This document summarizes key information about the trigeminal nerve including its sensory and motor distribution, lesions, and clinical presentations. It discusses supranuclear, nuclear, and peripheral lesions and their effects. Supranuclear lesions can cause pseudobulbar palsies or unilateral jaw deviation. Nuclear lesions typically involve the trigeminal nuclei and cause ipsilateral facial sensory deficits. Peripheral lesions affect the trigeminal ganglion or branches, potentially causing numbness, pain or motor deficits in the corresponding regions of the face.