blood transfusion
oral and maxillofacial surgery
introduction about blood transfusion which includes its defination and essential of blood transfusion in conditions like surgery, anaemia, hemorrhage, trauma .
precautions to be taken before transfusion of blood such as donor to be healthy , only compatible bood must be transfused , both matching and cross matching must be done.
blood storage : to be done in blood bank in refrigerator
blood groups and its compatibility : four blood groups A,B,AB,O
RH factor
precaution to be taken while transfusion of blood
indications of transfusion
complications of transfusion : immune complication
transfusion reactions includes allergy , febrile , hemolytic .
infectious complication
autologous transfusion
In case of haemophilic patient : rubber band extraction to be done which seprates the periodontal ligament fibres
in few sitting oral surgeon push the the rubber towards the apex of the tooth and this is how tooth pulls out of the socket ,
Blood transfusion is the process through which blood and blood products are transferred to circulation intravenously. Early transfusions used whole blood but modern medical practice commonly used components of blood.It helps to replace blood lost during injury or surgery. It is a life saving procedure. before transfusion of blood it is necessary to know your blood group type. As blood group o is considered as universal donor and blood group AB considered as universal accepter.
Blood transfusion are relatively safe but can be fatal if incorrectly administered. Donated blood can be processed into components such as PCV, FFP, Platelets, Cryoprecipitate. Doctors and nurses plays a major role in blood transfusion. They should follows all safety precautions throughout all steps of administrating procedure.
Blood transfusion is the process through which blood and blood products are transferred to circulation intravenously. Early transfusions used whole blood but modern medical practice commonly used components of blood.It helps to replace blood lost during injury or surgery. It is a life saving procedure. before transfusion of blood it is necessary to know your blood group type. As blood group o is considered as universal donor and blood group AB considered as universal accepter.
Blood transfusion are relatively safe but can be fatal if incorrectly administered. Donated blood can be processed into components such as PCV, FFP, Platelets, Cryoprecipitate. Doctors and nurses plays a major role in blood transfusion. They should follows all safety precautions throughout all steps of administrating procedure.
how to select a healthy donor & care of donor .A healthy donor is one of the most vital part of transfusion medicine for safe transfusion of blood & blood product
Blood Transfusion
Blood transfusion is the process of transferring blood or blood based products from one person into the circulatory system of another. Safe blood transfusion should be safe to both the donor and the recipient. Blood transfusions can be life saving in some situations such as -Massive blood loss due to trauma or can be used to replace blood lost during surgery.BT may also be used to treat a severe anemia orThrombocytopenia caused by a blood disease.People suffering from hemophilia or sickle disease may require frequent transfusion.
In this presentation I've tried to summarize classification of hemolytic anemia and in depth review of rbc membrane disorders like hereditary spherocytosis, hereditary elliptocytosis, enzymopathies of hemolytic anemia like g6pd disorder, pyruvate kinase disorders, hemoglobinopathies related to hemolytic anemia like thalassemia, sickle cell anemia and especially pathophysiology and mechanism of hemolysis either extravascular or intravascular. Hope it helps you understand the entity better.
how to select a healthy donor & care of donor .A healthy donor is one of the most vital part of transfusion medicine for safe transfusion of blood & blood product
Blood Transfusion
Blood transfusion is the process of transferring blood or blood based products from one person into the circulatory system of another. Safe blood transfusion should be safe to both the donor and the recipient. Blood transfusions can be life saving in some situations such as -Massive blood loss due to trauma or can be used to replace blood lost during surgery.BT may also be used to treat a severe anemia orThrombocytopenia caused by a blood disease.People suffering from hemophilia or sickle disease may require frequent transfusion.
In this presentation I've tried to summarize classification of hemolytic anemia and in depth review of rbc membrane disorders like hereditary spherocytosis, hereditary elliptocytosis, enzymopathies of hemolytic anemia like g6pd disorder, pyruvate kinase disorders, hemoglobinopathies related to hemolytic anemia like thalassemia, sickle cell anemia and especially pathophysiology and mechanism of hemolysis either extravascular or intravascular. Hope it helps you understand the entity better.
Blood transfusion - components , procedure , pre transfusion testing and comp...prasanna lakshmi sangineni
blod transfusion- introduction , procedure , pre transfusion tests , complications , characteristics of components and components usually used like packed red cells, FFP, platelet rich plasma, cryoprecipitate, albumin and other plasma derivatives
This PPT is basically based on the topic - Blood transfusion in Bailey & Love and mainly very useful for Final MBBS students.during their course as well as their in clinical practice.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
2. INTRODUCTION
Blood transfusion is the process of transferring
blood or blood components from one person
into the bloodstream of another person.
Transfusion may be done as a life saving
procedure to replace blood cells or blood
products lost through bleeding.
Blood transfusion is essential in conditions like
surgery, anemia, hemorrhage, trauma.
3.
4. PRECAUTIONS TO BE TAKEN BEFORE
TRANSFUSION OF BLOOD
• Donor must be healthy without any
diseases like syphilis, AIDS, etc.
• Only compatible blood must be
transfused and RH compatibility must
be confirmed.
• Both matching and cross-matching
must be done.
5. BLOOD STORAGE
Blood is stored in blood bank in refrigerator at 4 degree
celsius
RBC lose their ability to release Oxygen to the tissues of
recepient within 7 days
WBC are rapidly destroyed in the stored blood
Platelets are also destroyed at 4 degree celsius
Shelf life of stored blood in CPD solution is about 3
weeks when blood is stored in CPDA-I solution ,
storage life increased by 5 weeks
6. BLOOD GROUPS AND COMPATIBILITY
BLOOD GROUPS: the red cells contains agglutinogens named A &
B & the serum contains agglutinins named Anti A and Anti B
According to the presence or absence of the 2 agglutinogen A & B
there are 4 blood groups:
GROUPA – RBC contain A agglutinogen and serum contain Anti B
agglutinin
GROUP B – RBC contain B agglutinogen and the serum contain
neither Anti A nor Anti B agglutinin
GROUPAB – RBC contain both A&B agglutinogens and the
serum contains neither Anti A nor Anti B agglutinin
GROUP O – RBC contain neither A nor B agglutinogen and the
serum contains both Anti A and Anti B agglutinins
7.
8. This is an ANTIGEN found in the red cells
Human being can be divided into Rh +ive & Rh –ive group
Person with Rh +ive blood donot posses Rh antibody in the serum
Whether Rh +ive cell are infected into Rh –ive person antbody Rh
develops
First transfusion fails to produce any symptoms but further
transfusion will definetly produce serious reaction
Approx. 85% of population are Rh +ive
15% are Rh –ive
9. PRECAUTIONS TO BE TAKEN WHILE TRANSFUSING
BLOOD
• Apparatus for transfusion must be sterile
• The temperature of blood to be transfused
must be same as body temperature
• The transfusion of blood must be slow. The
sudden rapid infusion of blood into the body
increases the load on the heart result in
many complications.
10. INDICATIONS OF TRANSFUSION
• Loss of blood in an accident
• Bleeding disorder (haemophilia, christmas disease,
thrombocytopenic purpura)
• Supportive therapy in infection
• Septicaemia
• Carbon monoxide poisoning
• Pack cells are given in anaemias and leukaemias
• Whole blood transfusion is indicated in
erythroblastosis foetalis
• In case of burns blood is given as an adjunct to saline
therapy
• Major operations, where good amount of blood loss
(eg; radical mastectomy)
12. COMPLICATIONS OF TRANSFUSION
IMMUNE COMPLICATIONS
Haemolytic reactions :
a. Major (ABO) incompatibility reaction
• This is result of mismatched blood transfusion
• Majority of cases are due to technique errors like
sampling , labelling , dispatching, etc
• This causes intravascular haemolysis
Clinical features:
• Haematuria
• Pain in the loins
• Fever with chills and rigors
• Oliguria is due to the products of mismatched blood
transfusion blocking the renal tubules. it results in acute
renal tubular necrosis
13. b. Minor incompatibility reaction
• occurs due to extravascular haemolysis
• Usually mild, occurs at 2-21 days
• Occurs due to antibodies to minor antigens
• Malaise , jaundice and fever
14.
15. Non-haemolyticreactions
a. Febrile reaction
• Occurs due to sensitisation to WBCs or platelets
• Increased temperature-no haemolysis
b. Allergic reaction
• Occurs due to plasma products ; manifest as chills, rigors
and rashes all over
c. Transfusion- related acute lung injury (TRALI)
• Anti-leucocyte antibodies cause patient’s white cells to
aggregate in pulmonary circulation
d. Congestive cardiac failure (CCF)
• CCF can occur if whole blood is transfused rapidly in
patients with chronic anaemia.
17. AUTOLOGOUS TRANSFUSION
Safest form of blood transfusion and involves pre-operative
collection of patient’s own blood for reinfusion during an
elective surgery (only in cases where haemoglobin is more than
11 gm% and hematocrit value of 34%).
One or two units of blood are safely drawn and stored one or two
weeks prior to surgery.
The patient is put on good nourishing diet for haemopoietic
regeneration and build up of haemoglobin level prior to surgery.
ADVANTAGES
1. Autotransfusion eliminates the risk of viral hepatitis and HIV
infection
2. It avoids blood incompatibility and other transfusion reactions
3. It ensures the availability of blood especially when no donor is
available
18. Cross matching is mandatory prior to
transfusion to avoid incompatibility on
account of misidentification.