A look into why the environment around you can have dramatic effects on your ability to maintain a healthy weight.

1. Weight Loss Not to be Taken Lightly Why Losing Weight in a Healthy Manner and Keeping it Off is Not Just About Calories Presented By; Dr. Don Harris Clinical Nutritionist

2. Disclaimer The information given and discussed in this presentation is for information and research purposes only and is not intended to prescribe treatment

3. Dr. Don E. Harris Bridgewater State College 1986 BS Biology BS Psychology Brandies University 1987 Nutrition National College of Health Science 1992 BS Human Biology Doctor of Chiropractic American/International Society of Clinical Nutritionists Expected 2010 1992 to Present President of Initium Center for Integrative Health Care 2006 to present President of Harris: Advantage Health > 2,000 hours in Post Doctoral Nutrition 20 Years in Practice Specializing in Clinical Nutrition and Inflammatory Conditions Related to Aging

5. A Functional Medicine/Clinical Nutrition health care practice dedicated to assisting clients learn how each individual can alter their Lifestyle to live a life. Longer/Healthier

8. Endocrine Disorders Inflammatory Conditions Excessive Caloric Intake Lack of Caloric Expenditure Insulin Resistance/Metabolic Syndrome Nutritional Deficiencies G.I. Dysfunction Allergies Toxic Environment/Liver Detox Auto-Immune Disease Weight Loss; N ot to be Taken Lightly

9. Digestion & Absorption Detoxification & Elimination Immune Imbalances Endocrine Imbalances DIET Environment Daily Activities

12. Leading Causes of Death in the United States 1900 Infectious Illness 1.Pneumonia/Flu 2. Tuberculosis 3. Dysentery 4.Heart Disease 8. Cancer 7. Accidents 6. Kidney Infections 5. Stroke 10. Diphtheria 9. Senility 1.Heart Disease 2.Cancer 3.Stroke 7.Pneumonia/Flu 5. Accidents 4.Lung Disease 8.Alzheimer’s 9.Kidney Infection 10. Liver Disease 6.Diabetes 2008 Chronic Inflammation 70% 66% 1.8%

15. Overall Male Female Japan 74.5 71.9 77.2 Australia 73.2 70.8 75.5 France 73.1 69.3 76.9 Sweden 73.0 71.2 74.9 Spain 72.8 69.8 75.7 Italy 72.7 70.0 75.4 Greece 72.5 70.5 74.6 Switzerland 72.5 69.5 75.5 Monaco 72.4 68.5 76.3 Andorra 72.3 69.3 75.2 San Marino 72.3 69.5 75.0 Canada 72.0 70.0 74.0 Netherlands 72.0 69.6 74.4 United Kingdom 71.7 69.7 73.7 Norway 71.7 68.8 74.6 Belgium 71.6 68.7 74.6 Austria 71.6 68.8 74.4 Luxembourg 71.1 68.0 74.2 Iceland 70.8 69.2 72.3 Finland 70.5 67.2 73.7 Malta 70.5 68.4 72.5 Germany 70.4 67.4 73.5 Israel 70.4 69.2 71.6 United States of America 70.0 67.5 72.6

16. Weight Loss Not to be Taken Lightly Obesity $92 Billion United States spends 2.1 TRILLION on health care annually United States spends $7,900/person on health care annually 78%, or $1.6 trillion annually – are for the treatment of preventable, lifestyle related conditions such as type II diabetes, obesity, and heart disease. United States spends 16% of GDP on health care annually Australia spends 8.8% of GDP on health care annually France spends 11.2% of GDP on health care annually Sweden spends 9.2% of GDP on health care annually Japan spends 8.2% of GDP on health care annually Spain spends 8.2% of GDP on health care annually http://www.photius.com/rankings/healthy_life_table2.html GDP of the United States 14.3 Trillion

19. Total Weight Loss Lean Body Mass -11 -13 +4 -11 DSP OTC Health Care Professional Vs. Over the Counter Weight Loss Programs

22. 1998 (*BMI  30, or about 30 lbs. overweight for 5’4” person) 2007 1990 No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30% Weight Loss Not to be Taken Lightly Obesity Trends Among U.S. Adults BRFSS 1990, 1998, 2007

23. Weight Loss Not to be Taken Lightly Obesity Trends Among U.S. Adults BRFSS 1985-1989 (*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%

24. Weight Loss Not to be Taken Lightly Obesity Trends Among U.S. Adults BRFSS 1990-1999 (*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%

25. Weight Loss Not to be Taken Lightly Obesity Trends Among U.S. Adults BRFSS 2000-2007 (*BMI ≥30, or ~ 30 lbs. overweight for 5’ 4” person) No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%

26. Height/Weight Based on the North American Association for the Study of Obesity Males 5’ 00” 122 5’ 01” 126 5’ 02” 131 5’ 03” 135 5’ 04” 139 5’ 05” 144 5’ 06” 148 5’ 07 152 5’ 08” 157 5’ 09” 161 5’ 10” 166 5’ 11” 171 6’ 00” 175 6’ 01” 179 6’ 02” 184 6’ 03” 189 6’ 04” 195 Females 4’ 10” 114 4’ 11” 118 5’ 00” 121 5’ 01” 124 5’ 02” 128 5’ 03” 131 5’ 04” 134 5’ 05” 137 5’ 06” 140 5’ 07 144 5’ 08” 147 5’ 09” 150 5’ 10” 153 5’ 11” 157 6’ 00” 161 15%-20% 20%-25%

27. Weight Loss Not to be Taken Lightly Approximate Grams Potential Calories Carbohydrate Glucose in Blood and Interstitial Fluids 20 Glycogen Liver 85 Muscles 350 80 1,820 340 1,400 Fat (Assuming 15% Body Fat) 10,500 94,500 Protein 10,500 42,000 TOTAL 138,320

29. By The Numbers Total Daily Calorie Needs (A) __________ __________ X ___________________ Divided By 4 = __________________ (A) Calories/Carbs/Day(40%) Grams/Carbs 1716 1716 686 171 __________ X ___________________ Divided By 4 = __________________ (A) Calories/Protein/Day(30%) Grams/Protein 1716 514 128 __________ X ___________________ Divided By 9 = __________________ (A) Calories/Fat/Day(30%) Grams/Fat 1716 514 57 How Many Calories Do You Need?

30. By The Numbers Total Daily Calorie Needs (A) __________ __________ X ___________________ Divided By 4 = __________________ (A) Calories/Carbs/Day(50%) Grams/Carbs 2300 2300 1150 / 686 287 (171) __________ X ___________________ Divided By 4 = __________________ (A) Calories/Protein/Day(15%) Grams/Protein 2300 330 / 514 86 (128) __________ X ___________________ Divided By 9 = __________________ (A) Calories/Fat/Day(35%) Grams/Fat 2300 805 / 514 8 9 (57) How Many Calories Do We Eat?

31. Weight Loss Not to be Taken Lightly Insulin Resistance and Weight Loss

32. Insulin Resistance and Weight Loss Whenever we're angry, scared, anxious, or tense, the brain produces hormones that trigger the adrenal gland to secrete cortisol and adrenaline: hormones specifically designed to incite the fight-or-flight response that was once crucial to our survival. Adrenaline's main role is to make you alert and focused, with exceptional concentration and memory. Cortisol helps increase heart and respiratory rates and getting your muscles tensed and ready. Since, physiologically speaking, your body thinks you've run a mile or two or done something active in response to the 'threat', the hormone sends signals to refuel the body as soon as possible. It's a biological green light to indulge in foods loaded with carbs and fat that leads to weight gain in the chronically stressed. It's a vicious cycle of stress, followed by elevated cortisol, followed by that foods you don't need.

33. While those physiological processes worked well for our prehistoric ancestors, they're not as useful in a world where physical dangers are seldom. The trouble is, whenever we're stressed these hormones are released into your system. Though adrenaline levels plummet as the stress subsides, cortisol remains in the body much longer. Insulin Resistance and Weight Loss

35. Your liver and muscles are not able to remove the increased blood sugar due to the increased cortisol. This also increases the output of insulin causing a condition known as insulin resistance. Research has found that fat cells deep inside the belly are especially good at attracting cortisol. Simply put, the cascade of responses caused by stress encourages the accumulation of excess 'stress fat', the layer of fat below the abdominal muscle. 'This creates &quot;toxic weight&quot; - or extra fat inside the abdomen - which is a type of fat on the body associated with death. This type of fat has been linked to heart disease, high blood pressure, stroke, cancer and diabetes. Insulin Resistance and Weight Loss

36. Metabolic syndrome begins years before obesity appears; millions of people who are not obese have metabolic syndrome, while nearly everyone who is obese or diabetic has metabolic syndrome. Insulin Resistance and Weight Loss Metabolic Syndrome This state of persistent increased levels of cortisol leads into insulin resistance. This is usually called metabolic syndrome, although some experts call it Syndrome X or prediabetes.

39. Liver Detox/Toxicity and Weight Loss Weight Loss Not to be Taken Lightly

40. For the first time in the history of the world, every human being is now subjected to contact with dangerous chemicals from the moment of conception until death. In the less than two decades of their use, the synthetic pesticides have been so thoroughly distributed throughout the animate and inanimate world that they occur virtually everywhere. Liver Detox/Toxicity and Weight Loss

41. Today, experts are asking whether environmental factors may also play a role not only in weight gain but also in the difficulty so many people have in losing and keeping weight off. Interestingly, the biggest weight increases population-wise closely mirror the largest increases in synthetic chemical use. Since many of these chemicals actually cause weight gain, this similarity seems more than coincidental. Liver Detox/Toxicity and Weight Loss &quot;One new chemical enters industrial use every 20 minutes only to join many hundreds of thousands of synthetic chemicals already in use.” As a result, the average person living in the developed world is now contaminated with up to 500 industrial toxins, few of which have been properly tested for harmful effects.&quot; Indeed, the US has only recently begun long-term research to establish a baseline for toxins in a portion of our population.

43. The liver is the major fat burning organ in the body and regulates fat metabolism by a complicated set of biochemical pathways. The liver can also pump excessive fat out of the body through the bile into the small intestines. If the diet is high in fiber, this unwanted fat will be carried out of the body via the bowel actions. Thus the liver is a remarkable machine for keeping weight under control, being both a fat burning organ and a fat pumping organ. If the diet is low in fiber, some of the fats (especially cholesterol) and toxins that have been pumped by the liver into the gut through the bile will recirculate back to the liver. If this recirculated fluid is high in fat and/or toxins, this will contribute to excessive weight. Liver Detox/Toxicity and Weight Loss

44. Liver Detox/Toxicity and Weight Loss Your weight is extremely important at keeping your liver healthy. This means avoiding as many damaging substances (like alcohol, caffeine, many medications, sugar, and trans fats) as possible, while embracing liver boosters. Strengthen your liver with milk thistle, and consider soluble fiber (pectin and psyllium seed) to help remove toxins from the body. Many middle-aged people with excess fat in the abdominal area have a &quot; fatty liver &quot;. In this condition the liver has stopped burning fat and has turned into a fat storing organ. It becomes enlarged and swollen with greasy deposits of fatty tissue. Those with a fatty liver will not be able to lose weight unless they first improve liver function.

48. Phases of Treatment Elimination Detoxification Calorie Restriction/Low Glycemic Program Nutraceaticals Phase I Phase II Phase III OPTIMAL FUNCTIONAL HEALTH Program Digestion/Absorption Detoxification/Elimination Endocrine Dysfunction Immune Imbalance Stress