Chronotherapy is the treatment of illness or disorders by administering drugs at times that are in harmony with the body's circadian rhythms. Circadian rhythms are 24-hour cycles that regulate essential functions and processes like sleep, temperature, and organ function. There is evidence that timing medication doses to match circadian rhythms can increase benefits and reduce side effects. Specifically for hypertension, the normal daily dip in blood pressure at night is disrupted, increasing cardiovascular risk. Studies show administering blood pressure medications at bedtime helps control blood pressure and reduces cardiovascular events and organ damage compared to other dosing times.