen as black (so-calledgas is seen as black (so-called lucencylucency).).
15. DDirect fluoroscopyirect fluoroscopy (screening): the transmitted X-ray beam fall on(screening): the transmitted X-ray beam fall on
a fluorescent screena fluorescent screen, resulting in a, resulting in a dynamicdynamic projection light image.projection light image.
The image isThe image is positivepositive. The shadows of bones and heart are black. The shadows of bones and heart are black
((real opacityreal opacity), and gas is seen as white or light (), and gas is seen as white or light (real lucencyreal lucency).).
NB!NB! The image can be observed directly by the radiologist onThe image can be observed directly by the radiologist on
screen!screen!
Indirect fluoroscopyIndirect fluoroscopy employs X-ray image intensifier and TV-employs X-ray image intensifier and TV-
technique. Primary projection image is created on a fluorescenttechnique. Primary projection image is created on a fluorescent
screen, but screen image is not observed directly. The screen isscreen, but screen image is not observed directly. The screen is
part of anpart of an X-ray image intensifierX-ray image intensifier that enhances the brightness ofthat enhances the brightness of
the primary image. The intensified image may be recorded viathe primary image. The intensified image may be recorded via
lenses by a TV camera and shown on a monitor. The image islenses by a TV camera and shown on a monitor. The image is
positivepositive..
16. The image on fluorescent screen may also be reflected byThe image on fluorescent screen may also be reflected by
a mirror to a small-film still camera. Filming with this cameraa mirror to a small-film still camera. Filming with this camera
isis fluorographyfluorography (spot filming).(spot filming).
NB!NB! Sizes of fluorograms areSizes of fluorograms are
7x7 or 10x10 sm.7x7 or 10x10 sm.
17. TomographyTomography (conventional tomography):(conventional tomography):
- provides "- provides "sectionalsectional" images;" images;
- is based on- is based on movementmovement of X-ray tube andof X-ray tube and
film in such a way thatfilm in such a way that only a thin planeonly a thin plane throughthrough
the patient, parallel to the film, isthe patient, parallel to the film, is imaged sharplyimaged sharply..
Structures located in other planes (closer or more distant toStructures located in other planes (closer or more distant to
the film) are blurred due to dynamic unsharpness.the film) are blurred due to dynamic unsharpness.
18. Digital X-Ray techniques:Digital X-Ray techniques:
1.1. Digital radiography:Digital radiography:
exposure to X-rays special imaging plates retain a latentexposure to X-rays special imaging plates retain a latent
image of stored energy scanning the imaging plate with aimage of stored energy scanning the imaging plate with a
laser beam releasing energy as light or luminescencelaser beam releasing energy as light or luminescence
(the light intensity is proportional to the absorbed dose of X-(the light intensity is proportional to the absorbed dose of X-
ray photons) recording the emitted light by a photoray photons) recording the emitted light by a photo
detector as analogue signals digitizing the signalsdetector as analogue signals digitizing the signals
image in a grey scale format on a monitor (may beimage in a grey scale format on a monitor (may be
hardcopied by a laser printer).hardcopied by a laser printer).
2.2. Digital fluoroscopy/ digital fluorographyDigital fluoroscopy/ digital fluorography ::
digitizing the analogue video signal from the TV camera indigitizing the analogue video signal from the TV camera in
an X-ray image-intensifier-television system image onan X-ray image-intensifier-television system image on
TV monitor (TV monitor (digital fluoroscopy)digital fluoroscopy) image photographedimage photographed
by a small-film camera (by a small-film camera (digital fluorographydigital fluorography).).
The primary image at digital techniques isThe primary image at digital techniques is positive!positive!
19. Computed Tomography:Computed Tomography:
onlyonly thin tissue slicesthin tissue slices are exposed to X-rays!are exposed to X-rays!
The tube and detectorsThe tube and detectors rotate togetherrotate together around thearound the
patient.patient.
Thin beam of X-rays, perpendicular to the long axis ofThin beam of X-rays, perpendicular to the long axis of
the body, emitted from the tube transmitted thethe body, emitted from the tube transmitted the
beam of X-rays through the patient detection bybeam of X-rays through the patient detection by
scintillationscintillation oror ionization detectorsionization detectors..
CT detectors are at least 100 timesCT detectors are at least 100 times more sensitivemore sensitive thanthan
radiographic film!radiographic film!
20. Computed Tomography:Computed Tomography:
Advantages of CT:Advantages of CT:
- good contrast resolution;- good contrast resolution;
- sectional images of any part of the body;- sectional images of any part of the body;
21. Computed Tomography:Computed Tomography:
Advantages of CT:Advantages of CT:
-- measurementmeasurement of tissue attenuation:of tissue attenuation:
linear scale ranges from -1,000 to 3,000 of Hounsfield unit (HU).linear scale ranges from -1,000 to 3,000 of Hounsfield unit (HU).
22. Computed Tomography:Computed Tomography:
Advantages of CT:Advantages of CT:
NB!NB! A recently introduced spiral and multislice CT haveA recently introduced spiral and multislice CT have
increased the efficiency of CT scanningincreased the efficiency of CT scanning
very high quality three-dimensional reconstructions.very high quality three-dimensional reconstructions.
23. CContrast mediaontrast media for X-Ray examinationfor X-Ray examination
Purpose:Purpose: visualization of empty and somevisualization of empty and some
parenchymal organs in conventional radiologyparenchymal organs in conventional radiology
and CT.and CT.
Negative contrast mediaNegative contrast media (air and other gases):(air and other gases):
attenuate X-rays less than the soft tissuesattenuate X-rays less than the soft tissues
and are seen asand are seen as lucencylucency..
Positive contrast media:Positive contrast media:
attenuate X-rays more than the soft tissuesattenuate X-rays more than the soft tissues
and are seen asand are seen as opacityopacity..
Positive contrast media:Positive contrast media:
-- water solublewater soluble (water solutions of organic(water solutions of organic
compounds with iodine),compounds with iodine),
-- water insolublewater insoluble (barium sulphate).(barium sulphate).
24. Water soluble contrast mediaWater soluble contrast media are used for:are used for:
- urography,urography,
- cholangiography,cholangiography,
- angiography and angiocardiography;angiography and angiocardiography;
- bronchography;bronchography;
- hysterosalpingography;hysterosalpingography;
- enhancing attenuation differences at CT.enhancing attenuation differences at CT.
25. Water insoluble contrast mediaWater insoluble contrast media are used for :are used for :
- conventional X-ray examination ofconventional X-ray examination of esophagus,esophagus,
stomach and duodenumstomach and duodenum (performed with single-(performed with single-
or double-contrast barium meal; for the double-or double-contrast barium meal; for the double-
contrast study combination barium-gas is used);contrast study combination barium-gas is used);
- conventional X-ray examination ofconventional X-ray examination of large bowellarge bowel
(performed with the single- or double-contrast(performed with the single- or double-contrast
barium enema –barium enema – irrigographyirrigography).).
NB!NB! As a rule, so-called barium studiesAs a rule, so-called barium studies
are fluoroscopy, during it radiographyare fluoroscopy, during it radiography
usually is performed.usually is performed.