TYPES OF WOUND HEALING by Mishal Khan.pptx
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There are three main types of wound healing: primary intention, secondary intention, and tertiary intention. Primary intention involves closing clean wounds with sutures, leading to rapid healing and a neat scar. Secondary intention involves leaving wounds open to heal, resulting in a longer healing time and larger scar. Tertiary intention involves initially leaving contaminated wounds open to clean before later closure, aiming to prevent chronic inflammation and scarring. Complications can include hypertrophic scarring, keloids, contractures, wound dehiscence, adhesions, and infection.
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Wound healing involves four phases - coagulation and hemostasis, inflammation, proliferation, and maturation. During coagulation, clotting occurs to stop bleeding. Inflammation brings immune cells to fight infection. Proliferation involves new tissue growth via fibroblasts, collagen deposition, and re-epithelialization. Maturation involves collagen remodeling for strength over 1-2 years. Factors like infection, nutrition, diabetes, and age can affect healing. Complications include delayed healing or abnormal scarring.
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This document discusses the process of healing through regeneration and repair. It describes the key stages and phases of wound healing, including inflammation, granulation tissue formation, epithelialization, and scar formation. Factors that can affect healing, both locally such as infection or poor blood supply, and generally such as age, obesity, or malnutrition are also outlined. Complications from improper or delayed healing include infection, cysts, scarring issues, and hernias.
Healing and repair
1. Tissue repair involves regeneration of injured tissue or replacement by connective tissue scarring. It involves cell proliferation and interaction between cells and the extracellular matrix.
2. Tissues are divided into continuously dividing, stable, and permanent groups based on their ability to proliferate. Continuously dividing tissues like skin regenerate easily while permanent tissues like neurons cannot regenerate after injury.
3. Growth factors and the extracellular matrix play important roles in tissue repair by stimulating cell growth and movement. Repair occurs through regeneration in labile tissues and scarring in others when injury is too severe for regeneration.
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- 1. TYPES OF WOUND HEALING Presented By Mishal Khan
- 2. WOUND HEALING: A complex biological process that consists of hemostasis, inflammation, proliferation, and remodeling leads to replacement of destroyed or damaged tissue by newly produced tissue.
- 3. The body response to the injury in attempt to restore normal function and structure. It involves 2 distinct process: • Regeneration: A type of healing in which new growth completely restore portion of damaged tissues to their normal state. Not associated with scar. • Repair: A type of healing refer to the reestablishment of tissue continuity. Associated with scar.
- 4. TYPES OF WOUND HEALING: • There are 3 types of wound Healing 1. Primary Intention 2. Secondary Intention 3. Tertiary Intention
- 5. Healing By Primary Intention: Characteristics of Wound • Clean and uninfected • Without much loss of cells and tissues. • Wound with regular Margins • Edges of the Wounds are approximated with surgical sutures. End Result: • Rapid healing • Neat scar
- 6. Healing By Primary Intention: Cont. Primary union involves following sequence of events • Initial Hemorrhage • Actual inflammatory process • Epithelial Changes • Organization
- 8. Scar By Primary intention
- 9. Healing By Secondary Intention: Characteristics of wound: • Large tissue defect, at times infected • Extensive loss of cells and tissues • Wound not approximated by sutures and left open End Result: • Longer time of healing • Larger Scar
- 10. Healing By Secondary Intention Cont. • Initial Hemorrhage • Inflammatory Response • Epithelial changes • Granulation tissue formation • Wound contraction
- 12. ABDOMINAL SCAR by Secondary intention
- 13. Healing By tertiary Intention: Also known as delayed primary wound healing. This type of healing may be desired in the case of contaminated wounds. So in this type of healing the wound edges are not re-approximated immediately.
- 14. Healing By tertiary Intention Cont. By the fourth day, phagocytosis of contaminated tissues is well underway, and the processes of epithelization, collagen deposition, and maturation are occurring. Foreign materials are walled off by macrophages. The wound is closed surgically at this juncture. if the "cleansing" of the wound is incomplete, chronic inflammation can ensue, resulting in prominent scarring.
- 17. Complication Of wound Healing: • Hypertrophic scars • Keloid Formation • Contractures • Wound dehiscence • Adhesions • Infection
- 18. Complications of Wound Healing