The document provides an overview of x-ray physics, including a history of x-rays, the electromagnetic spectrum, properties of x-rays, components of an x-ray tube, and interactions between x-rays and matter. It describes how x-rays are produced via thermionic emission in an x-ray tube, where high-speed electrons generated at the cathode strike the tungsten anode, producing bremsstrahlung and characteristic radiation. It also summarizes the photoelectric effect and Compton scattering that can occur when x-rays interact with matter.
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
Interactions of X-ray & matter & Attenuation - Dr. Sayak DattaSayakDatta
Slideshow on Radio-physics covering different interactions between X-ray and matter along with Attenuation. It includes Photo-electric effect, Compton scatter, Coherent scatter, Attenuation of Monochromatic & Polychromatic radiation, Diagnostic Xray applications, Scatter radiations.
X- Ray physics- X-Ray Tube, Transformer, Generator and Rectifiers by kajalsra...DrKajalLimbad
X-Ray physics including x-ray tube, transformer, generator, and rectifiers. physics made an easy
Note: this ppt has many animations that may not be appreciated over here. Request original ppt at kajalsradiology@gmail.com
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
4. Nature of X-rays
✤ X-rays are classified as Electromagnetic radiation- wavelike like fluctuations
of electric & magnetic fields set up in space by oscillating electrons.
✤ Electromagnetic radiation consists of energy in small pockets called photons.
✤ Speed of X-rays = constant = Speed of light = 3 x 108 m/s
✤ The wavelength of X-rays are extremely short;in ordinary radiography,their
useful range extends from about 0.1Ao-0.5Ao
✤ The ultrashort wavelengths are associated with enormous frequencies from 3 x
1019 to 6 x 1018 Hertz.
6. Properties of X-rays
✤ X-rays travel in straight lines.
✤ X-rays are electrically neutral.
✤ X-rays are polyenergetic and heterogeneous.(useful energy range in
conventional radiography is about 20-120kVp).
✤ X-rays travel at the speed of light-electromagnetic radiation.
✤ X-rays are highly penetrating,invisible rays.
✤ X-rays cannot be deflected by electric or magnetic field.
7. Properties of X-rays
✤ X-rays cannot be focused by lens.
✤ Photographic film is blackened by X-rays.
✤ Fluorescent materials glow when X-rays are directed at them.[making possible
their use in fluoroscopy].
✤ Produce chemical and biologic changes by ionisation and excitation.
✤ Liberate minute amounts of energies while passing through matter.
✤ X-rays interact with matter produce photoelectric and compton effect.
8. The X-ray tube
✤ Hot cathode - diode tube based on edison effect.
9.
10.
11. X-ray tube components
✤ Hot Filament : supplied by low voltage heating current ,serves as cathode(negative
electrode) releases electrons when heated.
✤ Focusing cup : focuses electrons on target.
✤ Target : tungsten target serves as anode or positive electrode.
✤ Copper stem : helps remove heat from target in stationary aode tubes.(copper is a better
conductor of heat).
✤ Glass envelope/tube : from which the air has been evacuated as completely as possible.
✤ Degassing : process of removing air from glass & metal parts by prolonged baking before
tube is sealed.
12. Why Vaccum???
Two reasons :
✤ To prevent collision of the high speed electrons with gas molecules,which
would cause significant slowing of electrons.
✤ To prevent Oxidation & burning out of filament.
14. Two ways by which X-rays can be generated
✤ Whenever fast moving electrons undergo rapid deceleration.
✤ Electrons drop from an outer shell to a hole in an inner atomic shell.
15. What does X-ray tube do?
✤ Obtains free electrons———>Speeds them up ——->Finally stops them to
generate X-rays.
16. Steps in X-ray Production
✤ Obtaining free electrons by heating filament with low voltage circuit.
✤ Applying high potential difference across electrodes causing electrons to
race towards Anode.
✤ Focusing electrons on the focal spot of anode by focusing cup.
✤ Stopping the high speed electrons in target.
17. Separation of Electrons:
✤ Filament current supplying the filament causes it to become glowing hot or
Incandescent,with resulting separation of some of its outer orbital
electrons.
✤ Separated electrons escaping from the filament,form a cloud or space
charge nearby.
The electrons liberated in this manner are called THERMIONS & the
process of their liberation through the heating of a conductor by an
electric current is called THERMIONIC EMISSION.
18. Production of High speed electrons
✤ A high Potential difference is applied across the tube which gives the filament a
very high negative charge (cathode) & the target an equally high positive
charge(anode).
✤ The resulting strong electric field causes the space charge electrons to rush at
an extremely high speed through the tube from cathode to anode.
✤ This electron stream is expressed in milliAmperes,while total charge
transferred in the process is in mAs.
The speed of the electrons at 80kVp is about 80 percent of the speed of
light !
19. Focusing of the electrons
✤ The metal focusing cup around the cathode helps focus the electrons on the
focal spot of the anode by forming the narrow electron beam,narrower the
electron beam smaller the focal spot and sharper the xray images!
20. Stopping of the High Speed Electrons in Target
✤ When the fast electrons enter target of the x-ray tube,their kinetic energy
changes to Heat,light & X-rays.
✤ X-ray tube efficiency is such that at 80kVp only about 0.6 percent of this
energy is converted to x rays while the remaining 99.4 percent appears as
heat.
21. Electron Interactions with Target Atoms
1)Brems Radiation
✤ Upon approaching the strongly positive nuclear field of a target
atom,the negatively charged high speed electron is deviated
from its initial path because of the attraction between opposite
charges resulting in slow down or deceleration of
electrons,thereby losing some of its kinetic energy.
✤ The lost kinetic energy is radiated as an X-ray of equivalent
energy.a/k/a Brems radiation or braking radiation or
bremsstrahlung radiation.
✤ The deceleration of electrons depends also on atomic number
of target,thus targets of higher atomic number are more efficient
producers of Brems radiation.
23. ✤ An electron with a sufficient minimum kinetic energy may interact with an
inner orbital electron of a target atom,ejecting it from its orbit creating a
hole .this makes atom unstable being ionized & in excited state.
✤ This space or hole is filled by electron transition from one of the outer shells
emitting the energy while transition which is emitted as characteristic x ray
because its energy is unique to target element & the involved shell.
24. Summary of Radiation
✤ Bremsstrahlung radiation :
✤ White,Polyenergetic radiation with a continuous range of energies & wavelengths due to
deceleration of electrons by strongly positive electric fields of nuclei in target atoms.
✤ Constitutes about 90 percent of emitted x rays when 80 - 100 kV is applied to the tube.
✤ Characteristic radiation :
✤ Consists of limited,discrete energies & wavelengths.
✤ Constitutes about 10 percent of emitted x rays when 80 - 100 kV is applied to the tube.
No characteristic radiation is produced at tube potentials less than 60 kV with a tungsten
target.
25. Efficiency of X-ray Production
✤ %efficiency = k x Z x kVp
Where, k = constant = 10-4
Z = atomic number of the target
kVp = peak kilovoltage.
Eg, At 80kVp with tungsten target (z=74)
Efficiency = 0.6% meaning of the total kinetic energy of the electron stream,only
about 0.6% appears as x rays and the remaining 99.4% as the heat in the anode when
applied potential is 80kVp.
26. Target Material - Tungsten
✤ Two things to remember while selecting target material :
✤ It must have a very high melting point to withstand the extremely high
temperature.
✤ It must have a high atomic number because
✤ The resulting characteristic radiation will be of high energy and more penetrating.
✤ There is increased production of Brems radiation.
Tungsten - Melting point 33700c ; Atomic Number = 74 satisfies both requirements.
27. ✤ Target Material in rotating anode radiographic tubes : Rhenium &
Tungsten coated on a Molybdenum-tungsten disc
✤ Mammographic tubes use Molybdenum (Z=42) targets to produce low
energy X-rays.
29. ✤ On passing through a body of Matter,an X-ray beam undergoes
attenuation,that is progressive decrease in initial number of photons.
✤ Attenuation is due to two processes
✤ Absorption of some of the photons.
✤ Emission of scattered & secondary radiation.
✤ Loss of beam intensity due to inverse square law.
Scattered radiation - x ray photons that have undergone a change in
direction after interacting with atoms.
Secondary radiation - Characteristic radiation emitted by atoms after having
absorbed x ray photons.
30. ✤ Four kinds of interactions may occur between the photons and atoms in
their path,depending on the atomic number of the atoms and the energy of
the photons :
1. Photoelectric Interaction.
2. Coherent or Classical scattering.
3. Compton interaction with modified scattering.
4. Pair production.
31. Binding energy:
✤ The energy required to remove an electron from a
particular shell and beyond the range of the nuclear
positive electrostatic field is called the binding energy of
that shell.
✤ The shells are at a progressively higher energy levels the
farther they are located from the nucleus.
✤ Inner shell electrons are called as bound electrons
owing to high energy needed to remove electrons
✤ Almost no energy is required to liberate an electron from
outer shells,so they are called free or valence
electrons.
More the atomic number more the number of protons
more the binding energy.
32. Photoelectric Interaction (Photoelectric Effect)
✤ This type of interaction is most likely to occur when the energy hv of the
incident x-ray photon is slightly greater than the binding energy of the
electrons in one of the inner shells such as K or L.
✤ The incident photon gives up all of its energy to the atom (photon is truly
absorbed and disappears during the interaction).
33.
34. ✤ The incident photon gives all of its energy to the atom——>Immediately the
atom responds by ejecting an electron,usually from K or L shell leaving the
hole in that shell——>Now the atom is Ionised positively & in an excited
state.
✤ So the energy of incident photon ultimately went to-
1. Free the electron fron its shell &
2. Set it in motion as a photoelectron,which ionizes atoms nearby &
releases secondary electrons.
35. ✤ In summary, the energy of the incoming photon in the photoelectric interaction involving K shell
has the following fate :
1. Photon enters the atom and completely disappears.
2. A K shell electron is ejected,leaving a hole.
3. Atom has excess energy-excited state.
4. A part of photons energy was used to liberate electron and rest to it kinetic energy; ejected
electron is a photoelectron,which releases secondaro electrons by ionising other atoms.
5. Hole in the k shell is filled by electron transition from a shell farther out,accompanied by
emission of a characteristic x ray photon.
6. Holes in successive shells are filled by electron transitions from shells still farther
accompanied by a corresponding characteristic photon;this sequence is a cascade
7. Sum of energies of all the characteristic photons equals binding energy of shell from
whichthe photoelectron originated,in this case the K shell.
37. ✤ If a very low energy x-ray photon interacts with a firmly bound orbital
electrons,it may setthe electron into vibration producing an electromagnetic
wave identical in energy to that of incident photon,but differing in direction.
✤ Scattering without undergoing any change in wavelength,frequency or
energy.
39. ✤ If an incident photon of sufficient energy encounters a loosely bound,outer
shell electron it may dislodge the electron & proceed in a diffraction
direction.
✤ The dislodged electron is called a compton or recoil electron.
40. ✤ As energy of incident photon increases probability of occurence of compton
interaction decreases but, at the same time the scattered photons have
more energy & tend to be scattered more and more in forward
direction,increasing the likelihood of their passing completely through the
body amd reaching the film constituting scattered radiation which in
radiography impairs image contrastby an overall fogging effect.
42. Anode
✤ Two main types of Anodes
✤ Stationary Anode - used in dentistry. Tungsten in a block of copper.
✤ Rotating Anode- Molybdenum disc coated with a tungsten - rhenium alloy to
serve as the focal track target.
✤ Rhenium diminishes roughening of the focal track with use,thereby
ensuring high x-ray output or emmissivity.
✤ For heavy duty tubes, a layer of graphite under the moly disc reduces the
weight of the large anodeand hastens the dissipation of heat.
44. ✤ The walls of darkroom should contain lead atleast 1.6mm thick.
✤ Radioactive materials should be located as remotely as possible
✤ Windows should be avoided.
✤ Should be readily accessible to plumbing and electrical services.
LOCATION
45.
46. Building Essentials
✤ Passboxes are built into walls at appropriate location,they have two light tight and x-ray
proof doors that are so interlocked that both can’t be opened at same time.
✤ The cassettes after radiographic exposure are placed in passbox through the outside
door by the x-ray technician then removed through the inside door by the dark room
technician.
✤ Dark room walls should be covered with chemical resistant material made of special
paint,varnish or lacquer.
✤ Floors are covered with chemical resistant and stain proof material such as asphalt tile.
✤ Floors should be non skiddy made of porcelain or clay tile.
47. Entrances
✤ Single door - it must be light tight by weatherstripping,it is the simplest type.
✤ It should have an inside lock to prevent opening while films are being
processed.
✤ Small hall with two electrically interlocked doors
✤ One door cannot be opened until other is completely closed thereby
preventing light.
✤ There is separate door for emergency
48.
49. ✤ Maze or labyrinth entrance
✤ One has to do a complete turn going through three doors it serves as a light trap.
✤ It requires no doors.
✤ Walls may be painted black
✤ Rarely used now-a-days.
✤ Two way revolving darkroom door
✤ Outer cylindrical chamber built into the wall,has two openings one into the dark room and
other into the light room
✤ The inner chamber has one door which is suspended at its top by a central bearing,can
easily be rotated by means of a hand rail until its opening coincides with either of the
openings in outer chamber.
✤ Entire unit is completely light proof and takes up very little space.
50.
51.
52. ✤ Ventilation- AC / Exhaust may provide adequate ventilation.
✤ Lighting - three types if illumination
✤ 1) safelight 2) general illumination 3) radioghic illumination.
53. ✤ Safelight -
✤ Source of light which will not fog films and provide adequate illumination
✤ Safelight lamps with adequate filters are used ,working distance not less
than 1 meter.
✤ General illumination :
✤ Source of overhead illumination for general purpose like
cleaning,changing solution etc.
✤ Radiographic Illumination :
✤ Fluorescent illuminator for viewing wet radiographs mounted over
washing compartment.
55. ✤ An ordinary radiographic film emulsion contains silver halides in the form of
minute crystals that are invisible to naked eye consisting of mainly silver
bromide and small amount of silver iodide to enhance sensitivity.
56.
57. Gurney-mott hypothesis of latent image
formation
✤ A photon entering a sensitized silver halide crystal may interact with a bromine
ion,liberating a loosely bound valence electron and leaving a neutral bromine atom.
✤ As the free electron drifts through the lattice,it may be trapped by a sensitivity speck
to which it imparts a negative charge.
✤ A migrant positive silver ion,attracted to the now negatively charged sensitivity
speck picks up the electron and becomes a neutral silver atom adhering to the
speck.this process is called as nucleation.
✤ The silver atoms deposited on sensitivity speck are too few in number to be
visible,so they constitute the latent image.
58.
59. ✤ When the latent image is acted upon by reducing agents known as
devolopers,the process initiated by photon action is greatly speeded up;the
sensitivity speck serves as a devolopment centre for the entire crystal.
✤ The speck rapidly traps electrons from the reducing agents and attracts
more silver ions which become reduced to silver atoms and grow into
thread-like or in some film emulsions,tabular clusters of metallic silver.thus,
the dark areas consist of metallic silver in a very fine state of subdivision.
60. ✤ During the devolopment bromine ions diffuse out of the devoloped crystals
and into the solution.this in addition to the gradual exhaustion of the
reducing agents,eventually cause deterioration of the developer to the point
where it must be discarded.
✤ The unexopsed and underdeveloped silver halides are eliminated from the
emulsion by immersion in a fixing agent,ammonium thiosulfate,a process
knows as fixation. As a result,the areas from which the silver halides have
been removed become clear,while the black areas remain black since
metallic silver is not dissolved by fixing agent in the ordinary course of
processing.
✤ Prolonged immersion in fixing solution causes bleaching of the image.
61. ✤ The amount of blackening of particular area of a radiograph depends on the
amount of radiation it has received.this is the radiation that has passed
through the various thicknesses,types and densities of the tissue interposed
between the tube and the film and is called remnant or exit radiation.it
forms the aerial image.
63. ✤ Devolopment :
✤ Development in a solution containing an organic reducing agent, such as
hydroquinone and metol, to convert ionic silver to metallic silver.
✤ An alkali, sodium hydroxide, serves as an accelerator; and a restrainer
prevents chemical fogging, finally, an antioxidant, sodium sulfite, slows
oxidation of the devoloper by air.
64. ✤ Rinsing :
✤ Rinsing in a solution of acetic acid(vinegar) to neutralise the alkali carried
over from the devoloper, hereby stopping devolopment.
65. ✤ Fixation :
✤ In a solution of hypo to remove the unexposed, underdeveloped silver
halides and so preserve the image. A hardner alum, toughens the
emulsion, actually tanning it.
66. ✤ Fixer Neutralisation :
✤ Done in a special solution to remove any residual fixer,to help prevent
deterioration and discoloration of image.
67. ✤ Washing :
✤ Done by immersion of the films in running water for a prescribed time to
remove effectively any residual chemicals.
68. ✤ Drying :
✤ In a special cabinet preferably with a source of forced heat.
The minimum time possible for the manual processing is about 40 mins.