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Vitamin D & Your Pooch
Dr. Preethi Sudarshanie Dassanayake (B.V. Sc. , M. Sc., MBA)
Veterinary Teaching Hospital, University of Peradeniya
Sri Lanka
Vitamin D
 Is a fat-soluble vitamin.
 A steroid vitamin.
 An essential vitamin for dogs.
 Is a family of compounds that are derived from cholesterol.
 Commonly found in two major forms (Vitamin D2 & D3).
 D2 – Known as Ergocalciferol (found in plants).
 D3 – Called as Cholecalciferol (found in animal tissues).
 D2 & D3 are inactive and in the category of Prohormones.
Vitamin D activation pathway
 Humans obtain sufficient amount of vitamin D through exposure to direct sunlight.
 Your pet cannot synthesize this vitamin through exposure to the sunlight.
 You have to supply it with foods or adding supplements.
 Vitamin D absorb in the small intestine but in inactive form.
 cholecalciferol (D3) 25- hydroxycholecalciferol (In the liver)
 25- hydroxycholecalciferol 1,25-dihydroxycholecalciferol (In the kidney)
 1,25- dihydroxycholecalceferol is known as Calcitriol (active form of vitamin D)
 Excess vitamin D deposit in adipose tissue.
Functions of Vitamin D
 Promotes calcium absorption in the gut.
 Maintains serum calcium and phosphate level.
 Prevent from hypercalcemic tetany
 Proper bone growth and bone remodeling.
 Facilitating healthy bones and teeth.
 Improves muscle strength.
 Improves immune function.
 Reduces inflammation (anti-inflammatory).
Functions …..
 Blood pressure control.
 Blood sugar level control.
 Protection from cancers.
 Regulating genes.
 Maintaining cell health.
The Association of American
Feed Control Officials (AAFCO)
Recommendation - 500 IU of
Vitamin D Per Kilogram of Dog
Food
IU means International Units.
1 IU = 0.025mcg
500 IU = 12.5 mcg
Vitamin D deficiency
 Bones become thin.
 Bones become brittle.
 Misshapen bones.
 Rickets.
Vitamin D toxicity
 Hypercalcemia.
 Loss of appetite.
 Weight loss.
 Excessive thirst.
 Frequent urination.
 Drooling.
 Vomiting.
 Muscle weakness.
 Soft tissue mineralization.
 Lameness.
 Disrupt normal skeletal development (pups).
Sources
 salmon
 Mackerel
 Sardines
 Shrimp
 Egg yolk
 Cod liver oil
 Fortified milk
 Yoghurt
 Cheese
 Tuna
 Beef liver
THANKS
Photo courtesy- Google Image

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Vitamin d & your pooch

  • 1. Vitamin D & Your Pooch Dr. Preethi Sudarshanie Dassanayake (B.V. Sc. , M. Sc., MBA) Veterinary Teaching Hospital, University of Peradeniya Sri Lanka
  • 2. Vitamin D  Is a fat-soluble vitamin.  A steroid vitamin.  An essential vitamin for dogs.  Is a family of compounds that are derived from cholesterol.  Commonly found in two major forms (Vitamin D2 & D3).  D2 – Known as Ergocalciferol (found in plants).  D3 – Called as Cholecalciferol (found in animal tissues).  D2 & D3 are inactive and in the category of Prohormones.
  • 3. Vitamin D activation pathway  Humans obtain sufficient amount of vitamin D through exposure to direct sunlight.  Your pet cannot synthesize this vitamin through exposure to the sunlight.  You have to supply it with foods or adding supplements.  Vitamin D absorb in the small intestine but in inactive form.  cholecalciferol (D3) 25- hydroxycholecalciferol (In the liver)  25- hydroxycholecalciferol 1,25-dihydroxycholecalciferol (In the kidney)  1,25- dihydroxycholecalceferol is known as Calcitriol (active form of vitamin D)  Excess vitamin D deposit in adipose tissue.
  • 4. Functions of Vitamin D  Promotes calcium absorption in the gut.  Maintains serum calcium and phosphate level.  Prevent from hypercalcemic tetany  Proper bone growth and bone remodeling.  Facilitating healthy bones and teeth.  Improves muscle strength.  Improves immune function.  Reduces inflammation (anti-inflammatory).
  • 5. Functions …..  Blood pressure control.  Blood sugar level control.  Protection from cancers.  Regulating genes.  Maintaining cell health.
  • 6. The Association of American Feed Control Officials (AAFCO) Recommendation - 500 IU of Vitamin D Per Kilogram of Dog Food IU means International Units. 1 IU = 0.025mcg 500 IU = 12.5 mcg
  • 7. Vitamin D deficiency  Bones become thin.  Bones become brittle.  Misshapen bones.  Rickets.
  • 8. Vitamin D toxicity  Hypercalcemia.  Loss of appetite.  Weight loss.  Excessive thirst.  Frequent urination.  Drooling.  Vomiting.  Muscle weakness.  Soft tissue mineralization.  Lameness.  Disrupt normal skeletal development (pups).
  • 9. Sources  salmon  Mackerel  Sardines  Shrimp  Egg yolk  Cod liver oil  Fortified milk  Yoghurt  Cheese  Tuna  Beef liver