Every year on November 14, World Diabetes Day brings diabetes to the attention of the world. Learn more about the 2009-2013 campaign!
Contact the World Diabetes Day team at wdd@idf.org if you have any questions.
Symptoms of Pre-Diabetes and Diabetes Prevention TipsInovaHealth
Learn about pre-diabetes and how asses your risk and tips on preventing diabetes from Inova Medical Group physicians.
Learn more about Inova Medical Group at www.inovamedicalgroup.org.
Educational Grand Rounds: Diabetes and Lifestyle ModificationS'eclairer
Dr. Zahida Chaudhary presents a slide deck on Diabetes along with James Ellermeyer as they discuss what our society is doing to contribute to the problem and what we can do to change it in our own lives on a case by case basis.
Presentation performed for highlighting VERIFY: Galvus-met trials superiority in managing newly diagnosed DMT2 patients with preserving B cell function, evidence.
The World Heart Foundation organizes World Heart Day, an international campaign held on September 29 to inform people about cardiovascular diseases, which are the biggest cause of death. The day promotes preventative measures to reduce the risk of cardiovascular diseases.
Medical Research Map is a joint effort of Sitra, Finnish medical faculties and Pharma Industry Finland to create an overview on the Finnish medical research market and to discover new cooperation opportunities between universities and pharma companies.
Ernst & Young Oy (“EY”) has on Sitra’s request interviewed 24 experts from pharma companies, universities and university hospitals, covering all Finnish medical faculties and around 75% of pharmaceutical business in Finland.
In addition, an online questionnaire was conducted to find the most relevant research areas and methods from the perspectives of global pharma industry and Finnish medical faculties.
Symptoms of Pre-Diabetes and Diabetes Prevention TipsInovaHealth
Learn about pre-diabetes and how asses your risk and tips on preventing diabetes from Inova Medical Group physicians.
Learn more about Inova Medical Group at www.inovamedicalgroup.org.
Educational Grand Rounds: Diabetes and Lifestyle ModificationS'eclairer
Dr. Zahida Chaudhary presents a slide deck on Diabetes along with James Ellermeyer as they discuss what our society is doing to contribute to the problem and what we can do to change it in our own lives on a case by case basis.
Presentation performed for highlighting VERIFY: Galvus-met trials superiority in managing newly diagnosed DMT2 patients with preserving B cell function, evidence.
The World Heart Foundation organizes World Heart Day, an international campaign held on September 29 to inform people about cardiovascular diseases, which are the biggest cause of death. The day promotes preventative measures to reduce the risk of cardiovascular diseases.
Medical Research Map is a joint effort of Sitra, Finnish medical faculties and Pharma Industry Finland to create an overview on the Finnish medical research market and to discover new cooperation opportunities between universities and pharma companies.
Ernst & Young Oy (“EY”) has on Sitra’s request interviewed 24 experts from pharma companies, universities and university hospitals, covering all Finnish medical faculties and around 75% of pharmaceutical business in Finland.
In addition, an online questionnaire was conducted to find the most relevant research areas and methods from the perspectives of global pharma industry and Finnish medical faculties.
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essential information about obesity prevalence, risks, complications, and preventive measures and procedures to control weight and obesity, especially in gulf countries, particularly, Saudi Arabia.
This lecture is prepared and submitted in Arabic language,for Arabic people, and who understand Arabic, be able to watch and understand it easily, and also to be able to get and apply the practical instructions in their own life and change their food habits to get the optimal benefits for themselves and their families.
The 2009–2013 campaign calls on all those responsible for diabetes care to understand diabetes and take control. For people with diabetes, this is a message about empowerment through education. For governments, it is a call to implement effective strategies and policies for the prevention and management of diabetes to make sure that their citizens with and at risk of diabetes receive the best possible care. For healthcare professionals, it is a call to improve knowledge so that evidence-based recommendations are put into practice. For the general public it is a call to understand the serious impact of diabetes, to know how to identify the condition and, where possible, know how to avoid or delay diabetes and its complications.
World Down Syndrome Day is observed on the 21st March of every year. This day witnesses the presence of people who suffer from Down syndrome, and those who live and work along with them, participating and organising various events and activities to raise awareness about the syndrome. The aim behind this celebration is to unite together with a common voice and advocate the rights of people with down syndrome.
WHO and International Agency for Research on Cancer (IARC) supports Union for International Cancer Control (UICC) to promote ways to ease the global burden of cancer.
On Monday, June 10, Bread for the World and Concern Worldwide U.S. will host an event in Washington, D.C. called “Sustaining Political Commitments to Scaling Up Nutrition” to celebrate progress made over the last 1,000 days and look ahead to the possibilities and opportunities to accelerate progress towards a world free of malnutrition.
La campagne 2009-2013 invite tous les acteurs du diabète à comprendre le diabète et en prendre le contrôle. Pour les personnes atteintes de diabète, il s’agit d’un message d’émancipation par l’éducation. Pour les gouvernements, ce thème vise à l’implémentation de stratégies et politiques efficaces de prévention et de contrôle du diabète afin de préserver la santé de leurs citoyens atteints de diabète ou à risque. Pour les professionnels de la santé, il s’agit d’un appel à améliorer les connaissances afin que les recommandations ayant fait leurs preuves soient mises en pratique. Pour le public, il s’agit de comprendre l’importance de l’impact du diabète et, lorsque possible, d’éviter ou de retarder le diabète et ses complications.
La campaña del 2009-2013 hace un llamamiento a todos los responsables de la atención de la diabetes a entender la diabetes y tomar control. Para las personas con diabetes éste es un mensaje sobre la capacitación a través de la educación. Para los gobiernos, es un llamamiento para que se implementen estrategias y políticas efectivas para la prevención y el control de la diabetes que aseguren que los ciudadanos con diabetes y en riesgo de desarrollarla reciben la mejor atención posible. Para los profesionales de la salud es un llamamiento para mejorar su conocimiento a través de recomendaciones basadas en evidencia, y poner dichas recomendaciones en práctica. Para el público en general es una llamada a entender el serio impacto que tiene la diabetes
Lancée en 1991, la Journée Mondiale du Diabète est une initiative de la Fédération Internationale du Diabète (FID) et de l'Organisation Mondiale de la Santé (OMS) créée en réponse à l'inquiétude suscitée par l'incidence croissante du diabète dans le monde. En décembre 2006, l'Assemblée générale des nations unies a approuvé la résolution 61/225, qui fait de la Journée Mondiale du Diabète une journée officielle des nations unis, à compter de 2007.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
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3. Every year on November 14, World Diabetes Day brings diabetes to the attention of the world.
4. November 14 is the birthday of Frederick Banting, one of the discoverers of insulin. (c) Banting House National Historic Site of Canada
5. The theme is set by the International Diabetes Federation and the World Health Organization.
6. In 2006, the United Nations passed resolution 61/225. It asks the world to observe November 14 as World Diabetes Day and to take action to address the diabetes threat.
13. In 2007, the World Diabetes Day logo incorporated the diabetes circle.
14.
15. Use the blue and the circle to show you care Image sources: http://spaaroundtheworld.wordpress.com/about/ http://diabetestaskforce.org http://www.cbs.umn.edu/studentservices/involvement/bwb.shtml http://www.flickr.com/photos/mcbill/2081463065/