Vascular access in Haemodialysis (2).pptxMithunAhmed5
national institute of kidney disease and urology (nikdu)
Dialysis access refers to the creation of an entrance way into the bloodstream so that the blood can be cleansed by the dialysis procedure. It is well established that dialysis cannot be provided without access.
The attainment and maintenance of a single reliable, long-lasting dialysis access with minimal complications continue to be challenging.
Achievement of such an access is associated with optimal patient clinical outcomes, superior quality of life, and minimal costs.
Vascular access in Haemodialysis (2).pptxMithunAhmed5
national institute of kidney disease and urology (nikdu)
Dialysis access refers to the creation of an entrance way into the bloodstream so that the blood can be cleansed by the dialysis procedure. It is well established that dialysis cannot be provided without access.
The attainment and maintenance of a single reliable, long-lasting dialysis access with minimal complications continue to be challenging.
Achievement of such an access is associated with optimal patient clinical outcomes, superior quality of life, and minimal costs.
Although large efforts are spent for creating fistula as the primary access, use of Hemodialysis Vascular catheters are still the major access on the first Hemodialysis session and after 4 month whether we would like it or not.
"USRDS 2013"
Steal syndrome
• Dialysis access–associated hand ischemia, “steal syndrome,” complicates 1%–20% of accesses
• Is stealing سرقة of (arterial) blood which would normally flow to the palmar arch.
• Common in upper arm AVFs (~4%) compared with both AVGs and forearm AVFs (~1%).
• Risk factors
Upper arm access
Peripheral arterial disease
Diabetes
• Patient can complain of:
Hand numbness, pain, or weakness
Cold sensation and pale or cyanosis of the fingers
Diminished or absent pulses
Ulceration or dry gangrene of the finger tips in severe cases infection.
Pt start to wear gloves in fistula hand
• Examination requires comparison with the temperature, pulse, and function of the opposite hand.
• Investigations
Pulse oximetry
Doppler flow
Angiography
• Differential diagnosis
Carpal tunnel syndrome
Peripheral vascular disease
Neuropathy DM or Uremia
Nerve trauma
Ischemic monomelic neuropathy due to the loss of blood supply to nerves.
• Treatment Options (Depending on Severity)
Symptomatic coldness or paresthesia but without sensory or motor loss (e.g., gloves)
Surgical, with preservation of vascular access- in "steal” effect (pain at rest) or the appearance of nonhealing ulcers: banding to reduce flow, distal revascularization–interval ligation (DRIL) procedure
Surgical, with loss of vascular access- in motor loss: ligation
During hemodialysis, a hemodialyzer, or artificial kidney, is used to filter fluids and wastes from a dialysis patient's blood. Reuse of a hemodialyzer means that the same hemodialyzer (filter) is used more than once for the same patient. When dialyzers are reused, they are cleaned and disinfected after each treatment.
Although large efforts are spent for creating fistula as the primary access, use of Hemodialysis Vascular catheters are still the major access on the first Hemodialysis session and after 4 month whether we would like it or not.
"USRDS 2013"
Steal syndrome
• Dialysis access–associated hand ischemia, “steal syndrome,” complicates 1%–20% of accesses
• Is stealing سرقة of (arterial) blood which would normally flow to the palmar arch.
• Common in upper arm AVFs (~4%) compared with both AVGs and forearm AVFs (~1%).
• Risk factors
Upper arm access
Peripheral arterial disease
Diabetes
• Patient can complain of:
Hand numbness, pain, or weakness
Cold sensation and pale or cyanosis of the fingers
Diminished or absent pulses
Ulceration or dry gangrene of the finger tips in severe cases infection.
Pt start to wear gloves in fistula hand
• Examination requires comparison with the temperature, pulse, and function of the opposite hand.
• Investigations
Pulse oximetry
Doppler flow
Angiography
• Differential diagnosis
Carpal tunnel syndrome
Peripheral vascular disease
Neuropathy DM or Uremia
Nerve trauma
Ischemic monomelic neuropathy due to the loss of blood supply to nerves.
• Treatment Options (Depending on Severity)
Symptomatic coldness or paresthesia but without sensory or motor loss (e.g., gloves)
Surgical, with preservation of vascular access- in "steal” effect (pain at rest) or the appearance of nonhealing ulcers: banding to reduce flow, distal revascularization–interval ligation (DRIL) procedure
Surgical, with loss of vascular access- in motor loss: ligation
During hemodialysis, a hemodialyzer, or artificial kidney, is used to filter fluids and wastes from a dialysis patient's blood. Reuse of a hemodialyzer means that the same hemodialyzer (filter) is used more than once for the same patient. When dialyzers are reused, they are cleaned and disinfected after each treatment.
Aneurysms of Visceral arteries, Splenic Artery Aneurysm in Childbearing.KHALID ALRAJHI
Splenic Artery Aneurysm is one of the vascular anomalies of visceral arteries.
Her's seminar of visceral artery aneurysms, and in pregnancy period.
Visceral aneurysms are clinically important that affect population and health socio-economical systems.
- Introduction
- Definition
- Classifications
- Causes
- Risk Factors
- Symptoms
- Diagnosis
- Management
- Endovascular Surgery
- Case Presentation
By the end of the module, you will be able to:
Define Arterio Venous Fistula and Arterio Venous Graft
Identify Complications and Management
Familiarise and use the Pre Needling Cannulation Tool
This topic is under the Chapter - Arterial Disorders. The MBBS Students should know the types of Aneurysms and particularly Abdominal Aortic Aneurysms.
Principles of management of Neck vascular trauma
Pre Congress Workshop on
Vascular Trauma
September 2023
Joel Arudchelvam
Causes
Impalement
Signs of neck vascular injuries
Anatomy and neck zones
Management
Factors to consider
Preoperative imaging
Changing concepts
Ligation Vs Repair
Neurological status and carotid repair
Diabetic foot and Foot care
Dr Joel Arudchelvam
Definition
Prevalence
Teaching Hospital Anuradhapura [THA]
High risk foot
Neuropathy
Pathogenesis of neuropathy
Charcot foot
Testing for neuropathy
Local Ulcer care
Managing Venous Ulcers Pre-congress Workshop
Wound Care in the Elderly
Scientific Conference of the Sri Lankan Association of Geriatric Medicine
Dr Joel Arudchelvam
Chronic Venous Diseases
CEAP Classification
Chronic Venous Ulcer
Pathophysiology
Investigations
Venous Duplex Scan
Treatment
LASER - Light Amplification by Stimulated Emission of Radiation
Sclerotherapy
Multi layer compression dressing (strapping)
Compliance
Cost and problems
Methods of leg elevation
Annual Academic Conference
SLSVS 23
Joel Arudchelvam
MBBS, MD ( SUR ), MRCS (ENG), FCSSL
Consultant Vascular and Transplant Surgeon
Aortic aneurysms
Abnormal focal dilatation of a vessel of more than 50 % of its normal diameter
Abdominal aorta more than 3 cms (normal diameter - 2 cms)
Open AAA repair
Endo Vascular Aneurysm Repair (EVAR)
Arch de-branching
Sri Lankan Experience
15 Vascular and transplant units
Emergency AAA repair
Open TAA repair
Future directions
ORGAN
TRANSPLANTATION
Definition
Donor
Recipient
Graft
Organs usually transplanted
Tissues, cells usually transplanted
Types of organ donors
HISTORY OF TRASNPLANTATION
HISTORY OF TRANSPLANTATION IN SRI LANKA
Transplantation procedure
Live donor nephrectomy
Organ preservation
Renal transplantation
Donor
Post operative management
RECIPIENT – SURGERY
POST-OPERATIVE CARE
Cadaveric Transplantation
Organ ischemia
Immunological complications
Carotid artery injuries, Joel Arudchelvam, SLSC 2022, Carotid artery injuries
Causes
Hard signs of vascular injury
Associated signs
Anatomy and neck zones
Management
Factors to consider
Preoperative imaging
Management – changing concepts
Vascular surgical intervention
Open surgery
Certificate in Teaching in Higher Education (CTHE) 2022
Post ward round discussion in medical student teaching results in better understanding
Joel Arudchelvam
Advantages of ward round teaching
Problems related to the wards
The responses from the students
Future plans
Joel Arudchelvam
Definition
Donor types
HISTORY OF TRASNPLANTATION in Sri Lanka
Transplantation procedure
Organ preservation
BASIC COMPONENTS OF PRESERVATION SOLUTIONS
135TH ANNIVERSARY INTERNATIONAL MEDICAL CONGRESS 2022
30th September 2022
At BMICH, Colombo.
Symposium on
Solid Organ transplantation
Kidney transplantation - Challenges and
Experiences
Kidney transplantation
Causes for chronic kidney dise
Chronic Kidney Disease of unkn
Paediatric kidney transplant
Teaching Hospital Anuradhapura
The university transplant unit
Live donor nephrectomy
Organ preservation
Iliac vessel mobilisation
Renal vessels ananstomosis
Ureter anastomois
Surgical aspects
user experience
Relationship of live donors (T
Area of residence of donors
Live Donor profile
Donor vascular variations
Vascular reconstruction
Jaffna Medical association
Annual Scientific Sessions September, 2022
Professor C.Sivagnanasundaram memorial oration
Introduction
Vascular injuries are potentially life or limb threatening. Vascular trauma occurs in 1.6% of civilian injuries (1) and 6.8% to 10.8% in war related injuries (Afghanistan, Iraq and Lebanon war). In a study done at the National hospital of Sri Lanka Colombo (NHSL) out of 5802 trauma admissions there were 93 patients with vascular injuries (VI). Therefore the incidence of VI in civilian trauma is 1.6% (1). After the end of civil war in Sri Lanka in 2009 there is a reduction in the number of war related vascular injuries. But due to the increase in the number of Road Traffic Accidents (RTA), the number of vascular trauma also increased (i.e. from 1938 to 2013 road traffic injuries increased from 35.1 to 98.6 per 100 000 population in Sri Lanka). One of the reasons for this is the increased number two and three wheeled vehicles which are involved more with accidents (2). Trauma and vascular injuries often involve young males. They are the breadwinners of the family. In one study done at the Teaching Hospital Anuradhapura (THA) among patients presenting with popliteal arterial injuries, 18 (90%) were males with a mean age of 38.7 years (2). And in another study done at the same institution among patients with major lower limb arterial injuries, 22 (87.5%) were males and the mean age was 36.9 years (3). These studies confirm the fact of young males often getting involved with vascular injuries.
Vascular injuries occur
• Unexpected
• Young and fit
• Results in loss of limb or life
• Loss of earning capacity, economic
Our experience at Anuradhapura
Mean age - 36.9 years (17–69)
Arterial injury following trap gun - 25% amputation rate (Sriharan P, Arudchelvam JD, Marasinghe A. Outcome of major lower-limb arterial injuries presenting to a single unit in a peripheral setting in Sri Lanka. Indian J Vasc Endovasc Surg 2019;6:266-8
Causes - Road Traffic Accidents – 54.2%,Trap Gun – 33.3%,Iatrogenic - 8.33%,Other- 4.2% (Sriharan P, Arudchelvam JD, Marasinghe A. Outcome of major lower-limb arterial injuries presenting to a single unit in a peripheral setting in Sri Lanka. Indian J Vasc Endovasc Surg 2019;6:266-8)
Mechanism of injury
• Sharp / penetrating
• Blunt
“Vascular injury” is a nonspecific term. Because this is used to describe the injuries
to blood vessels in all parts of the body that includes neck vascular injuries, thoracic and
abdominal vascular injuries, and injuries to the blood vessels of the limbs. And in addition
vascular injury also describes injuries to the arteries and veins. Injuries to the blood vessels of
the limbs are called extremity vascular injury. This chapter will concentrate on the extremity
vascular injuries.
Acute limb ischaemia
Joel Arudchelvam
MBBS (COL), MD (SUR). MRCS (ENG)
Consultant Vascular and Transplant Surgeon
The National Hospital of Sri Lanka , Colombo
Definition
Causes
Differentiating thrombosis and embolism
More from Joel Arudchelvam MBBS, MD, MRCS, FCSSL (20)
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
1. Vascular access
Complications
Surveillance / Troubleshooting
Dr Joel Arudchelvam
MBBS (COL), MD (SUR). MRCS (ENG).
Senior Lecturer, Department of Surgery, University of Colombo,
Consultant Vascular and Transplant Surgeon,
The National Hospital of Sri Lanka, Colombo.
2. Vascular access
• End Stage Renal
Failure - Renal
replacement therapy
o Haemodialysis
o Peritoneal dialysis
10. Mature fistula
• When the AVF becomes suitable for
dialysis
o Flow - >600 mL/min,
o Diameter – 6mm
o Depth - < 6mm
o Well visualized and felt
• Usually in 6 weeks
11. AVF Monitoring
• Assess for;
o Limb edema / facial oedema
o Alterations in pulse / thrill characteristics
o Prominent collaterals
o lack of pulse augmentation (inflow stenosis)
o prolonged bleeding
o Finer numbness
o Finger pain
o Signs of infection
• Should be done at least monthly
12. AVF Monitoring
• Duplex scanning
o Flow measurements - less than 400 to 500 mL/min
o Abnormalities
• For inadequate dialysis
o Recirculation indicators
• Static pressures
o Arterial and venous
• Angiography
14. Thrombosis
• Causes
o Anastomotic issues
o Venous abnormalities
o Systemic causes
o External compression
• Treatment
o Thrombectomy
o Correction of underlying cause – stenosis, strictures
o Redo AVF
15. Stenosis
• Causes
o Anastomotic stenosis – technical, neo-intimal hyperplasia
o Venous stenosis – past thrombophlebitis, cannulation injury
• Clinical findings
o Reduced thrill / Abnormal thrill (weak and/or discontinuous)
o Reduced pressure during dialysis
18. Treatment
• Fistulogram and Fistuloplasty
• Open Venous patch angioplasty
• Repositioning of the anastomosis
• Redo AVF
19. Central venous stenosis
• History of previous
venous cannulation
• Swelling of the upper limb
• Facial swelling
• Prolonged bleeding after
needle removal
• Increased venous
pressure
23. Steal syndrome
• Distal limb and hand ischemia due to poor blood flow to
the limb as a result of AVF
• Incidence - 0.25% to 20%
• Depends on the type of AVF – Proximal / distal
24. Risk factors
o Female gender
o Previous AVF on same limb
o Proximal AVF
o Arterial disease
o Large Arteriotomy during access creation
25. Steal syndrome
• Presentation
o Pain, pallor, numbness,
gangrene of digits
o Reduced absent distal
pulse – appear on AVF
occlusion
27. Steal syndrome
Stages
1 – cold, pale hand
2- pain with exercise or dialysis
3- rest pain /ulcer/ gangrene
28. Steal syndrome
Management
o Mild - conservative
o Angioplasty of inflow vessels
o Ligation of AVF
o Banding of outflow
o Distal revascularization and interval ligation (DRILL)
procedure
o Proximalisation of arterial inflow
35. Cannulation techniques
• Buttonhole cannulation
• General area cannulation
o In close proximity
– Rope-ladder cannulation
– Along the length of access