Wound healing (cutaneous)
•Download as PPTX, PDF•
2 likes•100 views
Wound healing involves three overlapping phases: inflammatory, proliferative, and remodeling. In the inflammatory phase, fibrin and a provisional matrix form over the wound to prevent infection. In the proliferative phase, re-epithelialization occurs to regrow skin cells over the wound. Granulation tissue forms below the wound as new blood vessels and extracellular matrix develop. Collagen is deposited and remodeled. Finally, in the remodeling phase, collagen is reorganized and cross-linked to increase wound strength as it matures over 6-12 months. Factors like age, nutrition, smoking, and infection can impact wound healing.
Report
Share
Report
Share
Recommended
Biomaterial science presentation
The document discusses skin repair and wound healing. It describes the three phases of wound healing as hemostasis, inflammation, and proliferation. It also discusses factors that affect healing, classifications of wound healing, and the use of wound dressings made from materials like alginate and chitosan to promote healing and prevent infection.
wound healing general concept
This document discusses wound healing and contains the following key points:
1. It describes the different types of wounds including surgical, contaminated, and fractures.
2. It outlines the stages of wound healing: hematoma formation, inflammation, granulation tissue formation, and maturation/remodeling.
3. It lists both local factors like moisture and ischemia and systemic factors like diabetes, smoking, and age that can affect the wound healing process.
Inflammation 9
The document discusses wound healing and fibrosis. It describes that wound healing occurs in three phases: inflammation, proliferation, and maturation. It also discusses primary and secondary wound healing. Primary healing involves wounds with opposed edges that heal with a thin scar, while secondary healing involves wounds with tissue loss that heal with more scarring and contracture. The document also discusses factors that influence wound healing and complications that can arise. It provides details on cutaneous wound healing and fracture healing processes. Finally, it discusses fibrosis, describing that it is excessive collagen deposition in tissue during repair. It notes the role of macrophages and TGF-beta in promoting fibrosis.
Wound healing [including healing after periodontal therapy]
The document discusses wound healing and periodontal wound healing in particular. It describes the processes of regeneration and repair. Regeneration involves renewal of tissues through growth of same tissue type, while repair involves replacement of tissues through scar formation. The molecular biology of wound healing is explained, including roles of fibrin clot, growth factors, matrix degradation and connective tissue formation. Healing by primary and secondary intention is also defined. Healing processes following various periodontal procedures like scaling, root planing, flap surgery and implant placement are outlined. Factors influencing wound healing and potential complications are briefly mentioned.
Repair of periodontal tissues
1. The document discusses the process of wound healing, which involves regeneration and repair through distinct phases - inflammatory, proliferative, and maturation.
2. During the inflammatory phase, platelets form clots to stop bleeding while macrophages and leukocytes remove debris. Growth factors are released to stimulate healing.
3. In the proliferative phase, new tissue is formed through granulation, angiogenesis, collagen deposition, epithelialization, and contraction.
4. Finally, in the maturation phase scar tissue is remodeled and strengthened over time through collagen remodeling.
Wound healing prosthodontics
The document discusses various aspects of wound healing, including definitions of regeneration, repair, and primary and secondary intention healing. It describes the process of regeneration as proliferation of parenchymal cells to restore original tissues, while repair involves proliferation of connective tissue elements and fibrosis. Primary intention healing occurs when a clean, surgically incised wound is approximated by sutures, resulting in re-epithelialization within 48 hours and scar formation over 4 weeks. Secondary intention healing applies to wounds with tissue defects that are left open to heal more slowly through granulation tissue formation and contraction over weeks.
Wound healing / dental crown & bridge courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Healing and repair
Healing occurs through regeneration or scar formation depending on the cell and injury type. Wound healing follows two main pathways: primary intention for clean surgical wounds where edges are approximated, or secondary intention for wounds with separated edges and more tissue death. The process involves inflammation, granulation tissue formation, re-epithelialization, wound contraction and ECM deposition. Several local and systemic factors can delay healing including infection, poor blood supply, drugs, and nutritional deficiencies.
Recommended
Biomaterial science presentation
The document discusses skin repair and wound healing. It describes the three phases of wound healing as hemostasis, inflammation, and proliferation. It also discusses factors that affect healing, classifications of wound healing, and the use of wound dressings made from materials like alginate and chitosan to promote healing and prevent infection.
wound healing general concept
This document discusses wound healing and contains the following key points:
1. It describes the different types of wounds including surgical, contaminated, and fractures.
2. It outlines the stages of wound healing: hematoma formation, inflammation, granulation tissue formation, and maturation/remodeling.
3. It lists both local factors like moisture and ischemia and systemic factors like diabetes, smoking, and age that can affect the wound healing process.
Inflammation 9
The document discusses wound healing and fibrosis. It describes that wound healing occurs in three phases: inflammation, proliferation, and maturation. It also discusses primary and secondary wound healing. Primary healing involves wounds with opposed edges that heal with a thin scar, while secondary healing involves wounds with tissue loss that heal with more scarring and contracture. The document also discusses factors that influence wound healing and complications that can arise. It provides details on cutaneous wound healing and fracture healing processes. Finally, it discusses fibrosis, describing that it is excessive collagen deposition in tissue during repair. It notes the role of macrophages and TGF-beta in promoting fibrosis.
Wound healing [including healing after periodontal therapy]
The document discusses wound healing and periodontal wound healing in particular. It describes the processes of regeneration and repair. Regeneration involves renewal of tissues through growth of same tissue type, while repair involves replacement of tissues through scar formation. The molecular biology of wound healing is explained, including roles of fibrin clot, growth factors, matrix degradation and connective tissue formation. Healing by primary and secondary intention is also defined. Healing processes following various periodontal procedures like scaling, root planing, flap surgery and implant placement are outlined. Factors influencing wound healing and potential complications are briefly mentioned.
Repair of periodontal tissues
1. The document discusses the process of wound healing, which involves regeneration and repair through distinct phases - inflammatory, proliferative, and maturation.
2. During the inflammatory phase, platelets form clots to stop bleeding while macrophages and leukocytes remove debris. Growth factors are released to stimulate healing.
3. In the proliferative phase, new tissue is formed through granulation, angiogenesis, collagen deposition, epithelialization, and contraction.
4. Finally, in the maturation phase scar tissue is remodeled and strengthened over time through collagen remodeling.
Wound healing prosthodontics
The document discusses various aspects of wound healing, including definitions of regeneration, repair, and primary and secondary intention healing. It describes the process of regeneration as proliferation of parenchymal cells to restore original tissues, while repair involves proliferation of connective tissue elements and fibrosis. Primary intention healing occurs when a clean, surgically incised wound is approximated by sutures, resulting in re-epithelialization within 48 hours and scar formation over 4 weeks. Secondary intention healing applies to wounds with tissue defects that are left open to heal more slowly through granulation tissue formation and contraction over weeks.
Wound healing / dental crown & bridge courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Healing and repair
Healing occurs through regeneration or scar formation depending on the cell and injury type. Wound healing follows two main pathways: primary intention for clean surgical wounds where edges are approximated, or secondary intention for wounds with separated edges and more tissue death. The process involves inflammation, granulation tissue formation, re-epithelialization, wound contraction and ECM deposition. Several local and systemic factors can delay healing including infection, poor blood supply, drugs, and nutritional deficiencies.
Wound healing
The document discusses the phases of wound healing:
1) Hemostasis and inflammation occurs within the first few days as the wound clots and immune cells clear debris.
2) Proliferation spans days 4-12 as new tissue is formed through fibroblast and endothelial cell proliferation and migration. Collagen and new blood vessels are deposited.
3) Maturation and remodeling can take months as the wound contracts and collagen is reorganized and remodeled, increasing strength of the healed tissue.
Wound healing ( adesiyakan)
trauma
wound healing
medical education
plastic surgery
surgery
African experience
Nigerian surgery
stages of wound healing
phases of wound healing
collagen storage disease
wound Healing/endodontic courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
wound healing/cosmetic dentistry courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Healing and repair by Dr. Kachinda wezi 2018
Wound healing is a complex process involving inflammation, tissue regeneration, and scar formation. It can occur through regeneration of parenchymal cells or through the formation of granulation tissue and scarring. The key steps are inflammation, proliferation of fibroblasts and blood vessels to form granulation tissue, collagen deposition, and remodeling. Healing occurs through primary intention in clean closed wounds and secondary intention in open wounds with tissue loss. Many factors like nutrition, infection, age, and medications can influence the healing process.
Cutaneous wound healing
Cutaneous wound healing occurs through first or second intention. Primary union (first intention) involves clean surgical incisions approximated by sutures, resulting in relatively thin scar formation. Secondary union (second intention) involves larger defects without sutures, resulting in formation of granulation tissue and more substantial scarring due to wound contraction. The stages of wound healing include formation of a blood clot, granulation tissue, re-epithelialization, collagen deposition, and scar formation.
Wound healings
The document discusses the three main phases of wound healing: inflammatory, proliferative, and remodeling. In the inflammatory phase, blood vessels constrict and immune cells are recruited to fight infection. The proliferative phase involves new tissue growth through granulation, collagen deposition, angiogenesis and epithelialization. Finally, the remodeling phase lasts for months as the scar matures and collagen is reorganized. Through these coordinated phases, the body works to close and resurface wounds.
Acromegaly 19.07.08
Wound healing involves four phases - haemostasis, inflammation, proliferation, and remodeling. In haemostasis, platelets form clots to stop bleeding. Inflammation brings immune cells to fight infection and remove debris. Proliferation involves new tissue growth through cells like fibroblasts, endothelial cells, and keratinocytes. Remodeling strengthens the wound over months through collagen remodeling. Nutrition, infection, diabetes and other systemic factors can impact wound healing. Occlusive dressings aid healing by keeping wounds moist and preventing infection.
WOUND HEALING AND ENDODONTICS
The document discusses various topics related to wound healing, including:
- The classification, types, and factors that affect wound healing.
- The two main processes in healing are regeneration (restoration of original tissues) and repair (fibrosis and scarring).
- Healing occurs through the stages of inflammation, clearance of debris, and ingrowth of granulation tissue.
- Specific examples discussed include healing of fractures, non-surgical root canals, excisional dentoalveolar wounds, replanted teeth, and dental implants.
- Complications like infection, delayed/non-union can occur if healing is disrupted.
Inflammatory Principles & Athletic Rehab
The document summarizes the inflammatory process and its phases:
1) The acute/early inflammatory phase involves vasodilation, increased permeability and edema, phagocytosis by immune cells to remove debris.
2) The proliferation phase involves tissue regeneration through re-epithelialization, angiogenesis and fibroplasia to form new scar tissue.
3) During the remodeling phase lasting up to a year, collagen is reorganized and strengthened to gradually restore function.
Healing and repair
1. Tissue repair involves regeneration of injured tissue or replacement by connective tissue scarring. It involves cell proliferation and interaction between cells and the extracellular matrix.
2. Tissues are divided into continuously dividing, stable, and permanent groups based on their ability to proliferate. Continuously dividing tissues like skin regenerate easily while permanent tissues like neurons cannot regenerate after injury.
3. Growth factors and the extracellular matrix play important roles in tissue repair by stimulating cell growth and movement. Repair occurs through regeneration in labile tissues and scarring in others when injury is too severe for regeneration.
Wound healing
Detailed presentation on wounds, classification, phases of healing and management for resident doctors, medical students and nurses
Wound healing
This document provides an overview of wound healing. It begins with definitions of regeneration, repair, and the two types of wound healing: primary intention and secondary intention. For regeneration and repair, it describes the molecular events of cell growth, proliferation, and extracellular matrix formation. It then covers the stages of primary and secondary wound healing in more detail. Specialized tissue healing like fractures is also summarized. Factors influencing wound healing and complications are listed. The document contains detailed information on the cellular and molecular processes involved in wound healing.
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...CLOVE Dental OMNI Hospitals Andhra Hospital
This document discusses wound healing and fracture healing processes. It describes the phases of wound healing including inflammation, granulation tissue formation, and wound contraction in primary and secondary healing. Factors influencing wound healing like infection, nutrition and diabetes are covered. Complications of healing such as hypertrophic scarring and keloid formation are mentioned. Commonly used wound healing materials like oxidized regenerated cellulose and Whitehead's varnish are briefly described. Fracture healing through procallus formation, osseous callus formation and remodeling is summarized.Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Wound healing in Dentis...
entist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Wound healing in dentistry.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
Subscribe our channel on youtube - Copy and paste this URL. https://www.youtube.com/channel/UC_gylEXTrjmEbbOTSXjuZ4Q/videos?view_as=public
Follow us on Slideshare.
Ug wound healing
basic concepts of tissue injury and healing process. emphasis placed on primary and secondary type of wound healing.
Tissue healing
Tissue healing involves regeneration and repair. Regeneration is the proliferation of original cells to restore tissues, while repair is the replacement of injured tissue with fibrous scar tissue. Some key points about tissue healing include:
- Regeneration occurs through growth factors stimulating cell proliferation and the regeneration of parenchymal cells.
- Repair involves the formation of granulation tissue from fibroblasts and new blood vessels, followed by wound contraction.
- Skin wound healing occurs primarily through regeneration, while fractures heal through formation of a callus during repair.
- Nerve and muscle tissues have limited regenerative abilities.
Wound healing
The document discusses the stages of wound healing including hemostasis, inflammation, proliferation, and remodeling, and the factors that influence wound healing such as wound type, patient health, and environmental conditions. It also covers abnormal wound healing which can result in hypertrophic or keloid scarring, and treatments for scarring including pressure therapy, steroid injections, and surgery.
Physiology of wound healing
Wound healing is a complex process involving four cell types that occurs in distinct phases: hemostasis, inflammation, proliferation, and maturation. Chronic wounds get stuck in the inflammation phase due to factors like increased cytokines, altered growth factors, and senescent cells. Tissue engineering techniques aim to promote healing by combining cells and biomaterials into functional tissues. One such technique uses autologous cancellous bone mixed with stem cells and allogeneic platelet gel growth factors to treat non-union bone fractures.
Pathways for cellular uptake of nanoparticles.pptx
PROVIDES.
1. Entry of nanoparticles into body.
2.Formation of protein corona.
3.Cellular uptake.
4.Endocutotic pathways..
a. Phagocytosis.
b. Clathrin mediated.
c. Caveolae mediated.
d. Pinocytosis.
5.Fate of Nanoparticle.
6.Effects.
7.conclusion
Macrophage phenotype
A brief introduction of macrophage phenotype including research timelines, the pathways and functional of M1 and M2 phenotype.
Gametogenesis, fertilization, implantation and 1st wk development
its a presentation of introduction of embryology, gametogenesis, fertilization, implantation and 1st wk of development.
More Related Content
What's hot
Wound healing
The document discusses the phases of wound healing:
1) Hemostasis and inflammation occurs within the first few days as the wound clots and immune cells clear debris.
2) Proliferation spans days 4-12 as new tissue is formed through fibroblast and endothelial cell proliferation and migration. Collagen and new blood vessels are deposited.
3) Maturation and remodeling can take months as the wound contracts and collagen is reorganized and remodeled, increasing strength of the healed tissue.
Wound healing ( adesiyakan)
trauma
wound healing
medical education
plastic surgery
surgery
African experience
Nigerian surgery
stages of wound healing
phases of wound healing
collagen storage disease
wound Healing/endodontic courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
wound healing/cosmetic dentistry courses
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Healing and repair by Dr. Kachinda wezi 2018
Wound healing is a complex process involving inflammation, tissue regeneration, and scar formation. It can occur through regeneration of parenchymal cells or through the formation of granulation tissue and scarring. The key steps are inflammation, proliferation of fibroblasts and blood vessels to form granulation tissue, collagen deposition, and remodeling. Healing occurs through primary intention in clean closed wounds and secondary intention in open wounds with tissue loss. Many factors like nutrition, infection, age, and medications can influence the healing process.
Cutaneous wound healing
Cutaneous wound healing occurs through first or second intention. Primary union (first intention) involves clean surgical incisions approximated by sutures, resulting in relatively thin scar formation. Secondary union (second intention) involves larger defects without sutures, resulting in formation of granulation tissue and more substantial scarring due to wound contraction. The stages of wound healing include formation of a blood clot, granulation tissue, re-epithelialization, collagen deposition, and scar formation.
Wound healings
The document discusses the three main phases of wound healing: inflammatory, proliferative, and remodeling. In the inflammatory phase, blood vessels constrict and immune cells are recruited to fight infection. The proliferative phase involves new tissue growth through granulation, collagen deposition, angiogenesis and epithelialization. Finally, the remodeling phase lasts for months as the scar matures and collagen is reorganized. Through these coordinated phases, the body works to close and resurface wounds.
Acromegaly 19.07.08
Wound healing involves four phases - haemostasis, inflammation, proliferation, and remodeling. In haemostasis, platelets form clots to stop bleeding. Inflammation brings immune cells to fight infection and remove debris. Proliferation involves new tissue growth through cells like fibroblasts, endothelial cells, and keratinocytes. Remodeling strengthens the wound over months through collagen remodeling. Nutrition, infection, diabetes and other systemic factors can impact wound healing. Occlusive dressings aid healing by keeping wounds moist and preventing infection.
WOUND HEALING AND ENDODONTICS
The document discusses various topics related to wound healing, including:
- The classification, types, and factors that affect wound healing.
- The two main processes in healing are regeneration (restoration of original tissues) and repair (fibrosis and scarring).
- Healing occurs through the stages of inflammation, clearance of debris, and ingrowth of granulation tissue.
- Specific examples discussed include healing of fractures, non-surgical root canals, excisional dentoalveolar wounds, replanted teeth, and dental implants.
- Complications like infection, delayed/non-union can occur if healing is disrupted.
Inflammatory Principles & Athletic Rehab
The document summarizes the inflammatory process and its phases:
1) The acute/early inflammatory phase involves vasodilation, increased permeability and edema, phagocytosis by immune cells to remove debris.
2) The proliferation phase involves tissue regeneration through re-epithelialization, angiogenesis and fibroplasia to form new scar tissue.
3) During the remodeling phase lasting up to a year, collagen is reorganized and strengthened to gradually restore function.
Healing and repair
1. Tissue repair involves regeneration of injured tissue or replacement by connective tissue scarring. It involves cell proliferation and interaction between cells and the extracellular matrix.
2. Tissues are divided into continuously dividing, stable, and permanent groups based on their ability to proliferate. Continuously dividing tissues like skin regenerate easily while permanent tissues like neurons cannot regenerate after injury.
3. Growth factors and the extracellular matrix play important roles in tissue repair by stimulating cell growth and movement. Repair occurs through regeneration in labile tissues and scarring in others when injury is too severe for regeneration.
Wound healing
Detailed presentation on wounds, classification, phases of healing and management for resident doctors, medical students and nurses
Wound healing
This document provides an overview of wound healing. It begins with definitions of regeneration, repair, and the two types of wound healing: primary intention and secondary intention. For regeneration and repair, it describes the molecular events of cell growth, proliferation, and extracellular matrix formation. It then covers the stages of primary and secondary wound healing in more detail. Specialized tissue healing like fractures is also summarized. Factors influencing wound healing and complications are listed. The document contains detailed information on the cellular and molecular processes involved in wound healing.
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...CLOVE Dental OMNI Hospitals Andhra Hospital
This document discusses wound healing and fracture healing processes. It describes the phases of wound healing including inflammation, granulation tissue formation, and wound contraction in primary and secondary healing. Factors influencing wound healing like infection, nutrition and diabetes are covered. Complications of healing such as hypertrophic scarring and keloid formation are mentioned. Commonly used wound healing materials like oxidized regenerated cellulose and Whitehead's varnish are briefly described. Fracture healing through procallus formation, osseous callus formation and remodeling is summarized.Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Wound healing in Dentis...
entist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Wound healing in dentistry.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
Subscribe our channel on youtube - Copy and paste this URL. https://www.youtube.com/channel/UC_gylEXTrjmEbbOTSXjuZ4Q/videos?view_as=public
Follow us on Slideshare.
Ug wound healing
basic concepts of tissue injury and healing process. emphasis placed on primary and secondary type of wound healing.
Tissue healing
Tissue healing involves regeneration and repair. Regeneration is the proliferation of original cells to restore tissues, while repair is the replacement of injured tissue with fibrous scar tissue. Some key points about tissue healing include:
- Regeneration occurs through growth factors stimulating cell proliferation and the regeneration of parenchymal cells.
- Repair involves the formation of granulation tissue from fibroblasts and new blood vessels, followed by wound contraction.
- Skin wound healing occurs primarily through regeneration, while fractures heal through formation of a callus during repair.
- Nerve and muscle tissues have limited regenerative abilities.
Wound healing
The document discusses the stages of wound healing including hemostasis, inflammation, proliferation, and remodeling, and the factors that influence wound healing such as wound type, patient health, and environmental conditions. It also covers abnormal wound healing which can result in hypertrophic or keloid scarring, and treatments for scarring including pressure therapy, steroid injections, and surgery.
Physiology of wound healing
Wound healing is a complex process involving four cell types that occurs in distinct phases: hemostasis, inflammation, proliferation, and maturation. Chronic wounds get stuck in the inflammation phase due to factors like increased cytokines, altered growth factors, and senescent cells. Tissue engineering techniques aim to promote healing by combining cells and biomaterials into functional tissues. One such technique uses autologous cancellous bone mixed with stem cells and allogeneic platelet gel growth factors to treat non-union bone fractures.
What's hot (19)
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...
14. wound healing (65) Dr Rahul Tiwari OMFS SIBAR Institute of Dental Science...
Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Wound healing in Dentis...
Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Wound healing in Dentis...
Similar to Wound healing (cutaneous)
Pathways for cellular uptake of nanoparticles.pptx
PROVIDES.
1. Entry of nanoparticles into body.
2.Formation of protein corona.
3.Cellular uptake.
4.Endocutotic pathways..
a. Phagocytosis.
b. Clathrin mediated.
c. Caveolae mediated.
d. Pinocytosis.
5.Fate of Nanoparticle.
6.Effects.
7.conclusion
Macrophage phenotype
A brief introduction of macrophage phenotype including research timelines, the pathways and functional of M1 and M2 phenotype.
Gametogenesis, fertilization, implantation and 1st wk development
its a presentation of introduction of embryology, gametogenesis, fertilization, implantation and 1st wk of development.
Inflammation
Inflammation is the body's protective response to injury or infection. The document discusses the key components of acute and chronic inflammation. Acute inflammation is characterized by rapid onset, short duration, and features like fluid exudation and neutrophil accumulation. Chronic inflammation lasts longer and involves lymphocytes, macrophages and plasma cells. The inflammatory response involves vascular changes like vasodilation and increased permeability, as well as cellular events like leukocyte recruitment and activation through processes such as chemotaxis and phagocytosis. Chemical mediators released include histamine, prostaglandins, leukotrienes and cytokines which regulate the inflammatory response.
Minarcik robbins 2013_ch3-regen
1. Healing is a reparative tissue response to injury that often leads to fibrosis, while regeneration replaces lost structures through cell proliferation.
2. The healing process involves inflammation, proliferation of connective tissue cells, angiogenesis, collagen deposition, tissue remodeling, and wound contraction.
3. Angiogenesis, stimulated by growth factors like VEGF, is key to forming granulation tissue that fills wounds and promotes healing.
spermcryoperservation-160417132445.pptx
This document discusses sperm cryopreservation, including an overview of current technologies, factors affecting cryopreservation results, sperm cryodamage, and optimizing sperm cryopreservation. It describes techniques for slow freezing, rapid freezing, and vitrification. Factors affecting optimization include biological factors, technical factors, genetic factors, and cryopreservation medium. Cryopreservation may induce DNA damage, though studies have found mixed results. Studies on reproductive outcomes using cryopreserved versus fresh sperm in ICSI have also found mixed results depending on the source and quality of the sperm. Future work is still needed to fully understand cryopreservation's effects.
L4) Wound Healing & Management (OUTDATED 438).pdf
The document discusses wound healing, scarring, and pressure sores. It covers the basic principles, classification, phases of wound healing, collagen types, factors affecting healing, and abnormal scarring outcomes like hypertrophic scars and keloids. The phases of wound healing are inflammatory, proliferative, and remodeling. Fibroblasts are the major cell involved in the proliferative phase. Secondary healing involves more contraction than partial thickness healing. Clean-contaminated wounds result from a small breach entering the respiratory, gastrointestinal, or genitourinary tract. An ideal scar is flat, flexible, and matches surrounding skin color without pain or movement restriction. Preventing hypertrophic scarring involves tension-free closure with minimal tissue
Healing following pdl surgeries.pptx
Periodontal wound healing involves four overlapping phases - exudative, resorptive, proliferative, and regenerative. The proliferative phase includes re-epithelialization, fibroplasia, granulation tissue formation, collagen deposition, angiogenesis, and wound contraction. Growth factors play an important role in regulating periodontal wound healing. Healing after periodontal procedures like scaling and root planing, curettage, ultrasonic curettage, and gingivectomy depends on the extent of tissue disruption and follows a timeline of inflammatory response, epithelial migration, granulation tissue formation, collagen deposition and remodeling.
Wound healing
This presentation is on wound healing with special emphasis on healing in the oral cavity such as healing of extraction socket etc.
Erika amberson apoptosis extra credit
Apoptosis, or programmed cell death, is an essential process for multicellular organisms where individual cells undergo orderly death. It was first observed in the 1800s and research has identified key genes and pathways involved. Apoptosis is triggered through either an extrinsic or intrinsic pathway that activates caspase enzymes leading to cell shrinkage, nuclear fragmentation, and phagocytosis without inflammation. Dysregulation of apoptosis contributes to diseases like cancer, autoimmune disorders, and neurodegenerative diseases. Future research aims to better understand how cells are selected for death and how to manipulate apoptosis for therapeutic purposes.
Immune mechanisms
The document summarizes the architecture of the immune system. It describes the mononuclear-phagocytic system (MPS), also known as the monocyte macrophage system or reticuloendothelial system, as the second line of defense that is phylogenetically primitive but effective in host protection even without B and T lymphocytes. It also describes the lymphoid component, which includes primary organs like the thymus and peripheral organs like lymph nodes and spleen. The MPS originates from hematopoietic stem cells in the bone marrow and differentiates into monocytes and tissue-based macrophages that carry out phagocytosis and antigen presentation.
Chronic inflamation
This document outlines the key events and processes in acute inflammation. It begins by describing the sequence of vascular and cellular events that occur, from initial vasodilation and increased permeability to leukocyte migration and phagocytosis. It then discusses the roles of chemical mediators like histamine, cytokines, and eicosanoids. The three potential outcomes of acute inflammation are also noted: complete resolution, scar formation, or progression to chronic inflammation. Morphological patterns of acute inflammation like serous, fibrinous, and purulent exudates are also reviewed.
Skin donation, skin banking, skin culture
1. Skin banking involves procuring skin from donors after death, processing it which may include cryopreservation or lyophilization, and storing it to be used for burn patients or other wounds.
2. The first skin bank was established in 1971 and they continue to improve techniques like reducing immunogenicity and potential for disease transmission.
3. Skin culture techniques also allow creating skin substitutes using fibroblasts, keratinocytes and endothelial cells grown on collagen gels or cadaver dermis in organotypic culture.
Repair and Regeneration.pptx
This document discusses concepts related to tissue repair and regeneration. It defines regeneration as the complete renewal of lost tissue architecture and function, while repair involves restoration of tissue continuity through scar formation. The key processes involved in repair are cell proliferation, growth factor signaling, stem cell differentiation, angiogenesis, connective tissue deposition, and remodeling. Growth factors stimulate cell growth and migration to form new tissue, while stem cells develop into specialized cells that repopulate injured areas. Overall repair restores structure, but regeneration fully restores the original tissue.
Wound healing in Perio - Dr. Malvika Thakur
Wound healing is a complex process involving regeneration and repair. It consists of three overlapping phases - inflammatory, proliferative, and remodeling. In the inflammatory phase, coagulation and platelet aggregation form a fibrin clot and recruit inflammatory cells. The proliferative phase involves re-epithelialization through keratinocyte migration and proliferation. Fibroblasts are activated and form granulation tissue through angiogenesis and collagen deposition. Myofibroblasts aid wound contraction in the final remodeling phase. Growth factors influence each phase of wound healing after periodontal and oral procedures.
Physiology of wound healing
The document summarizes the key stages of wound healing:
1. Hemostasis, where damaged blood vessels constrict to stop bleeding and a clot forms via platelet activation and coagulation pathways.
2. Inflammation, where neutrophils and macrophages are recruited to the wound to remove debris and fight infection over the first few days.
3. Proliferation, the longest phase, involves new blood vessel growth (angiogenesis), fibroblast migration and collagen deposition to form granulation tissue, re-epithelialization of the wound edges, and wound contraction over weeks.
4. Remodeling lasts up to 2 years as scar tissue matures and strengthens.
Limbal stem cell Deficiency; amniotic membrane transplantation
This document summarizes limbal stem cell deficiency (LSCD), its causes, clinical manifestations, diagnosis, and treatment options. It discusses that limbal stem cells reside in the palisades of Vogt and are responsible for corneal epithelial renewal. LSCD can be caused by injuries or diseases and results in conjunctivalization of the cornea. Treatment options include conservative management, surgical removal of conjunctival epithelium and transplantation of limbal stem cells through various methods like conjunctival limbal autograft or cultured limbal stem cell transplantation.
Tissue repair
Tissue repair occurs through regeneration, healing, or fibrosis. Regeneration replaces damaged tissue, healing involves connective tissue deposition, and fibrosis is extensive collagen deposition. The cell cycle consists of growth, DNA synthesis, mitotic, and resting phases regulated by checkpoints. Tissues have proliferative capacities ranging from continuously dividing stem cells to permanently non-dividing cells. Growth factors regulate cell proliferation through receptor signaling. The extracellular matrix provides structure and signals to regulate cell behavior during tissue regeneration and repair.
2 inflam
This document outlines the process of acute and chronic inflammation. It describes the vascular and cellular events that occur during acute inflammation, including vasodilation, increased vascular permeability, leukocyte extravasation, chemotaxis, phagocytosis, and the three potential outcomes of resolution, scarring, or chronic inflammation. Chronic inflammation is characterized by long-term involvement of lymphocytes, macrophages, and other cells. Granulomatous inflammation forms distinct nodules containing fibroblasts, lymphocytes, histiocytes, and sometimes multinucleated giant cells.
healing regeneration and repair mechanism.pptx
This document provides an overview of healing, regeneration, and repair mechanisms in the body. It discusses the processes of regeneration and repair, the phases of wound healing including hemostasis, inflammation, granulation tissue formation, and maturation. It also covers healing of different tissue types like skin wounds (primary and secondary healing) and bone fractures (primary and secondary healing). Local factors like infection and systemic factors like diabetes that can influence the healing process are also summarized.
Similar to Wound healing (cutaneous) (20)
Pathways for cellular uptake of nanoparticles.pptx
Pathways for cellular uptake of nanoparticles.pptx
Gametogenesis, fertilization, implantation and 1st wk development
Gametogenesis, fertilization, implantation and 1st wk development
Limbal stem cell Deficiency; amniotic membrane transplantation
Limbal stem cell Deficiency; amniotic membrane transplantation
More from Satish Kumar
Contralateral c7 CC7 transfer
This document discusses contralateral C7 transfer, a surgical procedure where the unaffected C7 nerve root is used to reinnervate nerves on the affected side for patients with brachial plexus injuries and total root avulsions. It can be done in a single stage by directly coapting the C7 to the recipient nerve, or in a staged procedure using a vascularised ulnar nerve graft to allow for nerve growth. The C7 is used because its muscles are cross-innervated, minimizing function loss on the normal side. Careful patient selection and post-operative physical therapy are important for achieving reinnervation and return of motor function on the affected side.
Thumb hypoplasia - congenital hand III
This document discusses different types of congenital thumb hypoplasia, including 10 specific types. It covers the development and anatomy of the thumb, provides detailed descriptions of each type of hypoplasia, and discusses approaches to management and treatment, including surgical techniques to address deficiencies in the first webspace, instability of joints, and lack of mobility. The goal of treatment is to reconstruct a functional thumb with a stable joint, adequate webspace, and motor function for pinching and grasping.
Craniofacial Microsomia and Hemifacial Atrophy
Craniofacial microsomia involves congenital malformations of structures arising from the first and second branchial arches. It can cause deformities of the orbit, mandible, ear, nerves and soft tissues that range from mild to severe. The etiology is unclear but may involve vascular perturbations, teratogen exposure or neural crest pathology. Treatment involves surgery to correct deformities such as mandibular distraction, commissuroplasty or facial reanimation procedures.
Cephalometry and occlusion of teeth
Cephalometry involves taking standardized lateral radiographs of the head to measure and analyze the relationships between craniofacial structures and teeth. Key points analyzed include angles relating the maxilla and mandible to cranial landmarks, dental angulation and relationships, and facial heights and proportions. Occlusion refers to the contact relationship between teeth during jaw movements. Normal occlusion involves the maxillary first molar cusps fitting into grooves of the mandibular molars. Malocclusions are classified as Class I, II, or III depending on the anteroposterior positioning of the maxillary molars relative to the mandibular molars and jaws.
BOTOX - Botulinum toxin in aesthesis
Botulinum toxin is produced by Clostridium botulinum bacteria. It works by blocking the release of acetylcholine at neuromuscular junctions, preventing muscle contraction. It has been used since the 1980s to treat medical conditions involving muscle overactivity like strabismus and dystonia. In the 1990s, its use was explored for cosmetic purposes to reduce facial wrinkles. The FDA approved its use for frown lines in 2002 and excessive underarm sweating in 2004. It is injected into specific facial muscles to weaken them and smooth wrinkles. Common sites include the glabella, forehead, crow's feet, bunny lines, marionette lines and platysmal bands. Potential complications include
Face lift - Rhytidectomy
This document provides information on facelift procedures. It discusses facial aging changes and facelift anatomy. Several facelift techniques are described including subcutaneous, superficial musculoaponeurotic system (SMAS), extended SMAS, lateral SMAS-ectomy, platysma-SMAS plication, deep plane, short scar, and secondary facelifts. Neck rejuvenation techniques like submental dissection and platysmaplasty are also outlined. Potential complications are noted. The goal of facelifts is to lift tissues while avoiding an operated look through careful surgical planning and technique.
Liposuction
This document provides an overview of liposuction procedures. It discusses the basic science and anatomy related to liposuction, patient assessment and selection criteria, surgical techniques including tumescent liposuction and different modalities like ultrasound-assisted and laser-assisted liposuction. Post-operative care and potential complications are also reviewed. The document aims to inform practitioners on best practices for liposuction to achieve optimal contouring results.
Dupuytren's contracture
Dupuytren's contracture is a progressive fibroproliferative disease affecting the palmar fascia that can cause fingers to bend into the palm. It typically affects middle-aged Caucasian men and has genetic and environmental risk factors. Physical exam reveals nodules and cords in the palm which can cause finger contractures over time. Treatment options range from minimally invasive needle fasciotomy or collagenase injections to more extensive fasciectomy surgery to remove diseased fascia. Recurrence is common, especially in patients with more severe disease.
Antero Lateral thigh flap
This document summarizes the anterolateral thigh (ALT) flap, including:
1) The ALT flap has reliable blood supply from branches of the lateral circumflex femoral artery and can provide skin, muscle, fascia and a long pedicle.
2) The anatomy is variable but the flap is typically based on musculocutaneous perforators from the descending branch of the lateral circumflex femoral artery.
3) The ALT flap has been used successfully for reconstruction of the head and neck, esophagus, abdomen, breast, extremities and perineum, with success rates over 95% and versatility in design.
4) Advantages include reliable anatomy, long pedicle, versatility
Anatomy of eyelid and eyelid reconstruction
The document provides an overview of eyelid anatomy and techniques for eyelid reconstruction. It describes the layers, muscles, nerves and blood supply of the eyelid. Functions include spreading secretions, tears and blinking. Reconstruction methods are classified by defect size and include direct closure, lateral cantholysis, semicircular flaps, lid switch flaps, Cutler-Beard procedure, forehead flaps, Tripier flaps, Hughes flaps and cheek rotation flaps to reconstruct the anterior or posterior lamella. The goal is to reestablish eyelid function and protection of the eye while achieving reasonable cosmesis.
Gastrocnemius flap
1. The gastrocnemius muscle consists of medial and lateral heads that are supplied by the medial and lateral sural arteries respectively.
2. The medial gastrocnemius flap is most commonly used due to its large size and reliable vascular pedicle. It can be raised as a muscle or musculocutaneous flap to cover defects of the upper leg and knee.
3. The lateral gastrocnemius flap is smaller but can be used for smaller defects of the upper lateral leg and knee. Both flaps have consistent anatomy and can be reliably elevated based on the dominant sural artery pedicles.
Zygoma fractures
1) Fractures of the zygoma are commonly caused by road traffic accidents and assaults, with the left side more frequently involved than the right.
2) Classification systems categorize fractures based on the location and degree of displacement. Surgical approaches are determined by the fracture pattern and may involve extraoral or intraoral incisions.
3) Treatment involves closed or open reduction and fixation using methods like K-wires, plates and screws to properly align the zygomatic arch, frontal bone sutures, and orbital rim/floor. Complications can include sinusitis, malunion, diplopia or nerve numbness if not addressed correctly.
Transplantation biology
Transplantation involves grafting tissue from one site to another or from one individual to another. Major advances include the first kidney transplant in 1955 and hand transplant in 1998. Survival depends on preventing rejection through immunosuppression. The goal is transplantation is to replace failed organs and tissues. Rejection occurs via the major histocompatibility complex and immune cells such as T cells, B cells, macrophages, and natural killer cells. Immunosuppression drugs help prevent rejection and include corticosteroids, calcineurin inhibitors, antiproliferatives, monoclonal antibodies, and mTOR inhibitors. Future areas of focus include inducing immunological tolerance through clonal deletion, anergy, or suppression.
More from Satish Kumar (13)
Recently uploaded
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Adhd Medication Shortage Uk - trinexpharmacy.com
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
A Classical Text Review on Basavarajeeyam
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Do you have abnormal smell after periods? It may be vaginitis. Do not worry, herbal medicine Fuyan Pill can help you get a cure.
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...rightmanforbloodline
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versio
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versionshare - Lions, tigers, AI and health misinformation, oh my!.pptx
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
The Best Ayurvedic Antacid Tablets in India
Treat the symptoms of indigestion, heartburn and stomach reflux with the 10 Best Ayurvedic Antacid Tablets in India.
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Learn about body grief and ways to cope with it. We will also explore methods to heal from this challenging experience.
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Recently uploaded (20)
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
Ear and its clinical correlations By Dr. Rabia Inam Gandapore.pptx
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
Post-Menstrual Smell- When to Suspect Vaginitis.pptx
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
share - Lions, tigers, AI and health misinformation, oh my!.pptx
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
Part II - Body Grief: Losing parts of ourselves and our identity before, duri...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptx
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Muscles of Mastication by Dr. Rabia Inam Gandapore.pptx
Wound healing (cutaneous)
- 3. SEMANTICS OF WOUND HEALING • • • 3-4 • 4-6
- 5. PHASES OF WOUND HEALING • • •
- 7. Fibrillar collagen and Tissue factor Platelet aggregation Provisional matrix Neutrophils (48 hrs) Monocytes/ Macrophages (48-72 hrs) Lymphocytes (5-7 days) Coagulation cascade Scaffold for cell recruitment Remove dead tissue. Prevent infection.
- 10. PROLIFERATIVE PHASE (DAY 4-21) • • •
- 12. GRANULATION TISSUE • • ECM FORMATION AND ANGIOGENESIS • •
- 15. PROLIFERATION – SWITCH OFF REMODELLING – SWITCH ON
- 21. RECOVERY OF STRENGTH • • COLLAGEN DEGRADATION VS SYNTHESIS • CROSS LINKING • • •
- 24. FACTORS AFFECTING WOUND HEALING SYSTEMIC FACTORS LOCAL FACTORS Age Obesity Smoking Nutrition Anemia Diabetes Malignancy Immunosupressive diseases Circulatory status Steroids/cytotoxic drugs Infections Mechanical factors Foreign bodies Venous or lymph stasis Hematoma Location of wound Size of wound Recurrent trauma Underlying disease like osteomyelitis/malignancy
- 25. PATHOLOGICAL ASPECTS OF REPAIR 1. 2. 3.
- 27. EXCESSIVE FORMATION OF REPAIR PROCESS • • •