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Uterine sarcoma

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Hesham Gaber
Health & Medicine
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Uterine Sarcoma
Challenging ,[object Object],[object Object],[object Object]
Epidemiology ,[object Object],[object Object],[object Object],[object Object]
Risk Factors ,[object Object],[object Object],[object Object]
long-term adjuvant tamoxifen ,[object Object],[object Object]
Histologic Classification Mixed mesodermal sarcoma Carcinosarcoma Mixed Liposarcoma (ii) Endometrial stromal sarcoma Osteosarcoma (i) endolymphatic stromal sarcoma Chondrosarcoma Stromal sarcoma Rhabdomyosarcoma Leimyosarcoma Pure Heterologous Homologous Type
GOG , 1993 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Leiomyosarcoma ,[object Object],[object Object]
Leiomyosarcoma
Leiomyosarcoma: Low or high grade ,[object Object],[object Object],[object Object]
Endometrial stromal Sarcoma : ,[object Object],[object Object],[object Object],[object Object]
Mixed mullerian sarcomas ,[object Object],[object Object],[object Object]
Subdivided ,[object Object],[object Object]
MMT
Adenosarcoma ,[object Object],[object Object],[object Object]
Clinical Diagnosis ,[object Object],[object Object]
Rapidly growing!! ,[object Object]
Should be considered in ,[object Object]
Evaluation ,[object Object],[object Object]
Staging: surgical Sarcoma has spread outside the true pelvis IV Sarcoma has spread outside the uterus but is confined to the true pelvis III Sarcoma is confined to the corpus and cervix II Sarcoma is confined to the corpus I Description Stage based on FIGO staging for endometrial cancer
Lymph node Biopsy ,[object Object],[object Object]
Further support ,[object Object]
Treatment ,[object Object]
Surgery ,[object Object]
Modalities ,[object Object],[object Object],[object Object]
Is it beneficial !! ,[object Object]
The five year survivals ,[object Object],[object Object],[object Object],[object Object],[object Object]
three-year local recurrence rates ,[object Object],[object Object],[object Object],[object Object]
Massachusetts General Hospital ,[object Object],[object Object]
   Adjuvant radiation therapy ,[object Object],[object Object]
Complications of Radiation Tx: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adjuvant chemotherapy ,[object Object],[object Object]
This is because ,[object Object],[object Object]
   Leiomyosarcoma ,[object Object],[object Object],[object Object]
   Carcinosarcoma ,[object Object]
Mixed mesodermal tumors ,[object Object],[object Object]
Hormone therapy ,[object Object],[object Object]
Recurrent Disease ,[object Object],[object Object],[object Object],[object Object]
In a recent RCT 2000 ,[object Object],[object Object],[object Object]
Prognosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
leiomyosarcoma ,[object Object]
Conclusion ,[object Object],[object Object]
Thank You

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Uterine sarcoma

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  • 6. Histologic Classification Mixed mesodermal sarcoma Carcinosarcoma Mixed Liposarcoma (ii) Endometrial stromal sarcoma Osteosarcoma (i) endolymphatic stromal sarcoma Chondrosarcoma Stromal sarcoma Rhabdomyosarcoma Leimyosarcoma Pure Heterologous Homologous Type
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  • 14. MMT
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  • 20. Staging: surgical Sarcoma has spread outside the true pelvis IV Sarcoma has spread outside the uterus but is confined to the true pelvis III Sarcoma is confined to the corpus and cervix II Sarcoma is confined to the corpus I Description Stage based on FIGO staging for endometrial cancer
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